Abstract:
Provided is an antiviral agent against animal viruses. The antiviral agent contains a protein or a nucleic acid sequence encoding the protein, as an active ingredient, the protein having binding ability and degrading ability to foreign nucleic acid chains invaded in an animal cell and that has no cytotoxicity to the animal cell itself. Also provided is an antiviral animal cell containing the protein according to the present invention, or the nucleic acid sequence encoding the protein. The antiviral agent and antiviral animal cell exhibit advantageous effects in that they selectively degrade foreign nucleic acid chains invaded in an animal cell and have no cytotoxicity to the animal cell, thus causing no death of the animal cell.
Abstract:
In a variability modeling method implemented in a computer system to implement a self-adaptive system, the variability modeling method includes building ontology in which a target system to be modeled is defined through requirement analysis of the target system, deciding whether adaptation is required by continuously monitoring the target system and a change in environment, and when it is decided that the adaptation is required, performing reconfiguration of the target system by determining the variable point suitable for a change in context.
Abstract:
Disclosed is a method of providing a disease co-occurrence probability including (a) receiving a disease network in which respective diseases are shown as nodes and a correlation between diseases is shown as an edge between the nodes and (b) calculating, when at least one disease is given, a probability of an occurrence of another disease in addition to the given disease, the corresponding disease which accompanies the given disease, from the disease network.
Abstract:
The present invention relates to methods of preventing or treating skin necroptosis diseases, including administering to subjects receptor-interacting protein kinase-3 (RIP3)-mixed lineage kinase domain-like protein (MLKL) pathway blockers or dabrafenib, and method of diagnosing of skin necroptosis diseases, including detecting phosphorylated MLKL. The RIP3-MLKL pathway blockers according to the present invention directly suppress RIP3 overexpressing in skin necroptosis diseases, or inhibit phosphorylation and translocation to plasma membranes of MLKL, subsequently induced therefrom, thereby effectively preventing skin cell death via necroptosis. Thus, the present invention can prevent or treat a variety of skin diseases caused by necroptosis.
Abstract:
Disclosed is a high efficiency video coding (HEVC) encoding device including a candidate group updater configured to select a plurality of representative modes as a candidate group from among intra-prediction modes and update the candidate group using a plurality of minimum modes selected from the candidate group, the plurality of representative modes each representing a range where there is an optimal mode, and an optimal mode selector configured to select any one mode as an optimal mode from among a plurality of minimum modes selected from the updated candidate group.
Abstract:
A node device using a TV white space (TVWS) includes a decision unit for comparing energy levels of a first sub-channel and at least one second sub-channel adjacent to the first sub-channel among a plurality of sub-channels with respect to a digital TV (DTV) channel including the plurality of sub-channels and deciding whether the DTV channel is an available channel, and a discovery unit for, if the DTV channel is decided as the available channel, discovering a beacon by scanning the first sub-channel in the DTV channel.
Abstract:
The present disclosure relates to a polyvinyl copolymer in which one or more side-chain sulfonic acids are attached on the hydroxy group of polyvinyl alcohol or a polyvinyl phenol and a preparation method thereof, a dopant including the same, a conductive polymer composite including the dopant with a conductive polymer and a preparation method thereof, wherein the electrical conductivity, dispersibility, solubility, heat-resistance and environment-resistance of the conductive polymer composite can be enhanced by using the dopant including the copolymer.
Abstract:
A hydrogen sensor and a method for manufacturing the same are provided. The hydrogen sensor includes a metal oxide layer formed over a substrate, and a catalytic pattern that is formed over the metal oxide layer. Further, a protective layer is formed over the catalytic pattern.
Abstract:
A hollow-core structure including: an inner mold that has a hollow cylindrical shell shape; an outer mold that has a hollow cylindrical shell shape to correspond to the inner mold, and in which the inner mold is disposed to be separated; and a filling member that is filled in a separation space between the inner mold and the outer mold.
Abstract:
The present invention relates to a biomarker composition for detecting white matter stroke, the biomarker composition containing a toll-like receptor 2 (TLR2), and a medical use using the TLR2. The TLR2 can be used as a biomarker for white matter stroke by defending against ischemic demyelination and oligodendrocyte death, and when targeting the TLR2, ischemic white matter stroke can be treated or prevented.