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公开(公告)号:US20020154672A1
公开(公告)日:2002-10-24
申请号:US10099473
申请日:2002-03-15
Applicant: Yeda Research and Development Co. Ltd.
Inventor: Asher A. Friesem , Shmuel Blit , Ram Oron , Erez Hasman , Nir Davidson
IPC: H01S003/08
CPC classification number: H01S3/08036 , H01S3/08054 , H01S3/082 , H01S3/106 , H01S2301/20 , H01S2301/203
Abstract: An optical resonator supporting two sets of simultaneously co-existent oscillation modes (30 and 31), having polarizations orthogonal to each other. Mode control elements (28 and 29), such as apertures and phase elements, are introduced into the resonator to allow only preferred modes to exist. The placement and orientation of the sets are designed such that the high intensity zones of one set fall on the nodes or low intensity zones of the other set in an interlaced pattern. Thus, in a laser resonator, better utilization of the gain medium (24) is achieved and the beam quality and brightness over multimode lasing are improved. This configuration improves the performance of high Fresnel number resonators, in both pulsed and continuous lasers, for applications such as scribing, drilling, cutting, target designation and rangefinding. An application of the intra-cavity coherent summation of orthogonally polarized modes is described, whereby azimuthally or radially polarized beams may be obtained.
Abstract translation: 支持两组同时共存的振荡模式(30和31)的光学谐振器,具有彼此正交的极化。 将模式控制元件(28和29)(诸如孔径和相位元件)引入到谐振器中,以仅允许存在优选的模式。 这些组的放置和取向被设计成使得一组的高强度区域以交错图案落在另一组的节点或低强度区域上。 因此,在激光谐振器中,实现了增益介质(24)的更好的利用,并提高了多模激光的光束质量和亮度。 这种配置提高了脉冲和连续激光器中高菲涅尔数谐振器的性能,适用于诸如划线,钻孔,切割,目标指定和测距等应用。 描述了正交偏振模式的腔内相干求和的应用,由此可以获得方位角或径向偏振光束。
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192.
公开(公告)号:US20020141035A1
公开(公告)日:2002-10-03
申请号:US10021903
申请日:2001-12-13
Applicant: YEDA RESEARCH AND DEVELOPMENT CO. LTD.
Inventor: Nir Davidson , Nir Friedman , Ariel Kaplan
IPC: G02F001/11
CPC classification number: G02F1/33
Abstract: An acousto-optic scanning system, which relies on two counter propagating acoustic waves with the same frequency modulation. This scheme completely suppresses the linear frequency chirp, and thus enables the generation of fast non-linear scans and non-constant linear scans. By changing the phase between the modulating signals, this scheme also provides fast longitudinal scans of the focal point.
Abstract translation: 一种声光扫描系统,其依赖于具有相同频率调制的两个反传播声波。 该方案完全抑制线性频率啁啾,从而能够产生快速非线性扫描和非恒定线性扫描。 通过改变调制信号之间的相位,该方案还提供焦点的快速纵向扫描。
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公开(公告)号:US20250127180A1
公开(公告)日:2025-04-24
申请号:US18987103
申请日:2024-12-19
Applicant: YEDA RESEARCH AND DEVELOPMENT CO. LTD. , THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL R , HARVESTR TECHNOLOGIES LTD.
Inventor: Robert FLUHR , Noam ALKAN , Lena POVARENOV , Danielle DUANIS ASSAF , Pankaj CHOWDHARY , Gal ADMATI , Yael BAR LAVAN
Abstract: The present invention is directed to an anti-fungal composition including a plurality of particles including: at least one dsRNA molecule including a nucleic acid sequence complementary to at least one transcript of at least one essential gene of a fungus, and methods of using same.
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194.
公开(公告)号:US12274786B2
公开(公告)日:2025-04-15
申请号:US17406168
申请日:2021-08-19
Applicant: Yeda Research and Development Co. Ltd.
Inventor: Jacob Klein , Ronit Goldberg , Jasmine Seror
IPC: A61K9/127 , A61K9/00 , A61K9/08 , A61K31/728 , A61K31/77 , A61K31/79 , A61K47/10 , A61K47/32 , A61K47/36 , B65D35/00 , B65D75/36
Abstract: Formulations (e.g., solutions) comprising one or more water-soluble polymer(s), liposomes, and an aqueous carrier, are provided. The provided solutions are useful for rinsing, and/or immersing therein, a contact lens and/or in the treatment of ocular discomfort, for example, an ocular discomfort associated with a contact lens. Also provided are kits comprising the solution and a contact lens; articles-of-manufacturing comprising the solution and configured for dispending the solution; and methods utilizing the solution.
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公开(公告)号:US20250101375A1
公开(公告)日:2025-03-27
申请号:US18825336
申请日:2024-09-05
Applicant: Yeda Research and Development Co. Ltd.
Inventor: Yaqub HANNA , Sergey VIUKOV , Emilie WILDSCHUTZ , Noa NOVERSHTERN , Carine JOUBRAN , Segev NAVEH TASSA , Alejandro CASTREJON AGUILERA , Bernardo OLDAK , Shadi TARAZI , Francesco RONCATO
Abstract: Methods of generating a synthetic embryo are provided. Accordingly, there is provided a method of generating a synthetic embryo comprising inducing expression of a factor that induces differentiation to trophectoderm cells in a subpopulation of naïve pluripotent stem cells (PSCs) to obtain a trophectoderm primed cells; inducing expression of a factor that induces differentiation to extra embryonic primitive endodermal cells in a second subpopulation of naïve PSCs to obtain extra embryonic primitive endodermal primed cells; and mixing said trophectoderm primed cells and said extra embryonic primitive endodermal primed cells with naïve PSCs under conditions that allow formation of aggregated cells. Also provided are articles of manufactures, mixtures and aggregates of cells and methods of using same.
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公开(公告)号:US20250092415A1
公开(公告)日:2025-03-20
申请号:US18910862
申请日:2024-10-09
Applicant: Yeda Research and Development Co. Ltd. , Yissum Research Development Company of The Hebrew University of Jerusalem Ltd.
Inventor: Asaph AHARONI , Prashant SONAWANE , Pablo D. CARDENAS , Saul BURDMAN
Abstract: Disclosed herein are genetically modified plants having altered biological activity of 3-β-hydroxysteroid dehydrogenase/isomerase (GAME25), or 2-oxoglutarate-dependent dioxygenase (GAME31), or a combination thereof, wherein the genetically modified plants have an altered content of at least one cholesterol derived compound selected from the group including a steroidal alkaloid or a glycosylated derivative thereof and an unsaturated or saturated steroidal saponin or a glycoside derivative thereof. Further disclosed herein are genetically modified plants having altered expression of a gene encoding a 3-β-hydroxysteroid dehydrogenase/isomerase (GAME25), or a 2-oxoglutarate-dependent dioxygenase (GAME31), or a combination thereof, wherein the genetically modified plant has an altered content of at least one cholesterol derived compound selected from the group including a steroidal alkaloid or a glycosylated derivative thereof and an unsaturated or saturated steroidal saponin or a glycoside derivative thereof. Methods of producing these genetically modified plants are also disclosed.
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公开(公告)号:US20250092353A1
公开(公告)日:2025-03-20
申请号:US18942735
申请日:2024-11-10
Applicant: YEDA RESEARCH AND DEVELOPMENT CO. LTD.
Inventor: Steffen JUNG , Jarmila Sekeresova KRALOVA
IPC: C12N1/16 , A01K67/027 , A61K36/064 , A61P31/10 , C12R1/645
Abstract: There is provided an isolated fungus belonging to the genus Kazachstania, a composition comprising same, and methods of using same, such as for preventing or treating an infection, a disease, or both.
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公开(公告)号:US20250090510A1
公开(公告)日:2025-03-20
申请号:US18964396
申请日:2024-11-30
Applicant: YEDA RESEARCH AND DEVELOPMENT CO. LTD.
Inventor: Rivka DIKSTEIN , Urmila SERAWAT , Ana TAMARKIN BEN-HARUSH , Ora HAIMOV , Neta REGEV-RUDZKI , Shaked ASHKENAZI , Benjamin WEISS , Anastasia LEV
IPC: A61K31/44 , A61K31/415 , A61K31/428
Abstract: Methods of inhibiting eIF4G1 binding to eIF1, and inhibiting translation initiation are provided. Pharmaceutical compositions comprising inhibitors of eIF4G1-eIF1 binding and there use in treating disease are also provided.
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公开(公告)号:US20250049835A1
公开(公告)日:2025-02-13
申请号:US18926385
申请日:2024-10-25
Inventor: Rotem SOREK , Gil AMITAI , Azita LEAVITT , Erez YIRMIYA , Philip J. KRANZUSCH , Allen LU , Samuel J. HOBBS
IPC: A61K31/7076 , A61K39/39 , A61K39/395
Abstract: Methods of treating a disease or disorder associated with a down or up-regulation of an immune response of a subject are disclosed. The methods comprising administering to the subject a therapeutically effective amount of any one or more of the molecule 1′-2′ glycosyl cyclic adenosine diphosphate ribose (1′-2′ gcADPR), 1′-3′ gcADPR or Tad1 protein.
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公开(公告)号:US12190205B2
公开(公告)日:2025-01-07
申请号:US18299827
申请日:2023-04-13
Inventor: Gil Semo , Ziv Aqua , Oded Melamed , Dan Charash , Serge Rosenblum , Barak Dayan
Abstract: Systems and methods for a quantum computing include a plurality of photonic processing stages, a plurality of heralding-free connections, and circuitry configured to regulate photon flow between adjacent stages such that decisions about stage settings or flow between adjacent stages are free of input from a previous stage. Each heralding-free connection is located between adjacent photonic processing stages. Each photonic processing stage includes at least two of an optical switch, a beam splitter, a waveguide or a photon generator. Methods include transmitting or receiving a plurality of photons via a plurality of heralding-free connections, and regulating photon flow between adjacent stages such that decisions about stage settings or flow between adjacent stages are free of input from a previous stage.
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