公开(公告)号：US20170261611A1

公开(公告)日：2017-09-14

申请号：US15447973

申请日：2017-03-02

Applicant: Shu TAKAHASHI ,  Yasuhiro NIHEI ,  Masahiro ITOH ,  Takeshi OGAWA ,  Hiroaki TANAKA ,  Yoichi ICHIKAWA ,  Koji MASUDA

Inventor： Shu TAKAHASHI ,  Yasuhiro NIHEI ,  Masahiro ITOH ,  Takeshi OGAWA ,  Hiroaki TANAKA ,  Yoichi ICHIKAWA ,  Koji MASUDA

IPC: G01S17/10 ,  G01S17/00 ,  G01S7/484

CPC classification number: G01S17/10 ,  G01S7/4915 ,  G01S17/36 ,  G01S17/89

Abstract: A range finding apparatus includes a light emission unit including a light source and a light source driver, a light detection unit, and circuitry. The light source driver supplies a plurality of drive pulses having different pulse width at different time periods. The light detection unit receives the light emitted from the light emission unit and then reflected from an object. The circuitry calculates a range to the object based on a time difference between one time point when a pulse light is emitted from the light source and another time point when light reflected from the object is received by the light detection unit. One of the drive pulses set with a smaller pulse width is set with a sine wave pattern, and another one of the drive pulses set with a greater pulse width is set with a rectangular wave pattern.

公开(公告)号：US20130078234A1

公开(公告)日：2013-03-28

申请号：US13455021

申请日：2012-04-24

Applicant: Shu Takahashi ,  Tatsuji Matsuoka ,  Kenji Murakami ,  Takeshi Takizawa ,  Kenji Hirotani ,  Atsushi Urano ,  Keisuke Fukuchi ,  Mitsuhiro Yazawa

Inventor： Shu Takahashi ,  Tatsuji Matsuoka ,  Kenji Murakami ,  Takeshi Takizawa ,  Kenji Hirotani ,  Atsushi Urano ,  Keisuke Fukuchi ,  Mitsuhiro Yazawa

IPC: C07K16/42

CPC classification number: C07K16/2827 ,  A61K39/39558 ,  A61K45/06 ,  A61K2039/505 ,  C07K16/30 ,  C07K16/42 ,  C07K2317/24 ,  C07K2317/40 ,  C07K2317/73 ,  C07K2317/732 ,  C07K2317/734 ,  C07K2317/92

Abstract: An antibody exhibiting antitumor activity that binds to B7-H3, a functional fragment of the antibody, a pharmaceutical composition that includes the antibody or the functional fragment, methods for making the antibody or the functional fragment, methods for treating a tumor using the antibody or the functional fragment, and polynucleotides encoding the antibody or the functional fragment.

Abstract translation: 显示与B7-H3（抗体的功能片段）结合的抗肿瘤活性的抗体，包含抗体或功能片段的药物组合物，制备抗体或功能片段的方法，使用抗体治疗肿瘤的方法或 功能片段和编码抗体或功能片段的多核苷酸。

公开(公告)号：US07361340B2

公开(公告)日：2008-04-22

申请号：US11223812

申请日：2005-09-09

Applicant: Kimihasa Ichikawa ,  Shu Takahashi ,  Toshinori Agatsuma ,  Keisuke Fukuchi ,  Takehiro Hirai

Inventor： Kimihasa Ichikawa ,  Shu Takahashi ,  Toshinori Agatsuma ,  Keisuke Fukuchi ,  Takehiro Hirai

IPC: A61K39/395 ,  C07K16/30

CPC classification number: C07K16/30 ,  C07K2317/732 ,  C12Q1/6886 ,  C12Q2600/136 ,  C12Q2600/158

Abstract: The present invention relates to a method of detecting cancer by use of an oncogene, a method of screening for an active compound useful to treat and/or prevent cancer, and a pharmaceutical composition for treatment and/or prevention of cancer. More specifically, the present invention provides a method of detecting cancer based on the expression of the human oculospanin gene as a marker and a pharmaceutical composition containing an antibody capable of specifically recognizing human oculospanin and having cytotoxic activity against cancer cells.

Abstract translation: 本发明涉及通过使用癌基因检测癌症的方法，筛选用于治疗和/或预防癌症的活性化合物的方法和用于治疗和/或预防癌症的药物组合物。 更具体地，本发明提供了一种基于人oculospanin基因作为标记物的表达和含有能够特异性识别人oculospanin并对癌细胞具有细胞毒性活性的抗体的药物组合物来检测癌症的方法。

公开(公告)号：US20080173902A1

公开(公告)日：2008-07-24

申请号：US12015608

申请日：2008-01-17

Applicant: Jiro MATSUDA ,  Masanori Nagase ,  Shu Takahashi

Inventor： Jiro MATSUDA ,  Masanori Nagase ,  Shu Takahashi

IPC: H01L31/0216 ,  H01L21/339

CPC classification number: H01L27/14812 ,  H01L29/66954 ,  H01L29/76833

Abstract: A solid state imaging apparatus comprises: a semiconductor substrate; a photoelectric converting portion on the semiconductor substrate; a light shielding film in a region excluding a light receiving surface of the photoelectric converting portion; and a P-type impurity layer between a lower surface of the light shielding film and the semiconductor substrate.

Abstract translation: 固态成像装置包括：半导体衬底; 半导体基板上的光电转换部; 在除光电转换部的受光面以外的区域中的遮光膜; 以及在遮光膜的下表面和半导体衬底之间的P型杂质层。

公开(公告)号：US20070166312A1

公开(公告)日：2007-07-19

申请号：US10548688

申请日：2004-03-09

Applicant: Kimihisa Ichikawa ,  Shu Takahashi ,  Toshinori Agatsuma ,  Keisuke Fukuchi ,  Takehiro Hirai

Inventor： Kimihisa Ichikawa ,  Shu Takahashi ,  Toshinori Agatsuma ,  Keisuke Fukuchi ,  Takehiro Hirai

IPC: A61K39/395 ,  C07K16/30 ,  C12Q1/68 ,  G01N33/574

CPC classification number: C07K16/30 ,  C07K2317/732 ,  C12Q1/6886 ,  C12Q2600/136 ,  C12Q2600/158

Abstract: The present invention relates to a method of detecting cancer by use of an oncogene, a method of screening for an active compound useful to treat and/or prevent cancer, and a pharmaceutical composition for treatment and/or prevention of cancer. More specifically, the present invention provides a method of detecting cancer based on the expression of the human oculospanin gene as a marker and a pharmaceutical composition containing an antibody capable of specifically recognizing human oculospanin and having cytotoxic activity against cancer cells.

Abstract translation: 本发明涉及通过使用癌基因检测癌症的方法，筛选用于治疗和/或预防癌症的活性化合物的方法和用于治疗和/或预防癌症的药物组合物。 更具体地，本发明提供了一种基于人oculospanin基因作为标记物的表达和含有能够特异性识别人oculospanin并对癌细胞具有细胞毒性活性的抗体的药物组合物来检测癌症的方法。

公开(公告)号：US20060127405A1

公开(公告)日：2006-06-15

申请号：US11223812

申请日：2005-09-09

Applicant: Kimihasa Ichikawa ,  Shu Takahashi ,  Toshinori Agatsuma ,  Keisuke Fukuchi ,  Takehiro Hirai

Inventor： Kimihasa Ichikawa ,  Shu Takahashi ,  Toshinori Agatsuma ,  Keisuke Fukuchi ,  Takehiro Hirai

IPC: A61K39/395 ,  C12Q1/68 ,  G01N33/574 ,  C07H21/04 ,  C12P21/06 ,  C12N5/06

CPC classification number: C07K16/30 ,  C07K2317/732 ,  C12Q1/6886 ,  C12Q2600/136 ,  C12Q2600/158

Abstract: The present invention relates to a method of detecting cancer by use of an oncogene, a method of screening for an active compound useful to treat and/or prevent cancer, and a pharmaceutical composition for treatment and/or prevention of cancer. More specifically, the present invention provides a method of detecting cancer based on the expression of the human oculospanin gene as a marker and a pharmaceutical composition containing an antibody capable of specifically recognizing human oculospanin and having cytotoxic activity against cancer cells.

Abstract translation: 本发明涉及通过使用癌基因检测癌症的方法，筛选用于治疗和/或预防癌症的活性化合物的方法和用于治疗和/或预防癌症的药物组合物。 更具体地，本发明提供了一种基于人oculospanin基因作为标记物的表达和含有能够特异性识别人oculospanin并对癌细胞具有细胞毒性活性的抗体的药物组合物来检测癌症的方法。

公开(公告)号：US20230334681A1

公开(公告)日：2023-10-19

申请号：US18133001

申请日：2023-04-11

Applicant: Hiroaki KUWABARA ,  Shu TAKAHASHI

Inventor： Hiroaki KUWABARA ,  Shu TAKAHASHI

IPC: G06T7/514 ,  G02B26/10 ,  G06T7/60 ,  G01B11/25

CPC classification number: G06T7/514 ,  G02B26/105 ,  G06T7/60 ,  G01B11/2518

Abstract: A shape-data acquisition apparatus obtains shape data of a work surface and includes an illuminator, a transmissive optical element, and an imager. The illuminator has a luminance distribution of a first cycle to irradiate the work surface. The transmissive optical element faces specular reflected light reflected by the work surface and has a transmittance distribution of a second cycle. The imager receives the specular reflected light to capture the work surface. The cyclic directions of the first cycle and the second cycle folded at a mirror image position on the work surface are parallel to each other. A relation of b=a×f2/f1 is satisfied when a is a distance between the illuminator and the work surface, b is a distance between the work surface and the transmissive optical element, f1 is the first cycle, and f2 is the second cycle.

公开(公告)号：US10048808B2

公开(公告)日：2018-08-14

申请号：US14940484

申请日：2015-11-13

Applicant: Koji Masuda ,  Yasuhiro Nihei ,  Takeshi Ueda ,  Masahiro Itoh ,  Shu Takahashi ,  Takeshi Ogawa ,  Hiroaki Tanaka ,  Shiori Ohta

Inventor： Koji Masuda ,  Yasuhiro Nihei ,  Takeshi Ueda ,  Masahiro Itoh ,  Shu Takahashi ,  Takeshi Ogawa ,  Hiroaki Tanaka ,  Shiori Ohta

IPC: G06F3/042 ,  G06F3/00 ,  G06F3/03 ,  H04N9/31 ,  H04N13/02 ,  H04N13/00

Abstract: An input operation detection device to detect input operation input to an image includes a first and second imaging parts and a processor to detect input operation based on data acquired by the first and second imaging parts. The image is divided into first and second images. The optical axes of imaging optical systems of the first and second imaging parts intersect with the image at points on the same side as installation position sides of the corresponding imaging parts with respect to the center of the corresponding images.

公开(公告)号：US20180136330A1

公开(公告)日：2018-05-17

申请号：US15808968

申请日：2017-11-10

Applicant: Yasuhiro Nihei ,  Toshishige Fujii ,  Takeshi Ogawa ,  Hiroaki Tanaka ,  Shu Takahashi ,  Yoichi Ichikawa ,  Masahiro Itoh

Inventor： Yasuhiro Nihei ,  Toshishige Fujii ,  Takeshi Ogawa ,  Hiroaki Tanaka ,  Shu Takahashi ,  Yoichi Ichikawa ,  Masahiro Itoh

IPC: G01S17/10 ,  G01S7/48 ,  G01S7/486

Abstract: An distance measurement apparatus includes a light source to emit irradiation light, circuitry to output, to the light source, a first current that changes in accordance of light-emission timing information defining at least turn-on timing of the light source, and a second current that does not change in accordance of the light-emission timing information, a sensor to detect reflection light reflected from an object irradiated with the irradiation light emitted from the light source. The circuitry calculates a distance to the object based on a detection amount of the reflection light detected by the sensor.

公开(公告)号：US20170199271A1

公开(公告)日：2017-07-13

申请号：US15403594

申请日：2017-01-11

Applicant: Yasuhiro NIHEI ,  Koji MASUDA ,  Takeshi OGAWA ,  Hiroaki TANAKA ,  Shu TAKAHASHI ,  Masahiro ITOH ,  Yoichi ICHIKAWA

Inventor： Yasuhiro NIHEI ,  Koji MASUDA ,  Takeshi OGAWA ,  Hiroaki TANAKA ,  Shu TAKAHASHI ,  Masahiro ITOH ,  Yoichi ICHIKAWA

IPC: G01S7/48 ,  B60Q11/00 ,  G01S17/93 ,  H05B37/02 ,  G01S17/10

CPC classification number: B60Q11/005 ,  G01S7/4815 ,  G01S7/484 ,  G01S7/497 ,  G01S17/10 ,  G01S17/89 ,  G01S17/936 ,  H05B33/0806 ,  H05B37/0227

Abstract: A distance measurement device includes a projection optical system, a light-receiving system to receive light projected from projection optical system and reflected by an object; and a correction system to correct a difference in timing of light emission between the plurality of light sources. The projection optical system includes a plurality of light sources and a plurality of drive circuits to drive the plurality of light sources.