公开(公告)号：US09118937B2

公开(公告)日：2015-08-25

申请号：US12245037

申请日：2008-10-03

Applicant: Martin Miller ,  Wen Zhang ,  David Knapp

Inventor： Martin Miller ,  Wen Zhang ,  David Knapp

IPC: H04J3/06 ,  H04N21/236 ,  H04N21/2383 ,  H04N21/242 ,  H04N21/434 ,  H04N21/647

CPC classification number: H04N21/23602 ,  H04J3/0626 ,  H04N21/2383 ,  H04N21/242 ,  H04N21/4342 ,  H04N21/647 ,  H04N21/64792

Abstract: A system for transferring real-time video data over a network comprises a video source, a video encoder for encoding and compressing video data supplied by the video source and a first network interface controller for transmitting compressed video data on the network. Furthermore a second network interface controller for receiving compressed video data from the network, a video decoder for decoding the video data received by the second network interface controller, and an image processor for processing and/or displaying the decoded video data from the video decoder are provided. The network controllers are configured for transmitting and receiving data in a continuous data stream which is synchronized with a clock signal and in a format which prescribes a pulse sequence of individual bit groups of which at least one is used for video data.

Abstract translation: 用于通过网络传送实时视频数据的系统包括视频源，用于编码和压缩由视频源提供的视频数据的视频编码器和用于在网络上发送压缩视频数据的第一网络接口控制器。 此外，用于从网络接收压缩视频数据的第二网络接口控制器，用于对由第二网络接口控制器接收的视频数据进行解码的视频解码器和用于处理和/或显示来自视频解码器的解码视频数据的图像处理器， 提供。 网络控制器被配置为在与时钟信号同步的连续数据流中发送和接收数据，并且以规定至少一个用于视频数据的各个位组的脉冲序列的格式。

公开(公告)号：US08137397B2

公开(公告)日：2012-03-20

申请号：US10787618

申请日：2004-02-26

Applicant: Fredericus A. Colen ,  David Knapp

Inventor： Fredericus A. Colen ,  David Knapp

IPC: A61F2/06

CPC classification number: A61F2/82 ,  A61F2250/0067 ,  A61F2310/0097

Abstract: Medical devices, particularly stents, suitable for drug delivery and including a sugar, sugar derivative, inorganic ionic salt, polysaccharide, amino acid, amino acid derivative, polypeptide, surfactant, or combination thereof, are disclosed.

Abstract translation: 公开了适用于药物输送并包括糖，糖衍生物，无机离子盐，多糖，氨基酸，氨基酸衍生物，多肽，表面活性剂或其组合的医疗装置，特别是支架。

公开(公告)号：US07947299B2

公开(公告)日：2011-05-24

申请号：US11598903

申请日：2006-11-14

Applicant: David Knapp

Inventor： David Knapp

IPC: A61F13/00 ,  A61F2/00

CPC classification number: A61L31/16 ,  A61K31/198 ,  A61K38/363 ,  A61K38/4833 ,  A61K45/06 ,  A61L29/16 ,  A61L2300/45 ,  A61L2300/606 ,  A61L2300/622 ,  A61K2300/00

Abstract: A therapeutic medical article is provided which comprises a medical article, a precursor compound and an activator compound. The medical article is adapted, upon administration to a patient, to release the precursor compound and the activator compound such that the activator compound interacts with the precursor compound and converts the precursor compound into activated form for local delivery. Specific examples of precursor and activator compound pairs include: (a) a nitrosothiol precursor and a nitric oxide donor, (b) plasminogen and plasminogen activator, and (c) fibrinogen and thrombin.

Abstract translation: 提供一种治疗性医疗用品，其包括医疗制品，前体化合物和活化剂化合物。 医疗制品在给予患者时适应释放前体化合物和活化剂化合物，使得活化剂化合物与前体化合物相互作用并将前体化合物转化为活化形式用于局部递送。 前体和活化剂化合物对的具体实例包括：（a）亚硝基硫醇前体和一氧化氮供体，（b）纤溶酶原和纤溶酶原激活剂，和（c）纤维蛋白原和凝血酶。

公开(公告)号：US07588780B2

公开(公告)日：2009-09-15

申请号：US10215594

申请日：2002-08-09

Applicant: Marcia Buiser ,  Marc Bellisario ,  David Knapp ,  Stephan Mangin ,  Janel Lanphere

Inventor： Marcia Buiser ,  Marc Bellisario ,  David Knapp ,  Stephan Mangin ,  Janel Lanphere

IPC: A61K9/14 ,  A61K9/50 ,  B01J13/02 ,  B32B15/02

CPC classification number: C08J3/24 ,  A61F2/0036 ,  A61K9/1635 ,  A61K49/0452 ,  A61L24/001 ,  A61L24/0036 ,  A61L24/06 ,  A61L27/16 ,  A61L27/50 ,  A61L31/048 ,  A61L2430/36 ,  C08J3/12 ,  C08J2329/04 ,  Y10T428/2985 ,  C08L29/04

Abstract: Embolic polymer particles are described. For example, the particles include pores such that the predominant size of pores near the center of the particles is greater than the predominant size of pores adjacent to periphery of the particle

Abstract translation: 描述栓塞聚合物颗粒。 例如，颗粒包括孔，使得在颗粒中心附近的孔的主要尺寸大于邻近颗粒周边的孔的主要尺寸。

公开(公告)号：US07488794B2

公开(公告)日：2009-02-10

申请号：US10881713

申请日：2004-06-30

Applicant: Robert A. Herrmann ,  David Knapp

Inventor： Robert A. Herrmann ,  David Knapp

IPC: C07K1/113 ,  C08B37/16

CPC classification number: C07C381/00 ,  C08B37/00 ,  C08B37/0012

Abstract: A method for producing a S-nitrosylated species is provided. The method comprises: (a) providing a deoxygenated, alkaline aqueous solution comprising a thiol and a nitrite-bearing species; (b) acidifying the solution by adding acid to the solution while concurrently mixing the solution (e.g., by vigorously stirring the solution) to produce the S-nitrosylated species; and (c) isolating the S-nitrosylated species. The nitrite-bearing species can be, for example, an inorganic nitrite, such as an alkali metal nitrite, or an organic nitrite, such as an alkyl nitrite (e.g., ethyl nitrite, amyl nitrite, isobutyl nitrite or t-butyl nitrite). The thiol is preferably a thiol-containing polysaccharide, a thiol-containing lipoprotein, a thiol-containing amino acid or a thiol-containing protein, and more preferably a thiol-containing polysaccharide such as thiolated cyclodextrin. In many preferred embodiments, the S-nitrosylated species is insoluble in the acidified solution, precipitating upon formation. The S-nitrosylated species can be isolated, for example, by a process in which the precipitate is removed from the solution (e.g., by centrifugation) and the aqueous solvent remaining in the precipitate is sublimated (e.g., by freezing the precipitate and subjecting it to a vacuum). The isolated S-nitrosylated product is preferably protected from heat, light, moisture and oxygen.

公开(公告)号：US20080095191A1

公开(公告)日：2008-04-24

申请号：US11961086

申请日：2007-12-20

Applicant: David Knapp ,  Patrick Heck

Inventor： David Knapp ,  Patrick Heck

IPC: H04J3/22

CPC classification number: H04J3/1682 ,  H04J3/0638 ,  H04J3/12

Abstract: A communication system, network interface, and communication port is provided for interconnecting a network of multimedia devices. The multimedia devices can send streaming and/or non-streaming data across the network. The network accommodates all such types of data and assigns data types to time slots or frame segments within each frame to ensure streaming data maintains its temporal relationship at the receiver consistent with the transmitter. A signaling byte is preferably used to keep track of an amount by which isochronous streaming data occupies a frame segment.

公开(公告)号：US20070075237A1

公开(公告)日：2007-04-05

申请号：US11243562

申请日：2005-10-05

Applicant: James Mills ,  David Garrett ,  Wayne Sunne ,  David Knapp ,  Daniel Brunton ,  David Anthony ,  Emmet Anderson ,  Daniel Harrison ,  Frank Smith ,  Jim Hicks

Inventor： James Mills ,  David Garrett ,  Wayne Sunne ,  David Knapp ,  Daniel Brunton ,  David Anthony ,  Emmet Anderson ,  Daniel Harrison ,  Frank Smith ,  Jim Hicks

IPC: H01J5/02 ,  H01J40/14

CPC classification number: F41G7/224 ,  F41H13/0056 ,  G01S7/4818 ,  G01S7/495

Abstract: A control mechanism pins an optical fiber assembly on and off gimbal and between gimbals to route the assembly from an off-gimbal optical source across the gimbal axis/axes to an on-gimbal optical element so that the fiber assembly moves with the rotation of the gimbals. To accommodate a relatively large range of motion, the control mechanism is suitably configured to route the fiber assembly in a “U-shaped” loop with one end pinned off-gimbal in a stationary guide track and the other end pinned on-gimbal point in a rotating guide track so that the loose fiber assembly is constrained in the concentric tracks on and off gimbal. As the gimbal rotates, the loop seats onto one guiding track and peels off of the other guiding track while always maintaining its U shape. To accommodate a relatively small range of motion in other gimbal configurations, the control mechanism is suitably configured to pin one end of the fiber assembly off-gimbal and pass the fiber assembly directly over the gimbal where it is pinned on the other side of the gimbal. In a multi-gimbal pointer, the fiber assembly preferably exhibits different mechanical stresses as it crosses the different gimbals.

Abstract translation: 控制机构将光纤组件插入和关闭万向节和万向节之间，以将组件从万向节光源穿过万向节轴/轴线到达万向节光学元件，使得光纤组件随着 万向节 为了适应相对较大的运动范围，控制机构被适当地构造成将光纤组件以“U形”形环路路线固定在固定导轨中，另一端固定在万向节上 旋转的导轨，使得松散的纤维集合体被限制在同步轨道上和/或从万向节关闭。 当万向架旋转时，环路将位于一个引导轨道上并从另一个引导轨道剥离，同时始终保持其U形。 为了适应其他万向架构中的相对较小的运动范围，控制机构适当地构造成将纤维组件的一端分离成万向节，并将纤维组件直接通过万向节，将其固定在万向节的另一侧 。 在多万向节指针中，纤维组件优选地在穿过不同的万向节时表现出不同的机械应力。

公开(公告)号：US06904310B2

公开(公告)日：2005-06-07

申请号：US10140738

申请日：2002-05-07

Applicant: David Knapp ,  Brian T. Berg

Inventor： David Knapp ,  Brian T. Berg

IPC: A61B6/00 ,  A61B6/03 ,  A61B6/12 ,  A61F2/86 ,  A61L31/18 ,  H05G1/70

CPC classification number: A61F2/86 ,  A61B6/482 ,  A61F2/91 ,  A61L31/18

Abstract: A method for obtaining diagnostic information about a region of a living being, the region having a medical device with a radiopaque portion disposed therein. An X-ray beam having a first energy level in excess of the K-absorption edge of the radiopaque portion of the medical device is directed at the region to obtain a first image information and radiographically locate the medical device within the living being and an X-ray beam having second energy level at or below the K-absorption edge is applied to the region to obtain a second image information.

公开(公告)号：US20050053179A1

公开(公告)日：2005-03-10

申请号：US10655265

申请日：2003-09-04

Applicant: David Knapp ,  Jason Lewis

Inventor： David Knapp ,  Jason Lewis

IPC: H04L7/00

CPC classification number: H04L7/0004

Abstract: A communication system, clock recovery circuit, and method are provided for allowing data to be transmitted across a communication system and between clock recovery circuits absent a clock master specifically designed for one node of the communication system. Absent a clock master, the communication system is permitted to enter into an all slave mode, with periodic unlock conditions possibly rotating about the communication system ring topology. However, the unlock condition can be readily detected and if the received data bitstream formed into a recovered clock exceeds a threshold above or is less than a threshold below a reference clock generated during instances of unlock, then the clock recovery circuit will fix the synchronizing clock to the reference clock, and cause the bitstream to resynchronize to the reference clock before the reference clock is again disabled to allow the communication system to re-enter the all slave and rotating unlock condition. Periodic application of a reference clock interspersed with periodic application of a clock having transitions equal to the incoming bitstream proves advantageous in avoiding a design where a dedicated master must be used within a specified communication system node.

Abstract translation: 提供一种通信系统，时钟恢复电路和方法，用于允许数据通过通信系统传输，并且在时钟恢复电路之间，而不存在专门为通信系统的一个节点设计的时钟主机。 没有时钟主机，通信系统被允许进入全从机模式，周期性解锁条件可能围绕通信系统环形拓扑旋转。 然而，可以容易地检测到解锁状态，并且如果形成为恢复时钟的接收数据比特流超过了在解锁实例期间产生的参考时钟以下或低于阈值以下的阈值，则时钟恢复电路将固定同步时钟 并且在再次禁用参考时钟之前使比特流重新同步到参考时钟，以允许通信系统重新进入所有从动和旋转解锁状态。 周期性地施加散布有周期性应用具有等于进入比特流的转换的时钟的参考时钟证明有利于避免必须在指定的通信系统节点内使用专用主机的设计。

公开(公告)号：US20050030644A1

公开(公告)日：2005-02-10

申请号：US10633811

申请日：2003-08-04

Applicant: David Knapp

Inventor： David Knapp

IPC: G02B13/06 ,  G02B27/00 ,  G02B17/00

CPC classification number: G02B27/4216 ,  G02B13/06 ,  G02B27/0037 ,  G02B27/0068

Abstract: An optical system includes a window having a nonspherically curved outer surface and a curved inner surface, and a transmission optical corrector adjacent to the curved inner surface of the window. The transmission optical corrector has a selectively nonuniform passive transmission optical property, such as a spatially varying index of refraction of the transmission optical corrector or a spatially varying diffractive property of the transmission optical corrector. The optical system further has an optical train positioned such that the transmission optical corrector lies between the curved window and the optical train. A sensor is disposed to receive the optical ray passing sequentially through the window, the transmission optical corrector, and the optical train.

Abstract translation: 光学系统包括具有非曲面外表面和弯曲内表面的窗口，以及与窗口的弯曲内表面相邻的透射光学校正器。 透射光学校正器具有选择性地不均匀的无源透射光学特性，例如透射光学校正器的空间变化的折射率或透射光学校正器的空间变化的衍射特性。 该光学系统还具有光学系列，该光学系列定位成使得透射光学校正器位于弯曲窗口和光学系列之间。 传感器设置成接收依次通过窗口，透射光学校正器和光学列车的光线。