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公开(公告)号:US12161743B2
公开(公告)日:2024-12-10
申请号:US17695100
申请日:2022-03-15
Applicant: Colgate-Palmolive Company
Inventor: Zhigang Hao , Chi-Yuan Cheng , Long Pan , Ravi Subramanyam
Abstract: The present disclosure provides a chlorhexidine-cyclamate complex having a formula [C22H32Cl2N10][C6H12NO3S]2 having antibacterial and antiplaque properties, together with oral care compositions comprising the complex, and methods of making and using these complexes and compositions.
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公开(公告)号:US20240325440A1
公开(公告)日:2024-10-03
申请号:US18738288
申请日:2024-06-10
Applicant: Colgate-Palmolive Company
Inventor: Baohua Qiao , Long Pan , Gregory Szewczyk , Ravi Subramanyam
IPC: A61K33/42 , A61K6/20 , A61K6/74 , A61K8/24 , A61K8/27 , A61K9/00 , A61K33/30 , A61Q11/00 , A61Q15/00 , C01B25/37
CPC classification number: A61K33/42 , A61K6/20 , A61K6/74 , A61K8/24 , A61K8/27 , A61K9/0063 , A61K33/30 , A61Q11/00 , A61Q15/00 , C01B25/37 , A61K2800/262 , A61K2800/58
Abstract: A soluble zinc polyphosphate complex made by combining ingredients which include an inorganic zinc salt and a plurality of long chain polyphosphates having 6 or more phosphate polymer units, the relative amount of inorganic zinc salt and long chain polyphosphates providing a phosphorus to zinc mole ratio of at least 6:1. Further provided is a method of making this soluble zinc polyphosphate.
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公开(公告)号:US12005076B2
公开(公告)日:2024-06-11
申请号:US15538330
申请日:2014-12-26
Applicant: Colgate-Palmolive Company
Inventor: Baohua Qiao , Long Pan , Gregory Szewczyk , Ravi Subramanyam
IPC: A61K33/42 , A61K6/20 , A61K6/74 , A61K8/24 , A61K8/27 , A61K9/00 , A61K33/30 , A61Q11/00 , A61Q15/00 , C01B25/37
CPC classification number: A61K33/42 , A61K6/20 , A61K6/74 , A61K8/24 , A61K8/27 , A61K9/0063 , A61K33/30 , A61Q11/00 , A61Q15/00 , C01B25/37 , A61K2800/262 , A61K2800/58 , A61K33/42 , A61K2300/00 , A61K33/30 , A61K2300/00
Abstract: A soluble zinc polyphosphate complex made by combining ingredients which include an inorganic zinc salt and a plurality of long chain polyphosphates having 6 or more phosphate polymer units, the relative amount of inorganic zinc salt and long chain polyphosphates providing a phosphorus to zinc mole ratio of at least 6:1. Further provided is a method of making this soluble zinc polyphosphate.
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公开(公告)号:US11344486B2
公开(公告)日:2022-05-31
申请号:US16425122
申请日:2019-05-29
Applicant: Colgate-Palmolive Company
Inventor: Baohua Qiao , Long Pan , Gregory Szewczyk , Ravi Subramanyam , Shiri Nawrocki , Viktor Dubovoy
Abstract: A soluble zinc polyphosphate complex made by combining ingredients which include an organic zinc salt and a plurality of long chain polyphosphates having 6 or more phosphate polymer units, the organic zinc salt and long chain polyphosphates being mixed in amounts that provide a phosphorus to zinc mole ratio of 15:1 to about 55:1. Further provided is a method of making this soluble zinc polyphosphate.
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公开(公告)号:US11033594B2
公开(公告)日:2021-06-15
申请号:US14648715
申请日:2013-03-07
Applicant: Colgate-Palmolive Company
Inventor: Shashank Potnis , Ravi Subramanyam , Rajitha Nair
IPC: A61K36/61 , A61K9/00 , A61K31/125 , A61K47/18 , A61K47/32 , A61K31/085 , A61K9/06 , A61K31/045 , A61K36/48 , A61K36/185
Abstract: Disclosed herein are orally acceptable topical analgesic gels comprising a mixture of analgesic oils comprising (a) clove oil and/or eugenol, (b) a cooling agent, and (c) camphor, in an orally acceptable gel base, the gel base comprising an anionic polymer and a basic amino acid, and the analgesic gel providing controlled release of the mixture of analgesic oils following application to a tooth together with a methods of making and using the same.
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公开(公告)号:US10532016B2
公开(公告)日:2020-01-14
申请号:US16213871
申请日:2018-12-07
Applicant: Colgate-Palmolive Company
Inventor: Zhigang Hao , Dennis Zhang , Donghui Wu , Ravi Subramanyam , Chi-Yuan Cheng , Long Pan , Stanislav Jaracz
Abstract: Disclosed herein are zinc-amino acid-tripolyphosphate complexes, oral care and personal care compositions comprising zinc-amino acid-tripolyphosphate complexes, and methods of making and using the same.
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公开(公告)号:US10251823B2
公开(公告)日:2019-04-09
申请号:US15525381
申请日:2015-11-13
Applicant: Colgate-Palmolive Company
Inventor: Ravi Subramanyam , Suzanne Jogun , Mahmoud Hassan , Navin Lewis , Xiao Yi Huang , Shao Peng Xu
IPC: A61K8/27 , A61K8/25 , A61K8/365 , A61Q11/00 , A61K8/02 , A61K8/04 , A61K8/19 , A61K8/21 , A61K8/37
Abstract: The present invention provides an oral care composition comprising: (a) a first composition comprising a silica abrasive and a first zinc compound selected from zinc citrate, zinc chloride, zinc acetate, zinc lactate, zinc salicylate, zinc sulfate, and zinc nitrate; and (b) a second composition comprising a calcium carbonate abrasive; wherein the first composition and/or the second composition further comprises a second zinc compound selected from zinc oxide, zinc carbonate and zinc tartrate; and wherein the oral care composition optionally further comprises from 0.1 to 1.75 weight % of a tartar control agent, based on the total weight of the oral care composition.
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公开(公告)号:US09913784B2
公开(公告)日:2018-03-13
申请号:US15385054
申请日:2016-12-20
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor: Gregory Szewczyk , Lisa Manus , Lyndsay Schaeffer-Korbylo , Andrei Potanin , Ravi Subramanyam
CPC classification number: A61K8/27 , A61K8/21 , A61K8/24 , A61K8/44 , A61K8/8176 , A61K8/8182 , A61K2800/58 , A61Q11/00 , A61Q11/02
Abstract: Disclosed herein are oral care compositions comprising a zinc amino acid halide complex, and linear polyvinylpyrrolidone and/or sodium tripolyphosphate, which compositions have improved rheological stability. Methods of making and using the compositions are also provided.
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公开(公告)号:US09676690B2
公开(公告)日:2017-06-13
申请号:US14762998
申请日:2013-01-23
Applicant: Colgate-Palmolive Company
Inventor: Basi V. Subba Reddy , Ravi Subramanyam , Shashank Potnis , Jhillu Singh Yadav
CPC classification number: C07C37/055 , A61K8/33 , A61Q11/00 , C07C37/003 , C07C41/06 , C07C41/16 , C07C43/215 , C07C39/21 , C07C39/15
Abstract: Described herein are high yield methods for making magnolol derivatives, together with novel intermediates and uses thereof.
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公开(公告)号:US20150361017A1
公开(公告)日:2015-12-17
申请号:US14762998
申请日:2013-01-23
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor: Basi V. Subba Reddy , Ravi Subramanyam , Shashank Potnis , Jhillu Singh Yadav
IPC: C07C37/055 , C07C37/00 , C07C41/06
CPC classification number: C07C37/055 , A61K8/33 , A61Q11/00 , C07C37/003 , C07C41/06 , C07C41/16 , C07C43/215 , C07C39/21 , C07C39/15
Abstract: Described herein are high yield methods for making magnolol derivatives, together with novel intermediates and uses thereof.
Abstract translation: 本文描述了制备厚朴酚衍生物的高产率方法,以及新的中间体及其用途。
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