公开(公告)号：US5458782A

公开(公告)日：1995-10-17

申请号：US178742

申请日：1994-01-07

Applicant: Kenneth C. Hou ,  James C. Disbrow ,  Ronald V. Repetti ,  C. Thomas Badenhop

Inventor： Kenneth C. Hou ,  James C. Disbrow ,  Ronald V. Repetti ,  C. Thomas Badenhop

IPC: B01D71/56

CPC classification number: B01D71/56

Abstract: A method for the production of a hydrolytically stable nylon membrane includes providing a nylon having at least about 0.9 moles of amino end groups per mole of nylon and preparing the nylon membrane therefrom. The membrane can be used in cartridges for use in filtration applications as may be necessary in the food and beverage industry as well as for the production of pharmaceuticals and the manufacture of electronic components. The membrane is capable of withstanding autoclaving and hot water sanitization without molecular dissociation regardless of its pore size, or thickness of the membrane, or the nylon solids content of the dope or, the temperature at which the dope is made.

Abstract translation: 制备水解稳定的尼龙膜的方法包括提供每摩尔尼龙具有至少约0.9摩尔氨基端基的尼龙并由其制备尼龙膜。 膜可以用于在食品和饮料工业中可能需要的过滤应用中使用的滤芯中，以及用于生产药物和电子部件的制造。 无论膜的孔径，膜的厚度，涂料的尼龙固体含量，涂料的温度如何，膜都能耐受高压灭菌和热水消毒而无需分子解离。

公开(公告)号：US4980067A

公开(公告)日：1990-12-25

申请号：US276831

申请日：1988-11-28

Applicant: Kenneth C. Hou ,  Chung-Jen Hou ,  Haunn-Lin Chen

Inventor： Kenneth C. Hou ,  Chung-Jen Hou ,  Haunn-Lin Chen

IPC: B01J20/28 ,  B01J20/32 ,  B01J39/22 ,  B01J41/16 ,  B01J47/12 ,  C08F251/00 ,  C08G81/02

CPC classification number: B01J20/28033 ,  B01J20/28052 ,  B01J20/2808 ,  B01J20/321 ,  B01J20/3212 ,  B01J20/3217 ,  B01J20/327 ,  B01J20/3272 ,  B01J20/3278 ,  B01J39/22 ,  B01J41/16 ,  B01J47/123 ,  C08F251/00 ,  C08G81/02

Abstract: A microporous membrane modified by coating or grafting thereon a polyionene material. The thus-modified microporous membrane is useful for separating microorganism-originated contaminants from biological liquids.

Abstract translation: 通过在其上涂覆或接枝聚苯乙烯材料而改性的微孔膜。 这样改性的微孔膜可用于从生物液体中分离微生物来源的污染物。

公开(公告)号：US4908137A

公开(公告)日：1990-03-13

申请号：US336164

申请日：1989-04-11

Applicant: Wei-Chih Chen ,  Michael A. Michaud ,  Kenneth C. Hou

Inventor： Wei-Chih Chen ,  Michael A. Michaud ,  Kenneth C. Hou

IPC: B01D15/00 ,  B01J20/28 ,  B01J20/32 ,  B01J39/16 ,  B01J39/22 ,  B01J39/26 ,  B01J45/00 ,  B01J47/00 ,  B01J47/12 ,  C02F1/28

CPC classification number: C02F1/288 ,  B01D15/00 ,  B01D15/361 ,  B01J20/103 ,  B01J20/24 ,  B01J20/261 ,  B01J20/264 ,  B01J20/28057 ,  B01J20/28078 ,  B01J20/3204 ,  B01J20/3212 ,  B01J20/3217 ,  B01J20/3274 ,  B01J20/3276 ,  B01J20/3289 ,  B01J39/165 ,  B01J39/22 ,  B01J39/26 ,  B01J45/00 ,  B01J47/007 ,  B01J47/12 ,  B01J2220/46 ,  B01J2220/4825 ,  B01J2220/58 ,  B01J2220/60

Abstract: An ion-exchange media comprising a modified polysaccharide material and a modified silica material, said modified materials comprising a polysaccharide and silica materials covalently bonded to a synthetic polymer, said synthetic polymer comprising a copolymer made from a polymerization of:(a) a polymerizable compound having a chemical group capable of covalently coupling, directly or indirectly, to said materials; and(b) a polymerizable compound containing (i) an ionizable chemical group or (ii) a chemical group capable of transformation to an ionizable chemical group.The media is used to selectively remove heavy metal contaminants from aqueous solutions containing said contaminants.

Abstract translation: 一种包含改性多糖材料和改性二氧化硅材料的离子交换介质，所述改性材料包括共价键合到合成聚合物上的多糖和二氧化硅材料，所述合成聚合物包含由以下聚合制成的共聚物：（a）可聚合化合物 具有能够直接或间接地共价连接到所述材料的化学基团; 和（b）可聚合化合物，其含有（i）可电离化学基团或（ii）能够转化为可电离化学基团的化学基团。 介质用于选择性地从含有所述污染物的水溶液中除去重金属污染物。

公开(公告)号：US4687820A

公开(公告)日：1987-08-18

申请号：US857513

申请日：1986-04-22

Applicant: Kenneth C. Hou ,  Tung-Ping D. Liao

Inventor： Kenneth C. Hou ,  Tung-Ping D. Liao

IPC: B01J20/32 ,  B01J39/26 ,  D06M3/02 ,  C08L89/00 ,  D06M13/20

CPC classification number: B01J39/26 ,  B01J20/24 ,  B01J20/261 ,  B01J20/264 ,  B01J20/28016 ,  B01J20/28023 ,  B01J20/28035 ,  B01J20/286 ,  B01J20/287 ,  B01J20/3092 ,  B01J20/3212 ,  B01J20/3217 ,  B01J20/3276 ,  B01J20/3278 ,  B01J2220/4812 ,  B01J2220/54 ,  B01J2220/58

Abstract: A modified polypeptide material comprising an insoluble polypeptide carrier and synthetic polymer, the synthetic polymer made from (a) a polymerizable compound which has a chemical group capable of covalent coupling to the insoluble polypeptide carrier and (b) one or more polymerizable compounds containing an ionizable chemical group, a chemical group capable of transformation to an ionizable chemical group, a group capable of causing the covalent coupling of the synthetic polymer to an affinity ligand or a biologically active molecule, or a hydrophobic chemical group. The synthetic polymer is covalently bonded to the insoluble polypeptide carrier.

Abstract translation: 一种修饰的多肽材料，其包含不溶性多肽载体和合成聚合物，所述合成聚合物由（a）具有能够与不溶性多肽载体共价偶联的化学基团的可聚合化合物和（b）一种或多种含可离子化的可聚合化合物 化学基团，能够转化为可电离化学基团的化学基团，能够使合成聚合物与亲和配体或生物活性分子共价偶联的基团或疏水性化学基团。 合成聚合物共价键合到不溶性多肽载体上。

公开(公告)号：US4645567A

公开(公告)日：1987-02-24

申请号：US722417

申请日：1985-04-11

Applicant: Kenneth C. Hou ,  Eugene A. Ostreicher

Inventor： Kenneth C. Hou ,  Eugene A. Ostreicher

IPC: A23L2/72 ,  B01D39/00 ,  B01D39/14 ,  B01D39/18 ,  D21H17/68 ,  D21H27/08 ,  D21H3/66 ,  D21H3/78

CPC classification number: D21H17/68 ,  A23L2/72 ,  B01D39/00 ,  B01D39/14 ,  B01D39/18 ,  D21H27/08

Abstract: Process for production of anionically charged filter media sheet including pretreatment of filter elements with cationic charge modifier, preferably, employing inorganic colloidal silica charge modifiers. The resulting filters are used for the removal of haze or haze formers from beverages.

Abstract translation: 用于生产阴离子电荷过滤介质片的方法，包括用阳离子电荷调节剂预处理过滤元件，优选使用无机胶体二氧化硅电荷改性剂。 所得的过滤器用于从饮料中除去雾度或雾度形成剂。

公开(公告)号：US4578150A

公开(公告)日：1986-03-25

申请号：US401361

申请日：1982-07-23

Applicant: Kenneth C. Hou

Inventor： Kenneth C. Hou

IPC: A61L2/00 ,  A61L2/02 ,  B01D15/08 ,  B01D39/00 ,  B01D39/14 ,  B01D39/18 ,  B01J20/28 ,  D21H17/53 ,  D21H17/69 ,  D21H21/52 ,  G01N30/52 ,  D21H3/60

CPC classification number: B01J20/28028 ,  A61L2/0017 ,  A61L2/022 ,  B01D15/08 ,  B01D39/00 ,  B01D39/14 ,  B01D39/18 ,  B01J20/28004 ,  B01J20/28033 ,  B01J20/28052 ,  D21H17/53 ,  D21H17/69 ,  D21H21/52 ,  G01N2030/528

Abstract: A self supporting fibrous matrix containing immobilized therein at least about 5% by weight of micro-particulate, with an average diameter less than 1 micron, preferably fumed silica, or alumina, and flocculating amounts of a neutral organic polymeric resin having oxygen atoms along the backbone thereof, is useful for fluid treatment and filtration processes, especially delipidization and depyrogenation of fluids such as serum.

Abstract translation: 一种自支撑纤维基体，其中固定有至少约5重量％的微粒，平均直径小于1微米，优选热解二氧化硅或氧化铝，以及絮凝量的具有氧原子的中性有机聚合物树脂沿着 其主链可用于流体处理和过滤过程，特别是诸如血清的流体的去脂肪化和去热原化。

公开(公告)号：US4511473A

公开(公告)日：1985-04-16

申请号：US347360

申请日：1982-02-09

Applicant: Kenneth C. Hou

Inventor： Kenneth C. Hou

IPC: A61K35/16 ,  A61L2/00 ,  B01D39/00 ,  B01D39/14 ,  B01J20/28 ,  B01D39/04 ,  B01D39/06

CPC classification number: B01J20/28028 ,  A61K35/16 ,  A61L2/0017 ,  B01D39/00 ,  B01D39/14 ,  B01J20/28004 ,  B01J20/28033 ,  B01J20/28052

Abstract: A self supporting fibrous matrix containing immobilized therein at least about 5% by weight of micro-particulate, with an average diameter less than 1 micron, preferably fumed silica, or alumina, and flocculating amounts of an organic polycationic resin and an organic polyanionic resin, is useful for fluid treatment and filtration processes, especially delipidization and depyrogenation of fluids such as serum.

Abstract translation: 一种自支撑纤维基质，其中固定有至少约5重量％的微粒，平均直径小于1微米，优选热解二氧化硅或氧化铝，以及絮凝量的有机聚阳离子树脂和有机聚阴离子树脂， 可用于流体处理和过滤过程，特别是流体如血清的去脂化和去热原化。

公开(公告)号：US06565749B1

公开(公告)日：2003-05-20

申请号：US09628632

申请日：2000-07-31

Applicant: Kenneth C. Hou ,  Donald S. Bretl ,  Richard D. Hembree

Inventor： Kenneth C. Hou ,  Donald S. Bretl ,  Richard D. Hembree

IPC: B01D7156

CPC classification number: C02F1/003 ,  A61L2/0017 ,  A61L2/022 ,  C02F1/28 ,  C02F1/50 ,  C02F2307/06

Abstract: A filter for removing microorganisms from a fluid is provided by the invention. The filter includes a substrate having a reactive surface, and a polymer covalently bonded to the reactive surface of the substrate. The polymer includes a plurality of cationic groups for attracting microorganisms. Faucet mounted filters and pour through filters containing the polymer coated substrate are provided. Also disclosed are methods for using and manufacturing filters for removing microorganisms from a fluid.

Abstract translation: 本发明提供一种从流体中除去微生物的过滤器。 过滤器包括具有反应性表面的基底和共价键合到基底的反应性表面的聚合物。 聚合物包括多个用于吸引微生物的阳离子基团。 提供水龙头安装的过滤器并倒入含有聚合物涂覆的基材的过滤器。 还公开了使用和制造用于从流体中除去微生物的过滤器的方法。

公开(公告)号：US4791063A

公开(公告)日：1988-12-13

申请号：US758064

申请日：1985-07-23

Applicant: Kenneth C. Hou ,  Chung-Jen Hou ,  Haunn-Lin Chen

Inventor： Kenneth C. Hou ,  Chung-Jen Hou ,  Haunn-Lin Chen

IPC: B01J20/28 ,  B01J20/32 ,  B01J39/22 ,  B01J41/16 ,  B01J47/12 ,  C08F251/00 ,  C08G81/02 ,  G01N30/38 ,  G01N30/60 ,  C12N1/00

CPC classification number: B01J20/28026 ,  B01J20/28028 ,  B01J20/28033 ,  B01J20/28052 ,  B01J20/3212 ,  B01J20/3248 ,  B01J20/3251 ,  B01J20/3255 ,  B01J39/22 ,  B01J41/16 ,  B01J47/123 ,  C08F251/00 ,  C08G81/02 ,  G01N2030/386 ,  G01N30/6091 ,  Y10S435/803

Abstract: Polyionene-transformed modified polymer-polysaccharide separation matrix and use thereof in removing contaminants of microorganism origin from biological liquids are disclosed.

Abstract translation: 公开了聚苯乙烯转化的改性聚合物 - 多糖分离基质及其在从生物液体中除去微生物来源污染物的用途。

公开(公告)号：US4673504A

公开(公告)日：1987-06-16

申请号：US649561

申请日：1984-09-11

Applicant: Eugene A. Ostreicher ,  Rodney A. Knight ,  Joseph V. Fiore ,  George T. Emond ,  Kenneth C. Hou

Inventor： Eugene A. Ostreicher ,  Rodney A. Knight ,  Joseph V. Fiore ,  George T. Emond ,  Kenneth C. Hou

IPC: A61L2/00 ,  A61L2/02 ,  B01D67/00 ,  B01D71/56 ,  B01D13/00

CPC classification number: B01D67/0093 ,  A61L2/0017 ,  A61L2/022 ,  B01D67/0011 ,  B01D71/56 ,  B01D2323/12 ,  B01D2323/30 ,  B01D2325/36

Abstract: A cationic charge modified microporous membrane comprising a hydrophilic organic polymeric microporous membrane and a cationic charge modifying agent bonded to substantially all of the wetted surfaces of the membrane, the charge modifying agent being an epichlorohydrin modified polyamide having tertiary amine or quaternary ammonium groups. A secondary charge modifying agent may be employed selected from: (i) aliphatic polyamines having at least one primary amine or at least two secondary amines; and (ii) aliphatic amines having at least one secondary amine and a carboxyl or hydroxyl substituent. Processes for producing and using the membrane are also described.

Abstract translation: 一种阳离子电荷改性微孔膜，其包含亲水性有机聚合物微孔膜和与膜的基本上所有润湿表面结合的阳离子电荷改性剂，电荷改性剂是具有叔胺或季铵基团的表氯醇改性聚酰胺。 可以使用次要电荷改性剂，其选自：（i）具有至少一个伯胺或至少两个仲胺的脂族多胺; 和（ii）具有至少一个仲胺和羧基或羟基取代基的脂族胺。 还描述了用于生产和使用膜的方法。