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公开(公告)号：US10398538B2
公开(公告)日：2019-09-03
申请号：US14709140
申请日：2015-05-11
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor： John J. Gatzemeyer , Elizabeth K. Gittins , Eduardo Jimenez , Sharon Kennedy , Harsh M. Trivedi
Abstract: A method of monitoring oral health including deriving a health profile of a user from information obtained from a sample taken from the user; displaying a representation of the health profile on a display, wherein the representation of the health profile includes a list of undesirable oral health characteristics that are detectable from the sample and a graphical depiction of an oral cavity divided into a plurality of regions; and wherein in response to selection of a first one of the undesirable oral health characteristics, the representation of the health profile indicates which regions of the user's oral cavity are affected by the first one of the undesirable oral health characteristic.
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公开(公告)号：US09823236B2
公开(公告)日：2017-11-21
申请号：US14441962
申请日：2012-12-21
Applicant: Colgate-Palmolive Company
Inventor： Zhigang Hao , Deborah A. Peru , Joe Vazquez , Jessica Monk , Harsh M. Trivedi , Paul Joseph Vincenti , Osman Khalid , Ariel Haskel
CPC classification number: G01N33/497 , A61K8/24 , A61K8/33 , A61K8/35 , A61K8/4913 , A61K8/4973 , A61K2800/591 , A61Q11/00
Abstract: The present invention relates to a method for testing oral malodor, in particular oral malodor from coffee. Described herein are methods for testing the efficacy of an oral care composition to reduce oral malodor, the method comprising the steps of: a) cleaning at least a part of the oral cavity with an oral care composition; b) testing a sample of exhaled breath from the cleaned oral cavity to provide a test result representing a amount of at least one oral malodor component detected in the exhaled breath; c) exposing the oral cavity to an oral malodor material including or capable of forming the at least one oral malodor component; and d) testing a sample of exhaled breath from the oral cavity to provide a test result representing an amount of the at least one oral malodor component detected in the exhaled breath.
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3.发明申请TWO COMPONENT COMPOSITIONS CONTAINING TETRABASIC ZINC-AMINO ACID HALIDE COMPLEXES AND CYSTEINE 有权含有四羧酸锌盐酸盐复合物和CYSTEINE的两种组分公开(公告)号：US20160030319A1
公开(公告)日：2016-02-04
申请号：US14653901
申请日：2013-11-07
Applicant: Colgate-Palmolive Company
Inventor： Zhiqiang Liu , Long Pan , Joseph Convery , Shaotang Yuan , Harsh M. Trivedi
CPC classification number: A61K8/447 , A61K8/27 , A61K8/345 , A61K8/44 , A61K2800/58 , A61K2800/5922 , A61K2800/882 , A61Q11/00 , A61Q15/00 , A61Q17/005 , A61Q19/00 , A61Q19/10
Abstract: Provided are compositions, e.g., oral and personal care products, comprising (i) a tetrabasic zinc-amino acid or trialkyl glycine-halide complex, and (ii) cysteine in free or in orally or cosmetically acceptable salt form, together with methods of making and using the same.
Abstract translation: 提供了组合物，例如口服和个人护理产品，其包含（i）四碱基锌 - 氨基酸或三烷基甘氨酸 - 卤化物配合物，和（ii）游离或口服或化妆品可接受的盐形式的半胱氨酸，以及制备方法 并使用相同的。
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公开(公告)号：US09138384B2
公开(公告)日：2015-09-22
申请号：US14138450
申请日：2013-12-23
Applicant: Colgate-Palmolive Company
Inventor： Thomas Boyd , Guisheng Pan , Harsh M. Trivedi , Wei Wang , Nora Lin
CPC classification number: A61K8/0237 , A61K8/345 , A61K8/731 , A61K2800/42 , A61K2800/436 , A61Q11/00 , A61Q19/10 , B32B23/04 , B32B23/14 , B32B2307/402 , B32B2307/4026 , B32B2307/41 , B32B2307/414 , B32B2307/716 , B32B2555/00 , C11D17/06
Abstract: The invention relates to personal care products containing multilayer films with decorative layers and may impart a noticeable color change. The invention is applicable in products including type toothpaste, soaps, and other products until diluted with water (or saliva).
Abstract translation: 本发明涉及含有具有装饰层的多层膜的个人护理产品，并且可以赋予明显的颜色变化。 本发明适用于包括牙膏，肥皂等产品在内的产品，直至用水（或唾液）稀释。
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公开(公告)号：US10357438B2
公开(公告)日：2019-07-23
申请号：US15529635
申请日：2015-12-15
Applicant: Colgate-Palmolive Company
Inventor： Stanislav Jaracz , Harsh M. Trivedi , Lyndsay Schaeffer-Korbylo
Abstract: The disclosure provides oral care compositions comprising zinc ions and citrate ions with molar ratios which unexpectedly high zinc bioavailability, together with methods of preparing and using the same.
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Patent Agency Ranking
公开(公告)号：US09700395B2
公开(公告)日：2017-07-11
申请号：US14547273
申请日：2014-11-19
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor： Douglas Hohlbein , Elizabeth Gittins , Harsh M. Trivedi , Sharon Kennedy , Madhusudan Patel , Deborah Peru
IPC: G01N21/75 , A61C19/04 , A46B11/00 , A46B15/00 , A46B17/08 , A61B10/00 , A61C15/02 , A61C19/06 , G01N33/543 , A61K6/00 , A61C17/00
CPC classification number: A61C19/04 , A46B11/001 , A46B15/0002 , A46B15/0055 , A46B17/08 , A46B2200/1066 , A61B10/0051 , A61B2010/0006 , A61C15/02 , A61C17/005 , A61C19/063 , A61K6/00 , A61K6/0002 , G01N33/54353 , G01N33/5436
Abstract: The present invention relates to devices and systems for detecting the existence of oral conditions. In one aspect, the invention is a device including a detector capable of detecting a marker of an oral condition; a self-contained indicator that is actuated by a signal from the detector, wherein the indicator is one of a structural indicator adapted to undergo a physical change that is haptically perceptible, a dye adapted to be released into a user's mouth, and a flavor adapted to be released into a user's mouth; and wherein said device is detachably securable to an oral care implement.
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公开(公告)号：US09675823B2
公开(公告)日：2017-06-13
申请号：US14653896
申请日：2013-11-07
Applicant: Colgate-Palmolive Company
Inventor： Zhiqiang Liu , Long Pan , Joseph Convery , Shaotang Yuan , Harsh M. Trivedi
CPC classification number: A61Q11/00 , A61K8/20 , A61K8/27 , A61K8/44 , A61K8/46 , A61K2800/58 , A61K2800/882 , A61Q15/00 , A61Q19/10
Abstract: Provided are compositions, e.g., oral and personal care products, comprising (i) a zinc (amino acid or trialkyl glycine) halide complex, and (ii) cysteine in free or in orally or cosmetically acceptable salt form, together with methods of making and using the same.
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8.发明授权Two component compositions containing tetrabasic zinc-amino acid halide complexes and cysteine 有权含有四价锌 - 氨基酸卤化物配合物和半胱氨酸的两组分组合物公开(公告)号：US09498421B2
公开(公告)日：2016-11-22
申请号：US14653901
申请日：2013-11-07
Applicant: Colgate-Palmolive Company
Inventor： Zhiqiang Liu , Long Pan , Joseph Convery , Shaotang Yuan , Harsh M. Trivedi
IPC: A61K47/48 , A61K33/30 , A61K31/198 , A61K45/06 , A61Q11/00 , A61Q19/00 , A61K8/44 , A61Q15/00 , A61Q17/00 , A61Q19/10 , A61K8/27 , A61K8/34
CPC classification number: A61K8/447 , A61K8/27 , A61K8/345 , A61K8/44 , A61K2800/58 , A61K2800/5922 , A61K2800/882 , A61Q11/00 , A61Q15/00 , A61Q17/005 , A61Q19/00 , A61Q19/10
Abstract: Provided are compositions, e.g., oral and personal care products, comprising (i) a tetrabasic zinc-amino acid or trialkyl glycine-halide complex, and (ii) cysteine in free or in orally or cosmetically acceptable salt form, together with methods of making and using the same.
Abstract translation: 提供了组合物，例如口服和个人护理产品，其包含（i）四碱基锌 - 氨基酸或三烷基甘氨酸 - 卤化物配合物，和（ii）游离或口服或化妆品可接受的盐形式的半胱氨酸，以及制备方法 并使用相同的。
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公开(公告)号：US20150293075A1
公开(公告)日：2015-10-15
申请号：US14441962
申请日：2012-12-21
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor： Zhigang Hao , Deborah A. Peru , Joe Vazquez , Jessica Monk , Harsh M. Trivedi , Paul Joseph Vincenti , Osman Khalid , Ariel Haskel
IPC: G01N33/497 , A61K8/33 , A61K8/35 , A61Q11/00 , A61K8/24
CPC classification number: G01N33/497 , A61K8/24 , A61K8/33 , A61K8/35 , A61K8/4913 , A61K8/4973 , A61K2800/591 , A61Q11/00
Abstract: The present invention relates to a method for testing oral malodor, in particular oral malodor from coffee. Described herein are methods for testing the efficacy of an oral care composition to reduce oral malodor, the method comprising the steps of: a) cleaning at least a part of the oral cavity with an oral care composition; b) testing a sample of exhaled breath from the cleaned oral cavity to provide a test result representing a amount of at least one oral malodor component detected in the exhaled breath; c) exposing the oral cavity to an oral malodor material including or capable of forming the at least one oral malodor component; and d) testing a sample of exhaled breath from the oral cavity to provide a test result representing an amount of the at least one oral malodor component detected in the exhaled breath.
Abstract translation: 本发明涉及一种用于测试口腔恶臭，特别是咖啡口服恶臭的方法。 本文描述了用于测试口腔护理组合物降低口腔恶臭的功效的方法，该方法包括以下步骤：a）用口腔护理组合物清洁至少一部分口腔; b）从清洁的口腔测试呼出的呼吸样品，以提供表示在呼出气中检测到的至少一种口腔恶臭成分的量的测试结果; c）将口腔暴露于包含或能够形成至少一种口腔恶臭成分的口腔恶臭物质; 以及d）从口腔测试呼出的呼吸样品，以提供表示在呼出气中检测到的至少一种口腔恶臭成分的量的测试结果。
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公开(公告)号：US20160178617A1
公开(公告)日：2016-06-23
申请号：US14580485
申请日：2014-12-23
Applicant: Colgate-Palmolive Company
Inventor： Stanislav Jaracz , Harsh M. Trivedi , Lyndsay Schaeffer-Korbylo , Lynette Zaidel
CPC classification number: G01N33/5082 , G01N21/78 , G01N33/84
Abstract: An in vitro method for determining the bioavailability of zinc (II) ions from an oral care composition comprises: providing a sample comprising, the oral care composition; contacting the sample with a biorelevant substrate, separating the biorelevant substrate from the sample., contacting the biorelevant substrate with an indicator under conditions selected such that the indicator is capable of reacting with zinc (II) ions, and determining a light absorbance of the indicator. The indicator is zincon or a salt thereof. The method is useful for estimating the ability of an oral care composition to deliver therapeutically-active zinc (II) ions to the oral cavity. Also provided is the use of zincon and a biorelevant substrate in vitro to determine the bioavailability of zinc (II) ions from an oral care composition comprising, a zinc source.
Abstract translation: 用于测定来自口腔护理组合物的锌（II）离子的生物利用度的体外方法包括：提供包含口腔护理组合物的样品; 将样品与生物相关底物接触，将生物相关底物与样品分离;在选择的条件下使生物相关底物与指示剂接触，使得指示剂能够与锌（II）离子反应，并确定指示剂的吸光度 。 指示剂是钦康或其盐。 该方法可用于估计口腔护理组合物将治疗活性的锌（II）离子递送至口腔的能力。 还提供了在体外使用锌康和生物相关底物来确定来自包含锌源的口腔护理组合物的锌（II）离子的生物利用度。
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