公开(公告)号：US20060069088A1

公开(公告)日：2006-03-30

申请号：US11129512

申请日：2005-05-13

申请人： Stephen Goble ,  Sander Mills ,  Lihu Yang ,  Alexander Pasternak ,  Celine Bonnefous ,  Theodore Kamenecka ,  Jean-Michel Vernier ,  John Hutchinson ,  Essa Hu ,  Steven Govek

发明人： Stephen Goble ,  Sander Mills ,  Lihu Yang ,  Alexander Pasternak ,  Celine Bonnefous ,  Theodore Kamenecka ,  Jean-Michel Vernier ,  John Hutchinson ,  Essa Hu ,  Steven Govek

IPC分类号： A61K31/542 ,  A61K31/538 ,  A61K31/519 ,  C07D498/02 ,  C07D487/02 ,  C07D491/02

CPC分类号： C07D413/08 ,  C07D413/14 ,  C07D417/14

摘要： Cyclopentyl compounds linked to a benzoxazinyl group through an amido moiety utilizing the ring nitrogen of the benzoxazine, and further substituted with a heterocyclic moiety, such compounds represented by formula I: which are used to modulate the CCR-2 chemokine receptor to prevent or treat inflammatory and immunoregulatory disorders and diseases, allergic diseases, atopic conditions including allergic rhinitis, dermatitis, conjunctivitis, and asthma, as well as autoimmune pathologies such as rheumatoid arthritis and atherosclerosis; and pharmaceutical compositions comprising these compounds and the use of these compounds and compositions.

摘要翻译： 通过使用苯并恶嗪的环氮通过酰胺部分连接到苯并恶嗪基的环戊基化合物，并进一步被杂环部分取代，由式I表示的化合物：

公开(公告)号：US06617082B2

公开(公告)日：2003-09-09

申请号：US09895696

申请日：2001-06-29

申请人： John Hutchinson

发明人： John Hutchinson

IPC分类号： G03F900

CPC分类号： B82Y10/00 ,  B82Y40/00 ,  G03F1/24 ,  G03F7/70291

摘要： The present invention discloses a microelectromechanical system mask with an array of reflectors, each reflector having two mirrors separated from each other by an adjustable gap.

摘要翻译： 本发明公开了一种具有反射器阵列的微机电系统掩模，每个反射器具有通过可调间隙彼此分离的两个反射镜。

公开(公告)号：US6085937A

公开(公告)日：2000-07-11

申请号：US012009

申请日：1998-01-22

申请人： John Hutchinson ,  William Fulwiler

发明人： John Hutchinson ,  William Fulwiler

IPC分类号： A63B47/00 ,  G07F11/54 ,  G07F11/00 ,  B65G59/00

CPC分类号： A63B47/002 ,  G07F11/54 ,  A63B2225/70

摘要： Disclosed is a coin operated vending machine for individual golf ball or similarly sized product, includes a rotating carousel for holding stacks of product within a housing with an enclosed main display compartment and a slide assembly for dispensing product from the carousel into a dispensing area. A carousel including a plurality of vertical guides for containing a stacked array of individual golf ball units therein, is rotatably supported within the main display compartment such that each of the guides is selectively positional in vertical alignment over a drop hole below the slide assembly, the drop hole being sized and configured to receive an individual, lower most product unit dropped from the aligned guide. A conventional type coin released lock mechanism is provided which is structured to accept coins to release the slide assembly for inward movement to the extended position, causing the individual golf ball product within the drop hole to be carried from below the aligned guide to a drop chute where it is deposited thereon and dispensed to the user.

摘要翻译： 公开了一种用于单独的高尔夫球或类似尺寸的产品的投币式自动售货机，包括旋转的转盘，用于将具有封闭的主显示室和用于将转盘中的产品分配到分配区域中的滑动组件的产品的堆叠物保持在壳体内。 包括多个用于在其中容纳各个高尔夫球单元的堆叠阵列的垂直引导件的转盘被可旋转地支撑在主显示室内，使得每个引导件选择性地位于垂直对准位于滑动组件下方的下落孔上， 放置孔的尺寸和构造用于接收从对齐的导板下降的单个的，最低的产品单元。 提供了一种常规型的硬币释放锁定机构，其构造成接收硬币以释放滑动组件以向内移动到延伸位置，使得滴液孔内的各个高尔夫球产品从对准的引导件的下方承载到落下滑槽 在其上沉积并分配给用户。

公开(公告)号：US10068266B2

公开(公告)日：2018-09-04

申请号：US13309109

申请日：2011-12-01

申请人： John Hutchinson ,  Venkateswaran Krishnan ,  Senthilkumar Vadivel

发明人： John Hutchinson ,  Venkateswaran Krishnan ,  Senthilkumar Vadivel

IPC分类号： G06Q30/00 ,  G06Q30/06

摘要： Disclosed embodiments provide an electronic procurement system and process that enables a buyer or purchasing organization to maintain explicitly or implicitly, a contract price between the buyer/purchasing organization and the supplier whose catalog is integrated with an electronic marketplace. In one embodiment, a process is executed that compares the listed/purchase price of catalog items against the contract price or against a ‘normal’ purchase price. A user (e.g. the buyer) may configure and receive specific alerts regarding items that are purchased in deviation of contracted price and items that have been added to the catalog since the last contract. Disclosed embodiments may also maintain, automatically, the historical price and purchase information of supplier catalog items that are enabled through the electronic marketplace.

公开(公告)号：US20120143725A1

公开(公告)日：2012-06-07

申请号：US13309069

申请日：2011-12-01

申请人： John Hutchinson ,  Venkateswaran Krishnan ,  Senthilkumar Vadivel

发明人： John Hutchinson ,  Venkateswaran Krishnan ,  Senthilkumar Vadivel

IPC分类号： G06Q30/00

CPC分类号： G06Q30/0625 ,  G06Q30/0603

摘要： Disclosed embodiments relate to an electronic procurement tool that enables the buyer, or purchasing organization, on a near real-time basis, to review or influence the search and purchasing patterns from the supplier(s) catalogs that are enabled through an electronic marketplace using priorities, specified ranks, and promotions. In one aspect, the disclosed systems and methods may allow users to view supplier catalog items that are more relevant to their search criteria and/or that comply with an organization's contract with a supplier. It may also allow users to view popular items in terms of purchase frequency and the average/relevant purchase price or transparently in terms of the preference of the purchasing organization.

摘要翻译： 公开的实施例涉及一种电子采购工具，其使买方或采购组织能够在几乎实时的基础上审查或影响来自供应商目录的搜索和购买模式，这些目录通过电子市场使用优先级 ，指定排名和促销。 一方面，所公开的系统和方法可以允许用户查看与其搜索标准更相关的供应商目录项目和/或符合组织与供应商的合同。 它还可以允许用户根据购买频率和平均/相关购买价格来查看受欢迎的商品，或者根据采购组织的偏好来透明地查看热门商品。

公开(公告)号：US20110003815A1

公开(公告)日：2011-01-06

申请号：US12682150

申请日：2008-10-06

申请人： Anthony Ogawa ,  Feroze Ujjainwalla ,  Bing Li ,  Lin Chu ,  Minal Patel ,  Helen M. Armstrong ,  Hyun O. Ok ,  Rosemary Sisco ,  Dwight MacDonald ,  John Hutchinson ,  Helene Perrier

发明人： Anthony Ogawa ,  Feroze Ujjainwalla ,  Bing Li ,  Lin Chu ,  Minal Patel ,  Helen M. Armstrong ,  Hyun O. Ok ,  Rosemary Sisco ,  Dwight MacDonald ,  John Hutchinson ,  Helene Perrier

IPC分类号： A61K31/5377 ,  C07D401/14 ,  C07D413/12 ,  C07D211/68 ,  C07D417/12 ,  C07D403/12 ,  A61K31/4439 ,  A61K31/444 ,  A61K31/501 ,  A61P9/10

CPC分类号： C07D401/12 ,  C07D213/30 ,  C07D213/55 ,  C07D213/56 ,  C07D237/20 ,  C07D239/26 ,  C07D277/24 ,  C07D401/14 ,  C07D403/04 ,  C07D403/12 ,  C07D403/14 ,  C07D413/10 ,  C07D413/12 ,  C07D413/14 ,  C07D417/10 ,  C07D417/12 ,  C07D417/14 ,  C07D453/02

摘要： The present invention provides compounds of Formula I which are FLAP inhibitors useful as anti-atherosclerotic, anti-asthmatic, anti-allergic, anti-inflammatory and cytoprotective agents.

摘要翻译： 本发明提供了可用作抗动脉粥样硬化，抗哮喘，抗过敏，抗炎和细胞保护作用的FLAP抑制剂的式I化合物。

公开(公告)号：US20090216280A1

公开(公告)日：2009-08-27

申请号：US12365225

申请日：2009-02-04

申请人： John Hutchinson

发明人： John Hutchinson

IPC分类号： A61B17/88 ,  A61B17/86 ,  A61B17/70

CPC分类号： A61B17/88 ,  A61B17/7002 ,  A61B17/7032 ,  A61B17/7038

摘要： A method of treating a spinal column shape deformation includes fixing at least two fixation screw assemblies to respective vertebrae, sliding a rod between the arm extensions on each of the fixation screw assemblies, swinging the channels of the screw assemblies relative to the fixation screws so that the channels become less inclined to the axes of the fixation screws, and so that the rod is located generally posteriorly of the spinal column, locking the channel against swinging relative to the screw, rotating the rod about its axis relative to at least one of the channels, and locking the rod against movement relative to the channel.

摘要翻译： 治疗脊柱形变形的方法包括将至少两个固定螺钉组件固定到相应的椎骨上，在每个固定螺钉组件上的臂延伸部之间滑动杆，相对于固定螺钉摆动螺钉组件的通道，使得 通道变得不那么倾向于固定螺钉的轴线，并且使得杆大体位于脊柱的后方，锁定通道相对于螺钉摆动，相对于其中的至少一个将杆绕其轴线旋转 通道，并且锁定杆相对于通道的运动。

公开(公告)号：US20070237482A1

公开(公告)日：2007-10-11

申请号：US11394563

申请日：2006-03-31

申请人： John Hutchinson

发明人： John Hutchinson

IPC分类号： G02B6/10

CPC分类号： G02B6/131 ,  G02B6/136 ,  G02B2006/12097 ,  G02F1/025 ,  G02F1/2257 ,  G02F2001/0152 ,  H01S5/2201

摘要： According to embodiments of the present invention, an optical device includes a ridge waveguide having the ridge oriented on the waveguide core layer at an angle away from the direction of the (100) plane of (100) Indium Phosphide substrate. The ridge waveguide may be a laser diode, a Mach-Zehnder modulator, or other suitable optical device.

摘要翻译： 根据本发明的实施例，光学装置包括脊形波导，其具有在波导芯层上定向的离开（100）磷化铟基板的（100）平面的<110>方向的角度的脊。 脊形波导可以是激光二极管，马赫 - 曾德调制器或其它合适的光学器件。

公开(公告)号：US20070219206A1

公开(公告)日：2007-09-20

申请号：US11744555

申请日：2007-05-04

申请人： John Hutchinson ,  Petpiboon Prasit ,  Mark Moran ,  Jillian Evans ,  Brian Stearns ,  Jeffrey Roppe ,  Bowei Wang ,  Yen Truong ,  Yiwei Li ,  Jasmine Zunic ,  Jeannie Arruda ,  Nicholas Stock ,  Mustapha Haddach ,  Thomas Seiders ,  Jill Scott

发明人： John Hutchinson ,  Petpiboon Prasit ,  Mark Moran ,  Jillian Evans ,  Brian Stearns ,  Jeffrey Roppe ,  Bowei Wang ,  Yen Truong ,  Yiwei Li ,  Jasmine Zunic ,  Jeannie Arruda ,  Nicholas Stock ,  Mustapha Haddach ,  Thomas Seiders ,  Jill Scott

IPC分类号： A61K31/506 ,  A61K31/501 ,  A61K31/497 ,  A61K31/498 ,  A61K31/4709 ,  A61K31/4745 ,  A61K31/4439 ,  A61K31/42 ,  A61K31/428 ,  A61K31/404 ,  C07D413/02 ,  C07D403/02

CPC分类号： C07D401/12 ,  C07D401/14 ,  C07D413/14 ,  C07D417/12 ,  C07D417/14

摘要： Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of 5-lipoxygenase-activating protein (FLAP). Also described herein are methods of using such FLAP modulators, alone and in combination with other compounds, for treating respiratory, cardiovascular, and other leukotriene-dependent or leukotriene mediated conditions or diseases.

公开(公告)号：US20070052240A1

公开(公告)日：2007-03-08

申请号：US10552943

申请日：2004-04-15

申请人： John Hutchinson ,  Pierre Becker

发明人： John Hutchinson ,  Pierre Becker

IPC分类号： H02K7/18 ,  H02K7/10 ,  F02B63/04

CPC分类号： H02K7/1853 ,  H02J7/32

摘要： A pedal generator having a single foot operated pedal, and spring biased means for converting oscillatory movement of the pedal into drive for an alternator, the pedal comprises a pedal lever (2) connected to a drive shaft (3) and movable between a raised position and a lowered position so that a user can impart rotation to the drive shaft (3).

摘要翻译： 具有单脚操作踏板的踏板发生器和用于将踏板的振荡运动转换为用于交流发电机的驱动器的弹簧偏压装置，踏板包括连接到驱动轴（3）的踏板杆（2），并且可在升高位置 和降低位置，使得使用者可以向驱动轴（3）施加旋转。