公开(公告)号：US20170224534A1

公开(公告)日：2017-08-10

申请号：US15472551

申请日：2017-03-29

Applicant: Clearside Biomedical, Inc.

Inventor： Rafael Victor ANDINO ,  Vladimir ZARNITSYN ,  Jesse YOO ,  Christopher John BROOKS ,  Trent John KAHUTE ,  Justin William ARSENAULT ,  David Jackson TRETTIN ,  Andrew Kent BAUER ,  Stephanie Elaine LEWIS

IPC: A61F9/00 ,  A61M5/20 ,  A61M37/00 ,  A61M5/34 ,  A61M5/46 ,  A61M5/48 ,  A61J1/20 ,  A61M5/32

CPC classification number: A61F9/0017 ,  A61F2250/0007 ,  A61F2250/0069 ,  A61J1/201 ,  A61J1/2055 ,  A61J1/2096 ,  A61M5/2033 ,  A61M5/2053 ,  A61M5/31 ,  A61M5/3293 ,  A61M5/34 ,  A61M5/344 ,  A61M5/346 ,  A61M5/347 ,  A61M5/348 ,  A61M5/349 ,  A61M5/46 ,  A61M5/482 ,  A61M37/0015 ,  A61M2005/31508 ,  A61M2037/0023 ,  A61M2037/0061 ,  A61M2210/0612

Abstract: An apparatus includes a housing coupled to a medicament container, which is coupled to a needle. An injection assembly is disposed within the housing and includes an energy storage member and an actuation rod. A distal end portion of the actuation rod is disposed within the medicament container. The energy storage member can produce a force on a proximal end portion of the actuation rod sufficient to move the distal end portion of the actuation rod within the medicament container. This can convey at least a portion of a substance from the medicament container via the needle when a distal tip of the needle is disposed within a first region of a target location. The force is insufficient to move the distal end portion of the actuation rod within the medicament container when the distal tip of the needle is disposed within a second region of the target location.

公开(公告)号：US20170224435A1

公开(公告)日：2017-08-10

申请号：US15427823

申请日：2017-02-08

Applicant: Clearside Biomedical, Inc.

Inventor： Thomas Edward GODFREY ,  Rafael Victor ANDINO ,  Shelley Eckert HANCOCK ,  Keleigh Jo STRUDTHOFF

IPC: A61B50/33 ,  B65D25/02 ,  A61F9/00 ,  B65D77/04 ,  B65D75/36 ,  B65D25/20 ,  A61M5/00

CPC classification number: A61B50/33 ,  A61B50/20 ,  A61B50/30 ,  A61B2050/0065 ,  A61B2050/3008 ,  A61B2050/3015 ,  A61F9/0008 ,  A61F9/0017 ,  A61J1/00 ,  A61M5/002 ,  A61M2209/06 ,  B65D25/02 ,  B65D25/205 ,  B65D75/36 ,  B65D75/367 ,  B65D77/0433

Abstract: An apparatus includes a first tray member, a second tray member, and a lid. The first tray member has a first portion and a second portion. The first portion defines a first volume, and the second portion defines a second volume configured to receive a medicament container. The second tray member defines a third volume having a sidewall including a retention portion configured to retain an ocular injector within the third volume. The second tray member is coupled within first volume such that the sidewall of the second tray member and a sidewall of the first tray member enclose the ocular injector. The lid is coupled to the first tray member about the first volume, and is constructed from a material formulated to maintain sterility of the first volume.

公开(公告)号：US20160106584A1

公开(公告)日：2016-04-21

申请号：US14894161

申请日：2014-05-30

Applicant: CLEARSIDE BIOMEDICAL, INC.

Inventor： Rafael Victor ANDINO ,  Samirkumar R. PATEL ,  Vladimir ZARNITSYN ,  Christopher John BROOKS

IPC: A61F9/00 ,  A61M5/19

CPC classification number: A61F9/0017 ,  A61J1/2093 ,  A61M5/19 ,  A61M5/284 ,  A61M2005/31598

Abstract: A cartridge, including a first member that defines an inner volume and a second member disposed therein, is disposed in a housing. A first reservoir is disposed in the inner volume in a position distal to the second member. The first member is partially disposed in a second reservoir, defined by the housing. The second member is configured to be moved from a first position, in which the first reservoir contains a drug and the second reservoir is fluidically isolated from the inner volume, toward a second position, in which the first reservoir and the second reservoir are in fluid communication with the inner volume, such that the second reservoir receives a volume of the drug from the first reservoir. The first member and the second member are collectively moved relative to the second reservoir to expel the volume of the drug from the second reservoir.

Abstract translation: 包括限定内部容积的第一构件和设置在其中的第二构件的盒设置在壳体中。 第一储存器设置在内容积中远离第二构件的位置。 第一构件部分地设置在由壳体限定的第二储存器中。 第二构件被构造成从第一位置移动，其中第一储存器包含药物，并且第二储存器与内容积流体隔离，朝向第二位置移动，第二储存器和第二储存器处于流体 与内部容积连通，使得第二储存器从第一储存器接收一定体积的药物。 第一构件和第二构件相对于第二储存器共同移动以从第二储存器排出药物的体积。