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公开(公告)号：US20130216480A1
公开(公告)日：2013-08-22
申请号：US13610150
申请日：2012-09-11
Applicant: Clark K. Colton , Arthur Watterson , Rajesh Kumar , Virinder S. Parmar , Robert Fisher , Jayant Kumar
Inventor： Clark K. Colton , Arthur Watterson , Rajesh Kumar , Virinder S. Parmar , Robert Fisher , Jayant Kumar
IPC: A61K49/12 , G01N33/574 , G01N33/50 , A61K51/06
CPC classification number: A61K49/126 , A61K9/51 , A61K31/785 , A61K38/10 , A61K47/593 , A61K47/60 , A61K47/6907 , A61K49/0002 , A61K49/0032 , A61K49/0041 , A61K49/0043 , A61K49/0054 , A61K49/0056 , A61K49/0082 , A61K49/14 , A61K49/1809 , A61K49/1818 , A61K51/06 , A61K51/1237 , B82Y5/00 , C08G63/668 , C08G63/672 , C08G63/6826 , C08G63/6854 , C08G63/914 , C08G69/40 , C08G73/028 , C08G2261/126 , C08L77/00 , C08L79/02 , G01N33/5091 , G01N33/57492
Abstract: The present invention relates to amphiphilic polymers, and micelles and compositions comprising the same, and their use in a variety of biological settings, including imaging, targeting drugs, or a combination thereof for diagnostic and therapeutic purposes.
Abstract translation: 本发明涉及两亲性聚合物，以及包含该两性聚合物的胶束和组合物，以及它们在各种生物学设置中的用途，包括成像，靶向药物或其组合用于诊断和治疗目的。
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公开(公告)号：US08461105B2
公开(公告)日：2013-06-11
申请号：US12585574
申请日：2009-09-17
Applicant: Steven G. Wright , Troy Christensen , Thean Yeoh , Michael E. Rickey , Joyce M. Hotz , Rajesh Kumar , Henry R. Costantino
Inventor： Steven G. Wright , Troy Christensen , Thean Yeoh , Michael E. Rickey , Joyce M. Hotz , Rajesh Kumar , Henry R. Costantino
CPC classification number: A61K47/34 , A61K9/0024 , A61K9/1623 , A61K9/1647 , A61K9/1694 , A61K38/2278 , A61K38/26 , A61K47/26 , A61K47/38
Abstract: This invention relates to compositions for the sustained release of biologically active polypeptides, and methods of forming and using said compositions, for the sustained release of biologically active polypeptides. The sustained release compositions of this invention comprise a biocompatible polymer having dispersed therein, a biologically active polypeptide and a sugar.
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公开(公告)号：US08431685B2
公开(公告)日：2013-04-30
申请号：US12713036
申请日：2010-02-25
Applicant: Steven G. Wright , Troy Christensen , Thean Yeoh , Michael E. Rickey , Joyce M. Hotz , Rajesh Kumar , Henry R. Costantino
Inventor： Steven G. Wright , Troy Christensen , Thean Yeoh , Michael E. Rickey , Joyce M. Hotz , Rajesh Kumar , Henry R. Costantino
CPC classification number: A61K47/34 , A61K9/0024 , A61K9/1623 , A61K9/1647 , A61K9/1694 , A61K38/2278 , A61K38/26 , A61K47/26 , A61K47/38
Abstract: This invention relates to compositions for the sustained release of biologically active polypeptides, and methods of forming and using said compositions, for the sustained release of biologically active polypeptides. The sustained release compositions of this invention comprise a biocompatible polymer having dispersed therein, a biologically active polypeptide and a sugar.
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公开(公告)号：US08349991B2
公开(公告)日：2013-01-08
申请号：US11405012
申请日：2006-04-17
Applicant: Clark K. Colton , Arthur Watterson , Rajesh Kumar , Virinder S. Parmar , Robert Fisher , Jayant Kumar
Inventor： Clark K. Colton , Arthur Watterson , Rajesh Kumar , Virinder S. Parmar , Robert Fisher , Jayant Kumar
CPC classification number: A61K49/126 , A61K9/51 , A61K31/785 , A61K38/10 , A61K47/593 , A61K47/60 , A61K47/6907 , A61K49/0002 , A61K49/0032 , A61K49/0041 , A61K49/0043 , A61K49/0054 , A61K49/0056 , A61K49/0082 , A61K49/14 , A61K49/1809 , A61K49/1818 , A61K51/06 , A61K51/1237 , B82Y5/00 , C08G63/668 , C08G63/672 , C08G63/6826 , C08G63/6854 , C08G63/914 , C08G69/40 , C08G73/028 , C08G2261/126 , C08L77/00 , C08L79/02 , G01N33/5091 , G01N33/57492
Abstract: The present invention relates to amphiphilic polymers, and micelles and compositions comprising the same, and their use in a variety of biological settings, including imaging, targeting drugs, or a combination thereof for diagnostic and therapeutic purposes.
Abstract translation: 本发明涉及两亲性聚合物，以及包含该两性聚合物的胶束和组合物，以及它们在各种生物学设置中的用途，包括成像，靶向药物或其组合用于诊断和治疗目的。
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215.发明申请公开(公告)号：US20120316421A1
公开(公告)日：2012-12-13
申请号：US13382855
申请日：2010-07-07
Applicant: Rajesh Kumar , Themistocles Dassopoulos , Hani Girgis , Gregory Hager
Inventor： Rajesh Kumar , Themistocles Dassopoulos , Hani Girgis , Gregory Hager
CPC classification number: A61B1/041 , A61B1/00009 , G06T7/0012 , G06T2207/10016 , G06T2207/10068 , G06T2207/30032
Abstract: A system and method for automated image analysis which may enhance, for example, capsule endoscopy diagnosis. The system and methods may reduce the time required for diagnosis, and also help improve diagnostic consistency using an interactive feedback tool. Furthermore, the system and methods may be applicable to any procedure where efficient and accurate visual assessment of a large set of images is required.
Abstract translation: 用于自动图像分析的系统和方法，其可以增强例如胶囊内窥镜诊断。 系统和方法可以减少诊断所需的时间，并且还可以使用交互式反馈工具来帮助提高诊断一致性。 此外，该系统和方法可以适用于需要对大量图像进行高效和准确的视觉评估的任何程序。
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Patent Agency Ranking
公开(公告)号：US08308975B2
公开(公告)日：2012-11-13
申请号：US13280645
申请日：2011-10-25
Applicant: Yeonsuk Roh , Rajesh Kumar , Cheng-Le Zhao , David Kaczan , Theodore Michael Smiecinski
Inventor： Yeonsuk Roh , Rajesh Kumar , Cheng-Le Zhao , David Kaczan , Theodore Michael Smiecinski
IPC: C07D303/02
CPC classification number: C08G18/7621 , C08G18/36 , C08G18/4081 , C08G18/4829 , C08G18/64 , C08G2101/0008 , C08G2101/0083 , C08L83/00 , C11C3/006
Abstract: A polyol includes the reaction product of an epoxidized oil and an organic acid. The epoxidized oil and the organic acid are reacted in the presence of a Lewis base catalyst including at least one of a phosphorous atom or a nitrogen atom. The polyol is formed by a method that includes the step of reacting the epoxidized oil with the organic acid in the presence of the Lewis base catalyst.
Abstract translation: 多元醇包括环氧化油和有机酸的反应产物。 在包含磷原子或氮原子中的至少一种的路易斯碱催化剂的存在下使环氧化油和有机酸反应。 通过包含在路易斯碱催化剂存在下使环氧化油与有机酸反应的步骤的方法形成多元醇。
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217.发明授权Poly(lactide-co-glycolide) based sustained release microcapsules comprising a polypeptide and a sugar 有权包含多肽和糖的聚（丙交酯 - 共 - 乙交酯）基持续释放微胶囊公开(公告)号：US08293871B2
公开(公告)日：2012-10-23
申请号：US11578712
申请日：2005-04-15
Applicant: Steven G. Wright , Troy Christensen , Thean Yeoh , Michael E. Rickey , Joyce M. Hotz , Rajesh Kumar , Henry R. Costantino , Christine Smith , David M. Lokensgard , Mark Fineman , John Ong
Inventor： Steven G. Wright , Troy Christensen , Thean Yeoh , Michael E. Rickey , Joyce M. Hotz , Rajesh Kumar , Henry R. Costantino , Christine Smith , David M. Lokensgard , Mark Fineman , John Ong
IPC: A61K38/00
CPC classification number: A61K47/34 , A61K9/0024 , A61K9/1623 , A61K9/1647 , A61K9/1694 , A61K38/2278 , A61K38/26 , A61K47/26 , A61K47/38
Abstract: This invention relates to compositions for the sustained release of biologically active polypeptides, and methods of forming and using said compositions, for the sustained release of biologically active polypeptides. The sustained release compositions of this invention comprise a biocompatible polymer having dispersed therein, a biologically active polypeptide and a sugar.
Abstract translation: 本发明涉及用于持续释放生物活性多肽的组合物，以及形成和使用所述组合物用于持续释放生物活性多肽的方法。 本发明的缓释组合物包含分散在其中的生物相容性聚合物，生物活性多肽和糖。
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218.发明申请Novel Macromolecular Antioxidants Comprising Differing Antioxidant Moieties: Structures, Methods of Making and Using The Same 有权包含不同抗氧化成分的新型大分子抗氧化剂：结构，制备和使用它的方法公开(公告)号：US20120123145A1
公开(公告)日：2012-05-17
申请号：US13252576
申请日：2011-10-04
Applicant: Ashok L. Cholli , Rajesh Kumar
Inventor： Ashok L. Cholli , Rajesh Kumar
IPC: C07C229/42 , C07C215/80 , C07C233/29 , C07C237/20
CPC classification number: C07C231/12 , C07C235/34 , C07C235/38 , C08K5/005 , C08K5/13 , C08K5/132 , C08L21/00 , C09K15/00 , C09K15/08 , C09K15/22 , C09K15/24
Abstract: Described are antioxidant macromolecules and methods of making and using same.
Abstract translation: 描述了抗氧化剂大分子及其制备和使用方法。
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公开(公告)号：US20110297383A1
公开(公告)日：2011-12-08
申请号：US13126905
申请日：2009-10-29
Applicant: Christopher M. Tanguay , John Erickson , Victoria Manea , Jyh-Chiarng Huarng , Rajesh Kumar , Fikri Emrah Alemdaroglu
Inventor： Christopher M. Tanguay , John Erickson , Victoria Manea , Jyh-Chiarng Huarng , Rajesh Kumar , Fikri Emrah Alemdaroglu
Abstract: A proppant comprises a particle and a polycarbodiimide coating disposed on the particle. The polycarbodiimide coating comprises the reaction product of a polymeric isocyanate and a monomeric isocyanate, in the presence of a catalyst. A method of forming the proppant comprises the steps of providing the particle, providing the polymeric isocyanate, providing the monomeric isocyanate, providing the catalyst, reacting the polymeric isocyanate and the monomeric isocyanate in the presence of the catalyst to form the polycarbodiimide coating, and coating the particle with the polycarbodiimide coating.
Abstract translation: 支撑剂包括颗粒和设置在颗粒上的聚碳二亚胺涂层。 聚碳化二亚胺涂层包括聚合异氰酸酯和单体异氰酸酯在催化剂存在下的反应产物。 形成支撑剂的方法包括提供颗粒，提供聚合异氰酸酯，提供单体异氰酸酯，提供催化剂，在催化剂存在下使聚合异氰酸酯和单体异氰酸酯反应形成聚碳二亚胺涂层和涂层 具有聚碳化二亚胺涂层的颗粒。
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220.发明申请Macromolecular Antioxidants Based on Sterically Hindered Phenols and Phosphites 有权基于受阻酚和亚磷酸酯的大分子抗氧化剂公开(公告)号：US20110282098A1
公开(公告)日：2011-11-17
申请号：US13109800
申请日：2011-05-17
Applicant: Ashok L. Cholli , Rajesh Kumar
Inventor： Ashok L. Cholli , Rajesh Kumar
IPC: C07F9/22
CPC classification number: C09K15/322 , C07C231/02 , C08G61/00 , C08G61/10 , C08G2261/1422 , C08G2261/1426 , C08G2261/1432 , C08K5/04 , C08K5/20 , C08K5/52 , C08K13/02 , C07C235/38
Abstract: Sterically hindered phenol and phosphite based compounds, represented by a formula selected from I-III: and their use as antioxidants in a wide range of materials including, but not limited to, food, plastics, elastomers, composites and petroleum based products is disclosed herein.
Abstract translation: 由选自I-III的式表示的受阻酚和亚磷酸酯基化合物及其作为抗氧化剂在广泛范围的材料中的用途，包括但不限于食品，塑料，弹性体，复合材料和石油基产品。 。
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