公开(公告)号：US20190320954A1

公开(公告)日：2019-10-24

申请号：US16457692

申请日：2019-06-28

Applicant: DexCom, Inc.

Inventor： Jack Pryor ,  Apurv Ullas Kamath ,  Paul V. Goode, JR. ,  James H. Brauker

IPC: A61B5/145 ,  A61B5/00 ,  A61B5/1486 ,  A61B5/1495 ,  A61B5/1473

Abstract: Systems and methods for processing sensor analyte data are disclosed, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. The sensor can be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. Reference data resulting from benchtop testing an analyte sensor prior to its insertion can be used to provide initial calibration of the sensor data. Reference data from a short term continuous analyte sensor implanted in a user can be used to initially calibrate or update sensor data from a long term continuous analyte sensor.

公开(公告)号：US20190298922A1

公开(公告)日：2019-10-03

申请号：US16445055

申请日：2019-06-18

Applicant: DexCom, Inc.

Inventor： Naresh C. Bhavaraju ,  Arturo Garcia ,  Phil Mayou ,  Thomas A. Peyser ,  Apurv Ullas Kamath ,  Aarthi Mahalingam ,  Kevin Sayer ,  Thomas Hall ,  Michael Robert Mensinger ,  Hari Hampapuram ,  David Price ,  Jorge Valdes ,  Murrad Kazalbash

IPC: A61M5/172 ,  G16H50/30 ,  A61M5/142 ,  G01N33/49 ,  G16H40/63

Abstract: Methods and apparatus, including computer program products, are provided for processing analyte data. In some example implementations, a method may include generating glucose sensor data indicative of a host's glucose concentration using a glucose sensor; calculating a glycemic variability index (GVI) value based on the glucose sensor data; and providing output to a user responsive to the calculated glycemic variability index value. The GVI may be a ratio of a length of a line representative of the sensor data and an ideal length of the line. Related systems, methods, and articles of manufacture are also disclosed.

公开(公告)号：US20190251456A1

公开(公告)日：2019-08-15

申请号：US16269531

申请日：2019-02-06

Applicant: DexCom, Inc.

Inventor： Alexandra Elena Constantin ,  Scott M. Belliveau ,  Naresh C. Bhavaraju ,  Jennifer Blackwell ,  Eric Cohen ,  Basab Dattaray ,  Anna Leigh Davis ,  Rian Draeger ,  Arturo Garcia ,  John Michael Gray ,  Hari Hampapuram ,  Nathaniel David Heintzmann ,  Lauren Hruby Jepson ,  Matthew Lawrence Johnson ,  Apurv Ullas Kamath ,  Katherine Yerre Koehler ,  Phil Mayou ,  Patrick Wile McBride ,  Michael Robert Mensinger ,  Sumitaka Mikami ,  Andrew Attila Pal ,  Nicholas Polytaridis ,  Philip Thomas Pupa ,  Eli Reihman ,  Peter C. Simpson ,  Tomas C. Walker ,  Daniel Justin Wiedeback ,  Subrai Girish Pai ,  Matthew T. Vogel

IPC: G06N5/04 ,  G16H50/20

CPC classification number: G16H70/20 ,  A61B5/0022 ,  A61B5/1118 ,  A61B5/14532 ,  A61B5/4839 ,  A61B5/486 ,  A61B5/4866 ,  A61B5/7275 ,  A61B5/7282 ,  A61B5/746 ,  G06N5/045 ,  G06N20/00 ,  G16H50/20

Abstract: Systems and methods are provided to determine a time to provide guidance to a user regarding management of a physiologic condition such as diabetes. The determination may be based upon a model or pattern. The time to deliver guidance may be calculated to be useful to a user in the management of a glucose concentration level.

公开(公告)号：US20190246973A1

公开(公告)日：2019-08-15

申请号：US16269480

申请日：2019-02-06

Applicant: DexCom, Inc.

Inventor： Alexandra Elena Constantin ,  Scott M. Belliveau ,  Naresh C. Bhavaraju ,  Jennifer Blackwell ,  Eric Cohen ,  Basab Dattaray ,  Anna Leigh Davis ,  Rian Draeger ,  Arturo Garcia ,  John Michael Gray ,  Hari Hampapuram ,  Nathaniel David Heintzmann ,  Lauren Hruby Jepson ,  Matthew Lawrence Johnson ,  Apurv Ullas Kamath ,  Katherine Yerre Koehler ,  Phil Mayou ,  Patrick Wile McBride ,  Michael Robert Mensinger ,  Sumitaka Mikami ,  Andrew Attila Pal ,  Nicholas Polytaridis ,  Philip Thomas Pupa ,  Eli Reihman ,  Peter C. Simpson ,  Tomas C. Walker ,  Daniel Justin Wiedeback ,  Subrai Girish Pai ,  Matthew T. Vogel

IPC: A61B5/00 ,  A61B5/145 ,  A61B5/11

CPC classification number: G16H70/20 ,  A61B5/0022 ,  A61B5/1118 ,  A61B5/14532 ,  A61B5/4839 ,  A61B5/486 ,  A61B5/4866 ,  A61B5/7275 ,  A61B5/7282 ,  A61B5/746 ,  G06N5/045 ,  G06N20/00 ,  G16H50/20

Abstract: Systems and methods are provided to provide guidance to a user regarding management of a physiologic condition such as diabetes. The determination may be based upon a patient glucose concentration level. The glucose concentration level may be provided to a stored model to determine a state. The guidance may be determined based at least in part on the determined state.

公开(公告)号：US10349873B2

公开(公告)日：2019-07-16

申请号：US15140307

申请日：2016-04-27

Applicant: DexCom, Inc.

Inventor： Apurv Ullas Kamath ,  Jacob S. Leach ,  Ying Li ,  Daiting Rong ,  Sean Saint ,  Peter C. Simpson ,  Mark C. Brister

IPC: A61B5/00 ,  A61B5/145 ,  A61B5/1486 ,  A61B5/1495 ,  C12Q1/00 ,  A61B5/1473 ,  A61M5/14 ,  A61M5/168 ,  A61M25/00 ,  G06F19/00 ,  G16H40/40

Abstract: Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into communication with a host's circulatory system.

公开(公告)号：US20190209095A1

公开(公告)日：2019-07-11

申请号：US16356599

申请日：2019-03-18

Applicant: DexCom, Inc.

Inventor： Apurv Ullas Kamath ,  James H. Brauker ,  Aarthi Mahalingam ,  Ying Li

IPC: A61B5/00 ,  A61B5/145 ,  A61B5/1486 ,  A61B5/01

CPC classification number: A61B5/7203 ,  A61B5/01 ,  A61B5/145 ,  A61B5/14532 ,  A61B5/14539 ,  A61B5/14542 ,  A61B5/14865 ,  A61B5/6848 ,  A61B5/7225 ,  A61B5/7239 ,  A61B5/7257 ,  A61B5/726 ,  A61B5/742 ,  A61B2560/0252 ,  Y02A90/22 ,  Y02A90/26

Abstract: Systems and methods for minimizing or eliminating transient non-glucose related signal noise due to non-glucose rate limiting phenomenon such as interfering species, ischemia, pH changes, temperatures changes, known or unknown sources of mechanical, electrical and/or biochemical noise, and the like. The system monitors a data stream from a glucose sensor and detects signal artifacts that have higher amplitude than electronic or diffusion-related system noise. The system processes some or the entire data stream continually or intermittently based at least in part on whether the signal artifact event has occurred.

公开(公告)号：US20190110724A1

公开(公告)日：2019-04-18

申请号：US16222804

申请日：2018-12-17

Applicant: DexCom, Inc.

Inventor： Apurv Ullas Kamath ,  Peter C. Simpson ,  James H. Brauker ,  Paul V. Goode, JR.

IPC: A61B5/1486 ,  A61B5/00 ,  A61B5/1495 ,  A61B5/145

Abstract: Disclosed herein are systems and methods for calibrating a continuous analyte sensor, such as a continuous glucose sensor. One such system utilizes one or more electrodes to measure an additional analyte. Such measurements may provide a baseline or sensitivity measurement for use in calibrating the sensor. Furthermore, baseline and/or sensitivity measurements may be used to trigger events such as digital filtering of data or suspending display of data.

公开(公告)号：US20190090789A1

公开(公告)日：2019-03-28

申请号：US16202984

申请日：2018-11-28

Applicant: DexCom, Inc.

Inventor： Apurv Ullas Kamath ,  John Michael Dobbles ,  Aarthi Mahalingam

IPC: A61B5/1477 ,  A61B5/00 ,  A61B5/1495 ,  A61B5/145 ,  A61B5/1486

Abstract: Systems and methods for processing sensor data are provided. In some embodiments, systems and methods are provided for calibration of a continuous analyte sensor. In some embodiments, systems and methods are provided for classification of a level of noise on a sensor signal. In some embodiments, systems and methods are provided for determining a rate of change for analyte concentration based on a continuous sensor signal. In some embodiments, systems and methods for alerting or alarming a patient based on prediction of glucose concentration are provided.

公开(公告)号：US10238323B2

公开(公告)日：2019-03-26

申请号：US14717904

申请日：2015-05-20

Applicant: DexCom, Inc.

Inventor： Stephen J. Vanslyke ,  Naresh C. Bhavaraju ,  Sebastian Böhm ,  Leif N. Bowman ,  Michael J. Estes ,  Arturo Garcia ,  Apurv Ullas Kamath ,  Andrew Attila Pal ,  Thomas A. Peyser ,  Anna Leigh Rack-Gomer ,  Daiting Rong ,  Disha B. Sheth ,  Peter C. Simpson ,  Dmytro Sokolovsky

IPC: A61B5/00 ,  A61B5/1495 ,  A61B5/01 ,  A61B5/11 ,  A61B5/053 ,  A61B5/145 ,  A61B5/1486 ,  A61B5/1473 ,  A61M5/172 ,  G06F19/00

Abstract: Systems and methods disclosed here provide ways to discriminate fault types encountered in analyte sensors and systems and further provide ways to process such discriminated faults responsively based on sensor data, clinical context information, and other data about the patient or patient's environment. The systems and methods thus employ clinical context in detecting and/or responding to errors or faults associated with an analyte sensor system, and discriminating the type of fault, and its root cause, particularly as fault dynamics can appear similar to the dynamics of physiological systems, emphasizing the importance of discriminating the fault and providing appropriate responsive processing. Thus, the disclosed systems and methods consider the context of the patient's health condition or state in determining how to respond to the fault.

公开(公告)号：US20190059826A1

公开(公告)日：2019-02-28

申请号：US16172550

申请日：2018-10-26

Applicant: DexCom, Inc.

Inventor： Hari Hampapuram ,  Anna Leigh Davis ,  Naresh Bhavaraju ,  Apurv Ullas Kamath ,  Claudio Cobelli ,  Giovanni Sparacino ,  Andrea Facchinetti ,  Chiara Zecchin

IPC: A61B5/00 ,  G06F19/00 ,  A61B5/145

CPC classification number: A61B5/746 ,  A61B5/0004 ,  A61B5/002 ,  A61B5/0022 ,  A61B5/0031 ,  A61B5/14503 ,  A61B5/14532 ,  A61B5/4848 ,  A61B5/4866 ,  A61B5/7221 ,  A61B5/7275 ,  G06F19/00

Abstract: Systems and methods for providing sensitive and specific alarms indicative of glycemic condition are provided herein. In an embodiment, a method of processing sensor data by a continuous analyte sensor includes: evaluating sensor data using a first function to determine whether a real time glucose value meets a first threshold; evaluating sensor data using a second function to determine whether a predicted glucose value meets a second threshold; activating a hypoglycemic indicator if either the first threshold is met or if the second threshold is predicted to be met; and providing an output based on the activated hypoglycemic indicator.