公开(公告)号：US09827177B2

公开(公告)日：2017-11-28

申请号：US14649946

申请日：2012-12-19

Applicant: Colgate-Palmolive Company

Inventor： Shaotang Yuan ,  Long Pan

IPC: A61K8/44 ,  A61K8/27 ,  A61K8/64 ,  A61Q15/00

CPC classification number: A61K8/27 ,  A61K8/44 ,  A61K8/64 ,  A61K2800/58 ,  A61K2800/874 ,  A61Q15/00

Abstract: The invention provides antiperspirant formulations comprising a protein and an antiperspirant salt in combination with a cosmetically acceptable carrier, together with methods of making and using these complexes and compositions.

公开(公告)号：US09757316B2

公开(公告)日：2017-09-12

申请号：US14653314

申请日：2012-12-19

Applicant: Colgate-Palmolive Company

Inventor： Long Pan ,  Jairajh Mattai ,  Shaotang Yuan ,  James G. Masters

IPC: A61K8/44 ,  A61K8/27 ,  A61Q11/00 ,  A61Q15/00 ,  A61Q17/00 ,  A61Q5/02 ,  A61Q5/12 ,  A61Q19/10 ,  C07F3/06

CPC classification number: A61K8/27 ,  A61K8/44 ,  A61K2800/58 ,  A61K2800/591 ,  A61Q5/02 ,  A61Q5/12 ,  A61Q11/00 ,  A61Q15/00 ,  A61Q17/005 ,  A61Q19/10 ,  C07B2200/13 ,  C07F3/06

Abstract: The invention provides a zinc-lysine complex having the formula [Zn(C6H14N2O2)2Cl]+Cl− having antibacterial and antiperspirant properties, together with personal care compositions comprising the complex, and methods of making and using these complexes and compositions. The application discloses a general reaction for formation of such complexes by mixing a Zn source with Lysine in 1:2 ratio: ZnO+2(Lysine ′HCI)->[Zn(Lysine)2CI]+CI−.(H2O)2

公开(公告)号：US09750670B2

公开(公告)日：2017-09-05

申请号：US14650898

申请日：2013-11-07

Applicant: Colgate-Palmolive Company

Inventor： Long Pan ,  Shaotang Yuan ,  Shiri Nawrocki

IPC: A61K8/44 ,  A61K8/27 ,  A61Q15/00 ,  A61Q19/10 ,  A61Q19/00 ,  A61Q11/00 ,  A61Q17/00

CPC classification number: A61K8/27 ,  A61K8/44 ,  A61K8/442 ,  A61K8/447 ,  A61K2800/58 ,  A61K2800/5922 ,  A61Q11/00 ,  A61Q15/00 ,  A61Q17/005 ,  A61Q19/00 ,  A61Q19/10

Abstract: Provided are compositions, e.g., oral and personal care products, comprising (i) a tetrabasic zinc-amino acid or trialkyl glycine-halide complex, and (ii) cysteine in free or in orally or cosmetically acceptable salt form, together with methods of making and using the same.

公开(公告)号：US20150342851A1

公开(公告)日：2015-12-03

申请号：US14653896

申请日：2013-11-07

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： Zhiqiang Liu ,  Long Pan ,  Joseph Convery ,  Shaotang Yuan ,  Harsh M. Trivedi

IPC: A61K8/58 ,  A61Q11/00 ,  A61Q19/10 ,  A61Q19/00 ,  A61K8/46 ,  A61Q15/00

CPC classification number: A61Q11/00 ,  A61K8/20 ,  A61K8/27 ,  A61K8/44 ,  A61K8/46 ,  A61K2800/58 ,  A61K2800/882 ,  A61Q15/00 ,  A61Q19/10

Abstract: Provided are compositions, e.g., oral and personal care products, comprising (i) a zinc (amino acid or trialkyl glycine) halide complex, and (ii) cysteine in free or in orally or cosmetically acceptable salt form, together with methods of making and using the same.

Abstract translation: 提供的是组合物，例如口服和个人护理产品，其包含（i）锌（氨基酸或三烷基甘氨酸）卤化物配合物，和（ii）游离或口服或化妆品可接受的盐形式的半胱氨酸，以及制备和 使用相同

公开(公告)号：US20150335553A1

公开(公告)日：2015-11-26

申请号：US14653314

申请日：2012-12-19

Applicant: Colgate-Palmolive Company

Inventor： Long Pan ,  Jairajh Mattai ,  Shaotang Yuan ,  James G. Masters

IPC: A61K8/44 ,  A61K8/27 ,  A61Q11/00 ,  A61Q19/10 ,  A61Q17/00 ,  A61Q5/02 ,  A61Q5/12 ,  C07F3/06 ,  A61Q15/00

CPC classification number: A61K8/27 ,  A61K8/44 ,  A61K2800/58 ,  A61K2800/591 ,  A61Q5/02 ,  A61Q5/12 ,  A61Q11/00 ,  A61Q15/00 ,  A61Q17/005 ,  A61Q19/10 ,  C07B2200/13 ,  C07F3/06

Abstract: The invention provides a zinc-lysine complex having the formula [Zn(C6H14N2O2)2Cl]+ Cl− having antibacterial and antiperspirant properties, together with personal care compositions comprising the complex, and methods of making and using these complexes and compositions. The application discloses a general reaction for formation of such complexes by mixing a Zn source with Lysine in 1:2 ratio: ZnO+2 (Lysine ‘HCI)—>[Zn(Lysine)2CI] +CI−·(H2O)2

Abstract translation: 本发明提供具有抗菌和止汗性质的式[Zn（C 6 H 14 N 2 O 2）2 Cl] + Cl-的锌 - 赖氨酸配合物，以及包含该复合物的个人护理组合物，以及制备和使用这些复合物和组合物的方法。 本申请公开了通过将Zn源与赖氨酸以1:2的比例混合形成这种络合物的一般反应：ZnO + 2（赖氨酸HCl）→[Zn（赖氨酸）2 Cl] + Cl-·（H 2 O）2

公开(公告)号：US20150306008A1

公开(公告)日：2015-10-29

申请号：US14650907

申请日：2013-11-07

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： Shaotang Yuan ,  Long Pan ,  Laurence D. Du-Thumm

IPC: A61K8/58 ,  A61Q11/00 ,  A61Q15/00 ,  A61Q19/10 ,  A61K8/46

CPC classification number: A61Q11/00 ,  A61K8/27 ,  A61K8/44 ,  A61K8/447 ,  A61K31/198 ,  A61K31/555 ,  A61K33/16 ,  A61K33/30 ,  A61K2800/58 ,  A61Q15/00 ,  A61Q19/10 ,  A61K2300/00

Abstract: Provided are compositions, e.g., oral and personal care products, comprising (i) a zinc amino acid halide complex, and (ii) cysteine in free or in orally or cosmetically acceptable salt form, together with methods of making and using the same.

Abstract translation: 提供了组合物，例如口服和个人护理产品，其包含（i）锌氨基酰卤络合物，和（ii）游离或口服或化妆品可接受的盐形式的半胱氨酸，以及制备和使用它们的方法。

公开(公告)号：US11446231B2

公开(公告)日：2022-09-20

申请号：US16715237

申请日：2019-12-16

Applicant: Colgate-Palmolive Company

Inventor： Shaotang Yuan ,  Guofeng Xu ,  Junhong Mao

IPC: A61K8/91 ,  A61Q11/00 ,  A61K8/04 ,  A61K8/34 ,  A61K8/37 ,  A61K8/81 ,  A61K8/86 ,  A61K8/90

Abstract: An oral care composition and methods for preparing the oral care composition are disclosed. The oral care composition may include a carrier and a structure-building agent. The carrier may be present in an amount of from about 0.01 wt % to about 99 wt %. The structure-building agent may include a polyvinyl capralactam-polyvinyl acetate-polyethylene glycol graft copolymers (PCA-PVA-PEG), and may be present in an amount of from about 0.01 wt % to about 60 wt %, based on a total weight of the oral care composition.

公开(公告)号：US11090243B2

公开(公告)日：2021-08-17

申请号：US16722172

申请日：2019-12-20

Applicant: Colgate-Palmolive Company

Inventor： Shaotang Yuan ,  Guofeng Xu ,  Robert DiCosimo ,  Sharon L. Haynie

IPC: A61K8/37 ,  A61K8/81 ,  A61Q11/00 ,  A61K8/90

Abstract: An oral care composition, including a non-aqueous dispersant and an amphiphilic copolymer structure-building agent.

公开(公告)号：US11033475B2

公开(公告)日：2021-06-15

申请号：US16564693

申请日：2019-09-09

Applicant: Colgate-Palmolive Company

Inventor： Shaotang Yuan ,  Guofeng Xu ,  Jennifer Gronlund ,  Robert Dicosimo ,  Sharon Haynie ,  Mark Payne

IPC: A61K8/66 ,  A61K8/22 ,  A61K8/37 ,  A61K8/81 ,  A61K8/90 ,  A61Q11/00 ,  A61K8/25 ,  A61K8/86

Abstract: An oral care composition including an enzyme and an anhydrous matrix that at least partially stabilizes the enzyme. The anhydrous matrix includes a source of hydrogen peroxide, an acyl donor, a non-aqueous anhydrous liquid, and a thickener.

公开(公告)号：US10426719B2

公开(公告)日：2019-10-01

申请号：US15838916

申请日：2017-12-12

Applicant: Colgate-Palmolive Company

Inventor： Shaotang Yuan ,  Guofeng Xu ,  Jennifer Gronlund ,  Robert Dicosimo ,  Sharon Haynie ,  Mark S. Payne

IPC: A61K8/66 ,  A61K8/86 ,  A61K8/25 ,  A61Q1/00 ,  A61K8/81 ,  A61K8/22 ,  A61K8/90 ,  A61K8/37 ,  A61Q11/00

Abstract: An oral care composition including an enzyme and an anhydrous matrix that at least partially stabilizes the enzyme. The anhydrous matrix includes a source of hydrogen peroxide, an acyl donor, a non-aqueous anhydrous liquid, and a thickener.