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21.发明授权Fluid delivery system including a reusable flow path and a per-patient disposable fluid path 失效流体递送系统包括可重复使用的流动路径和每个患者的一次性流体路径公开(公告)号：US06731971B2
公开(公告)日：2004-05-04
申请号：US10095127
申请日：2002-03-11
IPC分类号： A61M500
CPC分类号： A61M5/16827 , A61M5/007 , A61M2205/6072 , G06F19/00 , Y10S128/12 , Y10S128/13
摘要： An apparatus and method enabling the injection of fluid media into a plurality of patients is provided, including a fluid supply source providing multiple doses, a metering device for measuring the doses, a pressurizing device to effect injection, a contamination prevention device disposed between the fluid source and the patient and, when desired, an electronic control device to integrate operation of the apparatus and process.
摘要翻译： 提供了一种能够将流体介质注入多个患者的装置和方法，包括提供多个剂量的流体供应源，用于测量剂量的计量装置，实现注射的加压装置，设置在流体之间的防污染装置 源和患者，并且当需要时，电子控制装置以集成装置和过程的操作。
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公开(公告)号：US06397098B1
公开(公告)日：2002-05-28
申请号：US09300326
申请日：1999-04-27
申请人： Arthur E. Uber, III , Edward J. Rhinehart , Rosemary Almon-Martin , David M. Griffiths , Alan D. Hirschman , Francis J. Sciulli , Walter Grumski , Vera Pagano , Karen Zelenski
发明人： Arthur E. Uber, III , Edward J. Rhinehart , Rosemary Almon-Martin , David M. Griffiths , Alan D. Hirschman , Francis J. Sciulli , Walter Grumski , Vera Pagano , Karen Zelenski
IPC分类号： A61B600
CPC分类号： A61B8/481 , A61B6/481 , A61B6/504 , A61B8/06 , A61M5/007 , A61M5/14546 , A61M5/1723 , A61M2205/581 , A61M2205/80 , G06F19/00 , G06F19/321 , G06F19/3468
摘要： A system for producing a contrast-enhanced medical image of a patient includes a source of a contrast or enhancement medium, a pressurizing unit in fluid connection with the source of contrast or enhancement medium, an energy source operable to apply energy to a region of the patient, an imaging unit providing a visual display of an internal view of the patient based upon a signal resulting from the energy applied to the region of the patient, and a control unit. In an embodiment, the signal is affected by a condition of the contrast or enhancement medium in the patient. To control the procedures, the control unit adjusts the condition of the contrast or enhancement medium in the patient based upon the signal. A communication interface preferably enables information between an injector subsystem and an imaging subsystem.
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公开(公告)号：US06375624B1
公开(公告)日：2002-04-23
申请号：US09398658
申请日：1999-09-17
IPC分类号： A61B500
CPC分类号： A61M5/16836 , Y10S128/13
摘要： A microwave antenna senses the temperature of tissue into which a fluid is to be injected. The fluid is injected by a needle or other vascular entry device connected to a fluid injector by a connector tube. The fluid temperature is measured by a temperature sensor attached to the connector tube. An alarm processor determines whether an extravasation occurs by comparing a temperature discrimination function derived from tissue temperature taken at different times with a calculated threshold value. The threshold value is calculated from the tissue temperature and the fluid temperature. The threshold value is recalculated and updated continuously during the fluid injection.
摘要翻译： 微波天线检测要注入流体的组织的温度。 流体由连接管连接到流体注射器的针或其它血管进入装置注射。 流体温度由安装在连接管上的温度传感器测量。 报警处理器通过将从不同时间获得的组织温度导出的温度鉴别功能与计算的阈值进行比较来确定是否发生外渗。 阈值由组织温度和流体温度计算。 在流体注入期间，阈值被重新计算和连续更新。
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公开(公告)号：US06353324B1
公开(公告)日：2002-03-05
申请号：US09435100
申请日：1999-11-05
IPC分类号： G01R2912
CPC分类号： G01R19/2509 , G01J1/44
摘要： The present invention relates to an electronic circuit and an array of such circuits for precisely measuring small amounts or small changes in the amount of charge, voltage, or electrical currents. One embodiment of the present invention provides an electronic circuit for measuring current or charge that can be used with a variety of sensing media (including high impedance sensing media) that produce a signal by either charge or current production or induction in response to physical phenomena occurring within the sensing media. In another embodiment, the voltage level (bias) of either the sensing or reference electrode can be switched relative to the other upon receipt of a triggering pulse. This changes the polarity of the electric field to cause charge of the opposite polarity to be driven to the sensing electrode, thereby eliminating the need to electrically connect a discharge path to the sensing electrode to clear the charge accumulated at the sensing electrode. This can be supplemented by capacitively coupling a compensation signal to the sensing electrode to cause the amplifier output signal to lessen in magnitude below a threshold level that permits additional charge or current measurements of the same polarity before performing bias reversal. Alternately or in combination with bias reversal and capacitive compensation, sensor performance can be improved by minimizing inaccuracies caused by leakage currents or current drawn from the sensor. Other described methods of reducing leakage currents that can be used alone or in combination with the aforementioned features include the use of guard rings, physical switches or relays, the controlled creation of charges or currents of a specific polarity in a specific region of the sensing medium, controlled leakage over the surface of an insulator, and controlling the environment in which the circuit operates.
摘要翻译： 本发明涉及用于精确测量电荷量，电压或电流量的少量或小变化的这种电路的电子电路和阵列。 本发明的一个实施例提供了一种用于测量电流或电荷的电子电路，其可以与各种感测介质（包括高阻抗感测介质）一起使用，所述传感介质（包括高阻抗传感介质）通过电荷或当前的产生或响应于物理现象产生的感应而产生信号 在传感媒体内。 在另一个实施例中，感测或参考电极的电压电平（偏置）可以在接收到触发脉冲时相对于另一个切换。 这改变了电场的极性，导致相反极性的电荷被驱动到感测电极，从而不需要将放电路径电连接到感测电极，以清除在感测电极处积累的电荷。 这可以通过将补偿信号电容耦合到感测电极来补充，以使放大器输出信号在低于允许进行偏置反转之前允许相同极性的额外电荷或电流测量的阈值电平之下降低。 或者与偏置反转和电容补偿相结合，可以通过最小化由漏电流或从传感器吸取的电流引起的不准确度来改善传感器性能。 减少可以单独使用或与上述特征组合使用的泄漏电流的其它描述的方法包括使用保护环，物理开关或继电器，在感测介质的特定区域中控制产生特定极性的电荷或电流 ，在绝缘体的表面上的受控泄漏，以及控制电路工作的环境。
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公开(公告)号：US5954668A
公开(公告)日：1999-09-21
申请号：US663710
申请日：1996-06-14
CPC分类号： A61M5/16836 , Y10S128/13
摘要： A microwave antenna senses the temperature of tissue into which a fluid is to be injected. The fluid is injected by a needle or other vascular entry device connected to a fluid injector by a connector tube. The fluid temperature is measured by a temperature sensor attached to the connector tube. An alarm processor determines whether an extravasation occurs by comparing a temperature discrimination function derived from tissue temperature taken at different times with a calculated threshold value. The threshold value is calculated from the tissue temperature and the fluid temperature. The threshold value is recalculated and updated continuously during the fluid injection.
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公开(公告)号：USRE35979E
公开(公告)日：1998-12-01
申请号：US804433
申请日：1991-12-10
CPC分类号： A61M5/007 , A61M5/14546 , A61M5/31511 , A61M5/14566 , A61M5/31515
摘要： An angiographic injector has an injector portion which includes a rotating turret for housing two angiographic syringes in readiness for injection. The injector further employs a driving mechanism for connecting with and controlling the movement of a syringe plunger once one of the syringes is in place for injection. Through the use of guide means on each syringe and corresponding alignment means on a pressure jacket, the syringe is alignably and securely mounted within the pressure jacket on the rotating turret. Each syringe plunger is releasably connected to the driving mechanism for an injection operation, and released from the driving mechanism when the injection operation has been completed, such that the driving mechanism can be withdrawn from the syringe relative to the plunger without drawing body fluid of a patient into the syringe. Various types of plunger release mechanisms for this purpose are disclosed. The questions raised in reexamination request No. 90/003,918 filed Aug. 7, 1995, have been considered and the results thereof are reflected in this reissue patent which constitutes the reexamination certificate required by 35 U.S.C. 307 as provided in 37 CFR 1.570(e).
摘要翻译： 血管造影注射器具有注射器部分，其包括用于容纳注射用的两个血管造影注射器的旋转转台。 一旦注射器在注射器就位之后，注射器还采用驱动机构来连接和控制注射器柱塞的移动。 通过使用每个注射器上的引导装置和压力套上的相应对准装置，注射器可对准地且牢固地安装在旋转转台上的压力套内。 每个注射器柱塞可释放地连接到用于注射操作的驱动机构，并且当注射操作已经完成时从驱动机构释放，使得驱动机构可以相对于柱塞从注射器中抽出而不抽出体液 病人进入注射器。 公开了用于此目的的各种类型的柱塞释放机构。 + RR已经考虑了1995年8月7日提交的第90 / 003,918号复审请求中提出的问题，其结果反映在构成35U.S.C.所要求的复审证书的该再发行专利中。 307如第37 CFR 1.570（e）条所规定。
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公开(公告)号：US5827219A
公开(公告)日：1998-10-27
申请号：US655886
申请日：1996-05-31
CPC分类号： A61M5/16827 , A61M5/007 , A61M5/142 , A61M5/16886 , A61M5/172 , A61M2205/12
摘要： The present invention provides a number of pumping systems and injection systems particularly useful for injecting a liquid medium into a patient. In general, the pumping systems comprise a removable pumping unit. The removable pumping unit includes means for pressurizing the liquid medium via the rotational displacement of the liquid medium. The present invention also provides a pumping system comprising a pumping unit for pressurizing the liquid medium and a feedback-controlled drive means in connection with the pumping unit for providing a controlled powered drive to the pumping unit. The pumping system further comprises a flow meter for measuring the flow rate of the pressurized liquid medium exiting the pumping system and control means in communicative connection with the drive means for providing a control signal to control the powered drive provided to the pumping unit. The control means is suitable to receive a feedback signal from the flow meter corresponding to the flow rate of the pressurized liquid medium exiting the pumping unit. The control signal provided to the drive means is a function of the feedback signal.
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公开(公告)号：US5739508A
公开(公告)日：1998-04-14
申请号：US729098
申请日：1996-10-11
申请人： Arthur E. Uber, III
发明人： Arthur E. Uber, III
CPC分类号： A61M5/172 , A61M2205/52 , A61M2205/6018
摘要： This invention relates generally to the field of medical devices for delivering medicinal fluids to patients during medical procedures and more particularly, this invention relates to improved medical fluid delivery systems and methods of use which incorporate a closed loop information path from the manufacturer to a product user such as a hospital or other medical institution and back to the original manufacturer. The information originally incorporated with the product is used by the consumer to aid in use of the product. The information which accompanies the product is updated and new information is added in order to provide the manufacturer with information on how the product is used.
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公开(公告)号：US5494036A
公开(公告)日：1996-02-27
申请号：US158055
申请日：1993-11-26
申请人： Arthur E. Uber, III , Seid Waddell , John Stulen , Jon E. Manley
发明人： Arthur E. Uber, III , Seid Waddell , John Stulen , Jon E. Manley
CPC分类号： G01R33/285 , A61M5/007 , A61M5/14546 , G01R33/28 , G01R33/281 , G01R33/283 , G01R33/421 , Y10S128/01
摘要： This invention relates generally to the field of Magnetic Resonance Imaging (MRI) systems for generating diagnostic images of a patient's internal organs and more particularly, this invention relates to improved MRI systems with decreased interference between the magnetic field used for producing diagnostic images and the magnetic fields generated by the electric motors used for driving the pistons of the contrast media injectors. Additionally, the system employs an improved communication link between an externally located system controller and the injection head control unit located within the electromagnetic isolation barrier which defines the magnetic imaging room.
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30.发明授权
公开(公告)号：US4804847A
公开(公告)日：1989-02-14
申请号：US7195
申请日：1987-01-27
申请人： Arthur E. Uber, III
发明人： Arthur E. Uber, III
摘要： The radiation detector includes tissue equivalent bubbles of plastic defining volumes of gas to be ionized by radiation. One or more integrated circuits (ICs) are disposed below the volumes of gas and a collecting electrode on the IC is in direct contact with the gas. Circuitry for generating an electric field within the volume of gas moves the ions therein to the collecting electrode. The collecting electrode is part of an amplifying circuit disposed within the IC. The output from the amplifier is representative of the collected ions and therefore representative of the radiation. The signal from the amplifier is send to an interface which conditions, buffers and stores the signal. The radiation dose and dose rate are computed in the interface. A communications section transfers that data from the radiation detector. A separate calibration and display unit calibrates the interface by controlling The conditioning of the signal. An area monitor and air monitor are further enhancements of the radiation detector.
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