公开(公告)号：US4986754A

公开(公告)日：1991-01-22

申请号：US546903

申请日：1990-07-02

申请人： Tiang-shing Chang ,  Lisa N. W. Marchese

发明人： Tiang-shing Chang ,  Lisa N. W. Marchese

IPC分类号： C08K5/101

CPC分类号： C08K5/101

摘要： A nonshrinkable, thermoplastic and injectable endodontic filling composition. The composition is a mixture of transpolyisoprene, either naturally produced as balata or gutta percha, or synthesized from isoprene, and a liquid castor ester platicizer. Alternatively, the mixture comprises transpolyisoprene, a liquid castor ester plasticizer and a liquid castor oil or dimethyl silcon fluid lubricant. The mixture is preferably a combination of the transpolyisoprene, the liquid castor ester plasticizer and the liquid castor oil or liquid dimethyl silicon fluid lubricant or both. The composition is compounded to form a highly thermoplastic material which is injectable at a clinically acceptable temperature with a manually operated injection system without shrinkage of the composition after placement in a dental root canal.

摘要翻译： 一种无毒，热塑和可注射的牙髓填充组合物。 该组合物是透性聚异戊二烯的混合物，其自然产生为巴拉酸或古丁酸，或由异戊二烯合成，以及液体蓖麻酯矫顽剂。 或者，该混合物包括透性聚异戊二烯，液体蓖麻油酯增塑剂和液体蓖麻油或二甲基硅烷润滑剂。 混合物优选是透花生四烯，液体蓖麻酯增塑剂和液体蓖麻油或液体二甲基硅液体润滑剂或两者的组合。 将组合物复合以形成高度热塑性材料，其可以在临床可接受的温度下用手动操作的注射系统注射，而不会在置于牙根管内之后组合物收缩。

公开(公告)号：US4952508A

公开(公告)日：1990-08-28

申请号：US64841

申请日：1987-06-19

申请人： Shing Chang ,  Hing C. Wong ,  Vaughan P. Wittman

发明人： Shing Chang ,  Hing C. Wong ,  Vaughan P. Wittman

IPC分类号： C12N1/21 ,  C12N9/86 ,  C12N15/62 ,  C12N15/75

CPC分类号： C12N9/86 ,  C12N15/625 ,  C12N15/75 ,  C07K2319/02 ,  C07K2319/036 ,  C07K2319/61 ,  C07K2319/75

摘要： A method and a cloning vector are described for the controlled accumulation of cloned heterologous gene products in Bacillus subtilis. The cloning vector is capable of being replicated in B. subtilis and includes the heterologous gene located and oriented such as to be under the control of an operator, promoter, and ribosome binding site sequence. The gene codes for a protein which is under the control of a transport mechanism by which the protein is secreted by the B. subtilis. The gene product is recovered from the growth medium for the B. subtilis. The cloning vector is also capable of similar use in other bacteria such as E. coli.

摘要翻译： 描述了克隆的异源基因产物在枯草芽孢杆菌中的受控积累的方法和克隆载体。 克隆载体能够在枯草芽孢杆菌中复制，并且包括位于和定向的异源基因，以便在操纵子，启动子和核糖体结合位点序列的控制下。 该基因编码一种蛋白质，其由蛋白质被枯草芽孢杆菌分泌的转运机制控制。 从枯草芽孢杆菌的生长培养基中回收基因产物。 克隆载体也能够在其他细菌如大肠杆菌中类似地使用。

公开(公告)号：US4950697A

公开(公告)日：1990-08-21

申请号：US244291

申请日：1988-09-15

申请人： Tiang-shing Chang ,  Lisa N. Weddle Marchese

发明人： Tiang-shing Chang ,  Lisa N. Weddle Marchese

IPC分类号： C08K5/101

CPC分类号： C08K5/101

摘要： A nonshrinkable, thermoplastic and injectable endodontic filling composition. The composition is a mixture of transpolyisoprene, either naturally produced as balata or gutta percha, or synthesized from isoprene, and a liquid castor ester platicizer. Alternatively, the mixture comprises transpolyisoprene, a liquid castor ester platicizer and castor oil or dimethyl silicon fluid lubricant. The mixture is preferably a combination of the transpolyisoprene, the liquid castor ester plasticizer and the liquid castor oil or dimethyl silicon fluid lubricant or both. The composition is compounded to form a highly thermoplastic material which is injectable at a clinically acceptable temperature with a manually operated injection system without shrinkage of the composition after placement in a dental root canal.

摘要翻译： 一种无毒，热塑和可注射的牙髓填充组合物。 该组合物是透性聚异戊二烯的混合物，其自然产生为巴拉酸或古丁酸，或由异戊二烯合成，以及液体蓖麻酯矫顽剂。 或者，该混合物包括透花生四烯，液体蓖麻酯矫顽剂和蓖麻油或二甲基硅液润滑剂。 混合物优选是透花生四烯，液体蓖麻酯增塑剂和液体蓖麻油或二甲基硅液体润滑剂或两者的组合。 将组合物复合以形成高度热塑性材料，其可以在临床可接受的温度下用手动操作的注射系统注射，而不会在置于牙根管内之后组合物收缩。

公开(公告)号：US4910141A

公开(公告)日：1990-03-20

申请号：US717331

申请日：1985-03-29

申请人： Hing C. Wong ,  Shing Chang

发明人： Hing C. Wong ,  Shing Chang

IPC分类号： C07K14/55 ,  C12N9/86 ,  C12N15/67 ,  C12N15/70

CPC分类号： C12N15/67 ,  C07K14/55 ,  C12N15/70 ,  C12N9/86

摘要： The invention concerns a method for extending the half-life of mRNAs. The half-life extension is conferred upon the mRNA by a co-transcribed positive retroregulatory element which is ligated to the 3' end of the DNA sequence encoding the RNA. RNAs having an extended half-life conferred by a co-transcribed positive retroregulatory element are also claimed.

公开(公告)号：US4865974A

公开(公告)日：1989-09-12

申请号：US860330

申请日：1986-05-06

申请人： Arie Ben-Bassat ,  Keith A. Bauer ,  Shing Chang ,  Sheng-Yung Chang

发明人： Arie Ben-Bassat ,  Keith A. Bauer ,  Shing Chang ,  Sheng-Yung Chang

IPC分类号： C07K14/415 ,  C07K14/55 ,  C12N1/21 ,  C12N9/48 ,  C12N15/09 ,  C12N15/57 ,  C12N15/70 ,  C12P21/02 ,  C12R1/19

CPC分类号： C12N15/70 ,  C07K14/415 ,  C07K14/55 ,  C12N9/48 ,  C12P21/02 ,  Y10S930/141 ,  Y10S930/30

摘要： Methods for obtaining N-terminal methionine-free proteins involve a novel E. coli methionine amino peptidase. The method is capable of in vitro or in vivo application. For in vivo application, a plasmid-borne DNA encoding the peptide is expressed in a bacterial host.

摘要翻译： 获得N-末端不含甲硫氨酸的蛋白质的方法涉及新型大肠杆菌甲硫氨酸氨基肽酶。 该方法能够在体外或体内应用。 对于体内应用，编码肽的质粒携带DNA在细菌宿主中表达。

公开(公告)号：US4816396A

公开(公告)日：1989-03-28

申请号：US843940

申请日：1986-03-25

申请人： Shing Chang

发明人： Shing Chang

IPC分类号： C07K14/565 ,  C12N9/86 ,  C12N15/62 ,  C12N15/75 ,  C12P21/00 ,  C12N1/20 ,  C12N15/00

CPC分类号： C07K14/565 ,  C12N15/625 ,  C12N15/75 ,  C12N9/86 ,  C07K2319/02 ,  C07K2319/036 ,  C07K2319/61 ,  C07K2319/75 ,  Y10S930/142 ,  Y10S930/30

摘要： The invention discloses a method and cloning vectors useful for the production of cloned heterologous gene products in B. subtilis. Use of the method and vector allows the host to produce the heterologous gene product as a single unfused peptide having no extraneous amino acids attached.

摘要翻译： 本发明公开了一种用于在枯草芽孢杆菌中产生克隆的异源基因产物的方法和克隆载体。 使用该方法和载体允许宿主产生异源基因产物作为单个未附着的无外源氨基酸的未融合肽。

公开(公告)号：US4373036A

公开(公告)日：1983-02-08

申请号：US332890

申请日：1981-12-21

申请人： Tiang-Shing Chang ,  Lucy J. Zientek ,  Arthur Viningauz ,  Marcy L. Scheps

发明人： Tiang-Shing Chang ,  Lucy J. Zientek ,  Arthur Viningauz ,  Marcy L. Scheps

IPC分类号： A61K6/00 ,  C08L1/28 ,  C08L71/02 ,  C09J101/28 ,  C09J129/10 ,  C09J133/02 ,  C09J3/04

CPC分类号： C09J129/10 ,  A61K6/0088 ,  C09J101/284 ,  C09J133/02 ,  C08L1/284 ,  C08L71/02

摘要： A denture fixative composition contains a dentally acceptable excipient and an effective fixative amount of a fixative mixture comprising hydroxypropyl cellulose and at least one partially neutralized alkyl vinyl ether-maleic acid or anhydride copolymer, optionally partly crosslinked, or a partially neutralized, optionally partly crosslinked polyacrylic acid or a precursor combination of the copolymer or polyacrylic acid, neutralizing agents, and optionally crosslinking agents, which is adapted to form the fixative in situ, or polyethylene oxide.

摘要翻译： 义齿固定剂组合物含有牙齿可接受的赋形剂和有效的固定剂量的固定混合物，其包含羟丙基纤维素和至少一种部分中和的烷基乙烯基醚 - 马来酸或酸酐共聚物，任选地部分交联的或部分中和的，任选部分交联的聚丙烯酸 酸或共聚物或聚丙烯酸的前体组合，中和剂和任选的交联剂，其适于原位形成固定剂或聚环氧乙烷。

公开(公告)号：US20100072976A1

公开(公告)日：2010-03-25

申请号：US12497186

申请日：2009-07-02

申请人： Jeng-Tzong Sheu ,  Chen-Chia Chen ,  Yaw-Kuen Li ,  Ko-Shing Chang

发明人： Jeng-Tzong Sheu ,  Chen-Chia Chen ,  Yaw-Kuen Li ,  Ko-Shing Chang

IPC分类号： G01N27/00 ,  H01L29/786 ,  H01L21/28

CPC分类号： G01N33/54373 ,  G01N27/4145

摘要： A sensing element includes a field-effect transistor (FET) with an ultra-thin channel, a reference electrode, a first and a second passivation layer, and a microchannel. The first and the second passivation layer enclose a first and a second portion of the FET, respectively. The microchannel is bonded to the first and the second passivation layer, such that the microchannel is extended across the channel of the ultra-thin channel FET. The ultra-thin channel has a chemically or physically modified surface. When an analyte to be tested passes through the microchannel and is in contact with the modified surface of the ultra-thin channel, it results in changes in the conductance of the ultra-thin channel FET. Trace detection may be conducted on the analyte by observing changes in the conductance. A method for manufacturing the sensing element and a biological detection system employing the sensing element are also provided.

摘要翻译： 感测元件包括具有超薄通道的场效应晶体管（FET），参考电极，第一和第二钝化层以及微通道。 第一和第二钝化层分别包围FET的第一和第二部分。 微通道结合到第一钝化层和第二钝化层，使得微通道跨越超薄沟道FET的沟道延伸。 超薄通道具有化学或物理改性的表面。 当待测试的分析物通过微通道并与超薄通道的改性表面接触时，其导致超薄通道FET的电导的变化。 可通过观察电导率的变化对分析物进行痕量检测。 还提供了用于制造感测元件的方法和使用感测元件的生物检测系统。

公开(公告)号：US20090065296A1

公开(公告)日：2009-03-12

申请号：US11944652

申请日：2007-11-26

申请人： Wen Shing Chang ,  Yu-Hsuan Cho

发明人： Wen Shing Chang ,  Yu-Hsuan Cho

IPC分类号： F01N1/00

CPC分类号： F01N3/2842 ,  F01N13/1872 ,  F01N13/1888

摘要： A fixing device includes a muffler and a catalyst mantle. The muffler is communicated with an exhausting route of an internal combustion engine. The muffler has at least one clapboard to divide inner space thereof for forming a plurality of expanding rooms, which are communicated with each other and configured for guiding waste gas. The catalyst mantle is integrated on the clapboard. The catalyst mantle has an admission terminal and an exhaust terminal communicated with the plurality of expanding rooms. A substrate having catalyst coated thereon is arranged in the catalyst mantle between the admission terminal and the exhaust terminal. At least one block is configured for preventing the substrate sliding to the exhaust terminal and a stopper is formed on the clapboard or an inner wall of the muffler for preventing the substrate sliding to the admission terminal. The fixing device improves the fixing capacity of the substrate, and decreases the manufacturing steps for arranging the catalyst mantle in the muffler.

摘要翻译： 定影装置包括消声器和催化剂罩。 消声器与内燃机的排气路线连通。 消音器具有至少一个隔板，用于分隔其内部空间以形成多个膨胀室，彼此连通并构造成用于引导废气。 催化剂罩集成在隔板上。 催化剂罩具有与多个扩张室连通的进入终端和排气终端。 其上涂覆有催化剂的基板被布置在接纳端子和排气端子之间的催化剂罩中。 至少一个块被构造成用于防止基板滑动到排气端子，并且阻挡件形成在隔板或消音器的内壁上，用于防止基板滑动到入口端子。 定影装置提高了基板的定影能力，并且降低了将消除器中的催化剂罩布置的制造步骤。

公开(公告)号：US20080178582A1

公开(公告)日：2008-07-31

申请号：US11686969

申请日：2007-03-16

申请人： Wen Shing Chang

发明人： Wen Shing Chang

IPC分类号： F01N3/10

CPC分类号： F01N1/14 ,  F01N3/035 ,  F01N13/0097 ,  F01N2230/04

摘要： A catalytic apparatus is used for a motorcycle with an engine. The catalytic apparatus includes an engine exhaust manifold, a silencer, a front exhaust pipe positioned between the engine exhaust manifold and the silencer, a front supply pipe connected to the engine exhaust manifold and configured for supplying secondary air, and at least one catalytic converter positioned in the silencer. A catalyst is coated on an inner wall of the front exhaust pipe. The catalyst receives the secondary air supplied by the front supply pipe to clean engine exhaust gases. Particularly, when the motorcycle is started in a cold state, the present catalytic apparatus can enhance the temperature of the engine exhaust gases, and the at least one catalytic converter can be accelerated to reach its operating temperature.

摘要翻译： 催化装置用于具有发动机的摩托车。 催化装置包括发动机排气歧管，消声器，位于发动机排气歧管和消音器之间的前排气管，连接到发动机排气歧管并构造成用于供应二次空气的前供气​​管，以及至少一个位于 在消声器 催化剂涂覆在前排气管的内壁上。 催化剂接收由前供料管供应的二次空气以清洁发动机排气。 特别地，当摩托车在冷启动时，本催化装置可以提高发动机废气的温度，并且可以加速至少一个催化转化器达到其工作温度。