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公开(公告)号:US07704953B2
公开(公告)日:2010-04-27
申请号:US11627863
申请日:2007-01-26
IPC分类号: A61K38/00
CPC分类号: C07K14/001 , A61K47/62 , C07K2319/035 , C07K2319/33 , C12N15/1037
摘要: The present disclosure relates to the construction, expression, and selection of genes that encode novel Trp cage polypeptides with desirable cell and/or tissue binding properties, as well as the novel Trp cage polypeptides themselves. A polypeptide of this disclosure may contain all or part of amino acid sequence AAADX1YX2QWLX3X4X5GPX6SGRPPPX7 (SEQ ID NO: 4), wherein Xn represents an amino acid found in position n, the polypeptide comprising a tryptophan cage (Trp cage).
摘要翻译: 本公开涉及编码具有期望的细胞和/或组织结合特性的新型Trp笼多肽的基因的构建,表达和选择,以及新型Trp笼多肽本身。 本公开的多肽可以包含氨基酸序列AAADX1YX2QWLX3X4X5GPX6SGRPPPX7(SEQ ID NO:4)的全部或部分,其中Xn表示位置n中发现的氨基酸,所述多肽包含色氨酸笼(Trp笼)。
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公开(公告)号:US20050179289A1
公开(公告)日:2005-08-18
申请号:US10781299
申请日:2004-02-18
申请人: Mark Fuller , Sarah Fuller
发明人: Mark Fuller , Sarah Fuller
CPC分类号: A47D13/025 , B60N2/2812 , B60N2/2845
摘要: A child safety seat comprises a seat body having opposed side wall portions, a retention harness comprising opposed harness side portions, and a retention member carried on each side wall portion to connect and hold the latch of each harness side portion in a laterally spaced position from the other latch of the other harness side portion, which position is typically elevated relative to their position of use. This facilitates the placement of a child into the safety seat prior to latching the retention harness latches together.
摘要翻译: 儿童安全座椅包括具有相对的侧壁部分的座椅本体,包括相对的线束侧部分的保持线束和在每个侧壁部分上承载的保持构件,以将每个线束侧部分的闩锁以横向间隔开的位置 另一个线束侧部分的另一个闩锁,该位置通常相对于其使用位置而升高。 这有助于在将保持带闩锁锁定在一起之前将儿童放置到安全座椅中。
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公开(公告)号:US20050092527A1
公开(公告)日:2005-05-05
申请号:US10977481
申请日:2004-10-29
申请人: Tuong Le , Richard Giroux , Albert Odell , Gary Thompson , Deborah Banta , Robert Badrak , Gregory Galloway , Mark Fuller
发明人: Tuong Le , Richard Giroux , Albert Odell , Gary Thompson , Deborah Banta , Robert Badrak , Gregory Galloway , Mark Fuller
IPC分类号: E21B17/10
CPC分类号: E21B17/1064 , E21B17/1007 , Y10T29/49805
摘要: Apparatus and methods are provided for reducing drilling vibration during drilling with casing. In one embodiment, an apparatus for reducing vibration of a rotating casing includes a tubular body disposed concentrically around the casing, wherein tubular body is movable relative to the casing. Preferably, a portion of the tubular body comprises a friction reducing material. In operation, the tubular body comes into contact with the existing casing or the wellbore instead of the rotating casing. Because the tubular body is freely movable relative to the rotating casing, the rotating casing may continuously rotate even though the tubular body is frictionally in contact with the existing casing.
摘要翻译: 提供了设备和方法,用于在套管钻孔期间减少钻孔振动。 在一个实施例中,用于减少旋转壳体的振动的装置包括围绕壳体同心设置的管状体,其中管状体可相对于壳体移动。 优选地,管状体的一部分包括减摩材料。 在操作中,管状体与现有的外壳或井眼接触而不是旋转的壳体。 由于管状体相对于旋转壳体可自由移动,因此即使管状体与现有的套管摩擦接触,旋转壳也可以连续旋转。
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公开(公告)号:US4817312A
公开(公告)日:1989-04-04
申请号:US15970
申请日:1987-02-18
申请人: Mark Fuller , Alan S. Robinson
发明人: Mark Fuller , Alan S. Robinson
IPC分类号: B05B17/08
CPC分类号: B05B17/08
摘要: A sound activated fountain display. A plurality of transducers are disposed on the bottom of the pool of a fountain display with the fountain being normally off. Whenever a coin is tossed into the fountain's pool, the sound waves generated by the coin are received by the transducers, activating the fountain display. By gating the responses of the various transducers, the area of the pool in which the coin was tossed may be identified. In this manner, the display may be caused to be directed to that area of the pool, customizing the display for that particular viewer. If desired, the fountain display may be in a central pool with separate "satellite" coin pools surrounding the fountain and for activating the fountain display.
摘要翻译: 声音激活喷泉显示。 多个换能器设置在喷泉显示器的池的底部,喷泉通常关闭。 每当硬币被投掷到喷泉池中时,由硬币产生的声波被换能器接收,激活喷泉显示。 通过选择各种换能器的响应,可以识别投掷硬币的池的区域。 以这种方式,可以使显示器被引导到池的该区域,为该特定观看者定制显示。 如果需要,喷泉显示器可以在中央游泳池中,其中围绕喷泉的单独的“卫星”硬币池并且用于启动喷泉显示器。
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公开(公告)号:US10539305B2
公开(公告)日:2020-01-21
申请号:US15438630
申请日:2017-02-21
申请人: Mark Fuller , Riae Yoo , Scott Winslow , EunKyoung Kim
发明人: Mark Fuller , Riae Yoo , Scott Winslow , EunKyoung Kim
IPC分类号: F21L4/00 , F21V21/15 , H05B37/02 , F21S9/02 , F21V31/00 , H05B33/08 , F21V3/02 , B63B35/73 , F21W131/401 , F21Y115/00
摘要: A light display system and device for use in a body of water or other liquid is described. The light display device may be controlled remotely via a control hub and/or control panel, or controlled by internally preprogrammed commands. A plurality of light display devices may be controlled in selected, choreographed sequences to provide various unique visual displays including, for example, geometrical patterns and/or naturalistic patterns giving the impression of organic phenomena such as swarming fireflies, bioluminescent creatures and the like.
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公开(公告)号:US20190093841A1
公开(公告)日:2019-03-28
申请号:US16142718
申请日:2018-09-26
申请人: Mark Fuller
发明人: Mark Fuller
IPC分类号: F21S19/00 , F21S9/03 , H01L31/054 , H02S40/38
摘要: A light source generally comprising a light tube configured with artificial light sources and sustainable sources of energy is disclosed. The light source may provide natural light during daylight hours, and a combination of natural light and artificial light, or only artificial light during hours when natural light is diminished or not available. The resultant light output may be constant and the artificial light may be powered by sustainable energy sources such as solar panels and rechargeable batteries.
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公开(公告)号:US20170232464A1
公开(公告)日:2017-08-17
申请号:US15436718
申请日:2017-02-17
申请人: Mark Fuller
发明人: Mark Fuller
CPC分类号: B05B17/085 , B05B1/20 , B05B9/0423 , B05B12/02
摘要: A water display is described including a wall or other structure upon which streams of water are shot. The direction, velocity, pressure and flow rate of the water streams may be varied to provide entertaining visual effects, which may also be choreographed with music, lighting or other features.
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公开(公告)号:US20140312137A1
公开(公告)日:2014-10-23
申请号:US14212106
申请日:2014-03-14
申请人: Mark Fuller , Jim Doyle , Amnon Talmor
发明人: Mark Fuller , Jim Doyle , Amnon Talmor
摘要: A device to moving a water shooter is described. The device may contain features that allow the device to travel submerged in a reservoir with a water shooter attached. The device may travel along a fixed track, rotational boom, or be free swimming in order to move the water shooter within the reservoir so that unique water effects may be achieved.
摘要翻译: 描述了移动水枪的装置。 该装置可以包含允许装置在连接水枪的情况下潜入水库的特征。 该装置可以沿着固定轨道,旋转吊杆或自由游动,以便将水枪移动到储存器内,从而可以获得独特的水效应。
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公开(公告)号:US20140306024A1
公开(公告)日:2014-10-16
申请号:US14211069
申请日:2014-03-14
申请人: Mark Fuller , Jim Doyle , Scott Mahlerbee , John McLaughlin
发明人: Mark Fuller , Jim Doyle , Scott Mahlerbee , John McLaughlin
IPC分类号: B05B17/08
CPC分类号: B05B17/08 , B05B1/265 , B05B17/085
摘要: A water delivery device is described which includes an outlet pipe through which water is ejected to provide a water display. A disk is positioned relative to the outlet pipe. The relative positions of the disk and outlet pipe are moved so that the disk is located within the outlet pipe or above it to alter the appearance of the water leaving the outlet pipe. As the relative position of the disk and outlet pipe varies, a sequence of water expressions is provided.
摘要翻译: 描述了一种输水装置,其包括出水管,排出水以提供水显示。 盘相对于出口管定位。 盘和出口管的相对位置移动,使得盘位于出口管内或其上方,以改变离开出口管的水的外观。 随着盘和出口管的相对位置变化,提供了一系列的水表达。
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公开(公告)号:US20140167627A1
公开(公告)日:2014-06-19
申请号:US14108059
申请日:2013-12-16
申请人: Mark Fuller , Jim Doyle , Don Lariviere , Antonio Layon , Scott Winslow , Boris Karpichev
发明人: Mark Fuller , Jim Doyle , Don Lariviere , Antonio Layon , Scott Winslow , Boris Karpichev
IPC分类号: H05B37/02
CPC分类号: F21V23/0407 , F21S2/00 , F21S4/10 , F21S10/00 , F21S10/06 , F21V23/003 , F21V23/02 , F21V23/06 , F21V29/89 , F21V31/00 , F21W2131/401 , F21Y2115/10 , H05B33/0803 , H05B33/0842 , H05B37/029
摘要: A display where lights may be programmed to randomly flash is described. The randomness may be changed by changing the mode of flashing. The lights may extend along strings that are powered by a power supply that may itself be plugged into a socket that had previously served as a light socket. The display may be added to existing displays to enhance existing visual effects. The display may be submerged and the lights may remain upright because of their buoyancy.
摘要翻译: 描述可以将灯编程为随机闪光的显示器。 可以通过改变闪烁模式来改变随机性。 灯可以沿着可能本身插入以前用作灯座的插座的电源供电的串可以延伸。 可以将显示器添加到现有显示器以增强现有的视觉效果。 显示器可能被淹没,并且灯可能因为浮力而保持直立。
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