公开(公告)号：US4799934A

公开(公告)日：1989-01-24

申请号：US114964

申请日：1987-10-30

Applicant: Mu-Ill Lim ,  James S. Anderson

Inventor： Mu-Ill Lim ,  James S. Anderson

IPC: C07C323/36 ,  A61K20060101 ,  A61K8/00 ,  A61K8/41 ,  A61K8/46 ,  A61Q5/06 ,  A61Q5/10 ,  C07C20060101 ,  C07C67/00 ,  C07C313/00 ,  C07C315/02 ,  C07C317/00 ,  C07C317/36 ,  C07C323/37 ,  C09B20060101 ,  C09B49/02 ,  C09B49/04 ,  C09B51/00 ,  C09B67/30 ,  D06P20060101 ,  A61K7/13 ,  C07C149/42

CPC classification number: A61K8/418 ,  A61K8/46 ,  A61Q5/065

Abstract: Novel sulfur containing nitroamino benzene dyes of formula: ##STR1## and salts thereof wherein (a) R.sub.1 and R.sub.2 are the same or different and are selected from the group consisting of alkyl, hydroxyalkyl, polyhydroxyalky, aminoalkyl, monoalkylamioalkyl and dialkylaminoalkyl, wherein(b) n is 0, 1 or 2, and wherein(c) the group ##STR2## occupies a position that is meta or para to the group-NHR.sub.1 ; a process for synthesizing these compounds and their use as direct dyeing hair dyes are being disclosed.

公开(公告)号：US20100125133A1

公开(公告)日：2010-05-20

申请号：US12685738

申请日：2010-01-12

Applicant: Eduardo Torres ,  Laurent D. Kieken ,  Patrick D. Moore ,  Dominick J. Valenti ,  Robert L. Mahaffey ,  Cecile Pasquier ,  Manuela Javet ,  Mu-ill Lim ,  Eugene Steven Sadlowski ,  Mark Robert Sivik ,  Kevin Lee Kott ,  Keith Homer Baker

Inventor： Eduardo Torres ,  Laurent D. Kieken ,  Patrick D. Moore ,  Dominick J. Valenti ,  Robert L. Mahaffey ,  Cecile Pasquier ,  Manuela Javet ,  Mu-ill Lim ,  Eugene Steven Sadlowski ,  Mark Robert Sivik ,  Kevin Lee Kott ,  Keith Homer Baker

IPC: C09B29/01

CPC classification number: C11D3/40 ,  C09B44/20 ,  C11D1/146 ,  C11D1/22 ,  C11D1/29 ,  C11D1/72 ,  C11D1/75 ,  C11D1/83 ,  C11D3/42

Abstract: The present invention relates to thiazolium dyes, laundry care compositions comprising one or more thiazolium dyes, processes of making such dyes and laundry care compositions and methods of using same. The dyes, compositions and methods of the present invention are advantageous in providing improved hueing of fabric, including whitening of white fabric, while avoiding significant build up of bluing dyes on the fabric.

Abstract translation: 本发明涉及噻唑鎓染料，包含一种或多种噻唑鎓染料的洗衣护理组合物，制备这种染料的方法和洗衣护理组合物及其使用方法。 本发明的染料，组合物和方法有利于提供改善的织物色调，包括白色织物的白化，同时避免在织物上显着地形成蓝色染料。

公开(公告)号：US20090282622A1

公开(公告)日：2009-11-19

申请号：US12463761

申请日：2009-05-11

Applicant: Richard Marc Dahlgren ,  William David Laidig ,  Mu-ill Lim ,  Bryan Patrick Murphy ,  Guiru Zhang

Inventor： Richard Marc Dahlgren ,  William David Laidig ,  Mu-ill Lim ,  Bryan Patrick Murphy ,  Guiru Zhang

IPC: A61K8/49 ,  C07D231/46 ,  C07D231/38 ,  C07D401/02

CPC classification number: C07D231/38 ,  A61K8/494 ,  A61Q5/10 ,  C07D498/04

Abstract: Compositions for the oxidative dyeing of keratin fibers, comprising a medium suitable for dyeing and at least one 3-substituted pyrazole keratin dyeing compound and derivatives thereof. A method for oxidative dyeing of keratin fibers, comprising applying such compositions in the presence of an oxidizing agent, for a period sufficient to develop the desired coloration.

Abstract translation: 用于角蛋白纤维氧化染色的组合物，包括适于染色的培养基和至少一种3-取代的吡唑角蛋白染色化合物及其衍生物。 一种角蛋白纤维的氧化染色方法，包括在氧化剂存在下将这些组合物施用足以产生所需着色的时间。

公开(公告)号：US07070630B2

公开(公告)日：2006-07-04

申请号：US10837852

申请日：2004-05-03

Applicant: Mu-Ill Lim ,  Yuh-Guo Pan

Inventor： Mu-Ill Lim ,  Yuh-Guo Pan

IPC: A61K7/13

CPC classification number: C07D213/74 ,  A61K8/415 ,  A61K8/4926 ,  A61K8/494 ,  A61Q5/10 ,  C07C215/80 ,  C07D231/12 ,  C07D233/56 ,  C07D249/08 ,  C07D295/135

Abstract: Primary intermediates for hair coloring compositions for oxidative dyeing of hair are compounds of the formula (1): wherein R1 and R2 are each independently selected from hydrogen atoms, a C1 to C5 alkyl or hydroxyalkyl group, or R1 and R2 together with the nitrogen atom to which they are attached form a 5 or 6 member cyclic ring optionally containing one or more additional atoms selected from O, N or S atoms, and n is equal to 1 or 2, with the proviso that when n is equal to 2 only one of R1 and R2 may be hydrogen.

Abstract translation: 用于头发氧化染色的染发组合物的主要中间体是式（1）的化合物：其中R 1和R 2各自独立地选自氢原子，C C 1至C 5烷基或羟基烷基或R 1和R 2与氮原子一起与 它们连接成5或6元环，任选地含有一个或多个选自O，N或S原子的另外的原子，n等于1或2，条件是当n等于2时，R中只有一个 ＆lt; 1＆gt;和＆lt; R＆gt; 2＆gt;可以是氢。

公开(公告)号：US06951574B2

公开(公告)日：2005-10-04

申请号：US10889269

申请日：2004-07-12

Applicant: Mu-Ill Lim ,  Yuh-Guo Pan

Inventor： Mu-Ill Lim ,  Yuh-Guo Pan

IPC: C07D295/12 ,  A61K8/00 ,  A61K8/30 ,  A61K8/33 ,  A61K8/41 ,  A61K8/49 ,  A61Q5/10 ,  C07B61/00 ,  C07C209/36 ,  C07C211/51 ,  C07C213/08 ,  C07C215/14 ,  C07C217/58 ,  C07C217/84 ,  C07D233/61 ,  C07D295/135 ,  C07D521/00 ,  D06P3/08 ,  A61K7/13

CPC classification number: C07D295/135 ,  A61K8/411 ,  A61K8/49 ,  A61K8/4906 ,  A61K8/4913 ,  A61K8/4926 ,  A61K8/494 ,  A61K8/4973 ,  A61K8/4986 ,  A61Q5/10 ,  C07C211/51 ,  C07C215/14 ,  C07C217/58 ,  C07C217/84 ,  C07D231/12 ,  C07D233/56 ,  C07D249/08

Abstract: Primary intermediates for hair coloring compositions for oxidative dyeing of hair are compounds of the formula (1): where R1 and R2 are each individually selected from a hydrogen atom, a C1 to C3 alkyl group, a C1 to C5 mono or dihydroxyalkyl group; phenyl or benzyl optionally substituted with an alkoxy group, or R1 and R2 together with the nitrogen atom to which they are attached form a piperazine, piperidine, imidazole, or morpholine ring.

Abstract translation: 用于头发氧化染色的染发组合物的主要中间体是式（1）的化合物：其中R 1和R 2各自独立地选自氢原子， C 1至C 3烷基，C 1至C 5单或二羟基烷基; 任选被烷氧基取代的苯基或苄基，或R 1和R 2与它们所连接的氮原子一起形成哌嗪，哌啶，咪唑或吗啉 环。

公开(公告)号：US20050193502A1

公开(公告)日：2005-09-08

申请号：US11040950

申请日：2005-01-21

Applicant: Bryan Murphy ,  Robert Glenn ,  Mu-Ill Lim ,  John Gardlik ,  Stevan Jones ,  William Laidig ,  John Shaffer

Inventor： Bryan Murphy ,  Robert Glenn ,  Mu-Ill Lim ,  John Gardlik ,  Stevan Jones ,  William Laidig ,  John Shaffer

IPC: A61K8/49 ,  A61Q5/10 ,  A61K7/13

CPC classification number: A61K8/4986 ,  A61K8/49 ,  A61K8/4913 ,  A61K8/4946 ,  A61K8/4973 ,  A61Q5/10

Abstract: Bicyclic fused 5-5 heteroaromatic keratin dyeing compounds with two or three heteroatoms. This invention further relates to a composition for the oxidative dyeing of keratin fibers, comprising a medium suitable for dyeing and one or more bicyclic fused 5-5 heteroaromatic keratin dyeing compounds with two or three heteroatoms. This invention further relates to a method for oxidative dyeing of keratin fibers, comprising applying such compositions in the presence of an oxidizing agent, for a period sufficient to develop the desired coloration.

Abstract translation: 双环稠合5-5杂芳族角蛋白染色化合物与两个或三个杂原子。 本发明还涉及一种用于角蛋白纤维氧化染色的组合物，其包含适于染色的培养基和一种或多种具有两个或三个杂原子的双环稠合的5-5杂芳族角蛋白染色化合物。 本发明还涉及一种角蛋白纤维的氧化染色方法，包括在氧化剂存在下将这些组合物施用足以产生所需着色的时间。

公开(公告)号：US06916347B2

公开(公告)日：2005-07-12

申请号：US10838709

申请日：2004-05-04

Applicant: Mu-Ill Lim ,  Yuh-Guo Pan

Inventor： Mu-Ill Lim ,  Yuh-Guo Pan

IPC: C07D295/12 ,  A61K8/00 ,  A61K8/33 ,  A61K8/41 ,  A61K8/49 ,  A61Q5/10 ,  C07B61/00 ,  C07C213/02 ,  C07C215/80 ,  C07C215/82 ,  C07D213/04 ,  C07D213/74 ,  C07D233/06 ,  C07D295/135 ,  C07D521/00 ,  D06P3/08 ,  A61K7/13

CPC classification number: C07D213/74 ,  A61K8/415 ,  A61K8/4926 ,  A61K8/494 ,  A61K8/4946 ,  A61Q5/10 ,  C07C215/80 ,  C07D231/12 ,  C07D233/56 ,  C07D249/08 ,  C07D295/135

Abstract: Primary intermediates for hair coloring compositions for oxidative dyeing of hair are compounds of the formula (1): where R1 and R2 are each individually selected from a hydrogen atom, a C1 to C3 alkyl group, a C1 to C5 mono or dihydroxyalkyl group, phenyl or benzyl optionally substituted with an alkoxy group, or R1 and R2 together with the nitrogen atom to which they are attached form a piperazine, piperidine, imidazole, or morpholine ring.

Abstract translation: 用于头发氧化染色的染发组合物的主要中间体是式（1）的化合物：其中R 1和R 2各自独立地选自氢原子， C 1至C 3烷基，C 1至C 5单或二羟基烷基，苯基或苄基 任选被烷氧基取代，或R 1和R 2与它们所连接的氮原子一起形成哌嗪，哌啶，咪唑或吗啉环。

公开(公告)号：US06887280B2

公开(公告)日：2005-05-03

申请号：US10090377

申请日：2002-03-04

Applicant: Mu-Ill Lim ,  Yuh-Guo Pan ,  Sabina Burdzovic

Inventor： Mu-Ill Lim ,  Yuh-Guo Pan ,  Sabina Burdzovic

IPC: A61K8/00 ,  A61K8/41 ,  A61K8/49 ,  A61Q5/10 ,  A61K7/13

CPC classification number: A61K8/494 ,  A61K8/411 ,  A61K8/4926 ,  A61Q5/10

Abstract: Novel compositions for use in oxidative hair coloring compositions are provided. The compositions comprise one or more oxidative hair coloring N-aryl-m-phenyldiamine derivatives as couplers and one or more diaminopyrazole primary intermediates in combination.

Abstract translation: 提供了用于氧化性染发组合物的新型组合物。 组合物包含一种或多种氧化性着色的N-芳基-m-苯基二胺衍生物作为成色剂和一种或多种二氨基吡唑主要中间体的组合。

公开(公告)号：US06855174B2

公开(公告)日：2005-02-15

申请号：US10838493

申请日：2004-05-04

Applicant: Mu-Ill Lim ,  Yuh-Guo Pan ,  Gottfried Wenke

Inventor： Mu-Ill Lim ,  Yuh-Guo Pan ,  Gottfried Wenke

IPC: C07D295/08 ,  A61K8/00 ,  A61K8/33 ,  A61K8/41 ,  A61K8/49 ,  A61Q5/10 ,  C07C209/12 ,  C07C217/84 ,  C07D233/60 ,  A61K7/13

CPC classification number: C07C217/84 ,  A61K8/415 ,  A61K8/416 ,  A61K8/49 ,  A61K8/4906 ,  A61K8/4913 ,  A61K8/4926 ,  A61K8/494 ,  A61Q5/10 ,  C07C2601/14

Abstract: Couplers for hair coloring compositions for oxidative dyeing of hair are compounds of the formula (1): wherein X is selected from halogen and R5SO4 where the halogen is preferably Cl, Br or I; R, R1 and R2 are each individually selected from C1 to C22 alkyl and C1 to C22 mono or dihydroxyalkyl, or two of R, R1 and R2 together with the nitrogen atom to which they are attached form a C3 to C6 saturated or unsaturated ring optionally containing in the ring one or more additional hetero atoms selected from O, S and N atoms; R3 and R4 are each individually selected from C1 to C6 alkyl, C1 to C6 hydroxyalkyl, C1 to C6 alkoxy, C1 to C6 aminoalkyl or R3 and R4 together form a C1 to C5 alkylene group; and R5 is selected from C1 to C22 alkyl and C1 to C22 mono or dihydroxyalkyl.

Abstract translation: 用于头发氧化染色的染发组合物的成色剂是式（1）的化合物：其中X选自卤素和R 5 SO 4，其中卤素优选为Cl，Br或I; R 1，R 2和R 2各自独立地选自C 1至C 22烷基和C 1至C 22单或二羟基烷基，或者R 1，R 2和R 2中的两个与它们的氮原子一起 连接形成任选地在环中含有一个或多个选自O，S和N原子的另外的杂原子的C 3至C 6饱和或不饱和环; R 3和R 4各自独立地选自C 1至C 6烷基，C 1至C 6羟基烷基，C 1至C 6烷氧基，C 1至C 6氨基烷基或R 3和R 4一起形成C 1至C 5亚烷基 组; 并且R 5选自C 1至C 22烷基和C 1至C 22单或二羟基烷基。

公开(公告)号：US06838561B2

公开(公告)日：2005-01-04

申请号：US10052741

申请日：2002-01-18

Applicant: Mu-Ill Lim ,  Yuh-Guo Pan

Inventor： Mu-Ill Lim ,  Yuh-Guo Pan

IPC: C07D295/12 ,  A61K8/00 ,  A61K8/34 ,  A61K8/41 ,  A61K8/49 ,  A61Q5/10 ,  C07C213/02 ,  C07C215/14 ,  C07C215/76 ,  C07C215/80 ,  C07C217/58 ,  C07C217/84 ,  C07D211/56 ,  C07D295/135 ,  D06P3/08 ,  C07C211/27

CPC classification number: C07D295/135 ,  A61K8/347 ,  A61K8/415 ,  A61K8/4926 ,  A61K8/4953 ,  A61Q5/10 ,  C07C215/14 ,  C07C215/76 ,  C07C217/58 ,  C07C217/84

Abstract: Primary intermediates for hair coloring compositions for oxidative dyeing of hair are compounds of the formula (1): where R1, and R2 are each individually selected from a hydrogen atom, a C1 to C3 alkyl group, a C1 to C5 mono or dihydroxyalkyl group; phenyl or benzyl optionally substituted with an alkoxy group, or R1 and R2 together with the nitrogen atom to which they are attached form a piperazine, piperidine, imidazole, or morpholine ring.

Abstract translation: 用于头发氧化染色的染发组合物的主要中间体是式（1）的化合物：其中R1和R2各自独立地选自氢原子，C1至C3烷基，C1至C5单或二羟基烷基; 任选被烷氧基取代的苯基或苄基，或者R 1和R 2与它们所连接的氮原子一起形成哌嗪，哌啶，咪唑或吗啉环。