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    Compositions, splice variants and methods relating to lung specific nucleic acids and proteins
    23.
    发明申请
    Compositions, splice variants and methods relating to lung specific nucleic acids and proteins 审中-公开
    与肺特异性核酸和蛋白质有关的组合物，剪接变体和方法

    公开(公告)号：US20050142572A1

    公开(公告)日：2005-06-30

    申请号：US10852707

    申请日：2004-05-24

    Applicant: Roberto Macina ,  Leah Turner ,  Yongming Sun

    Inventor： Roberto Macina ,  Leah Turner ,  Yongming Sun

    IPC: A61K48/00 ,  C07K14/47 ,  C12Q1/68 ,  C07H21/04

    CPC classification number: C12Q1/6886 ,  A61K48/00 ,  C07K14/47 ,  C12Q2600/112 ,  C12Q2600/136

    Abstract: The present invention relates to newly identified nucleic acid molecules and polypeptides present in normal and neoplastic lung cells, including fragments, variants and derivatives of the nucleic acids and polypeptides. The present invention also relates to antibodies to the polypeptides of the invention, as well as agonists and antagonists of the polypeptides of the invention. The invention also relates to compositions containing the nucleic acid molecules, polypeptides, antibodies, agonists and antagonists of the invention and methods for the use of these compositions. These uses include identifying, diagnosing, monitoring, staging, imaging and treating lung cancer and non-cancerous disease states in lung, identifying lung tissue, monitoring and identifying and/or designing agonists and antagonists of polypeptides of the invention. The uses also include gene therapy, production of transgenic animals and cells, and production of engineered lung tissue for treatment and research.

    Abstract translation: 本发明涉及存在于正常和肿瘤性肺细胞中的新鉴定的核酸分子和多肽，包括核酸和多肽的片段，变体和衍生物。 本发明还涉及本发明多肽的抗体，以及本发明多肽的激动剂和拮抗剂。 本发明还涉及含有本发明的核酸分子，多肽，抗体，激动剂和拮抗剂以及使用这些组合物的方法的组合物。 这些用途包括识别，诊断，监测，分期，成像和治疗肺中的肺癌和非癌性疾病状态，识别肺组织，监测和/或设计本发明多肽的激动剂和拮抗剂。 用途还包括基因治疗，转基因动物和细胞的生产以及用于治疗和研究的工程化肺组织的生产。

    Compositions and methods relating to prostate specific genes and proteins
    26.
    发明申请
    Compositions and methods relating to prostate specific genes and proteins 审中-公开
    与前列腺特异性基因和蛋白质有关的组成和方法

    公开(公告)号：US20050014710A1

    公开(公告)日：2005-01-20

    申请号：US10487556

    申请日：2002-08-29

    Applicant: Yongming Sun ,  Chenghua Liu ,  Sei-Yu Chen

    Inventor： Yongming Sun ,  Chenghua Liu ,  Sei-Yu Chen

    IPC: A61K38/00 ,  A61K48/00 ,  C07H21/04 ,  C07K14/47 ,  C07K14/705 ,  C12N15/12 ,  C12Q1/68 ,  C12Q1/6886 ,  G01N33/574

    CPC classification number: C07K14/4748 ,  A61K38/00 ,  A61K48/00 ,  C12Q1/6886 ,  C12Q2600/112 ,  C12Q2600/136 ,  G01N33/57434

    Abstract: The present invention relates to newly identified nucleic acid molecules and polypeptides present in normal and neoplastic prostate cells, including fragments, variants and derivatives of the nucleic acids and polypeptides. The present invention also relates to antibodies to the polypeptides of the invention, as well as agonists and antagonists of the polypeptides of the invention. The invention also relates to compositions containing the nucleic acid molecules, polypeptides, antibodies, agonists and antagonists of the invention and methods for the use of these compositions. These uses include identifying, diagnosing, monitoring, staging, imaging and treating prostate cancer and non-cancerous disease states in prostate, identifying prostate tissue, monitoring and identifying and/or designing agonists and antagonists of polypeptides of the invention. The uses also include gene therapy, production of transgenic animals and cells, and production of engineered prostate tissue for treatment and research.

    Abstract translation: 本发明涉及存在于正常和肿瘤前列腺细胞中的新鉴定的核酸分子和多肽，包括核酸和多肽的片段，变体和衍生物。 本发明还涉及本发明多肽的抗体，以及本发明多肽的激动剂和拮抗剂。 本发明还涉及含有本发明的核酸分子，多肽，抗体，激动剂和拮抗剂以及使用这些组合物的方法的组合物。 这些用途包括识别，诊断，监测，分期，成像和治疗前列腺中的前列腺癌和非癌性疾病状态，鉴定前列腺组织，监测和/或设计本发明多肽的激动剂和拮抗剂。 用途还包括基因治疗，转基因动物和细胞的生产，以及用于治疗和研究的工程前列腺组织的生产。

    Network-based method and apparatus for filtering junk messages
    28.
    发明授权
    Network-based method and apparatus for filtering junk messages 有权
    基于网络的垃圾邮件过滤方法和装置

    公开(公告)号：US08326776B2

    公开(公告)日：2012-12-04

    申请号：US12443371

    申请日：2007-08-27

    Applicant: Qijiang Dong ,  Yongming Sun

    Inventor： Qijiang Dong ,  Yongming Sun

    IPC: G06N5/00

    CPC classification number: G06Q10/107 ,  H04L51/12

    Abstract: The present invention discloses a network-based method and system for filtering a junk message. The method includes the following procedures: word-segmenting a target message to obtain characteristic elements within the target message; obtaining probabilities of the characteristic elements in the target message according to a predefined keyword library, the keyword library being updated periodically; and accumulating the probabilities of the characteristic elements in the target message, comparing accumulated probabilities with a predetermined threshold, and concluding the target message is a junk message if the result is greater than the predetermined threshold. Using a predefined keyword library for verification of a target message avoids time delay and system resource waste caused by massive and complicated computations during message verification in existing technologies, thus satisfying the requirement of real-time filtering of junk messages.

    Abstract translation: 本发明公开了一种用于过滤垃圾信息的基于网络的方法和系统。 该方法包括以下步骤：对目标消息进行字分割以获得目标消息内的特征元素; 根据预定义的关键字库获取目标消息中的特征元素的概率，定期更新关键字库; 并且累积目标消息中的特征元素的概率，将累积概率与预定阈值进行比较，并且如果结果大于预定阈值，则结束目标消息是垃圾消息。 使用预定义的关键字库来验证目标消息可以避免在现有技术的消息验证过程中大量复杂的计算造成的时间延迟和系统资源浪费，从而满足对垃圾邮件的实时过滤的要求。

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