公开(公告)号：US3597429A

公开(公告)日：1971-08-03

申请号：US3597429D

申请日：1968-02-15

Applicant: MILES LAB

Inventor： HAYAO SHIN ,  STRYCKER WALLACE GLENN

IPC: C07D257/04 ,  C07D55/56 ,  C07D57/00

CPC classification number: C07D257/04

Abstract: A SERIES OF DERIVATIVES OF W-(5-SUBSTITUTED-2-TETRAZOLYL) ALKANOIC ACIDS THAT IS USEFUL AS ANTI-INFLAMMATORY AGENTS. THESE COMPOUNDS ARE PREPARED BY REACTING A TETRAZOLYL ACYL HALIDE WITH A SUITABLE AMINE OR A TETRAZOLE WITH AN APPROPRIATE HALOALKYL AMIDE OR ESTER.

公开(公告)号：US3585004A

公开(公告)日：1971-06-15

申请号：US3585004D

申请日：1969-03-21

Applicant: MILES LAB

Inventor： MAST RAYMOND L

IPC: G01N33/52 ,  G01N21/06 ,  G01N33/16

CPC classification number: G01N33/52 ,  Y10S436/903 ,  Y10T436/146666

Abstract: A TEST COMPOSITION AND DEVICE WHICH UNDERGOES AN ENHANCED COLOR CHANGE WHEN CONTACTED BY A COUPLABLE COMPOUND. THE COMPOSITION COMPRISES A DIAZONIUM SALT AND A LEWIS ACID HALIDE OR A COMPLEX OF A LEWIS ACID HALIDE AND AN ORGANIC LEWIS BASE. THE DEVICE IS PREPARED BY INCORPORATING IN A CARRIER THE DIAZONIUM SALT SOLUTION AND THE LEWIS ACID HALIDE OR COMPLEX THEREOF WITH AN ORGANIC LEWIS BASE. THE COMPOSITION AND DEVICE ARE USED IN A PROCESS FOR DETECTING COUPLABLE COMPOUNDS.

公开(公告)号：US3577490A

公开(公告)日：1971-05-04

申请号：US3577490D

申请日：1969-12-29

Applicant: MILES LAB

Inventor： WELSH THOMAS LAURENCE ,  PETERSON DONALD LEROY ,  HOSS GEORGE CARR ,  PALERMO BLASEY THOMAS

IPC: A61J3/10 ,  A61K9/46 ,  A61K7/16

CPC classification number: A61K9/0007 ,  A61J3/10 ,  Y10S514/96

Abstract: AN EFFERVESCENT TABLET IS PRODUCED BY PREPARING A POWDERED TABLETABLE COMPOSITION COMPRISING AN EFFERVESCENT COUPLE, AN ANTIMICROBIAL SUBSTANCE, A TABLETING LUBRICANT, AND PREFERABLY, A FLAVORING, SWEETENING AND/OR COLORING AGENT, MIXING THE SAME TO ACHIEVE UNIFORMITY, AND COMPRESSING INTO COHERENT TABLET FORM. THE LUBRICANT CAN BE FUMARIC ACID OR PARTICLES OF A LIQUID LUBRICANT COATED WITH AN OIL-INSOLUBLE FILM-FORMING SUBSTANCE. UPON DISSOLUTION, A SOLUTION HAVING ANTIMICROBIAL PROPERTIES IS PRODUCED. THE SOLUTION IS USEFUL FOR CLEANING SOLID SURFACES, PARTICULARLY, THE TEETH AND PERIODONTAL GUM AREAS OF THE ORAL CAVITY.

公开(公告)号：US3552925A

公开(公告)日：1971-01-05

申请号：US3552925D

申请日：1967-07-13

Applicant: MILES LAB

Inventor： FETTER MARION COOK

IPC: C12Q1/00 ,  C12Q1/54 ,  G01N33/49 ,  G01N33/50 ,  G01N33/52 ,  G01N31/06 ,  G01N31/22 ,  G01N33/16

CPC classification number: G01N33/5002 ,  C12Q1/00 ,  C12Q1/54 ,  G01N33/491 ,  G01N33/521 ,  Y10S435/805 ,  Y10T436/144444

Abstract: A METHOD FOR SEPARATING WHOLE BLOOD INTO A SUBSTANTIALLY COLORLESS FLUID AND THE RED CELL COMPONENTS OR RESIDUE COMPRISING CONTACTING THE WHOLE BLOOD WITH A WATERSOLUBLE SALT HAVING AN INORGANIC CATION SUCH AS POTASSIUM CITRATE, AMMONIUM SULFATE, ZINC SULFATE AND THE LIKE. IN A PREFERABLE USE OF THIS MEANS TO EFFECT A TEST DEVICE AND METHOD FOR DETECHING SOLUBLE CONSTITUENTS IN WHOLE BLOOD, A MATRIX CONTAINING THE SALT IS POSITIONED ADJACENT TO A TEST REAGENT SPECIFICALLY REACTABLE WITH AND GIVING A DETECTABLE RESPONSE TO SAID SOLUBLE CONSTITUENT, THE WHOLE BLOOD FIRST BEING CONTACTED WITH THE SALT AND THE COLORLESS FLUID THUS OBTAINED THEN CONTACTED WITH THE TEST REAGENT.

公开(公告)号：US3536702A

公开(公告)日：1970-10-27

申请号：US3536702D

申请日：1967-09-21

Applicant: MILES LAB

Inventor： HAYAO SHIN

IPC: C07D285/36 ,  C07D93/42

CPC classification number: C07D285/36

公开(公告)号：US3518274A

公开(公告)日：1970-06-30

申请号：US3518274D

申请日：1967-10-09

Applicant: MILES LAB

Inventor： STRYCKER WALLACE GLENN

IPC: C07D211/08 ,  C07D29/30

CPC classification number: C07D211/08

公开(公告)号：US3509153A

公开(公告)日：1970-04-28

申请号：US3509153D

申请日：1967-03-24

Applicant: MILES LAB

Inventor： HAYAO SHIN ,  GLENN WALLACE

IPC: C07D257/04 ,  C07D401/06 ,  C07D401/14 ,  C07D55/56

CPC classification number: C07D257/04 ,  C07D401/06 ,  C07D401/14

公开(公告)号：US3499890A

公开(公告)日：1970-03-10

申请号：US3499890D

申请日：1967-06-02

Applicant: MILES LAB

Inventor： SCHUT ROBERT NORMAN

IPC: C07D471/22 ,  C07D41/00 ,  A61K27/00

CPC classification number: C07D471/22

公开(公告)号：US3483090A

公开(公告)日：1969-12-09

申请号：US3483090D

申请日：1967-05-01

Applicant: MILES LAB

Inventor： BARTON RICHARD RUSSELL

IPC: C12N9/34 ,  C07G7/02

CPC classification number: C12N9/2428 ,  Y10S435/815

公开(公告)号：US3483084A

公开(公告)日：1969-12-09

申请号：US3483084D

申请日：1967-05-29

Applicant: MILES LAB

Inventor： STERNBERG MOSHE

IPC: C12N9/34 ,  C07G7/02 ,  C12D13/10

CPC classification number: C12N9/2428 ,  Y10S435/814 ,  Y10S435/913 ,  Y10S435/917 ,  Y10S435/918 ,  Y10S435/939