公开(公告)号：US11879901B2

公开(公告)日：2024-01-23

申请号：US18166146

申请日：2023-02-08

Applicant: Access Medical Systems, LTD.

Inventor： Hong Tan ,  Ming Xia ,  Yushan Tan ,  Jun Chen ,  Erhua Cao ,  Genqian Li ,  Robert F. Zuk

IPC: B65G47/90 ,  G01N35/00 ,  B01L3/00 ,  G01N33/543 ,  G01N35/02 ,  G01N35/04

CPC classification number: G01N35/00 ,  B01L3/527 ,  G01N33/54353 ,  G01N33/54366 ,  B01L3/502 ,  B01L2200/16 ,  B01L2300/042 ,  B01L2300/045 ,  G01N35/026 ,  G01N2035/0436

Abstract: This invention relates to an apparatus for conducting immunoassay test. The apparatus includes a groove unit having a groove along a vertical direction configured to hold a rod-shaped portion of a probe along the vertical direction, and a push pin configured to move along a horizontal direction, the push pin being capable of residing at a first position and a second position. A tip of the push pin is capable of pressing the rod-shaped portion of the probe against the groove when the push pin resides at the first position. The distance between the tip of the push pin and the groove is larger than a diameter of the rod-shaped portion of the probe when the push pin resides at the second position.

公开(公告)号：US20210172970A1

公开(公告)日：2021-06-10

申请号：US17181868

申请日：2021-02-22

Applicant: Access Medical Systems, LTD.

Inventor： Hong Tan ,  Yongli Ren ,  Ming Xia ,  Genqian Li

IPC: G01N35/00 ,  B01L3/00 ,  B01L9/00 ,  G01N33/53 ,  G01N33/536

Abstract: This invention relates to a cartridge assembly tray for conducting automated biochemical tests, such as immunoassay tests. The tray comprises a base member, a hinged frame and a locking mechanism. The base member includes a plurality of slots within the base member. Each of the plurality of slots is to receive a test cartridge. The hinged frame is coupled to the base member. The hinged frame is capable to rotate to an opened position or a closed position. The hinged frame includes a horizontal push bar configured to apply a downward force to test cartridges received in the plurality of slots when the hinged frame is in the closed position. The locking mechanism is to lock the hinged frame in the closed position when the hinged frame rotates to the closed position.

公开(公告)号：US09719936B2

公开(公告)日：2017-08-01

申请号：US14604584

申请日：2015-01-23

Applicant: ACCESS MEDICAL SYSTEMS, LTD.

Inventor： Hong Tan ,  Yushan Tan ,  Erhua Cao ,  Ming Xia ,  Robert F. Zuk

IPC: G02B6/30 ,  G02B6/26 ,  G01N21/45 ,  G01N21/85 ,  G01N21/77 ,  G01J3/45 ,  G01N21/64

CPC classification number: G01N21/7703 ,  G01J3/45 ,  G01N21/45 ,  G01N21/648 ,  G01N21/8507 ,  G01N2021/7779 ,  G01N2201/062 ,  G01N2201/08 ,  G02B6/262 ,  G02B6/30

Abstract: The present invention is directed to an assembly for use in detecting an analyte in a sample based on thin-film spectral interference. The assembly comprises a waveguide, a monolithic substrate optically coupled to the waveguide, and a thin-film layer directly bonded to the sensing side of the monolithic substrate. The refractive index of the monolithic substrate is higher than the refractive index of the transparent material of the thin-film layer. A spectral interference between the light reflected into the waveguide from a first reflecting surface and a second reflecting surface varies as analyte molecules in a sample bind to the analyte binding molecules coated on the thin-film layer.

公开(公告)号：US20150204795A1

公开(公告)日：2015-07-23

申请号：US14604584

申请日：2015-01-23

Applicant: ACCESS MEDICAL SYSTEMS, LTD.

Inventor： Hong Tan ,  Yushan Tan ,  Erhua Cao ,  Ming Xia ,  Robert F. Zuk

IPC: G01N21/77 ,  G02B6/30 ,  G01J3/45 ,  G02B6/26

CPC classification number: G01N21/7703 ,  G01J3/45 ,  G01N21/45 ,  G01N21/648 ,  G01N21/8507 ,  G01N2021/7779 ,  G01N2201/062 ,  G01N2201/08 ,  G02B6/262 ,  G02B6/30

Abstract: The present invention is directed to an assembly for use in detecting an analyte in a sample based on thin-film spectral interference. The assembly comprises a waveguide, a monolithic substrate optically coupled to the waveguide, and a thin-film layer directly bonded to the sensing side of the monolithic substrate. The refractive index of the monolithic substrate is higher than the refractive index of the transparent material of the thin-film layer. A spectral interference between the light reflected into the waveguide from a first reflecting surface and a second reflecting surface varies as analyte molecules in a sample bind to the analyte binding molecules coated on the thin-film layer.

Abstract translation: 本发明涉及一种用于基于薄膜光谱干涉检测样品中的分析物的组件。 组件包括波导，光耦合到波导的单片基板，以及直接结合到整体式基板的感测侧的薄膜层。 单片基板的折射率高于薄膜层的透明材料的折射率。 当样品中的分析物分子结合到涂覆在薄膜层上的分析物结合分子时，从第一反射表面和第二反射表面反射到波导中的光之间的光谱干涉变化。