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52 条记录 (耗时 0.02 秒)

    Electronic pipettor
    21.
    发明授权
    Electronic pipettor 有权
    电子移液器

    公开(公告)号：US07540205B2

    公开(公告)日：2009-06-02

    申请号：US11856231

    申请日：2007-09-17

    申请人： Gary E. Nelson ,  George P. Kalmakis ,  Joel Novak ,  Kenneth Steiner ,  Jonathon Finger ,  Richard Cote

    发明人： Gary E. Nelson ,  George P. Kalmakis ,  Joel Novak ,  Kenneth Steiner ,  Jonathon Finger ,  Richard Cote

    IPC分类号： G01N1/00

    CPC分类号： B01L3/0234 ,  B01L2200/0605 ,  B01L2200/087 ,  B01L2200/148

    摘要： A hand-held electronic pipettor is designed particularly to be programmed and operated with one hand for the convenience of the user. It uses a capacitance touchpad control for programming, and a separate run button for the operating mode. Internal components are located so that the center of gravity of the pipettor is located within the palm of the user. Flash memory stores an empirically derived table that correlates aspiration volume to motor steps and a separate empirically derived table the correlates dispensing volumes to motor steps.

    摘要翻译： 手持式电子移液器特别设计为一方面进行编程和操作，方便用户使用。 它使用电容式触摸板控件进行编程，另外还有一个运行模式的运行按钮。 内部部件被定位成使得移液器的重心位于使用者的手掌内。 闪存存储经验导出的表，其将抽吸体积与运动步骤相关联，以及单独的经验派生表将分配体积与运动步骤相关联。

    LOCKING PIPETTE TIP AND MOUNTING SHAFT
    23.
    发明申请
    LOCKING PIPETTE TIP AND MOUNTING SHAFT 有权

    公开(公告)号：US20080286157A1

    公开(公告)日：2008-11-20

    申请号：US11934381

    申请日：2007-11-02

    申请人： Gregory Mathus ,  Terrence Kelly ,  Richard Cote

    发明人： Gregory Mathus ,  Terrence Kelly ,  Richard Cote

    IPC分类号： B01L3/02

    CPC分类号： B01L3/0217 ,  B01L3/0275 ,  B01L3/0279 ,  B01L2200/023 ,  B01L2200/025 ,  B01L2200/0689 ,  B01L2200/087 ,  B01L2300/027 ,  Y10T137/0318 ,  Y10T436/2575

    摘要： In one aspect, the invention relates to a pipette tip mounting shaft configuration and a disposable pipette tip having a matching configuration. The mounting shaft includes a locking section located above a lower sealing section. The locking section has outwardly extending locking lobes located above a stop member and a lower sealing section located below the stop member. In certain embodiments, the diameter of the mounting shaft below the stop member is reduced in order to lessen insertion and ejection forces, which is particularly helpful for hand-held multi-channel pipettors. In these embodiments, the lower sealing section contains either a frustoconical sealing section, or an annular groove and a sealing ring, such as a flouroelastomeric O-ring seal. When the mounting shaft is fully inserted into the collar of the mating disposable pipette tip, the tip locks onto the mounting shaft. The bore of the pipette tip includes a circumferential shelf or shoulder separating its upper collar from the tip sealing area which is located below the circumferential shelf. The tip collar preferably includes a locking ring located at or near the upper opening for the mounting shaft. The dimensions of the collar, and in particular the distance between its circumferential shelf and the locking ring, are selected to match the dimensions of the mounting shaft between the stop member and the upper end of the locking lobes, thus locking the pipette tip in a secure, reliable position and orientation while using ergonomic insertion and ejection forces. The locking lobes preferably include a ramp portion that gently flexes and distorts the pipette tip collar out of round as the mounting shaft is inserted in the pipette tip, rather than stretching the tip collar. The circumferential shelf on the pipette tip between the tip collar and the barrel isolates the sealing area at the upper end of the barrel from distortion, thus facilitating reliable sealing engagement between the lower sealing section of the mounting shaft and the sealing ring in the upper end of the barrel of the pipette tip.

    Hand-held pipette employing voice recognition control
    25.
    发明申请
    Hand-held pipette employing voice recognition control 审中-公开
    手持移液器采用语音识别控制

    公开(公告)号：US20060027033A1

    公开(公告)日：2006-02-09

    申请号：US10903448

    申请日：2004-07-30

    申请人： Richard Cote ,  Robert Zier ,  Craig Weiss ,  William Frazier

    发明人： Richard Cote ,  Robert Zier ,  Craig Weiss ,  William Frazier

    IPC分类号： B01L3/02

    CPC分类号： B01L3/0227 ,  B01L3/0237

    摘要： A hand-held pipette is disclosed including a pipette tip, a piston, and a voice recognition and control system. The pipette tip is provided at one end of an elongated enclosure. The piston is received in an opposite end of the elongated enclosure. The piston is adapted for reciprocal movement within at least a portion of the elongated enclosure through a selected first stroke to aspirate a first volume of fluid into the pipette tip and to expel the thus aspirated first volume of fluid out of the pipette tip. The voice recognition and control system is for automatically adjusting the stroke of the piston from the first stroke to a second stroke responsive to voice commands such that a second volume of fluid may be aspirated into the pipette tip and the thus aspirated second volume of fluid may be expelled out of the pipette tip.

    摘要翻译： 公开了一种手持式移液器，其包括吸头，活塞和语音识别和控制系统。 移液管尖端设置在细长外壳的一端。 活塞被容纳在细长外壳的相对端。 活塞适于在细长外壳的至少一部分内通过所选择的第一冲程往复运动，以将第一体积的流体吸入移液管吸头中，并将由此吸出的第一体积的流体排出移液管尖端。 语音识别和控制系统用于响应于语音命令自动地将活塞的冲程从第一冲程调整到第二冲程，使得第二体积的流体可以被吸入移液管尖端，并且由此吸出的第二体积的流体可以 被排出移液器吸头。

    Method of using a disposable pipette tip
    26.
    发明申请
    Method of using a disposable pipette tip 有权
    使用一次性吸头的方法

    公开(公告)号：US20130306155A1

    公开(公告)日：2013-11-21

    申请号：US13952731

    申请日：2013-07-29

    申请人： Gregory Mathus ,  Terrance Kelly ,  Richard Cote

    发明人： Gregory Mathus ,  Terrance Kelly ,  Richard Cote

    IPC分类号： B01L3/02

    CPC分类号： B01L3/0217 ,  B01L3/0275 ,  B01L3/0279 ,  B01L2200/023 ,  B01L2200/025 ,  B01L2200/0689 ,  B01L2200/087 ,  B01L2300/027 ,  Y10T137/0318 ,  Y10T436/2575

    摘要： The pipetting method is directed to mounting and ejecting a disposable pipette tip. The pipetting system has one or more tip mounting shafts with an upper locking section and a lower sealing section. The upper locking section has outwardly extending lobes spaced around the mounting shaft and located above a stop member. The lower sealing section on the tip mounting shaft is located below the stop. As the mounting shaft is inserted into the collar of the disposable pipette, the collar distorts out of round and engages the lobes on the upper locking section of the tip mounting shaft. Contemporaneously, the lower sealing section of the mounting shaft seals against the barrel of the disposable pipette tip.

    摘要翻译： 移液方法涉及安装和喷射一次性吸头。 移液系统具有一个或多个具有上部锁定部分和下部密封部分的尖端安装轴。 上锁定部分具有围绕安装轴间隔开并位于止动件上方的向外延伸的凸角。 刀片安装轴上的下密封部分位于挡块下方。 当安装轴插入到一次性移液管的轴环中时，套环从圆形变形并与尖端安装轴的上部锁定部分上的凸角接合。 同时，安装轴的下密封部分密封在一次性移液管尖端的筒体上。

    CALIBRATION METHODS FOR MULTIPLEXED SENSOR ARRAYS
    28.
    发明申请
    CALIBRATION METHODS FOR MULTIPLEXED SENSOR ARRAYS 审中-公开
    多传感器阵列校准方法

    公开(公告)号：US20100204062A1

    公开(公告)日：2010-08-12

    申请号：US12614239

    申请日：2009-11-06

    申请人： Mark Thompson ,  Richard Roberts ,  Richard Cote ,  Chongwu Zhou

    发明人： Mark Thompson ,  Richard Roberts ,  Richard Cote ,  Chongwu Zhou

    IPC分类号： C40B40/06 ,  C40B40/10 ,  G01N35/00

    CPC分类号： B82Y15/00 ,  B82Y35/00 ,  G01N27/4146 ,  G01N33/54373 ,  G01N35/00693

    摘要： The present invention relates to the calibration of devices using a secondary binding agent or reference material. In one embodiment, the present invention provides a method of calibrating a nanosensor by providing a nanosensor comprising an analyte binder attached to a reference binder, extracting a calibration curve from binding a reference material to the reference binder, and calibrating the nanosensor by using the calibration curve to correct for device variation.

    摘要翻译： 本发明涉及使用二次结合剂或参考物质的装置的校准。 在一个实施方案中，本发明提供了一种校准纳米传感器的方法，该方法通过提供纳米传感器，该纳米传感器包括附着于参考粘合剂的分析物粘合剂，从校正曲线结合参考物质到参考粘合剂，以及通过使用校准来校准纳米传感器 曲线以校正设备变化。

    Common Signal Eliminator From a Stereo Source
    30.
    发明申请
    Common Signal Eliminator From a Stereo Source 审中-公开
    来自立体声源的常见信号消除器

    公开(公告)号：US20080285763A1

    公开(公告)日：2008-11-20

    申请号：US10588987

    申请日：2004-12-06

    申请人： Richard Cote ,  Simon Roy

    发明人： Richard Cote ,  Simon Roy

    IPC分类号： H04R5/00

    CPC分类号： H04S3/00

    摘要： To increase the stereophonic potential of an ordinary stereo source, a device (20) eliminates the common signals from a stereo source. The device is installed in relation to four loudspeakers, two primary (38, 40) and two secondary (42, 44), and it includes a stereo input (34, 36) and an electric circuit that links the two secondary loudspeakers. The primary loudspeakers reproduce unaltered stereo signals and the secondary loudspeakers reproduce altered signals where (by hand: when) the circuit has eliminated the common signals from the two channels of the primary stereo source. Since all “mono” components of the sound [by hand: same amplitude, same frequency] have been eliminated from the secondary outputs, we obtain a “purely stereo” source. An additional channel (45) can be added in order to reproduce the common components of the stereo source.

    摘要翻译： 为了增加普通立体声源的立体声电位，设备（20）消除了来自立体声源的公共信号。 该装置相对于四个扬声器，两个主要（38,40）和两个次要（42,44）安装，并且其包括立体声输入（3​​4,36）和连接两个二次扬声器的电路。 主扬声器再现未改变的立体声信号，次级扬声器再​​现改变的信号，其中（手动：何时）电路已经消除了来自主立体声源的两个声道的公共信号。 由于二次输出中已经消除了声音[手动相同的幅度，相同频率]的所有“单声道”分量，所以我们获得了一个“纯立体声”源。 可以添加附加通道（45）以便再现立体声源的公共部件。