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公开(公告)号:US09044332B2
公开(公告)日:2015-06-02
申请号:US13655269
申请日:2012-10-18
Applicant: Wright State University
Inventor: Tarun K. Goswami , Allison L. Van Horn , Alexander O. Sheets
CPC classification number: A61F2/4225 , A61F2/30734 , A61F2/30749 , A61F2002/30205 , A61F2002/30224 , A61F2002/30331 , A61F2002/30332 , A61F2002/30387 , A61F2002/30405 , A61F2002/30497 , A61F2002/305 , A61F2002/30579 , A61F2002/3085 , A61F2002/30878 , A61F2002/30884 , A61F2002/4235 , A61F2220/0008 , A61F2220/0025 , A61F2220/0033 , A61F2230/0067 , A61F2230/0069
Abstract: In various embodiments, provided are implantable devices for replacing all or a portion of a metatarsophalangeal joint, comprising (i) a metatarsal component comprising a substantially convex bearing surface; or (ii) a phalanx component comprising a substantially concave bearing surface; or (iii) both. In various embodiments, also provided are methods of treating hallux valgus by replacing all or a portion of a metatarsophalangeal joint with one or more of the provided implantable devices.
Abstract translation: 在各种实施例中,提供了用于替换跖趾指关节的全部或一部分的可植入装置,包括(i)包括基本凸起的支承表面的跖骨部件; 或(ii)包括基本上凹入的支承表面的指骨部件; 或(iii)两者。 在各种实施例中,还提供了通过用提供的可植入装置中的一个或多个替换跖趾关节的全部或一部分来治疗拇趾外翻的方法。
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22.
公开(公告)号:US20140195475A1
公开(公告)日:2014-07-10
申请号:US14143410
申请日:2013-12-30
Applicant: WRIGHT STATE UNIVERSITY , Aptima, Inc.
Inventor: Georgiy Levchuk , Jared Freeman , Wayne Shebilske
IPC: G06N7/00
Abstract: Embodiments of this invention comprise modeling a subject's state and the influence of training treatments, or actions, on that state to create a training policy. Both state and effects of actions are modeled as probabilistic using Partially Observable Markov Decision Process (POMDP) techniques. Utilizing this model and the resulting training policy with subjects creates an effective decision aid for instructors to improve learning relative to a traditional scenario selection strategy.
Abstract translation: 本发明的实施例包括对受试者的状态进行建模,以及训练治疗或动作对该状态的影响以创建训练策略。 动态的状态和效果都使用部分可观测马尔可夫决策过程(POMDP)技术进行建模。 利用这一模式和由此产生的培训策略为教师创造了有效的决策辅助,以提高相对于传统场景选择策略的学习。
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23.
公开(公告)号:US20240245703A1
公开(公告)日:2024-07-25
申请号:US18623530
申请日:2024-04-01
Applicant: Wright State University , TheUnited States of America as represented by the Department of Veterans Affairs
Inventor: Jeffrey B. TRAVERS
CPC classification number: A61K31/55 , A61K41/0061 , A61K45/06 , A61P17/16
Abstract: A skin protective composition includes at least one functional inhibitor of an acid sphingomyelinase (FIASM) in a dermatologically acceptable carrier. A method of ameliorating photosensitivity in a subject includes topically administering the skin protective composition to a subject, where the therapeutically effective amount is demonstrated to reduce or eliminate inflammation, microvesicle particle release, erythema, or a combination thereof. In another embodiment, a method inhibits the release of microvesicle particles from skin cells. In another embodiment, a method reduces side effects resulting from a topical photodynamic therapy treatment.
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公开(公告)号:US20240110843A1
公开(公告)日:2024-04-04
申请号:US18477192
申请日:2023-09-28
Applicant: WRIGHT STATE UNIVERSITY
Inventor: Zifeng YANG , Collin CHARVAT , Jack STAFFORD , Kyle MATHEWS , Logan KELLY
IPC: G01M9/04
CPC classification number: G01M9/04
Abstract: A dual airfoil testing system includes a platform including a frame defining a chamber that is configured to receive a horizontal flow of air for testing a first airfoil and a second airfoil contained in the chamber and a control system including a controller to control a first attack angle stepper motor, a second attack angle stepper motor, at least one gap stepper motor, and at least one stagger stepper motor. The controller is configured to automatically control and adjust the stepper motors to control and adjust the attack angle of the first airfoil, the attack angle of the second airfoil, the gap between the first airfoil and the second airfoil, and the stagger between the first airfoil and the second airfoil.
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公开(公告)号:US11774457B2
公开(公告)日:2023-10-03
申请号:US16506639
申请日:2019-07-09
Applicant: Wright State University
Inventor: James Edwin Olson , April Daubenspeck , David Cool , Bryan Ludwig
IPC: G01N33/68
CPC classification number: G01N33/6893 , G01N2800/2871 , G01N2800/52 , G01N2800/56 , G01N2800/60
Abstract: Protein biomarkers may be used to rapidly and accurately diagnose stroke. Biomarkers may be utilized in a rapid and inexpensive test that could be used at the bedside or ambulatory setting to definitively indicate the presence or absence of stroke and its severity. Such a test would quickly stratify patients in need of immediate stroke treatment from those who are not having a stroke. The test may aid emergency personnel in the decision for the most appropriate treatment plan and treatment location, thereby minimizing morbidity and mortality of stroke patients.
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公开(公告)号:US11666286B2
公开(公告)日:2023-06-06
申请号:US17305105
申请日:2021-06-30
Applicant: BAYLOR RESEARCH INSTITUTE , WRIGHT STATE UNIVERSITY
Inventor: Themistocles Dassopoulos , Nikolaos Bourbakis
IPC: G06T7/00 , G06T11/00 , G06V10/141 , G06V10/143 , G06V10/82 , A61B5/00 , G16H50/50 , G16H50/20 , G16H30/40 , G06F16/583 , G06N20/00 , G06N5/04 , G06F18/243 , G06V10/42 , G06V10/764 , A61B1/31 , G06V10/10
CPC classification number: A61B5/7267 , G06F16/583 , G06F18/24317 , G06N5/04 , G06N20/00 , G06T7/0014 , G06T11/001 , G06V10/141 , G06V10/143 , G06V10/431 , G06V10/764 , G06V10/82 , G16H30/40 , G16H50/20 , G16H50/50 , A61B1/31 , G06T2207/30004 , G06V10/16 , G06V2201/032
Abstract: Computational techniques are applied to video images of polyps to extract features and patterns from different perspectives of a polyp. The extracted features and patterns are synthesized using registration techniques to remove artifacts and noise, thereby generating improved images for the polyp. The generated images of each polyp can be used for training and testing purposes, where a machine learning system separates two types of polyps.
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公开(公告)号:US20200216473A1
公开(公告)日:2020-07-09
申请号:US16625023
申请日:2018-06-29
Applicant: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM , GEORGIA SOUTHERN UNIVERSITY , WRIGHT STATE UNIVERSITY
Inventor: Jonathan ARAMBULA , Kuppuswamy ARUMUGAM , Jonathan L. SESSLER , Christopher BIELAWSKI
Abstract: The present disclosure relates gold carbene naphthoquinone compounds and salts thereof. In some aspects, these compounds can be used to treat cancer including cancers which are resistant to one or more other chemotherapeutic agents such as cisplatin or platinum chemotherapeutic agents. Also provided herein are pharmaceutical compositions comprising the gold carbene naphthoquinone compounds.
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公开(公告)号:US10164609B2
公开(公告)日:2018-12-25
申请号:US15435847
申请日:2017-02-17
Applicant: Wright State University
Inventor: Jeffrey R. Smigelski
Abstract: A digital signal synthesizer for generating a frequency and/or phase modified digital signal output comprises an input buffer, a transform module, a processing module, and an output buffer. The input buffer receives a digital input that is represented in a frequency domain representation. The transform module stores a fractional order control system that models a desired frequency and/or phase response defined by an assembly of at least one filter component. Each filter component is defined by a Laplace function that is modified to include a non-integer control order having a variable fractional scaling exponent. The processing module multiplies or divides the digital input with the fractional order control system stored in the transform module. Moreover, the output buffer stores a synthesized output of the input, which is modified in the frequency domain, the phase domain, or both according to the desired frequency and/or phase response by the processing module.
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29.
公开(公告)号:US20180165249A1
公开(公告)日:2018-06-14
申请号:US15681516
申请日:2017-08-21
Applicant: Wright State University
Inventor: Jeffrey R. Smigelski
IPC: G06F17/14
CPC classification number: G06F17/141
Abstract: A method for processing a digital signal comprises identifying a desired frequency and/or phase response that is represented in a frequency domain representation. A fractional order control system that models the desired frequency and/or phase response is constructed by assembling a first filter component from a filter component library and a second filter component from the filter component library. At least one filter component of the filter component library is defined by a Laplace function that includes a non-integer control order having a variable fractional scaling exponent and a value for the non-integer, variable fractional scaling exponent of the second filter component is based on a value of the non-integer, variable fractional scaling exponent of the first filter component. An input in the digital frequency domain is received and processed based upon the fractional order control system to generate a digital output. The output is then conveyed to a user.
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公开(公告)号:US09647671B2
公开(公告)日:2017-05-09
申请号:US14987171
申请日:2016-01-04
Applicant: Wright State University
Inventor: Joseph Strzelecki , Saiyu Ren
CPC classification number: H03L7/091 , H03K3/356104 , H03K5/135 , H03L7/0891 , H03L7/18
Abstract: A phase frequency detector with two stages of operation; each stage containing two D flip-flops. Each D flip-flop is interconnected to eliminate detection dead zone while avoiding glitches and incorrect output conditions for fast phase locked loop convergence and wide-band applications.
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