公开(公告)号：US20230162962A1

公开(公告)日：2023-05-25

申请号：US17989415

申请日：2022-11-17

Applicant: PerkinElmer Health Sciences, Inc. ,  PerkinElmer Health Sciences Canada, Inc.

Inventor： Tsung-Chi Chen ,  Hamid Badiei ,  Thomas White ,  Sergey Rakov ,  Adam J. Patkin

IPC: H01J49/06 ,  H01J49/10 ,  H01J49/34 ,  G01N30/72

CPC classification number: H01J49/061 ,  H01J49/10 ,  H01J49/067 ,  H01J49/34 ,  G01N30/7206

Abstract: Provided are ion detectors and systems that may employ such ion detectors such as mass spectrometers and other instruments. The ion detectors include a deflector that serves to generate an electric field with designed shape and strength that causes the ions passing into the detector to move along a deflection path. By selectively deflecting the charged ions from an initial propagation axis, the deflector effectively removes unwanted neutral particles from the ion path and reduces background in the resulting spectra.

公开(公告)号：US20220232691A1

公开(公告)日：2022-07-21

申请号：US17152507

申请日：2021-01-19

Applicant: PerkinElmer Health Sciences Canada, Inc.

Inventor： Tak Shun Cheung ,  Chui Ha Cindy Wong ,  William Fisher ,  Hamid R. Badiei

IPC: H05H1/46

Abstract: An ICP torch includes an injector tube defining an injector flow passage to receive a flow of a sample fluid, an intermediate tube disposed about the injector tube, a plasma tube disposed about the intermediate tube, and an induction coil disposed about the plasma tube. An auxiliary gas passage is defined between the injector tube and the intermediate tube to receive a flow of an auxiliary gas. A plasma gas passage is defined between the intermediate tube and the plasma tube to receive a flow of a plasma gas. The induction coil can produce a plasma proximate a torch distal end. The induction coil extends axially from a coil proximal end to a coil distal end proximate the torch distal end. The plasma tube includes an outlet opening proximate the torch distal end. The outlet opening is at least partially coincident with or axially inset from the coil distal end.

公开(公告)号：US11315778B2

公开(公告)日：2022-04-26

申请号：US17025430

申请日：2020-09-18

Applicant: PERKINELMER HEALTH SCIENCES CANADA, INC.

Inventor： Chady Stephan ,  Hamid Badiei ,  Serguei Savtchenko ,  Samad Bazargan

IPC: H01J49/00 ,  H01J49/10 ,  G01N30/72 ,  H01J49/04 ,  H01J49/16

Abstract: Devices, systems and methods including a spray chamber are described. In certain examples, the spray chamber may be configured with an outer chamber configured to provide tangential gas flows. In other instances, an inner tube can be positioned within the outer chamber and may comprise a plurality of microchannels. In some examples, the outer chamber may comprise dual gas inlet ports. In some instances, the spray chamber may be configured to provide tangential gas flow and laminar gas flows to prevent droplet formation on surfaces of the spray chamber. Optical emission devices, optical absorption devices and mass spectrometers using the spray chamber are also described.

公开(公告)号：US11183379B2

公开(公告)日：2021-11-23

申请号：US16835966

申请日：2020-03-31

Applicant: PERKINELMER HEALTH SCIENCES CANADA, INC.

Inventor： Pritesh Patel

IPC: H01J49/10 ,  H05H1/30 ,  H01J49/04 ,  H01J49/34

Abstract: Methods and systems that can use a gas comprising a nitrogen center that is introduced upstream of a plasma sustained in a torch are described. In some configurations, the gas comprising the nitrogen center can be introduced as a gas upstream of the plasma and through a sample introduction device. Mass spectrometers and optical emission systems that can use the gas comprising the nitrogen center are also described.

公开(公告)号：US10930487B2

公开(公告)日：2021-02-23

申请号：US16536855

申请日：2019-08-09

Applicant: PERKINELMER HEALTH SCIENCES CANADA, INC.

Inventor： Hamid Badiei ,  Samad Bazargan

IPC: H01J49/06

Abstract: Certain configurations of devices are described herein that include a DC multipole that is effective to doubly bend the ions in an entering particle beam. In some instances, the devices include a first multipole configured to provide a DC electric field effective to direct first ions of an entering particle beam along a first internal trajectory at an angle different from the entry trajectory of the particle beam. The first multipole may also be configured to direct the ions in the first multipole along a second internal trajectory that is different than the angle of the first internal trajectory of the particle beam.

公开(公告)号：US20200343083A1

公开(公告)日：2020-10-29

申请号：US16835966

申请日：2020-03-31

Applicant: PERKINELMER HEALTH SCIENCES CANADA, INC.

Inventor： Pritesh Patel

IPC: H01J49/10 ,  H01J49/34 ,  H01J49/04 ,  H05H1/30

Abstract: Methods and systems that can use a gas comprising a nitrogen center that is introduced upstream of a plasma sustained in a torch are described. In some configurations, the gas comprising the nitrogen center can be introduced as a gas upstream of the plasma and through a sample introduction device. Mass spectrometers and optical emission systems that can use the gas comprising the nitrogen center are also described.

公开(公告)号：US10658168B2

公开(公告)日：2020-05-19

申请号：US15970517

申请日：2018-05-03

Applicant: PERKINELMER HEALTH SCIENCES CANADA INC.

Inventor： Frenny Kaushal ,  Gholamreza Javahery ,  Lisa Cousins ,  Charles Jolliffe

IPC: H01J49/42 ,  H01J49/16 ,  H01J49/06

Abstract: An ionizer includes a probe having multiple coaxially aligned conduits. The conduits may carry liquids, and nebulizing and heating gases at various flow rates and temperatures, for generation of ions from a liquid source. An outermost conduit defines an entrainment region that transports and entrains ions in a gas for a defined distance along the length of the conduits. In embodiments, various voltages may be applied to the multiple conduits to aid in ionization and to guide ions. Depending on the voltages applied to the multiple conduits and electrodes, the ionizer can act as an electrospray, APCI, or APPI source. Further, the ionizer may include a source of photons or a source of corona ionization. Formed ions may be provided to a downstream mass analyser.

公开(公告)号：US20200035475A1

公开(公告)日：2020-01-30

申请号：US16519925

申请日：2019-07-23

Applicant: PerkinElmer Health Sciences Canada, Inc. ,  Perkin Elmer Yuhan Hoesa

Inventor： Chady Stephan ,  Chung Ryu

IPC: H01J49/04

Abstract: Systems and methods for use in introducing samples to an analytical instrument. The systems and methods are adaptable to process either a liquid sample or a gaseous sample, including samples containing particle contaminants, for subsequent analysis using an analytical instrument.

公开(公告)号：US20190355565A1

公开(公告)日：2019-11-21

申请号：US16408680

申请日：2019-05-10

Applicant: PERKINELMER HEALTH SCIENCES CANADA, INC.

Inventor： Mehrnaz Sarrafzadeh ,  Gholamreza Javahery ,  Charles Jolliffe ,  Lisa Cousins

IPC: H01J49/12

Abstract: Certain configurations of plasma discharge chambers and plasma ionization sources comprising a plasma discharge chamber are described. In some examples, the discharge chamber comprises a conductive area and is configured to sustain a plasma discharge within the discharge chamber. In other examples, the discharge chamber comprises at least one inlet configured to receive a plasma gas and at least one outlet configured to provide ionized analyte from the discharge chamber. Systems and methods using the discharge chambers are also described.

公开(公告)号：US20190080893A1

公开(公告)日：2019-03-14

申请号：US16119141

申请日：2018-08-31

Applicant: PERKINELMER HEALTH SCIENCES CANADA, INC.

Inventor： Pritesh Patel ,  Chady Stephan ,  Fadi Abou-Shakra

IPC: H01J49/02 ,  H01J49/06 ,  H01J49/10 ,  H01J49/00

Abstract: Certain configurations described herein are directed to mass spectrometer systems that can use a gas mixture to select and/or detect ions. In some instances, the gas mixture can be used in both a collision mode and in a reaction mode to provide improved detection limits using the same gas mixture.