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    Medicine container with single pill dispenser
    23.
    发明授权
    Medicine container with single pill dispenser 有权
    医药容器带单药丸分配器

    公开(公告)号：US07988016B2

    公开(公告)日：2011-08-02

    申请号：US12367236

    申请日：2009-02-06

    Applicant: Seth A. Klein ,  Michael R. Klein

    Inventor： Seth A. Klein ,  Michael R. Klein

    IPC: B65H3/00 ,  B65D83/00

    CPC classification number: B65D83/0409 ,  B65D50/062

    Abstract: A pill dispensing cap that secures to a conventional pill container. The pill dispensing cap has a lower cap, a pill discharge port, and a spring loaded rotatable and slidable upper cap. Pills are dispensed one at a time, and the remaining pills are isolated from external contamination. A child resistant lock prevents small children and/or mentally handicapped individuals from easily accessing medicine inside the container. The child resistant lock uses a vertically slidable upper cap that is slidably and rotatably attached to the lower cap. A child safety lock uses a key in the upper cap that must be aligned with a slot in the lower cap to allow a pill to be dispensed. When the key and slot are aligned, the upper cap is vertically compressed against the lower cap. As the upper cap moves toward the base cap, a gravity fed pill discharge port is exposed which releases a single pill.

    Abstract translation: 药丸分配帽，固定到常规药丸容器。 药丸分配帽具有下盖，药丸排出口和弹簧加载的可旋转和可滑动的上盖。 药片一次分配一次，剩余的药丸与外部污染物分离。 儿童防护锁可防止小孩和/或弱智人士容易地进入集装箱内的药物。 防儿童锁使用可滑动和可旋转地附接到下盖的可垂直滑动的上盖。 儿童安全锁使用上盖中的一个必须与下盖中的槽对齐的钥匙，以允许药丸被分配。 当键和槽对齐时，上盖相对于下盖垂直压缩。 当上盖向基盖移动时，暴露重力进料药丸排出口，释放单个药丸。

    Fuel filter system
    24.
    发明申请
    Fuel filter system 审中-公开
    燃油滤清器系统

    公开(公告)号：US20080035537A1

    公开(公告)日：2008-02-14

    申请号：US11889048

    申请日：2007-08-08

    Applicant: Gunnar-Marcel Klein ,  Guenter Jokschas ,  Martin Klein

    Inventor： Gunnar-Marcel Klein ,  Guenter Jokschas ,  Martin Klein

    IPC: B01D35/02 ,  B01D35/16 ,  B01D35/18 ,  B01D36/00

    CPC classification number: B01D27/148 ,  B01D36/003

    Abstract: A fuel filter system characterized by a simple design provided with a coalescer element (20) disposed in the immediate fuel inlet region for improving the elimination of water droplets. The coalescer element includes an upper end plate (26) that extends to the inner wall of the housing (10), thereby sealing the coalescer element as well as the inlet region and the outer unfiltered fluid region. The coalescer element (20) and the particle filter (19) are arranged on a common separating element (25), which rests against the discharge tube (17) located in the center of the fuel filter via a profiled seal. The end plate of the coalescer element can be produced with the profiled elastomeric seal molded thereon by two-component injection molding or by overmolding.

    Abstract translation: 一种燃料过滤系统，其特征在于简单的设计，其具有设置在直接燃料入口区域中的聚结器元件（20），用于改善水滴的消除。 聚结器元件包括延伸到壳体（10）的内壁的上端板（26），从而密封聚结器元件以及入口区域和外部未过滤流体区域。 聚结器元件（20）和颗粒过滤器（19）布置在公共分离元件（25）上，该分离元件（25）通过异型密封件靠在位于燃料过滤器中心的排放管（17）。 聚结器元件的端板可以通过双组分注塑成型或通过包覆成型在其上模压成型的弹性密封件来制造。

    Compounds with chelation affinity and selectivity for first transition series elements: use in medical therapy and diagnosis
    26.
    发明授权
    Compounds with chelation affinity and selectivity for first transition series elements: use in medical therapy and diagnosis 失效
    具有螯合亲和性和对第一过渡系列元素选择性的化合物：用于医学治疗和诊断

    公开(公告)号：US06469162B1

    公开(公告)日：2002-10-22

    申请号：US09664952

    申请日：2000-09-19

    Applicant: Harry S. Winchell ,  Joseph Y. Klein ,  Elliot D. Simhon ,  Rosa L. Cyjon ,  Ofer Klein ,  Haim Zaklad

    Inventor： Harry S. Winchell ,  Joseph Y. Klein ,  Elliot D. Simhon ,  Rosa L. Cyjon ,  Ofer Klein ,  Haim Zaklad

    IPC: C07D22500

    CPC classification number: C07D405/14 ,  A61K31/13 ,  A61K31/131 ,  A61K31/135 ,  A61K31/136 ,  A61K31/137 ,  A61K31/395 ,  A61K31/4025 ,  A61K31/415 ,  A61K31/44 ,  A61K31/675 ,  A61K47/54 ,  A61K47/547 ,  A61K49/0002 ,  A61K49/04 ,  A61K49/06 ,  A61K51/0478 ,  A61K51/0482 ,  C07D255/02 ,  C07D255/04 ,  C07D257/00 ,  C07D403/14 ,  C07D487/08 ,  C07D487/10 ,  C07F9/6515 ,  C07F9/6524 ,  C07F9/6561 ,  Y10S514/836

    Abstract: This invention involves synthesis and use of a class of compounds with chelation affinity and selectivity for first transition series elements. Administration of the free or conjugated compound, or physiological salts of the free or conjugated compound, results in decrease in the in vivo bioavailability of first transition series elements and/or removal from the body of first transition series elements and elements with similar chemical properties. These characteristics make such compounds useful in the management of diseases associated with a bodily excess of first transition series elements and elements with similar chemical properties. This invention demonstrates that such compounds inhibit mammalian, bacterial, and fungal cell replication and are therefore useful in the treatment of neoplasia, infection, inflammation, immune reponse, and in termination of pregnancy. Since these compounds are capable of descreasing the in vivo availability of tissue iron they are useful in management of free radical mediated tissue damage, and oxidation mediated tissue damage. When combined with radioisotopic or paramagnetic cations of first transition series elements, or elements with chemical properties similar to those of first transition series elements, prior to their administration, the resulting complexes are useful as diagnostic agents in nuclear medicine and magnetic resonance imaging (MRI).

    Abstract translation: 本发明涉及合成和使用具有螯合亲和性和对第一转变序列元件的选择性的一类化合物。 施用游离或缀合的化合物或游离或共轭化合物的生理盐导致第一过渡系列元件的体内生物利用度降低和/或从具有相似化学性质的第一过渡系列元件和元件的体内移除。 这些特征使得这些化合物可用于治疗与具有相似化学性质的第一过渡系列元件和元件的身体过剩相关的疾病。 本发明证明这些化合物抑制哺乳动物，细菌和真菌细胞复制，因此可用于治疗肿瘤形成，感染，炎症，免疫反应和终止妊娠。 由于这些化合物能够降低组织铁的体内可利用性，因此它们可用于管理自由基介导的组织损伤和氧化介导的组织损伤。 当与第一过渡系列元件的放射性同位素或顺磁性阳离子或具有与第一过渡系列元件类似的化学特性的元素组合时，在其给药之前，所得复合物可用作核医学和磁共振成像（MRI）中的诊断剂， 。

    Medical tool dispenser system
    28.
    发明授权
    Medical tool dispenser system 失效
    医疗工具分配器系统

    公开(公告)号：US5529490A

    公开(公告)日：1996-06-25

    申请号：US414774

    申请日：1995-03-31

    Applicant: Douglas J. Klein ,  Paul E. Klein

    Inventor： Douglas J. Klein ,  Paul E. Klein

    IPC: A61C7/30 ,  A61C3/00

    CPC classification number: A61C7/306 ,  Y10S206/805

    Abstract: A presenting/dispensing system for chain-interconnected, cut-separable orthodontic/medical devices, organized into groups having a pre-selected number of patient-usable units, including a container constructed for housing such devices, and presenting/dispensing aperture substructure formed therein to allow for presenting such devices and dispensing a desired number of the same in an indexed manner. The system also includes check structure associated with the presenting/dispensing aperture substructure, which check structure is changeable, as a result of dispensing action, to a first condition that accommodates dispensing of such devices, and to a second condition, upon termination of such action, that resists slipping back of a chain of devices into the container.

    Abstract translation: 一种用于链式互连，可分离切割的正畸/医疗装置的呈现/分配系统，组织成具有预选数量的患者可用单元的组，包括构造用于容纳这种装置的容器以及其中形成的呈现/分配孔子结构 以允许呈现这样的装置并以索引的方式分配所需数量的装置。 该系统还包括与呈现/分配孔径子结构相关联的检查结构，该检查结构可以作为分配动作的结果而变化到适应这种装置的分配的第一状态，并且在该动作终止时为第二状态 ，抵抗将一连串设备滑回到容器中。

    Orthodontic bracket-mounted traction hook
    30.
    发明授权
    Orthodontic bracket-mounted traction hook 失效
    正畸托架式牵引钩

    公开(公告)号：US4713001A

    公开(公告)日：1987-12-15

    申请号：US900330

    申请日：1986-08-25

    Applicant: Paul E. Klein ,  Douglas J. Klein

    Inventor： Paul E. Klein ,  Douglas J. Klein

    IPC: A61C7/12 ,  A61C7/00

    CPC classification number: A61C7/12

    Abstract: An orthodontic traction-hook device which is adapted for selective, removable attachment to posts in an orthodontic bracket. The device includes spaced, interconnected legs that are releasably engageable with such posts, and a projection operatively joined to such legs for receiving an orthodontic, traction-applying instrumentality, such as a conventional orthodontic elastomer unit.

    Abstract translation: 一种矫正牵引钩装置，其适于选择性地，可移除地附接到正畸托架中的柱。 该装置包括可释放地与这种柱接合的间隔开的互连腿，以及可操作地连接到这种腿以用于接收正畸，牵引应用工具的突出部，例如常规的正畸弹性体单元。

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