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公开(公告)号：US11826448B2
公开(公告)日：2023-11-28
申请号：US17249523
申请日：2021-03-04
Applicant: Colgate-Palmolive Company
Inventor： Zhigang Hao , Chi-Yuan Cheng , Tatiana Brinzari , Long Pan , Ravi Subramanyam
Abstract: The disclosure provides a zinc-arginine complex, methods of making the same, and methods of using the same in oral care compositions.
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公开(公告)号：US11117906B2
公开(公告)日：2021-09-14
申请号：US16714903
申请日：2019-12-16
Applicant: Colgate-Palmolive Company
Inventor： Zhigang Hao , Chi-Yuan Cheng , Tatiana Brinzari , Long Pan , Ravi Subramanyam , Lauren Evans , Sergio Leite
IPC: C07F3/06 , A61K8/27 , A61K8/44 , C07C229/26
Abstract: Disclosed herein are improved methods for the synthesis of zinc-amino acid-halide complexes via reaction of zinc oxide and amino acid hydrochloride in a solvent comprising a polyol, as well as oral care compositions comprising said complexes made according to said method.
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公开(公告)号：US10857083B2
公开(公告)日：2020-12-08
申请号：US16216533
申请日：2018-12-11
Applicant: Colgate-Palmolive Company
Inventor： Long Pan , Donghui Wu , Ravi Subramanyam , Hongwei Shen , Chi-Yuan Cheng , Tatiana Brinzari
IPC: A61K8/44 , A61Q11/00 , C07C271/06 , C07C279/14 , C07C269/04 , A61K31/4172 , A61K8/21 , A61K33/16 , A61K31/198 , A61K8/49 , A61K8/19
Abstract: Disclosed herein are amino acid carbamate complexes, methods of synthesis thereof, oral care compositions comprising the same, and methods of making and using thereof.
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公开(公告)号：US20240199538A1
公开(公告)日：2024-06-20
申请号：US18531066
申请日：2023-12-06
Applicant: Colgate-Palmolive Company
Inventor： Viktor DUBOVOY , Dailin Chen , Zhigang Hao , Xing He , Long Pan , Chi-Yuan Cheng , Yu Wang , Jake Salerno , Tatiana Brinzari
IPC: C07C279/18 , A01N47/44 , A01P1/00 , A61K8/43 , A61Q11/00 , A61Q17/00 , C07C305/04
CPC classification number: C07C279/18 , A01N47/44 , A01P1/00 , A61K8/43 , A61Q11/00 , A61Q17/005 , C07C305/04 , C07B2200/13
Abstract: This application relates to a novel chlorhexidine lauryl sulfate salt, which provides enhanced chlorhexidine stability and enhanced anti-bacterial activity, and to formulations and methods utilizing the novel salt.
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公开(公告)号：US11091502B2
公开(公告)日：2021-08-17
申请号：US16714884
申请日：2019-12-16
Applicant: Colgate-Palmolive Company
Inventor： Zhigang Hao , Chi-Yuan Cheng , Tatiana Brinzari , Long Pan , Ravi Subramanyam
IPC: C07F3/06 , A61K8/27 , A61K8/44 , C07C229/26
Abstract: Disclosed herein are improved methods for the synthesis of zinc-amino acid-halide complexes via reaction of zinc halide and amino acid free base in a solvent comprising a polyol, as well as oral care compositions comprising said complexes made according to said method.
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Patent Agency Ranking
公开(公告)号：US10952943B2
公开(公告)日：2021-03-23
申请号：US16714972
申请日：2019-12-16
Applicant: Colgate-Palmolive Company
Inventor： Zhigang Hao , Chi-Yuan Cheng , Tatiana Brinzari , Long Pan , Ravi Subramanyam
Abstract: The disclosure provides a zinc-arginine complex, methods of making the same, and methods of using the same in oral care compositions.
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公开(公告)号：US20190231667A1
公开(公告)日：2019-08-01
申请号：US16266661
申请日：2019-02-04
Applicant: Colgate-Palmolive Company
Inventor： Jane Ong , James Masters , Tatiana Brinzari , Chi-Yuan Cheng , Donghui Wu , Long Pan
Abstract: Disclosed herein are oral care compositions comprising naringin:Zinc complexes having a 2:1 naringin to zinc molar ratio. Methods of making and using the compositions are also provided.
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公开(公告)号：US12161743B2
公开(公告)日：2024-12-10
申请号：US17695100
申请日：2022-03-15
Applicant: Colgate-Palmolive Company
Inventor： Zhigang Hao , Chi-Yuan Cheng , Long Pan , Ravi Subramanyam
Abstract: The present disclosure provides a chlorhexidine-cyclamate complex having a formula [C22H32Cl2N10][C6H12NO3S]2 having antibacterial and antiplaque properties, together with oral care compositions comprising the complex, and methods of making and using these complexes and compositions.
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公开(公告)号：US11892435B2
公开(公告)日：2024-02-06
申请号：US16703985
申请日：2019-12-05
Applicant: Colgate-Palmolive Company
Inventor： Chi-Yuan Cheng , Zhigang Hao , Long Pan , Zolijargal Balsandorj
IPC: G01N33/15 , G01N24/08 , G01N31/22 , G01R33/465
CPC classification number: G01N31/221 , G01N24/08 , G01R33/465
Abstract: Methods for measuring pH of gel, paste, colloid, and aqueous solutions, such as a consumer product, a food product, a pet food product, a beverage product, a pharmaceutical product, and/or a medical product, are provided. The method may include preparing a calibration curve of a chemical species including or having an acid dissociation constant. Preparing the calibration curve may include plotting a chemical shift of the chemical species relative to pH. The method may also include determining a chemical shift of a gel, paste, and colloid, aqueous solutions, such as a consumer product, a food product, a pet food product, a beverage product, a pharmaceutical product, and/or a medical product, including the chemical species. The method may further include determining the pH of the gel, paste, colloid, and aqueous solutions, such as a consumer product, a food product, a pet food product, a beverage product, a pharmaceutical product, and/or a medical product, with the chemical shift of the product and the calibration curve.
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公开(公告)号：US11116708B2
公开(公告)日：2021-09-14
申请号：US16758434
申请日：2017-12-19
Applicant: Colgate-Palmolive Company
Inventor： Shujiang Cheng , Zeenat Nabi , Laurence Du-Thumm , Qiang Wu , Jane Ong , Halyna Siomyk , Harsh Mahendra Trivedi , James Masters , Chi-Yuan Cheng , Donghui Wu
Abstract: Personal care compositions including a naringin:zinc complex and methods for preparing and using the same are provided. The personal care compositions may include a carrier and a naringin:zinc complex having a 2:1 naringin to zinc molar ratio.
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