公开(公告)号：US08939945B2

公开(公告)日：2015-01-27

申请号：US13497769

申请日：2010-09-29

申请人： Robert Veasey ,  David Plumptre ,  Christopher Jones ,  Garen Kouyoumjian ,  Catherine Anne MacDonald

发明人： Robert Veasey ,  David Plumptre ,  Christopher Jones ,  Garen Kouyoumjian ,  Catherine Anne MacDonald

IPC分类号： A61M5/00 ,  A61M5/315 ,  A61M5/24

CPC分类号： A61M5/31511 ,  A61M5/24 ,  A61M5/31505 ,  A61M5/31555 ,  A61M5/3156 ,  A61M5/31585 ,  A61M2005/2407

摘要： A lead screw (5) with a screw thread (6) is arranged in a body (1) along an axis (4) and coupled to a lead screw nut (7) with a drive feature (8), so that the lead screw is helically rotatable in the lead screw nut. The lead screw and the lead screw nut are provided with stop features (9) interfering with a rotation of the lead screw in the lead screw nut when a force is applied to the lead screw in an axial direction. The lead screw nut has a surface area facing a guide feature (10) of the body. This surface area has a slope (12) varying around the axis. The assembly interacts such that the lead screw nut rotates in one rotational direction when a force is applied to the lead screw in the axial direction.

摘要翻译： 具有螺纹（6）的导螺杆（5）沿着轴线（4）布置在主体（1）中并且与具有驱动特征（8）的丝杠螺母（7）连接，使得导螺杆 可在导螺杆螺母中螺旋转动。 导向螺钉和导螺杆螺母在沿轴向向导螺杆施加力时，设有阻止导螺杆螺母旋转的停止特征（9）。 导螺杆螺母具有面向主体的引导特征（10）的表面区域。 该表面区域具有围绕轴线变化的斜率（12）。 组件相互作用，使得当螺杆沿轴向施加力时，导螺杆螺母在一个旋转方向上旋转。

公开(公告)号：US20140279379A1

公开(公告)日：2014-09-18

申请号：US13804023

申请日：2013-03-14

申请人： Rami Mahdi ,  Darwin Villagomez ,  Christopher Jones

发明人： Rami Mahdi ,  Darwin Villagomez ,  Christopher Jones

IPC分类号： G06Q40/02

CPC分类号： G06Q40/025 ,  G06Q30/0609

摘要： The present invention provides, in at least one embodiment, a system, and method for detecting first party fraud. When a fraudulent consumer fills out a current application for a discounted commodity, such as cell phone, the system searches for prior applications with the same or similar (i.e., matching) identity information. Based on these matches (i.e., identity linking keys), the system generates marker variables indicative of first party fraud. For example, markers can be the number of matching applications filed for a commodity within a given time period. Lastly, the system outputs a risk score based on the markers. The risk score represents the chance that the current application represents first party fraud.

摘要翻译： 本发明在至少一个实施例中提供了一种用于检测第一方欺诈的系统和方法。 当欺诈性消费者填写诸如手机的折扣商品的当前申请时，系统搜索具有相同或相似（即，匹配）身份信息的先前申请。 基于这些匹配（即，身份链接密钥），系统生成指示第一方欺诈的标记变量。 例如，标记可以是给定时间段内为商品提交的匹配应用的数量。 最后，系统根据标记输出风险分数。 风险分数表示当前应用程序代表第一方欺诈的机会。

公开(公告)号：US08512285B2

公开(公告)日：2013-08-20

申请号：US13392778

申请日：2010-09-15

申请人： Ulrich Bruggemann ,  Christopher Jones

发明人： Ulrich Bruggemann ,  Christopher Jones

IPC分类号： A61M37/00

CPC分类号： A61M5/14546 ,  A61M2205/14

摘要： Latching and control unit for integration in a medical device for infusion of a medicament or removal of a substance of a human body by a drive means, the latching and control unit being adapted for controlling the movement of at least a first and a second movable component, the latching and control unit including a drive train, a detection device, coupling means, and a control device.

摘要翻译： 用于集成在用于通过驱动装置输注药物或人体物质的医疗装置的锁存和控制单元，所述闩锁和控制单元适于控制至少第一和第二可移动部件 锁定和控制单元包括传动系，检测装置，联接装置和控制装置。

公开(公告)号：US20120296287A1

公开(公告)日：2012-11-22

申请号：US13497769

申请日：2010-09-29

申请人： Robert Veasey ,  David Plumptre ,  Christopher Jones ,  Garen Kouyoumjian ,  Catherine Anne MacDonald

发明人： Robert Veasey ,  David Plumptre ,  Christopher Jones ,  Garen Kouyoumjian ,  Catherine Anne MacDonald

IPC分类号： A61M5/315 ,  A61M5/31

CPC分类号： A61M5/31511 ,  A61M5/24 ,  A61M5/31505 ,  A61M5/31555 ,  A61M5/3156 ,  A61M5/31585 ,  A61M2005/2407

摘要： A lead screw (5) with a screw thread (6) is arranged in a body (1) along an axis (4) and coupled to a lead screw nut (7) with a drive feature (8), so that the lead screw is helically rotatable in the lead screw nut. The lead screw and the lead screw nut are provided with stop features (9) interfering with a rotation of the lead screw in the lead screw nut when a force is applied to the lead screw in an axial direction. The lead screw nut has a surface area facing a guide feature (10) of the body. This surface area has a slope (12) varying around the axis. The assembly interacts such that the lead screw nut rotates in one rotational direction when a force is applied to the lead screw in the axial direction.

摘要翻译： 具有螺纹（6）的导螺杆（5）沿着轴线（4）布置在主体（1）中并且与具有驱动特征（8）的丝杠螺母（7）连接，使得导螺杆 可在导螺杆螺母中螺旋转动。 导向螺钉和导螺杆螺母在沿轴向向导螺杆施加力时，设有阻止导螺杆螺母旋转的停止特征（9）。 导螺杆螺母具有面向主体的引导特征（10）的表面区域。 该表面区域具有围绕轴线变化的斜率（12）。 组件相互作用，使得当螺杆沿轴向施加力时，导螺杆螺母在一个旋转方向上旋转。

公开(公告)号：US20120283657A1

公开(公告)日：2012-11-08

申请号：US13496537

申请日：2010-09-29

申请人： Garen Kouyoumjian ,  Robert Veasey ,  David Plumptre ,  Christopher Jones ,  Catherine Anne Macdonald ,  Matthew Jones

发明人： Garen Kouyoumjian ,  Robert Veasey ,  David Plumptre ,  Christopher Jones ,  Catherine Anne Macdonald ,  Matthew Jones

IPC分类号： A61M5/315 ,  B23P17/04

CPC分类号： A61M5/31585 ,  A61M5/24 ,  A61M5/3146 ,  A61M5/31555 ,  A61M5/3158 ,  A61M2005/2407 ,  A61M2205/6081 ,  A61M2207/00 ,  Y10T29/49826

摘要： The present invention relates to an assembly forming a piston rod for advancing a cartridge bung in a drug delivery device, the assembly comprising a first member and a second member wherein in a first state, the first and the second member are moveable with respect to each other to adjust the length of the piston rod and wherein in a second state the first member is locked in position with respect to the second member in order to define a fixed length of the piston rod. Furthermore, it relates to a drug delivery device comprising the assembly and to a method for assembling such a drug delivery device.

摘要翻译： 本发明涉及一种形成活塞杆的组件，该活塞杆用于推进药物输送装置中的筒塞，该组件包括第一构件和第二构件，其中在第一状态下，第一和第二构件可相对于每个构件移动 另一个调节活塞杆的长度，并且其中在第二状态下，第一构件相对于第二构件被锁定就位，以便限定活塞杆的固定长度。 此外，本发明涉及一种药物递送装置，其包括该组件以及用于组装这种药物递送装置的方法。

公开(公告)号：US20120283651A1

公开(公告)日：2012-11-08

申请号：US13395599

申请日：2010-09-29

申请人： Robert Veasey ,  Simon Lewis Bilton ,  Christopher Jones ,  Garen Kouyoumjian ,  Catherine Anne MacDonald

发明人： Robert Veasey ,  Simon Lewis Bilton ,  Christopher Jones ,  Garen Kouyoumjian ,  Catherine Anne MacDonald

IPC分类号： A61M5/315

CPC分类号： A61M5/31543 ,  A61M5/31535 ,  A61M5/31555 ,  A61M5/3156 ,  A61M5/3158 ,  A61M5/31593 ,  A61M2005/2407

摘要： A plunger (4) having engaging means and a lever (5) are arranged in a body (1). The lever has a first pivot that is stationary with respect to the body in the direction of an axis, a second pivot, and a third pivot formed by an engaging element of the lever. The pivots are arranged in such a manner that a rotation of the lever with respect to the first pivot moves the second pivot and the third pivot in the same direction with respect to the axis. The engaging element and the engaging means are shaped such that the lever is disengaged from the plunger when the second pivot is moved relatively to the plunger in the proximal direction (30), and the plunger is engaged with the lever when the second pivot is moved in the distal direction (20).

摘要翻译： 具有接合装置和杆（5）的柱塞（4）布置在主体（1）中。 所述杠杆具有第一枢轴，所述第一枢轴在轴线方向相对于所述主体固定，第二枢轴和由所述杠杆的接合元件形成的第三枢轴。 所述枢轴以这样的方式设置，即所述杆相对于所述第一枢轴的旋转使所述第二枢轴和所述第三枢轴沿相对于所述轴线的相同方向移动。 接合元件和接合装置的形状使得当第二枢轴在近端方向（30）相对于柱塞移动时，杠杆与柱塞脱离，并且当第二枢轴移动时，柱塞与杠杆接合 在远端方向（20）。

公开(公告)号：US20120283646A1

公开(公告)日：2012-11-08

申请号：US13498372

申请日：2010-09-29

申请人： Garen Kouyoumjian ,  Robert Veasey ,  Christopher Jones ,  Catherine Anne Macdonald ,  Stephen Gilmore ,  George Cave

发明人： Garen Kouyoumjian ,  Robert Veasey ,  Christopher Jones ,  Catherine Anne Macdonald ,  Stephen Gilmore ,  George Cave

IPC分类号： A61M5/315 ,  A61M5/32

CPC分类号： A61M5/34 ,  A61M5/002 ,  A61M5/1456 ,  A61M5/2466 ,  A61M5/3146 ,  A61M5/31525 ,  A61M5/31533 ,  A61M5/31571 ,  A61M5/3202 ,  A61M5/3293 ,  A61M5/345

摘要： A drug delivery system comprises a drug delivery device which comprises a housing and a cartridge. The drug delivery device has a proximal end and a distal end. The drug delivery system further comprises a needle assembly which is attachable to the drug delivery device. The needle assembly and the drug delivery device are configured such that the cartridge is moved in the proximal direction with respect to the housing when the needle assembly is attached to the drug delivery device.

摘要翻译： 药物递送系统包括药物递送装置，其包括壳体和药筒。 药物递送装置具有近端和远端。 药物递送系统还包括可组装到药物递送装置上的针组件。 针组件和药物递送装置构造成使得当针组件附接到药物递送装置时，药筒相对于壳体在近侧方向上移动。

公开(公告)号：US20120271233A1

公开(公告)日：2012-10-25

申请号：US13392778

申请日：2010-09-15

申请人： Ulrich Bruggemann ,  Christopher Jones

发明人： Ulrich Bruggemann ,  Christopher Jones

IPC分类号： A61M5/145 ,  A61M5/142

CPC分类号： A61M5/14546 ,  A61M2205/14

摘要： Latching and control unit (1) for integration in a medical device for infusion of a medicament or removal of a substance of a human body by a drive means, the latching and control unit being adapted for controlling the movement of at least a first and a second movable component, the latching and control unit (1) comprising: a drive train (10) biased in a distant position with regard to the support device (20), wherein the drive train (10) comprises a case (13) and a latching means (17) for latching a first movable component and being movable within the case (13) between an extended and an retracted position and being biased in its latching position, wherein the case (13) is movable between an unstressed and a stressed position with regard to the support device (20) and biased into the unstressed position, wherein the elastic force for biasing the latching means (17) is greater than the elastic force for biasing the case (13), a detection device (15) for detecting a stressed position of the case (13), coupling means (13.6) for coupling of at least a partial movement of the second movable component with the movement of the case (13), a control device which is functionally connected to the detection device (15) which comprises a function for determining a stressed position of the drive train so that the control device determines the movement of the latching means (17) in its retracted position by interaction with the first component and the movement of the drive train (10) in its stressed position by interaction with the second component.

摘要翻译： 锁定和控制单元（1）用于集成在医疗装置中，用于通过驱动装置输注药物或去除人体物质，所述锁定和控制单元适于控制至少第一和第 所述锁定和控制单元（1）包括：相对于所述支撑装置（20）偏置在远离位置的传动系（10），其中所述传动系（10）包括壳体（13）和 用于锁定第一可移动部件的闩锁装置（17），并且可在所述壳体（13）内在延伸和缩回位置之间移动并且被偏置在其闩锁位置中，其中所述壳体（13）可在无应力位置和应力位置 关于支撑装置（20）并且被偏压到无应力位置，其中用于偏压闩锁装置（17）的弹力大于用于偏置壳体（13）的弹力，用于检测的检测装置（15） 一个强调的位置 壳体（13），用于将第二可移动部件的至少部分运动与壳体（13）的移动相结合的联接装置（13.6），功能上连接到检测装置（15）的控制装置，其包括 用于确定传动系的应力位置的功能，使得控制装置通过与第一部件的相互作用和传动系（10）在其应力位置的运动来确定闩锁装置（17）处于其缩回位置的运动 通过与第二组分的相互作用。

公开(公告)号：US20120165749A1

公开(公告)日：2012-06-28

申请号：US13322351

申请日：2010-05-28

申请人： Christopher Jones

发明人： Christopher Jones

IPC分类号： A61M5/31

CPC分类号： A61M5/31538 ,  A61M5/31535 ,  A61M5/31536 ,  A61M5/31541 ,  A61M5/31545 ,  A61M5/31548 ,  A61M5/3155 ,  A61M5/31551 ,  A61M5/31553 ,  A61M5/31555 ,  A61M5/31595 ,  A61M2005/3154

摘要： A maximum settable dose feature is disclosed that is set by a user or health care professional one time that prevents future injections from exceeding the desired maximum dose. The feature includes a locking band (5) initially in an unlocked configuration, which transforms to a locked configuration when activated after setting a desired maximum dose. The feature can include a trigger mechanism (6,11) to transform the locking band (5) to the locked configuration.

摘要翻译： 公开了由用户或保健专业人员设定的一次可防止未来注射超过所需最大剂量的最大可设定剂量特征。 该特征包括最初处于未锁定配置的锁定带（5），当在设定期望的最大剂量之后激活时，锁定配置变换为锁定配置。 该特征可以包括将锁定带（5）变换成锁定构造的触发机构（6,11）。

公开(公告)号：US20110230672A1

公开(公告)日：2011-09-22

申请号：US13049375

申请日：2011-03-16

申请人： Dun-Yen Kang ,  Sankar Nair ,  Christopher Jones

发明人： Dun-Yen Kang ,  Sankar Nair ,  Christopher Jones

IPC分类号： C07F7/02 ,  B82Y40/00 ,  B82Y30/00

CPC分类号： B82Y30/00 ,  B82Y40/00 ,  C01B33/26 ,  C01G1/02 ,  C01G17/00 ,  C01G53/006 ,  C01P2002/72 ,  C01P2002/82 ,  C01P2002/86 ,  C01P2002/88 ,  C01P2004/04 ,  C01P2004/13

摘要： Provided herein are methods for dehydrating single-walled metal oxide nanotubes by heating the SWNT under vacuum at 250-300° C.; methods of dehydroxylating SWNT, comprising heating the SWNT under vacuum at 300-340° C., and methods for maximizing the pore volume of a SWNT, comprising heating the SWNT at 300° C. under vacuum to partially dehydroxylate and dehydrate the SWNT; methods of modifying the inner surface of a single walled aluminosilicate nanotube (SWNT), comprising dehydration or dehydration and dehydroxylation, followed by reacting the SWNT with a derivative under anhydrous conditions to produce a SWNT that is derivatized on its inner surface. The invention also includes single-walled nanotubes produced by the methods of the invention.

摘要翻译： 本文提供了通过在250-300℃真空下加热SWNT来使单壁金属氧化物纳米管脱水的方法。 脱水氧化SWNT的方法，包括在300-340℃下真空加热SWNT，以及使SWNT的孔体积最大化的方法，包括在真空下在300℃下加热SWNT以使SWNT部分脱羟基化和脱水; 改变单壁铝硅酸盐纳米管（SWNT）的内表面的方法，包括脱水或脱水和脱羟基化，然后在无水条件下使SWNT与衍生物反应以产生在其内表面衍生的SWNT。 本发明还包括通过本发明的方法制备的单壁纳米管。