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1.
公开(公告)号:US10058712B2
公开(公告)日:2018-08-28
申请号:US14856905
申请日:2015-09-17
Applicant: Konkuk University Glocal Industry-Academic Collaboration Foundation , Industry-Academic Cooperation Foundation, Chosun University
Inventor: Soon-Cheol Chung , Jae-Hoon Jun , Jong-Rak Park , Seungmoon Choi , Hyung-Sik Kim , Ji-Sun Kim
CPC classification number: A61N5/0622 , A61N5/0616 , A61N2005/0659 , A61N2005/0663 , A61N2005/067
Abstract: The present invention relates to a system for fundamentally eliminating skin damage caused by direct radiation of a laser beam on the skin of a user and inducing a somatic sensation on the skin within a safety standard by radiating a pulse laser beam on a medium attached to the skin of the user on which the somatic sensation is desired to be induced. Particularly, the present invention relates to a somatic sensation induction system which can induce a somatic sensation of various feelings delivered to a user by adjusting an absorption coefficient of a medium contacting with the skin of a user, energy intensity and a repetition rate of a radiated laser beam and the like.
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公开(公告)号:US20230186474A1
公开(公告)日:2023-06-15
申请号:US17625911
申请日:2020-03-18
Applicant: THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY-ACADEMIC COOPERATION FOUNDATION , KONKUK UNIVERSITY GLOCAL INDUSTRY-ACADEMIC COLLABORATION FOUNDATION
Inventor: Hyun Jeong KIM , Hong Gee ROH
CPC classification number: G06T7/0016 , A61B5/055 , G06T19/20 , G06T2207/20224 , G06T2207/10088 , G06T2200/04 , G06T2207/10076 , G06T2207/30101 , G06T2207/20132 , G06T2207/20092 , G06T2207/30096 , G06T2219/2012
Abstract: Provided are a simultaneous implementation method of 3D subtraction arteriography, 3D subtraction venography, and 4D color angiography through post-processing of image information of 4D magnetic resonance (MR) angiography, and a medical imaging system.
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公开(公告)号:US10792340B2
公开(公告)日:2020-10-06
申请号:US15563795
申请日:2016-04-04
Inventor: Yeong Min Park , In Duk Jung , Seung Jun Lee
Abstract: Provided is an antibacterial composition against carbapenem-resistant gram-negative bacteria which includes, as an active ingredient, adenylate kinase (ADK) protein derived from Mycobacterium tuberculosis. The ADK protein derived from Mycobacterium tuberculosis, according to the subject matter, has excellent antimicrobial activity against carbapenem-resistant gram-negative bacteria, and thus may be usefully used in a variety of fields as an antibacterial composition.
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公开(公告)号:US20220347225A1
公开(公告)日:2022-11-03
申请号:US17633264
申请日:2020-08-07
Applicant: Konkuk University Industrial Cooperation Corp. , Konkuk University Glocal Industry-Academic Collaboration Foundation
Inventor: Ssang-Goo CHO , Hyun Jin SHIN , Kyung Min LIM , Min Chan GIL , Ahmed ABDEL DAYEM
Abstract: The present disclosure relates to a composition containing extracellular vesicles isolated from skeletal muscle-derived stem cells as active ingredients, which exhibits the effect of skin aging delay, wound healing, scar reduction and skin whitening, thereby improving skin condition. The present disclosure can not only utilize tissues wasted after surgical operation, thus allowing easy supply of raw materials, but also takes advantage of natural substances, thereby being free from the risk of side effects even upon long-term administration. The composition of the present disclosure promotes the secretion of collagen, reduces reactive oxygen species and promotes re-epithelialization at wound site while remarkably inhibiting melanocyte proliferation, tyrosinase activity and melanogenesis. Accordingly, it can facilitate effective recovery from skin tissue damage caused by oxidative stress, physical wound, intrinsic aging at cell or tissue levels, or hyperpigmentation.
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公开(公告)号:US20220012883A1
公开(公告)日:2022-01-13
申请号:US17483711
申请日:2021-09-23
Applicant: THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY-ACADEMIC COOPERATION FOUNDATION , KONKUK UNIVERSITY GLOCAL INDUSTRY-ACADEMIC COLLABORATION FOUNDATION
Inventor: Jin Tae KWAK , Nhat To MINH NGUYEN , Hyun Jeong KIM , Hong Gee ROH
Abstract: A learning method for generating a multiphase collateral image comprises the steps of: receiving inputs of an MRI image of a head part and a multiphase collateral image generated on the basis of the MRI image; generating a brain mask by using the MRI image; generating an MRI image and a multiphase collateral image which are masked by the brain mask; and learning the masked multiphase collateral image for the masked MRI image by using a learning network.
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6.
公开(公告)号:US10459522B2
公开(公告)日:2019-10-29
申请号:US15367281
申请日:2016-12-02
Inventor: Soon-Cheol Chung , Hyung-Sik Kim , Jae-Hoon Jun
Abstract: A system and method for generating air plasma by radiating a laser in the air, and making a user feel a somatic sense such as a tactile sense, a thermal sense or the like using a principle of inducing a state change in a medium as a result of a shock wave or an electric field generated by the air plasma.
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公开(公告)号:US12112481B2
公开(公告)日:2024-10-08
申请号:US17625911
申请日:2020-03-18
Applicant: THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY-ACADEMIC COOPERATION FOUNDATION , KONKUK UNIVERSITY GLOCAL INDUSTRY-ACADEMIC COLLABORATION FOUNDATION
Inventor: Hyun Jeong Kim , Hong Gee Roh
CPC classification number: G06T7/0016 , A61B5/055 , G06T19/20 , G06T2200/04 , G06T2207/10076 , G06T2207/10088 , G06T2207/20092 , G06T2207/20132 , G06T2207/20224 , G06T2207/30096 , G06T2207/30101 , G06T2219/2012
Abstract: A simultaneous implementation method of 3D subtraction magnetic resonance (MR) arteriography, 3D subtraction MR venography, and color-coded 4D MR angiography through post-processing of image information of 4D MR angiography according to an embodiment of the present disclosure may reduce scan time required to individually obtain an MR arteriography and an MR venography. In addition, not only anatomical information of arteries but also more accurate anatomical information of veins and more detailed hemodynamic information may be obtained.
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公开(公告)号:US10736944B2
公开(公告)日:2020-08-11
申请号:US16120603
申请日:2018-09-04
Inventor: Yeong Min Park , In Duk Jung , Sung Jae Shin , Jung Hee Park , Seung Jun Lee , Tae Heung Kang , Byoung Yul Soh
Abstract: The present invention relates to a composition for preventing or treating sepsis or septic shock including a Mycobacterium tuberculosis-derived adenosine kinase (ADK) protein as an active ingredient. The Mycobacterium tuberculosis-derived ADK protein according to one exemplary embodiment of the present invention has an effect of inhibit binding between the LPS and cells by binding to LPS, and also has an excellent therapeutic effect against sepsis by enhancing viability in a sepsis animal model and suppressing inflammatory response in the lung and cell death in the spleen.
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公开(公告)号:US10543258B2
公开(公告)日:2020-01-28
申请号:US15534979
申请日:2015-12-10
Inventor: Yeong Min Park , In Duk Jung , Yong Taik Lim , Jung Hee Park , Sung Jae Shin
IPC: A61K38/00 , A61K38/45 , A61P31/04 , A61K31/345 , A61K31/43 , A61K31/47 , A61K31/545 , A61K31/65 , A61K31/7036 , C12N9/12
Abstract: The present invention relates to an antibacterial composition containing, as an active ingredient, adenylate kinase or adenosine kinase (ADK) protein derived from Mycobacterium tuberculosis, and a composition for preventing or treating infectious diseases. In addition, the present invention relates to a composition for preventing or treating sepsis or septic shock. Furthermore, the present invention relates to a method for preventing, improving or treating an infectious disease comprising administering the present antibacterial composition. The ADK protein derived from Mycobacterium tuberculosis according to the present invention has excellent antibacterial activity selectively against gram-negative bacteria, and thus can be favorably used as an antibacterial composition against gram-negative bacteria or for the prevention or treatment of infectious diseases caused by gram-negative bacteria. In addition, the ADK protein has an excellent sepsis treatment effects, thus can be favorably used for the prevention or treatment of sepsis or septic shock.
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10.
公开(公告)号:US20180078619A1
公开(公告)日:2018-03-22
申请号:US15563795
申请日:2016-04-04
Inventor: Yeong Min PARK , In Duk JUNG , Seung Jun LEE
Abstract: Provided is an antibacterial composition against carbapenem-resistant gram-negative bacteria which includes, as an active ingredient, adenylate kinase (ADK) protein derived from Mycobacterium tuberculosis. The ADK protein derived from Mycobacterium tuberculosis, according to the subject matter, has excellent antimicrobial activity against carbapenem-resistant gram-negative bacteria, and thus may be usefully used in a variety of fields as an antibacterial composition.
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