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    Low protein binding membrane
    21.
    发明授权
    Low protein binding membrane 失效
    低蛋白结合膜

    公开(公告)号：US4921654A

    公开(公告)日：1990-05-01

    申请号：US408737

    申请日：1989-09-18

    Applicant: Chung-Jen Hou ,  James Disbrow ,  Kenneth C. Hou

    Inventor： Chung-Jen Hou ,  James Disbrow ,  Kenneth C. Hou

    IPC: B01D67/00

    CPC classification number: B01D67/0093 ,  B01D67/0011 ,  B01D2323/08 ,  B01D2323/12 ,  B01D2323/38 ,  B01D2323/385

    Abstract: A modified microporous membrane comprising an organic polymeric microporous membrane having microporous surfaces and having hydroxyl, mercapto, carboxyl, or amino functionality on the surfaces modified by a reactive modifying polymer having a polymer chain and having along the polymer chain epoxy or epithio functional groups capable of reacting with the functionality on the surface of the membrane and terminal neutral chemical functionality. The preferred reactive modifying polymer is made from a free radical polymerization of:(a) a polymerizable compound containing an epoxy or epithio group capable of direct covalent coupling to the surface functionalities of the microporous membrane and a vinyl group capable of free radical polymerization; and(b) ##STR1## wherein R.sub.1 is an alpha, beta ethylenically unsaturated polymerizable radical of two or three carbon atoms;R.sub.2 is an alkyl substituent of two to five carbon atoms having a terminal hydroxyl functionality or (R.sub.3 O).sub.n H,wherein R.sub.3 is an alkyl substituent of two or three carbon atoms and n is 1 to 20.The membranes have a relatively low-binding capacity for protein.

    Abstract translation: 一种改性微孔膜，其包含具有微孔表面并且具有羟基，巯基，羧基或氨基官能团的有机聚合物微孔膜，所述表面由具有聚合物链且具有聚合物链的反应性改性聚合物改性的表面具有环氧或环硫官能团 与膜表面的功能和末端中性化学官能团反应。 优选的反应性改性聚合物由以下的自由基聚合制成：（a）含有能够与微孔膜的表面官能团直接共价偶联的环氧基或环硫基的可聚合化合物和能够进行自由基聚合的乙烯基; 和（b）其中R1是两个或三个碳原子的α，β烯键式不饱和可聚合基团; R2是具有末端羟基官能度的二至五个碳原子的烷基取代基或（R3O）nH，其中R3是两个或三个碳原子的烷基取代基，n是1至20.该膜具有相对低的结合能力 用于蛋白质。

    Inter-penetrating network charge modified microporous membrane
    25.
    发明授权
    Inter-penetrating network charge modified microporous membrane 失效
    穿透网络电荷改性微孔膜

    公开(公告)号：US5531893A

    公开(公告)日：1996-07-02

    申请号：US160427

    申请日：1993-12-01

    Applicant: Hopin Hu ,  Chung-Jen Hou

    Inventor： Hopin Hu ,  Chung-Jen Hou

    IPC: B01D71/38 ,  B01D67/00 ,  B01D69/14 ,  B01D71/52 ,  B01D71/64 ,  B01D71/68 ,  C08G59/20 ,  C08G59/22 ,  C08L71/02 ,  C08L81/00 ,  C08L81/06

    CPC classification number: B01D71/68 ,  B01D67/0011 ,  B01D69/141 ,  B01D2323/30 ,  B01D2325/14 ,  B01D2325/36

    Abstract: Hydrophilic inter-penetrating network charge modified microporous membranes are provided as well as a method of preparing the membranes by casting a membrane matrix blend containing matrix polymer, a solvent system, a wetting polymer compatible with the matrix polymer, and a charge modified system which forms a cross-linked interpenetrating network structure within the microporous membrane substrate during the membrane fabrication process which network structure optionally can be locked in by heat curing. The membranes are useful for filtering ultrapure water with 18 megaohm-cm resistivity for the electronic industry, and they can also be used for the removal of a variety of contaminants from fluid media, such as very fine negatively charged particles, bacteria and endotoxins, with greatly enhanced filtration efficiency.

    Abstract translation: 提供亲水互穿网络电荷改性微孔膜，以及通过浇铸含有基质聚合物，溶剂系统，与基质聚合物相容的润湿聚合物的膜基质共混物和形成电荷的改进体系制备膜的方法 在膜制造过程中微孔膜基底内的交联互穿网络结构，该网络结构任选地可以通过热固化而被锁定。 该膜可用于过滤用于电子工业的18兆欧姆 - 厘米电阻率的超纯水，它们还可用于从流体介质中除去各种污染物，例如非常细的带负电荷的颗粒，细菌和内毒素，具有 大大提高了过滤效率。

    Inter-penetrating network charge modified microporous membrane
    26.
    发明授权
    Inter-penetrating network charge modified microporous membrane 失效
    穿透网络电荷改性微孔膜

    公开(公告)号：US5277812A

    公开(公告)日：1994-01-11

    申请号：US17036

    申请日：1993-02-12

    Applicant: Hopin Hu ,  Chung-Jen Hou

    Inventor： Hopin Hu ,  Chung-Jen Hou

    IPC: B01D67/00 ,  B01D69/14 ,  B01D71/68

    CPC classification number: B01D71/68 ,  B01D67/0011 ,  B01D69/141 ,  B01D2323/30 ,  B01D2325/14 ,  B01D2325/36

    Abstract: Hydrophilic inter-penetrating network charge modified microporous membranes are provided as well as a method of preparing the membranes by casting a membrane matrix blend containing matrix polymer, a solvent system, a wetting polymer compatible with the matrix polymer, and a charge modified system which forms a cross-linked inter-penetrating network structure within the microporous membrane substrate during the membrane fabrication process which network structure optionally can be locked in by heat curing. The membranes are useful for filtering ultra pure water with 18 megaohm-cm resistivity for the electronic industry, and they can also be used for the removal of a variety of contaminants from fluid media, such as very fine negatively charged particles, bacteria and endotoxins, with greatly enhanced filtration efficiency.

    Abstract translation: 提供亲水互穿网络电荷改性微孔膜，以及通过浇铸含有基质聚合物，溶剂系统，与基质聚合物相容的润湿聚合物的膜基质共混物和形成电荷的改进体系制备膜的方法 在膜制造过程中在微孔膜基底内的交联的穿透网络结构，其中该网络结构任选地可以通过热固化被锁定。 该膜可用于过滤用于电子工业的具有18兆欧姆 - 厘米电阻率的超纯水，并且它们还可用于从流体介质（例如非常细的带负电荷的颗粒，细菌和内毒素）中除去各种污染物， 大大提高了过滤效率。

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