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100 条记录 (耗时 0.036 秒)

    Method for providing information of a locally resolved reconstruction quality of a target volume in a three-dimensional reconstruction volume presentation
    21.
    发明授权
    Method for providing information of a locally resolved reconstruction quality of a target volume in a three-dimensional reconstruction volume presentation 有权
    用于在三维重建体积呈现中提供目标体积的局部分辨的重建质量的信息的方法

    公开(公告)号：US08364239B2

    公开(公告)日：2013-01-29

    申请号：US11725377

    申请日：2007-03-19

    申请人： Matthias John ,  Norbert Rahn

    发明人： Matthias John ,  Norbert Rahn

    IPC分类号： A61B5/05

    CPC分类号： A61B6/032 ,  A61B8/12 ,  A61B8/5238 ,  G06T11/008

    摘要： The invention relates to a method and a device for locally-resolved visualization of the reconstruction quality, especially of the coverage of a target volume to be recorded as an image and reproduced in a three-dimensional reconstruction volume presentation, especially in the human body, by two-dimensional and/or three-dimensional images covering subareas of the volume recorded by a recording device arranged inside the target volume, with which the three-dimensional reconstruction volume presentation is created, with the subareas of the target volume covered by the individual images being determined and a visual locally-resolved presentation of the reconstruction quality, especially of the coverage, being created and output as a function of the subarea coverage.

    摘要翻译： 本发明涉及一种用于本地解析的重建质量可视化的方法和装置，特别是要被记录为图像并在三维重建体积呈现中特别是在人体中再现的目标体积的覆盖范围， 通过覆盖由配置在目标体积内的记录装置记录的体积的二维和/或三维图像，三维重建体积呈现被创建，其中目标体积的子区域由个体覆盖 图像被确定，并且重建质量，特别是覆盖范围的视觉局部解决呈现被创建并作为子区域覆盖的函数而被输出。

    Compositions and methods for inhibiting viral replication
    22.
    发明授权
    Compositions and methods for inhibiting viral replication 有权
    用于抑制病毒复制的组合物和方法

    公开(公告)号：US08273868B2

    公开(公告)日：2012-09-25

    申请号：US12631689

    申请日：2009-12-04

    申请人： Matthias John ,  Stefan Limmer ,  Hans-Peter Vornlocher ,  Roland Kreutzer

    发明人： Matthias John ,  Stefan Limmer ,  Hans-Peter Vornlocher ,  Roland Kreutzer

    IPC分类号： C07H21/04 ,  A61K31/70

    CPC分类号： C12N15/1131 ,  C12N2310/14 ,  C12N2310/53

    摘要： The present invention relates to a double-stranded ribonucleic acid (dsRNA) having a nucleotide sequence which is less that 30 nucleotides in length and which is substantially identical to at least a part of a 3′-untranslated region (3′-UTR) of a (+) strand RNA virus, such as HCV, as well as pharmaceutical compositions comprising the dsRNA, together with a pharmaceutically acceptable carrier. The pharmaceutical compositions are useful for treating infections and diseases caused by the replication or activity of the (+) strand RNA virus, as well as methods for inhibiting viral replication.

    摘要翻译： 本发明涉及具有长度小于30个核苷酸的核苷酸序列的双链核糖核酸（dsRNA），并且其基本上与3'非翻译区（3'-UTR）的至少一部分相同 （+）链RNA病毒，例如HCV，以及包含dsRNA的药物组合物，以及药学上可接受的载体。 药物组合物可用于治疗由（+）链RNA病毒的复制或活性引起的感染和疾病以及用于抑制病毒复制的方法。

    Optoelectronic detector assembly and method of operating same
    23.
    发明授权
    Optoelectronic detector assembly and method of operating same 有权
    光电检测器组件及其操作方法

    公开(公告)号：US08253093B2

    公开(公告)日：2012-08-28

    申请号：US12849967

    申请日：2010-08-04

    申请人： Mirko Liedtke ,  Matthias John

    发明人： Mirko Liedtke ,  Matthias John

    IPC分类号： H01J7/24 ,  G01J5/02 ,  G01N19/00 ,  G01N7/00 ,  F24F3/14

    CPC分类号： G02B21/362 ,  G01J1/02 ,  G01J1/0252 ,  G02B7/008 ,  G02B21/28

    摘要： An optoelectronic detector and method of using same. In order to avoid any condensation on a surface, it has been known to heat such a surface. However, heating an optoelectronic detector will create a stronger hissing noise due to the greater dark current that is caused thereby. The invention is intended to avoid any condensation on an optoelectronic detector without airtight encapsulation. To this end, the detector is cooled and equipped with a sensor for the determination of a current value of one of the variables ambient humidity and ambient dew point temperature and a control unit that is connected with the sensor and designed to control the cooling device in dependence of such a value. By taking into account the ambient humidity or, respectively, the dew point temperature in the control of the cooling device, condensation on the detector can be avoided. An airtight encapsulation of the detector and the cooling device is not required.

    摘要翻译： 一种光电检测器及其使用方法。 为了避免表面上的任何冷凝，已知加热这种表面。 然而，由于由此引起的较大的暗电流，加热光电检测器将产生更强的嘶嘶声。 本发明旨在避免在没有气密封装的情况下在光电检测器上的任何冷凝。 为此，检测器被冷却并配备有用于确定环境湿度和环境露点温度之一的变量的当前值的传感器，以及与传感器连接并被设计成控制冷却装置的控制单元 这种价值的依赖。 通过考虑环境湿度或分别控制冷却装置的露点温度，可以避免检测器上的冷凝。 不需要检测器和冷却装置的气密封装。

    Ultra wide band antenna with a spline curve radiating element
    24.
    发明授权
    Ultra wide band antenna with a spline curve radiating element 有权
    带有花键曲线辐射元件的超宽带天线

    公开(公告)号：US08232922B2

    公开(公告)日：2012-07-31

    申请号：US12355592

    申请日：2009-01-16

    申请人： Max Ammann ,  Matthias John

    发明人： Max Ammann ,  Matthias John

    IPC分类号： H01Q1/38

    CPC分类号： H01Q9/30 ,  H01Q9/40 ,  H01Q9/42 ,  Y10T29/49016

    摘要： The present application relates to microstrip-fed printed planar antennas and in particular to the geometry of same. More particularly an antenna is provided with a radiating or ground plane element having a generally continuous curved shape and being symmetrical about the longitudinal axis and non-symmetrical about an axis transverse to the longitudinal axis.

    摘要翻译： 本申请涉及微带馈送印刷平面天线，特别涉及其几何形状。 更具体地说，天线设置有辐射或接地平面元件，其具有大致连续的弯曲形状并且围绕纵向轴线对称并且关于横向于纵向轴线的轴线是不对称的。

    Device for merging a 2D radioscopy image with an image from a 3D image data record
    26.
    发明授权
    Device for merging a 2D radioscopy image with an image from a 3D image data record 有权
    用于将2D放射成像图像与来自3D图像数据记录的图像合并的装置

    公开(公告)号：US08045780B2

    公开(公告)日：2011-10-25

    申请号：US11904583

    申请日：2007-09-27

    申请人： Jan Boese ,  Matthias John ,  Norbert Rahn

    发明人： Jan Boese ,  Matthias John ,  Norbert Rahn

    IPC分类号： G06K9/00

    CPC分类号： G06T15/08 ,  G06T7/38 ,  G06T11/008 ,  G06T2207/10072

    摘要： The invention relates to a device for merging a 2D radioscopy image with an image obtained from a 3D image data record, having a memory unit that stores the 2D radioscopy image and the 3D image data record, a segmentation unit that segments an inner surface of a hollow organ from the 3D image data record, a registration unit that registers the 2D radioscopy image with the 3D image data record, a back-projection unit that back-projects the pixels of the 2D radioscopy image onto the segmented surface, taking account of the projection geometry of the 2D radioscopy image and the registration, and an image merger unit that generates a virtual endoscopy view of the surface from the segmented surface using the back-projected pixels. The device primarily allows 2D radioscopy images to be superimposed during interventional procedures with a fly display of the interior of an interesting organ.

    摘要翻译： 本发明涉及一种用于将2D放射线图像与从3D图像数据记录获得的图像合并的装置，具有存储2D放射线图像和3D图像数据记录的存储单元，分割单元，其将 来自3D图像数据记录的空心器官，将2D放射线图像与3D图像数据记录注册的登记单元，将2D放射线图像的像素反投影到分割表面上的背投影单元，考虑到 2D放射线图像的投影几何图像和配准，以及图像合并单元，其使用后投影像素从分割表面生成表面的虚拟内窥镜视图。 该装置主要允许在介入手术过程中叠加2D放射成像图像，并显示有趣器官内部的飞行显示。

    Method and apparatus for processing of diagnostic image data
    27.
    发明授权
    Method and apparatus for processing of diagnostic image data 有权
    用于处理诊断图像数据的方法和装置

    公开(公告)号：US07924280B2

    公开(公告)日：2011-04-12

    申请号：US11526803

    申请日：2006-09-26

    申请人： Matthias John

    发明人： Matthias John

    IPC分类号： G06T17/00

    CPC分类号： G06T19/00 ,  G06T7/0012 ,  G06T7/11 ,  G06T7/187 ,  G06T7/60 ,  G06T2207/10081 ,  G06T2207/10088 ,  G06T2207/30101 ,  G06T2210/41

    摘要： A method is disclosed for processing of diagnostic image data. In one embodiment, the method includes determination of three-dimensional image information using an imaging medico-technical method, in which an examined volume is subdivided into a plurality of voxels and each voxel is allocated one measurement value, and selection of a subset of the voxels, with the measurement values which are associated with the selected voxels satisfying a specific relationship with a limit value. The method further includes identification of at least one cohesive volume area within the selected subset of the voxels, determination of a surface of the identified cohesive volume area, and determination of the distance between voxels within the cohesive volume area and the surface. Additionally, the method includes identification of volume elements within the cohesive volume area, with each volume element having a central voxel whose distance from the surface represents a local maximum, determination of a constriction within the cohesive volume area, which constriction separates identified volume elements from one another, and subdivision of the determined image information into a plurality of data subsets, with the constriction providing a boundary between the different data subsets.

    摘要翻译： 公开了一种用于处理诊断图像数据的方法。 在一个实施例中，该方法包括使用成像医学技术方法来确定三维图像信息，其中检查的体积被细分为多个体素，并且每个体素被分配一个测量值，并且选择 体素，其中与所选择的体素相关联的测量值满足与极限值的特定关系。 该方法还包括识别体素的所选子集内的至少一个内聚体积区域，确定所识别的内聚体积区域的表面，以及确定内聚体积区域和表面之间的体素之间的距离。 此外，该方法包括识别内聚体积区域内的体积元素，其中每个体积元素具有中心体素，其距离表面的距离表示局部最大值，确定内聚体积区域内的收缩，该收缩将识别的体积元素与 并且将所确定的图像信息细分为多个数据子集，其中收缩部提供不同数据子集之间的边界。

    OPTOELECTRONIC DETECTOR ASSEMBLY AND METHOD OF OPERATING SAME
    28.
    发明申请
    OPTOELECTRONIC DETECTOR ASSEMBLY AND METHOD OF OPERATING SAME 有权
    光电检测器组件及其操作方法

    公开(公告)号：US20110032614A1

    公开(公告)日：2011-02-10

    申请号：US12849967

    申请日：2010-08-04

    申请人： Mirko LIEDTKE ,  Matthias John

    发明人： Mirko LIEDTKE ,  Matthias John

    IPC分类号： G01N25/02 ,  G02B21/00

    CPC分类号： G02B21/362 ,  G01J1/02 ,  G01J1/0252 ,  G02B7/008 ,  G02B21/28

    摘要： An optoelectronic detector and method of using same. In order to avoid any condensation on a surface, it has been known to heat such a surface. However, heating an optoelectronic detector will create a stronger hissing noise due to the greater dark current that is caused thereby. The invention is intended to avoid any condensation on an optoelectronic detector without airtight encapsulation. To this end, the detector is cooled and equipped with a sensor for the determination of a current value of one of the variables ambient humidity and ambient dew point temperature and a control unit that is connected with the sensor and designed to control the cooling device in dependence of such a value. By taking into account the ambient humidity or, respectively, the dew point temperature in the control of the cooling device, condensation on the detector can be avoided. An airtight encapsulation of the detector and the cooling device is not required.

    摘要翻译： 一种光电检测器及其使用方法。 为了避免表面上的任何冷凝，已知加热这种表面。 然而，由于由此引起的较大的暗电流，加热光电检测器将产生更强的嘶嘶声。 本发明旨在避免光电检测器上没有气密封装的任何冷凝。 为此，检测器被冷却并配备有用于确定环境湿度和环境露点温度之一的变量的当前值的传感器，以及与传感器连接并被设计成控制冷却装置的控制单元 这种价值的依赖。 通过考虑环境湿度或分别控制冷却装置的露点温度，可以避免检测器上的冷凝。 不需要检测器和冷却装置的气密封装。