公开(公告)号：US20160370460A1

公开(公告)日：2016-12-22

申请号：US15180560

申请日：2016-06-13

Applicant: Shu TAKAHASHI ,  Koji MASUDA ,  Masahiro ITOH ,  Yasuhiro NIHEI ,  Takeshi UEDA ,  Takeshi OGAWA ,  Hiroaki TANAKA ,  Shiori OHSUGI

Inventor： Shu TAKAHASHI ,  Koji MASUDA ,  Masahiro ITOH ,  Yasuhiro NIHEI ,  Takeshi UEDA ,  Takeshi OGAWA ,  Hiroaki TANAKA ,  Shiori OHSUGI

IPC: G01S7/483 ,  G01S17/88

CPC classification number: G01S7/483 ,  G01S17/10 ,  G01S17/88 ,  G01S17/89 ,  G01S17/936

Abstract: A sensor includes a light source to emit a pulse light, a light receiver to receive light, emitted from the light source and reflected from an object, a range information acquisition unit to calculate information of a range to the object based on light emission timing at the light source and light reception timing at the light receiver and a speed of the pulse light emitted from the light source, and a pulse controller to control a pulse pattern of the pulse light emitted from the light source based on the range information calculated by the range information acquisition unit.

Abstract translation: 传感器包括发射脉冲光的光源，从光源发射并从物体反射的光接收器的光接收器，范围信息获取单元，基于来自物体的发光定时计算对象的范围的信息 在光接收器处的光源和光接收定时以及从光源发射的脉冲光的速度，以及脉冲控制器，用于基于由光源计算的范围信息来控制从光源发射的脉冲光的脉冲图案 范围信息采集单元。

公开(公告)号：US09371395B2

公开(公告)日：2016-06-21

申请号：US13455021

申请日：2012-04-24

Applicant: Shu Takahashi ,  Tatsuji Matsuoka ,  Kenji Murakami ,  Takeshi Takizawa ,  Kenji Hirotani ,  Atsushi Urano ,  Keisuke Fukuchi ,  Mitsuhiro Yazawa

Inventor： Shu Takahashi ,  Tatsuji Matsuoka ,  Kenji Murakami ,  Takeshi Takizawa ,  Kenji Hirotani ,  Atsushi Urano ,  Keisuke Fukuchi ,  Mitsuhiro Yazawa

IPC: C12P21/08 ,  C07K16/00 ,  C07K16/30 ,  C07K16/28 ,  A61K39/395 ,  C07H21/00 ,  C07K16/42

CPC classification number: C07K16/2827 ,  A61K39/39558 ,  A61K45/06 ,  A61K2039/505 ,  C07K16/30 ,  C07K16/42 ,  C07K2317/24 ,  C07K2317/40 ,  C07K2317/73 ,  C07K2317/732 ,  C07K2317/734 ,  C07K2317/92

Abstract: An antibody exhibiting antitumor activity that binds to B7-H3, a functional fragment of the antibody, a pharmaceutical composition that includes the antibody or the functional fragment, methods for making the antibody or the functional fragment, methods for treating a tumor using the antibody or the functional fragment, and polynucleotides encoding the antibody or the functional fragment.

Abstract translation: 显示与B7-H3（抗体的功能片段）结合的抗肿瘤活性的抗体，包含抗体或功能片段的药物组合物，制备抗体或功能片段的方法，使用抗体治疗肿瘤的方法或 功能片段和编码抗体或功能片段的多核苷酸。

公开(公告)号：US07855056B2

公开(公告)日：2010-12-21

申请号：US10548688

申请日：2004-03-09

Applicant: Kimihisa Ichikawa ,  Shu Takahashi ,  Toshinori Agatsuma ,  Keisuke Fukuchi ,  Takehiro Hirai

Inventor： Kimihisa Ichikawa ,  Shu Takahashi ,  Toshinori Agatsuma ,  Keisuke Fukuchi ,  Takehiro Hirai

IPC: G01N33/53

CPC classification number: C07K16/30 ,  C07K2317/732 ,  C12Q1/6886 ,  C12Q2600/136 ,  C12Q2600/158

Abstract: The present invention relates to a method of detecting cancer by use of an oncogene, a method of screening for an active compound useful to treat and/or prevent cancer, and a pharmaceutical composition for treatment and/or prevention of cancer. More specifically, the present invention provides a method of detecting cancer based on the expression of the human oculospanin gene as a marker and a pharmaceutical composition containing an antibody capable of specifically recognizing human oculospanin and having cytotoxic activity against cancer cells.

Abstract translation: 本发明涉及通过使用癌基因检测癌症的方法，筛选用于治疗和/或预防癌症的活性化合物的方法和用于治疗和/或预防癌症的药物组合物。 更具体地，本发明提供了一种基于人oculospanin基因作为标记物的表达和含有能够特异性识别人oculospanin并对癌细胞具有细胞毒性活性的抗体的药物组合物来检测癌症的方法。

公开(公告)号：US20080055449A1

公开(公告)日：2008-03-06

申请号：US11705766

申请日：2007-02-14

Applicant: Masanori Nagase ,  Shu Takahashi ,  Jiro Matsuda ,  Mitsuru Iwata ,  Shinji Uya

Inventor： Masanori Nagase ,  Shu Takahashi ,  Jiro Matsuda ,  Mitsuru Iwata ,  Shinji Uya

IPC: H04N3/14

CPC classification number: H04N5/359 ,  H01L27/14818 ,  H04N5/3728

Abstract: A solid-state imaging device comprises: a semiconductor substrate; a plurality of photoelectric conversion elements formed in a surface portion of the semiconductor substrate in the form of a two-dimensional array so as to comprise a plurality of sets, each comprising a subset of the photoelectric conversion elements arranged in one direction; charge transfer paths each formed at a side portion of the subset of the photoelectric conversion elements to cause a signal charge of the photoelectric conversion elements be read out when a readout pulse is applied and cause the signal charge which has been read out to be transferred when a transfer pulse is applied; and an electrically conductive light shielding film which is laminated on a surface of the semiconductor substrate through an insulating layer and has openings immediately above each of the photoelectric conversion elements.

Abstract translation: 固态成像装置包括：半导体衬底; 多个光电转换元件，形成在二维阵列形式的半导体衬底的表面部分中，以便包括多个集合，每个集合包括沿一个方向布置的光电转换元件的子集; 当施加读出脉冲时，每个形成在光电转换元件的子集的侧部处的电荷传输路径以引起光电转换元件的信号电荷，并且当已经读出的信号电荷被传送时， 施加转移脉冲; 以及通过绝缘层层叠在半导体基板的表面上并且在每个光电转换元件上方具有开口的导电性遮光膜。