公开(公告)号：US20060243897A1

公开(公告)日：2006-11-02

申请号：US11116657

申请日：2005-04-27

Applicant: Shih-Yuan Wang ,  Zhiyong Li

Inventor： Shih-Yuan Wang ,  Zhiyong Li

IPC: H05H3/04

CPC classification number: G21K1/006

Abstract: For manipulation of a specimen, the specimen and a focusing location of a composite material lens are brought into spatial coincidence. The composite material lens has at least one of a negative effective permittivity and a negative effective permeability at a frequency of an applied light beam. The composite material lens focuses the light beam toward the focusing location and forms an optical trap for the specimen.

Abstract translation: 对于样品的操作，复合材料透镜的样品和聚焦位置变得空间重合。 复合材料透镜在所施加的光束的频率处具有负的有效介电常数和负的有效磁导率中的至少一个。 复合材料透镜将光束聚焦到聚焦位置并形成样品的光阱。

公开(公告)号：US07102747B2

公开(公告)日：2006-09-05

申请号：US10964523

申请日：2004-10-13

Applicant: Shih-Yuan Wang ,  Zhiyong Li ,  M. Saif Islam

Inventor： Shih-Yuan Wang ,  Zhiyong Li ,  M. Saif Islam

IPC: G01J3/44 ,  G01N21/65

CPC classification number: G01N21/658

Abstract: Devices, systems, and methods using Surface Enhanced Raman Spectroscopy (SERS) are disclosed. A device for generating Raman scattered radiation comprises a laser source and a SERS-active structure. The laser source may be configured for emanating radiation from an emanating surface or by forming a depression in the laser source, which creates a region of increased evanescent field from the laser source. SERS systems and methods include a device for generating Raman scattered radiation with a detector configured to receive the Raman scattered radiation.

Abstract translation: 公开了使用表面增强拉曼光谱（SERS）的器件，系统和方法。 用于产生拉曼散射辐射的装置包括激光源和SERS-活性结构。 激光源可以被配置用于从发射表面发射辐射，或者通过在激光源中形成凹陷，其产生从激光源增加的渐逝场的区域。 SERS系统和方法包括用配置成接收拉曼散射辐射的检测器产生拉曼散射辐射的装置。

公开(公告)号：US20060055921A1

公开(公告)日：2006-03-16

申请号：US10942079

申请日：2004-09-14

Applicant: Shih-Yuan Wang ,  Zhiyong Li ,  M. Islam

Inventor： Shih-Yuan Wang ,  Zhiyong Li ,  M. Islam

IPC: G01J3/44 ,  G01N21/65

CPC classification number: G01N21/658

Abstract: Structures for amplifying light include a resonant cavity in which an analyte may be positioned. The structures for amplifying light may be used to amplify the incident light employed in surface enhanced Raman spectroscopy (SERS). SERS systems employing the structures for amplifying light of the present invention and methods of performing SERS are also disclosed.

Abstract translation: 用于放大光的结构包括其中可以定位分析物的谐振腔。 用于放大光的结构可以用于放大表面增强拉曼光谱（SERS）中使用的入射光。 还公开了采用本发明的光放大结构的SERS系统和执行SERS的方法。

公开(公告)号：US20060055920A1

公开(公告)日：2006-03-16

申请号：US10941714

申请日：2004-09-14

Applicant: Shih-Yuan Wang ,  M. Islam ,  Zhiyong Li

Inventor： Shih-Yuan Wang ,  M. Islam ,  Zhiyong Li

IPC: G01J3/44

CPC classification number: G01N21/658 ,  G01J3/26

Abstract: Wavelength-tunable radiation amplifying structures for Raman spectroscopy are disclosed that include resonant cavities having Raman signal-enhancing structures disposed therein. Systems that include the amplifying structures and methods of performing spectroscopic analysis using the structures and systems are also disclosed.

Abstract translation: 公开了用于拉曼光谱的波长可调辐射放大结构，其包括其中布置有拉曼信号增强结构的谐振腔。 还公开了包括放大结构的系统和使用该结构和系统进行光谱分析的方法。

公开(公告)号：US20060046069A1

公开(公告)日：2006-03-02

申请号：US10929810

申请日：2004-08-30

Applicant: Gun Jung ,  Zhiyong Li ,  Richard Williams ,  Sivapackia Ganapathiappan

Inventor： Gun Jung ,  Zhiyong Li ,  Richard Williams ,  Sivapackia Ganapathiappan

IPC: B32B17/06 ,  B32B9/00

CPC classification number: G03F7/0002 ,  B05D1/185 ,  B82Y10/00 ,  B82Y30/00 ,  B82Y40/00 ,  Y10T428/31612 ,  Y10T428/31692 ,  Y10T428/31855 ,  Y10T428/31935 ,  Y10T428/31938

Abstract: A method for increasing adhesion between a substrate and a polymeric imprintable material during an imprinting procedure. The method includes chemically bonding a plurality of molecules to a surface of a substrate to form a self-assembled monolayer thereon. A monomer is copolymerized with the self-assembled monolayer to form a polymeric imprintable material that is chemically bonded to the self-assembled monolayer. Adhesion between the polymeric imprintable material and the substrate is substantially increased by the self-assembled monolayer.

Abstract translation: 一种在印刷过程中增加基材和聚合物可压印材料之间的粘合力的方法。 该方法包括将多个分子化学键合到基底的表面以在其上形成自组装单层。 单体与自组装单层共聚以形成化学键合到自组装单层的聚合物可压印材料。 通过自组装单层，聚合物可压印材料和基材之间的粘合力显着增加。

公开(公告)号：US6157960A

公开(公告)日：2000-12-05

申请号：US852263

申请日：1997-05-07

Applicant: David Louis Kaminsky ,  Richard Adam King ,  Zhiyong Li

Inventor： David Louis Kaminsky ,  Richard Adam King ,  Zhiyong Li

IPC: G06F15/16 ,  G06F9/44 ,  G06F9/46

CPC classification number: G06F9/546 ,  G06F9/548

Abstract: The automatic object distribution of the present invention allows object oriented programs to be run as distributed programs without any explicit networking code, and without using an interface definition language (IDL). The present invention allows programmers to experiment with different distributions without complicating the programming task. It accomplishes this by generating two proxies that allow method calls written for local invocation to be invoked over a network. These dynamically-generated proxies allow calls to flow across a network as if they were local.

Abstract translation: 本发明的自动对象分发允许面向对象的程序作为分布式程序运行而不需要任何明确的联网代码，并且不使用接口定义语言（IDL）。 本发明允许程序员在不使编程任务复杂化的情况下对不同的分布进行实验。 它通过生成两个代理来实现，该代理允许通过网络调用为本地调用编写的方法调用。 这些动态生成的代理允许呼叫流过网络，就像它们是本地的。

公开(公告)号：US10342852B2

公开(公告)日：2019-07-09

申请号：US15729420

申请日：2017-10-10

Applicant: Chaoyu Miao ,  Zhiyong Li ,  Pei Wang

Inventor： Chaoyu Miao ,  Zhiyong Li ,  Pei Wang

IPC: A61K38/19 ,  C07K14/52 ,  A61K38/22 ,  A23L33/17 ,  A61K39/00 ,  C07K14/475

Abstract: The present invention provides an application of Metrnl protein in preparing a hypolipidemic, hypoglycemic medicine or dietary supplement. The present invention further provides a method for preparing a mouse with fat-specific overexpression of Metrnl.

公开(公告)号：US20180030102A1

公开(公告)日：2018-02-01

申请号：US15729420

申请日：2017-10-10

Applicant: Chaoyu Miao ,  Zhiyong Li ,  Pei Wang

Inventor： Chaoyu Miao ,  Zhiyong Li ,  Pei Wang

IPC: C07K14/475 ,  A61K38/22 ,  A61K39/00

CPC classification number: A61K38/19 ,  A23L33/17 ,  A23V2002/00 ,  A61K39/00 ,  C07K14/475 ,  C07K14/52

Abstract: The present invention provides an application of Metrnl protein in preparing a hypolipidemic, hypoglycemic medicine or dietary supplement. The present invention further provides a method for preparing a mouse with fat-specific overexpression of Metrnl.

公开(公告)号：US09638625B2

公开(公告)日：2017-05-02

申请号：US14345277

申请日：2011-10-27

Applicant: Ansoon Kim ,  Zhiyong Li ,  Wei Wu

Inventor： Ansoon Kim ,  Zhiyong Li ,  Wei Wu

IPC: G01J3/44 ,  G01N21/05 ,  G01N21/65 ,  G01N21/552 ,  G01N33/49 ,  G01N1/40 ,  B82Y20/00

CPC classification number: G01N21/05 ,  B82Y20/00 ,  G01N21/554 ,  G01N21/658 ,  G01N33/491 ,  G01N2001/4088 ,  G01N2021/651

Abstract: An apparatus for filtering species in a fluid includes a body having a first side and a second side, a first set of nano-fingers positioned on the body near the first side, a second set of nano-fingers positioned on the body closer to the second side than the first set of nano-fingers, wherein the nano-fingers in the second set of nano-fingers are arranged on the body at a relatively more densely than the nano-fingers in the first set of nano-fingers, and a cover positioned over the first set of nano-fingers and the second set of nano-fingers to form a channel with the body within which the first and second sets of nano-fingers are positioned.

公开(公告)号：US09588048B2

公开(公告)日：2017-03-07

申请号：US14118801

申请日：2011-05-20

Applicant: Ansoon Kim ,  Zhiyong Li

Inventor： Ansoon Kim ,  Zhiyong Li

IPC: G01N21/65 ,  G01J3/44 ,  B82Y15/00

CPC classification number: G01N21/658 ,  B82Y15/00 ,  G01J3/44

Abstract: A surface enhanced Raman spectroscopy (SERS) sensor, system and method employ nanorods and independent nanoparticles that interact. The sensor includes at least two spaced apart nanorods attached at first ends to a substrate and an independent nanoparticle. Second ends of the nanorods are movable into close proximity to one another and include a Raman active surface. The nanoparticle has a functionalized surface that includes a Raman signal generator. An interaction between the nanoparticle and the nanorod second ends in close proximity is detectable. The system includes the SERS sensor, an illumination source and a Raman signal detector. The method includes illuminating the interaction of the nanoparticle and the nanorods with an analyte, and detecting an effect on a Raman signal caused by the analyte.

Abstract translation: 表面增强拉曼光谱（SERS）传感器，系统和方法采用纳米棒和独立纳米粒子相互作用。 传感器包括至少两个间隔开的纳米棒，其在第一端附着到基底和独立的纳米颗粒。 纳米棒的第二端可以彼此靠近移动并且包括拉曼活性表面。 纳米颗粒具有包括拉曼信号发生器的官能化表面。 纳米颗粒和纳米棒第二末端之间的相互作用是可以接近的。 该系统包括SERS传感器，照明源和拉曼信号检测器。 该方法包括用分析物照射纳米颗粒和纳米棒的相互作用，并检测由分析物引起的对拉曼信号的影响。