公开(公告)号：US08472027B2

公开(公告)日：2013-06-25

申请号：US13178695

申请日：2011-07-08

Applicant: Adrian Podoleanu

Inventor： Adrian Podoleanu

IPC: G01B9/02

CPC classification number: A61B3/102 ,  A61B5/0064 ,  A61B5/0066 ,  A61B5/0073 ,  A61B5/441 ,  A61B5/7203 ,  A61B5/7257 ,  G01B9/02044 ,  G01B9/02069 ,  G01B9/02091 ,  G01N21/4795

Abstract: A spectral interferometry apparatus and method is provided to supply unambiguous profiles (A-scans free of mirror terms) of the reflectivity versus optical path difference and make difference between the positive and negative optical path difference or provide output in a selected interval of optical path differences. The apparatus comprises object optics that transfer a beam from an optical source to a target object (55) to produce an object beam and reference optics that produce a reference beam. Displacing means (57) are provided to produce a gap (g) between the object beam (41′) and the reference beam (42′). Optical spectrum dispersing means (7) such as a grating or a prism receive the two relatively displaced beams, and disperse their spectral content onto a reading element such as a CCD. The combination of the displacing means and the optical spectrum dispersing means creates an intrinsic optical delay between the wavetrains of the object beam and the reference beam which can be used with the optical path difference in the interferometer to generate a channelled spectrum for the optical path difference in the interferometer on the reading element.

Abstract translation: 提供了一种光谱干涉测量装置和方法来提供反射率相对于光程差的明确分布（无镜像的A扫描），并使得在正和负光程差之间产生差异，或者在所选择的光程差间隔中提供输出 。 该装置包括将光束从光源传输到目标物体（55）以产生物体光束和产生参考光束的参考光学器件的物体光学器件。 设置位移装置（57）以在物体光束（41'）和参考光束（42'）之间产生间隙（g）。 诸如光栅或棱镜的光谱分散装置（7）接收两个相对移动的光束，并将其光谱含量分散到诸如CCD的读取元件上。 位移装置和光谱分散装置的组合在物体光束的波长与参考光束之间产生固有的光学延迟，该参考光束可与干涉仪中的光程差用于产生用于光程差的通道光谱 在干涉仪上读取元件。

公开(公告)号：US20120013909A1

公开(公告)日：2012-01-19

申请号：US12958791

申请日：2010-12-02

Applicant: Adrian Podoleanu ,  Michael Leitner

Inventor： Adrian Podoleanu ,  Michael Leitner

IPC: G01J3/45 ,  A61B3/10

CPC classification number: A61B3/1225 ,  A61B3/102 ,  A61B3/103 ,  G01B9/02004 ,  G01B9/02027 ,  G01B9/02044 ,  G01B9/02065 ,  G01B9/02089 ,  G01B9/0209

Abstract: A spectral interferometry apparatus and method are disclosed, that can be used to monitor or measure an unknown length by following a characteristic of an indicating signal. The measurement is performed by adjusting an optical path difference (OPD) in an interferometer part of an interferometer configuration until sound or light or both are obtained with the desired strength and pitch. Embodiments are presented where the unknown length is the eye length. Spectral interrogation of the interferometer optical output is achieved by reading the signal of an analogue photodetector array in a spectrometer or by tuning a swept source and processing the signal of a photodetector. Sound of different pitches are produced either directly in this process, or by using a nonlinear amplifier, or a mixer. For enhanced signal, the array may be driven by a nonlinear clock or the swept source may be driven by a distorted driving signal.

Abstract translation: 公开了一种光谱干涉测量装置和方法，其可以用于通过遵循指示信号的特性来监视或测量未知长度。 通过调整干涉仪配置的干涉仪部分中的光程差（OPD）来进行测量，直到以期望的强度和间距获得声音或光或者两者。 呈现其中未知长度是眼睛长度的实施例。 通过读取光谱仪中的模拟光电检测器阵列的信号或通过调谐扫频源并处理光电检测器的信号来实现干涉仪光输出的光谱询问。 在该过程中直接产生不同音调的声音，或者通过使用非线性放大器或混音器产生声音。 对于增强的信号，阵列可以由非线性时钟驱动，或者扫描的源可以由失真的驱动信号驱动。

公开(公告)号：US20110134436A1

公开(公告)日：2011-06-09

申请号：US12764510

申请日：2010-04-21

Applicant: Adrian Podoleanu ,  Simon Tuohy

Inventor： Adrian Podoleanu ,  Simon Tuohy

IPC: G01B11/02

CPC classification number: G01B9/02004 ,  A61B3/1015 ,  A61B3/102 ,  A61B3/156 ,  G01B9/02002 ,  G01B9/0201 ,  G01B9/02027 ,  G01B9/02038 ,  G01B9/02063 ,  G01B9/02068 ,  G01B9/0209 ,  G01B9/02091 ,  G01B2290/45 ,  G01B2290/70

Abstract: Methods and devices are disclosed for acquiring depth resolved aberration information using principles of low coherence interferometry and perform coherence gated wavefront sensing (CG-WFS). The wavefront aberrations is collected using spectral domain low coherence interferometry (SD-LCI) or time domain low coherence interferometry (TD-LCI) principles. When using SD-LCI, chromatic aberrations can also be evaluated. Methods and devices are disclosed in using a wavefront corrector to compensate for the aberration information provided by CG-WFS, in a combined imaging system, that can use one or more channels from the class of (i) optical coherence tomography (OCT), (ii) scanning laser ophthalmoscopy, (iii) microscopy, such as confocal or phase microscopy, (iv) multiphoton microscopy, such as harmonic generation and multiphoton absorption. In particular, a swept source (SS) is used that drives both an OCT channel and a coherence gated wavefront sensor, where: a) both channels operate according to SS-OCT principles; b) OCT channel integrates over at least one tuning scan of the swept source to provide a TD-OCT image of the object; c) CG-WFS integrates over at least one tuning scan of the swept source to provide an en-face TD-OCT mapping of the wavefront. For some implementations, simultaneous and dynamic aberration measurements/correction with the imaging process is achieved. The methods and devices for depth resolved aberrations disclosed, will find applications in wavefront sensing and adaptive optics imaging systems that are more tolerant to stray reflections from optical interfaces, such as reflections from the microscope objectives and cover slip in microscopy and when imaging the eye, the reflection from the cornea.

Abstract translation: 公开了使用低相干干涉测量原理获取深度分辨像差信息并执行相干门控波前检测（CG-WFS）的方法和装置。 使用频域低相干干涉测量（SD-LCI）或时域低相干干涉测量（TD-LCI）原理收集波前像差。 当使用SD-LCI时，也可以评估色差。 在使用波前校正器来补偿在组合成像系统中由CG-WFS提供的像差信息的方法和装置被公开，该组合成像系统可以使用来自（i）光学相干断层扫描（OCT）的一个或多个通道， ii）扫描激光眼底镜检查，（iii）显微镜，如共焦或相位显微镜，（iv）多光子显微镜，如谐波产生和多光子吸收。 特别地，使用驱动OCT通道和相干门控波前传感器的扫频源（SS），其中：a）两个通道根据SS-OCT原理操作; b）OCT信道在扫描源的至少一次调谐扫描上进行积分以提供对象的TD-OCT图像; c）CG-WFS集成了扫描源的至少一个调谐扫描，以提供波前的面向TD-OCT映射。 对于一些实施方案，实现了通过成像过程的同步和动态像差测量/校正。 所公开的用于深度分辨像差的方法和装置将会在波前感测和自适应光学成像系统中应用，这些系统对光学界面的杂散反射更为宽容，例如来自显微镜物镜的反射和显微镜下的盖滑动以及当成像眼睛时， 角膜的反射。