公开(公告)号：US06875734B2

公开(公告)日：2005-04-05

申请号：US10769963

申请日：2004-02-02

Applicant: Gerd Reinhardt ,  Ekaterina Jonas ,  Daniel Kewitz ,  Aylin Karadag ,  Hans Prehler

Inventor： Gerd Reinhardt ,  Ekaterina Jonas ,  Daniel Kewitz ,  Aylin Karadag ,  Hans Prehler

IPC: D06L3/02 ,  C07F13/00 ,  C07F15/02 ,  C11D3/39 ,  C11D7/18 ,  C11D7/32 ,  C11D7/38 ,  C11D7/54

CPC classification number: C11D3/3932

Abstract: The use of compounds of the formula (1) M(L)nXm  (1) where M is a metal atom from the group Mn, Fe, Co, Ni, Mo, W, L is a ligand from the group of nitrogen-containing heterocycles, X is chloride, bromide, nitrate, perchlorate, sulfate, ammonia, tetrafluoroborate, hexafluorophosphate or an anion of an organic acid having 1 to 22 carbon atoms, n is a number from 2 to 4 and m is a number from 0 to 4, as catalyst for peroxygen compounds, in particular in washing, bleaching and cleaning compositions is claimed.

Abstract translation: 使用式（1）的化合物，其中M是Mn，Fe，Co，Ni，Mo，W，L中的金属原子，是来自含氮杂环基团的配体，X是氯化物，溴化物，硝酸盐 ，高氯酸盐，硫酸盐，氨，四氟硼酸盐，六氟磷酸盐或具有1至22个碳原子的有机酸的阴离子，n为2至4的数，m为0至4的数，作为过氧化合物的催化剂，特别是 在洗涤中，要求保护漂白和清洁组合物。

公开(公告)号：US20050054550A1

公开(公告)日：2005-03-10

申请号：US10897838

申请日：2004-07-23

Applicant: Georg Borchers ,  Alexander Lerch ,  Gerd Reinhardt

Inventor： Georg Borchers ,  Alexander Lerch ,  Gerd Reinhardt

IPC: C07C303/44 ,  C07C309/42 ,  C11D1/22 ,  C11D3/42 ,  C11D11/00 ,  C11D1/00

CPC classification number: C11D3/3935 ,  C09B23/148 ,  C11D1/22 ,  C11D3/42 ,  C11D11/0082

Abstract: A process is claimed for preparing granulated acyloxybenzenesulfonates which consists in granulating a mixture composed essentially of acyloxybenzenesulfonate and optical brightener.

Abstract translation: 要求一种制备粒状酰氧基苯磺酸盐的方法，其包括将基本上由酰氧基苯磺酸盐和荧光增白剂组成的混合物制粒。

公开(公告)号：US06822113B2

公开(公告)日：2004-11-23

申请号：US10431951

申请日：2003-05-08

Applicant: Gerd Reinhardt ,  Peter Naumann ,  Alexander Lerch ,  Wolf-Dieter Mueller ,  Narayan D. Sadanani

Inventor： Gerd Reinhardt ,  Peter Naumann ,  Alexander Lerch ,  Wolf-Dieter Mueller ,  Narayan D. Sadanani

IPC: C07C6900

CPC classification number: C07C303/32 ,  C07C303/22 ,  C07C309/42

Abstract: A process for preparing acyloxybenzenesulfonates by reacting anhydrous phenolsulfonates with carboxylic acid derivatives comprises conducting the reaction with a salt of a phenolsulfonic acid which has a water content of less than 0.5% by weight and has been contacted with a substance having basic properties.

公开(公告)号：US06746996B2

公开(公告)日：2004-06-08

申请号：US10052123

申请日：2002-01-17

Applicant: Gerd Reinhardt ,  Michael Seebach ,  Nicole Reichardt ,  Laszlo I. Simandi ,  Tatiana M. Simandi ,  Gabor Besenyei

Inventor： Gerd Reinhardt ,  Michael Seebach ,  Nicole Reichardt ,  Laszlo I. Simandi ,  Tatiana M. Simandi ,  Gabor Besenyei

IPC: C11D738

CPC classification number: C11D3/3932

Abstract: Transition metal complexes used as bleach catalysts of the formula (1) M(L)nXm  (1) where M is a metal atom from the group Mn, Fe, Co, Ni, Mo, W, L is a ligand of the formula R1R2C═N—O(H)z R1 is C1-C22-alkyl, C2-C22-alkenyl or C5-C24-aryl, R2 is H, C1-C22-alkyl, C2-C22-alkenyl, C5-C24-aryl or where z=0 or 1, X is a neutral or anion ligand from the group consisting of pyridines, imidazolines, methylimidazoles, picolines, lutidines, chloride, bromide, nitrate, perchlorate, citrate, hexafluorophosphate or anions of organic acids having C1-C22 carbon atoms, n is a number from 2 to 4 and m is a number from 0 to 4.

Abstract translation: 用作式（1）的漂白催化剂的过渡金属络合物其中M是Mn，Fe，Co，Ni，Mo，W，L中的金属原子，式R的配体是C 1 -C 22烷基，C 2 -C 22 - 烯基或C 5 -C 24 - 芳基，R 2是H，C 1 -C 22 - 烷基，C 2 -C 22 - 烯基，C 5 -C 24 - 芳基或其中z = 0或1，X是来自吡啶的中性或阴离子配体 ，咪唑啉，甲基咪唑，吡啶甲酸，l啶，氯化物，溴化物，硝酸盐，高氯酸盐，柠檬酸盐，六氟磷酸盐或具有C 1 -C 22碳原子的有机酸阴离子，n为2至4的数，m为0至4的数。

公开(公告)号：US5610318A

公开(公告)日：1997-03-11

申请号：US455351

申请日：1995-05-31

Applicant: Frank Jaekel ,  Gerd Reinhardt ,  Wolf-Dieter M uller

Inventor： Frank Jaekel ,  Gerd Reinhardt ,  Wolf-Dieter M uller

IPC: C07D207/452 ,  C07D207/40 ,  C07D209/48 ,  C07D211/88 ,  C07D223/10 ,  C07D275/02 ,  C07D275/06 ,  C07D279/02 ,  C07D281/02 ,  C07D401/06 ,  C07D401/10 ,  C07D403/06 ,  C07D403/10 ,  C07D417/06 ,  C07D417/10 ,  C11D3/39 ,  C11D3/395 ,  C11D3/48 ,  C11D7/54 ,  D06L3/02 ,  C07D207/02

CPC classification number: C07D207/40 ,  C07D209/48 ,  C11D3/392

Abstract: This invention is directed to a process for preparing a compound containing a persalt activators and salts thereof which are derived from imidocarboxylic acids and sulfimidocarboxylic acids of the formula I: ##STR1## in which A is a group of the formula ##STR2## n is the number 0, 1 or 2, R.sup.1 is hydrogen, chlorine, bromine, C.sub.1 -C.sub.20 -alkyl, C.sub.2 -C.sub.20 -alkenyl, aryl, or alkylaryl,R.sup.2 is hydrogen, chlorine, bromine, --SO.sub.3 M, --CO.sub.2 M or --OSO.sub.3 M, X is C.sub.1 -C.sub.19 -alkylene or arylene,B is a group of the formula C.dbd.O or SO.sub.2,L is a leaving group.

Abstract translation: 本发明涉及一种制备含有衍生自式I的亚氨基羧酸和亚磺酰亚胺羧酸的含有活性剂及其盐的化合物的方法：其中A是下式的基团： n是数字0,1或2，R1是氢，氯，溴，C1-C20-烷基，C2-C20-烯基，芳基或烷基芳基，R2是氢，氯，溴， SO 3 M，-CO 2 M或-OSO 3 M，X为C 1 -C 19 - 亚烷基或亚芳基，B为式C = O或SO 2的基团，L为离去基团。

公开(公告)号：US5359127A

公开(公告)日：1994-10-25

申请号：US957447

申请日：1992-10-06

Applicant: Gerd Reinhardt

Inventor： Gerd Reinhardt

IPC: B01F17/06 ,  C07C67/00 ,  C07C261/00 ,  C07C301/00 ,  C07C303/22 ,  C07C303/32 ,  C07C309/03 ,  C07C309/08 ,  C07C309/12 ,  C11D1/28

CPC classification number: C07C309/00

Abstract: Process for the preparation of acyloxyalkanesulfonatesProcess for the preparation of acyloxyalkanesulfonates of the formula ##STR1## where R denotes C.sub.7 -C.sub.21 -alkyl or C.sub.7 -C.sub.21 -alkenyl, A denotes C.sub.2 -C.sub.4 -alkylene and M denotes an alkali metal atom or an alkaline earth metal atom, by esterification of carboxylic acids using salts of hydroxyalkanesulfonic acids, under mild reaction conditions, carboxylic acids of the general formula R--CO.sub.2 H being esterified using a salt of the formula HO--A--SO.sub.3 M in the presence of aqueous hydrochloric acid.

Abstract translation: 制备酰氧基烷基磺酸盐的方法制备式IMAMA的酰氧基烷基磺酸盐的方法，其中R表示C 7 -C 21 - 烷基或C 7 -C 21 - 烯基，A表示C 2 -C 4亚烷基，M表示碱金属原子或碱 在温和的反应条件下，通过使用羟基链烷磺酸的盐酯化羧酸，通过使用式HO-A-SO 3 M的盐在盐酸水溶液的存在下将通式为R-CO 2 H的羧酸酯化。

公开(公告)号：US5149864A

公开(公告)日：1992-09-22

申请号：US703461

申请日：1991-05-21

Applicant: Hanspeter Gethoffer ,  Gerd Reinhardt ,  Peter Naumann

Inventor： Hanspeter Gethoffer ,  Gerd Reinhardt ,  Peter Naumann

IPC: A01N47/28 ,  C07C407/00 ,  C07C409/40 ,  C11D3/39 ,  C11D7/54

CPC classification number: C07C409/40 ,  C11D3/3945

Abstract: Compounds of the formula ##STR1## where y is 1 or 2,A is hydrogen, C.sub.1 -C.sub.2 -alkyl, aryl or a group of the formula ##STR2## if y is 1, or C.sub.2 -C.sub.20 -alkylene or arylene if y is 2, R.sup.1 and R.sup.2 can be identical or different and each is hydrogen, C.sub.1 -C.sub.20 -alkyl, aryl, haloaryl, alkoxyaryl or alkylaryl, or else R.sup.1 and R.sup.2 together are a C.sub.2 -C.sub.4 -alkylene radical,x is 0 or 1,B is a group of the formula ##STR3## n is from 1 to 20, m is 0, 1 or 2,R.sup.3 is C.sub.1 -C.sub.20 -alkyl andR.sup.4 is in each case hydrogen or C.sub.1 -C.sub.20 -alkyl.These compounds are suitable for use as bleaching, oxidizing or disinfecting agents.

Abstract translation: 其中y为1或2的化合物，如果y为1，则A为氢，C1-C2-烷基，芳基或式为IMA的基团，如果y为1，则为C2-C20-亚烷基或亚芳基 2，R 1和R 2可以相同或不同，各自为氢，C 1 -C 20 - 烷基，芳基，卤代芳基，烷氧基芳基或烷基芳基，或者R 1和R 2一起为C 2 -C 4亚烷基，x为0或1， B是下式的基团：n为1至20，m为0,1或2，R 3为C 1 -C 20烷基，R 4为氢或C 1 -C 20 - 烷基。 这些化合物适用于漂白，氧化或消毒剂。

公开(公告)号：US5118668A

公开(公告)日：1992-06-02

申请号：US221835

申请日：1988-07-20

Applicant: Ernst-August Auerswald ,  Wolfgang Bruns ,  Dietrich Horlein ,  Gerd Reinhardt ,  Eugen Schnabel ,  Werner Schroder

Inventor： Ernst-August Auerswald ,  Wolfgang Bruns ,  Dietrich Horlein ,  Gerd Reinhardt ,  Eugen Schnabel ,  Werner Schroder

IPC: C12N9/99 ,  A61K38/00 ,  A61K38/55 ,  A61P9/00 ,  A61P29/00 ,  C07K14/00 ,  C07K14/81 ,  C12N1/21 ,  C12N15/09 ,  C12P21/02

CPC classification number: C07K14/8117 ,  A61K38/00

Abstract: Peptides having essentially the sequence of bovine pancreatic trypsin inhibitor (aprotinin) wherein one or more of the amino acids at positions 15, 16, 17, 18, 34, 39 and 52 are replaced by any naturally occurring amino acid produced by recombinant DNA technology, process, expression vector and recominant host therefor and pharmaceutical use thereof. Such peptides being useful as therapeutic agents in diseases connected with the presence of excessive amounts of proteinases.

Abstract translation: 具有基本上具有牛胰蛋白酶抑制剂（抑肽酶）的序列的肽，其中15,16,17,18,39,35和52位的氨基酸中的一个或多个被任何由重组DNA技术产生的天然存在的氨基酸替代， 方法，表达载体及其重组宿主及其药物用途。 这些肽在与过量蛋白酶的存在相关的疾病中可用作治疗剂。

公开(公告)号：US08889611B2

公开(公告)日：2014-11-18

申请号：US13513729

申请日：2010-11-30

Applicant: Gerd Reinhardt ,  Michael Best

Inventor： Gerd Reinhardt ,  Michael Best

IPC: C11D7/26 ,  C11D7/32 ,  C11D7/54 ,  C07F13/00 ,  C11D17/06 ,  C11D17/00 ,  C11D3/16 ,  C11D3/39 ,  D21C9/10 ,  D21C9/16

CPC classification number: C07F13/005 ,  C11D3/168 ,  C11D3/3932 ,  C11D17/0052 ,  C11D17/06 ,  C11D17/065 ,  D21C9/10 ,  D21C9/163

Abstract: The invention relates to compounds in solid form, containing a) one or more manganese complex compounds of the general formula (1), where M is independently selected from manganese in the III or IV oxidation state, X is independently a co-ordinating or bridging species selected from H2O, O22−, O2−, O2−, OH−, HO2−, SH−, S2−, SO, Cl−, N3−, SCN−, N3−, RCOO−, NH2− and NR3, where R is a radical selected from H, alkyl and aryl, L are independently organic ligands, each of which contains at least two nitrogen atoms co-ordinated on manganese, z is an integer from −4 to +4, Y is a monovalent or multivalent counter-ion selected from chloride, sulphate, hydrogen sulphate, nitrate and acetate, which leads to charge neutrality of the complex, and q is an integer from 1 to 4, and b) one or more salts of the general formula R′—C6H4—SO3Me, where R′ is CH3 or C2H5 and denotes Me, Na, K, Ca or Mg, characterized in that the molar ratio of the manganese complex compound of the general formula (1) to salt of the general formula R′—C6H4—SO3Me is 1:0.5 to 1:5. The invention also describes a method for producing the compounds and to the use thereof as oxidation catalysts or bleach catalysts, in particular in detergents or cleaning agents.

Abstract translation: 本发明涉及固体形式的化合物，其包含a）一种或多种通式（1）的锰络合物，其中M独立地选自III或IV氧化态的锰，X独立地为配位或桥接 选自H2O，O22-，O​​2-，O2-，OH-，HO2-，SH-，S2-，SO，Cl-，N3-，SCN-，N3-，RCOO-，NH2-和NR3的物质，其中R 是选自H，烷基和芳基的基团，L独立为有机配体，每个含有至少两个在锰上配位的氮原子，z为-4至+4的整数，Y为单价或多价计数器 其选自氯化物，硫酸盐，硫酸氢盐，硝酸盐和乙酸盐，这导致络合物的电荷中性，q是1至4的整数，b）一种或多种通式R'-C6H4- SO 3 Me，其中R'是CH 3或C 2 H 5，并且表示Me，Na，K，Ca或Mg，其特征在于锰络合物 通式（1）表示的化合物与通式R'-C6H4-SO3Me的盐为1:0.5至1:5。 本发明还描述了一种制备化合物的方法及其用作氧化催化剂或漂白催化剂的用途，特别是在洗涤剂或清洁剂中。

公开(公告)号：US08846921B2

公开(公告)日：2014-09-30

申请号：US13877567

申请日：2011-10-06

Applicant: Christian Sidot ,  Audrey Caron ,  Miriam Ladwig ,  Gerd Reinhardt

Inventor： Christian Sidot ,  Audrey Caron ,  Miriam Ladwig ,  Gerd Reinhardt

IPC: C07F15/02 ,  C07F13/00

CPC classification number: C07F15/02 ,  C07F13/00 ,  C07F13/005 ,  C07F15/025

Abstract: The invention relates to a method for producing metal complexes of formula (2) [MaLxXn]Ym (2), where M is a metal from the group consisting of Mn(II), Mn(III), Mn(IV), Fe(II), Fe(III) or Fe(IV), X is a coordinating compound selected from mono-, bi- or tri-charged anions or neutral molecules which can coordinate to a metal in mono-, bi- or tri-dentate form, Y represents a non-coordinating counter-ion which ensures charge equalization of the complex, L represents a ligand of formula (1) or the protonized or de-protonized form thereof, and a, x, n, m, R, R1, R2, R3 and z have the meanings described in claim 1. Said method is characterized in that the reaction of one or more ligands of formula (1) with an iron salt or manganese salt is carried out in an acetone/water mixture in a temperature range from 0 to 50° C. and for this purpose a solution or a suspension of the one or more ligands of formula (1) in acetone is brought in contact with an aqueous metal salt solution of the iron salt or manganese salt in the temperature range in which the reaction takes place.

Abstract translation: 本发明涉及一种制备式（2）[MaLxXn] Ym（2）的金属配合物的方法，其中M是由Mn（II），Mn（III），Mn（IV），Fe（ II），Fe（III）或Fe（IV），X是选自单，双或三电荷阴离子或中性分子的配位化合物，其可以以单，双或三齿形式与金属配位 ，Y表示非配位抗衡离子，其确保络合物的电荷均衡，L表示式（1）的配体或其质子化或去质子化形式，和a，x，n，m，R，R 1， R2，R3和z具有权利要求1所述的含义。所述方法的特征在于，式（1）的一种或多种配体与铁盐或锰盐的反应在丙酮/水混合物中在温度 范围为0至50℃，为此目的，将式（1）的一种或多种配体在丙酮中的溶液或悬浮液与铁盐水溶液的金属盐溶液接触 r锰盐在发生反应的温度范围内。