公开(公告)号：US20080234629A1

公开(公告)日：2008-09-25

申请号：US12052952

申请日：2008-03-21

申请人： John Petersen

发明人： John Petersen

IPC分类号： A61N1/30

CPC分类号： A61N1/0436 ,  A61N1/0448

摘要： The present invention is an iontophoretic system that electrolyzes water to enhance the iontophoretic delivery of an active agent. The invention provides a cartridge adapted for use in iontophoretic system comprising electronics associated with a working electrode capable of electrolyzing water and a conductive composition comprising water and at least one active agent wherein the conductive composition has an initial pH in the absence of the flow of current, wherein upon flow of current through the electrode, water is electrolyzed, and the pH of the composition is changed to a second pH thereby providing enhanced iontophoretic delivery of the active agent.

摘要翻译： 本发明是电离水以增强活性剂的离子电渗疗法的离子电渗疗法。 本发明提供了一种适用于离子电渗疗法的药筒，其包括与能够电解水的工作电极相连的电子器件和包含水和至少一种活性剂的导电组合物，其中导电组合物在不存在电流的情况下具有初始pH 其中，当电流通过电极时，水被电解，并且组合物的pH变为第二pH，从而提供活性剂的增强的离子电渗疗法。

公开(公告)号：US20070185432A1

公开(公告)日：2007-08-09

申请号：US11538249

申请日：2006-10-03

申请人： Robert Etheredge ,  Dennis Goldberg ,  Phillip Friden ,  John Petersen

发明人： Robert Etheredge ,  Dennis Goldberg ,  Phillip Friden ,  John Petersen

IPC分类号： A61N1/30

CPC分类号： A61B17/205 ,  A61M37/0015 ,  A61M2037/0061

摘要： The electrokinetic methotrexate delivery system includes at least one applicator having a multiplicity of non-conductive micro-needles carried on a non-conductive surface of the applicator. The opposite surface is formed of electrically conductive material for contact with an active electrode. The applicator includes a matrix containing a medicament, e.g., methotrexate, or a carrier therefor between the opposite surfaces. When the applicator is applied to the individual's skin with the micro-needles penetrating the skin, an electrical current is completed through the power source, the active electrode, methotrexate, or electrically conductive carrier therefor, the targeted treatment site, the individual's body, a ground electrode and the power supply, thereby electokinetically driving the medicament through the non-conductive micro-needles into the targeted treatment site.

摘要翻译： 电动氨甲蝶呤递送系统包括至少一个施用器，其具有承载在施用器的非导电表面上的多个非导电微针。 相对表面由用于与有源电极接触的导电材料形成。 施用器包括在相对表面之间包含药物，例如甲氨蝶呤或其载体的基质。 当施用器被微针穿透皮肤施加到个体的皮肤上时，通过电源，有效电极，甲氨蝶呤或导电载体，目标治疗部位，个体的身体， 接地电极和电源，从而通过非导电微针将药物电动驱动到目标治疗部位。

公开(公告)号：US20110282789A1

公开(公告)日：2011-11-17

申请号：US13138286

申请日：2010-01-28

申请人： Pat Carroll ,  John Petersen ,  Jonathan Alford

发明人： Pat Carroll ,  John Petersen ,  Jonathan Alford

IPC分类号： G06Q40/00

CPC分类号： G06Q20/18 ,  G06Q20/20 ,  G06Q20/32 ,  G06Q20/322 ,  G06Q20/3224 ,  G06Q20/40 ,  H04L63/08 ,  H04L63/107 ,  H04L63/18 ,  H04W4/021 ,  H04W4/029 ,  H04W12/00503 ,  H04W12/04031 ,  H04W12/06 ,  H04W12/1206

摘要： A method for authenticating a transaction is disclosed. The method comprises the steps of: receiving data identifying a region where a transaction is being requested; receiving data identifying a mobile communication device associated with a person requesting the transaction; determining from Location Register (LR) data for the mobile communication device data identifying a region where the mobile communication device is located; comparing the data identifying the region where the transaction is being requested with the data identifying the region where the mobile communication device is located; and authenticating the transaction in dependence on the result of the comparison.

摘要翻译： 公开了一种认证交易的方法。 该方法包括以下步骤：接收标识正在请求交易的区域的数据; 接收识别与请求所述交易的人相关联的移动通信设备的数据; 从用于识别移动通信设备所在的区域的移动通信设备数据的位置寄存器（LR）数据确定; 将识别正在请求的事务的区域的数据与识别移动通信设备所在的区域的数据进行比较; 并根据比较结果对交易进行认证。

公开(公告)号：US20080051692A1

公开(公告)日：2008-02-28

申请号：US11565335

申请日：2006-11-30

申请人： John Petersen ,  Dennis Goldberg ,  James Kelland ,  Robert Ehteredge ,  Michael Barsness ,  Kuowei Chang

发明人： John Petersen ,  Dennis Goldberg ,  James Kelland ,  Robert Ehteredge ,  Michael Barsness ,  Kuowei Chang

IPC分类号： A61N1/30

CPC分类号： A61N1/303

摘要： An applicator for a device for electrokinetic delivery of medicament to a treatment site includes an applicator head having an active electrode, a matrix, and a medicament or a medicament and an electrically conductive carrier, carried by the matrix in electrical contact with the electrode. The cartridge includes a plurality of raised projections allowing the matrix and head to be ultrasonically welded one to the other. The electrode opens through a face of the head remote from the matrix for connection with an electrical connector carried by the device. A lid overlies the matrix and is releasably attached to a margin of the head. The lid includes layers of different materials with one of the layers formed of a metallic material having a discontinued interface with the lid and a tab carried by the lid.

摘要翻译： 用于将药物电动递送到治疗部位的装置的施加器包括具有活性电极，基质以及由电极与电极电接触的基质携带的药物或药物和导电载体的施用器头。 盒包括多个凸起突起，允许矩阵和头被彼此超声波焊接。 电极通过远离矩阵的头部的面打开，以与由该装置承载的电连接器连接。 盖子覆盖在基体上并且可释放地附接到头部的边缘。 盖子包括不同材料的层，其中一个层由金属材料形成，该金属材料具有与盖子不连续的界面和由盖子承载的翼片。

公开(公告)号：US20070190021A1

公开(公告)日：2007-08-16

申请号：US11498309

申请日：2006-08-01

申请人： Stephen Holmes-Farley ,  Pradeep Dhal ,  John Petersen

发明人： Stephen Holmes-Farley ,  Pradeep Dhal ,  John Petersen

IPC分类号： A61K31/787

CPC分类号： B82Y5/00 ,  A61K31/785 ,  A61K31/787 ,  A61K31/795 ,  A61K47/6949 ,  C08G61/12 ,  Y10S514/824

摘要： The present invention relates to a method for removing bile acids from a patient and certain polymers of use in the method. The method comprises the step of administering to the patient a therapeutically effective amount of a polymer composition which includes a a poly(diallylamine)polymer which is substituted with hydrophobic groups. The hydrophobic groups can be a substituted or unsubstituted, straight chain or branched C3-C24-alkyl group, an aralkyl group or an aryl group.

摘要翻译： 本发明涉及一种从患者中除去胆汁酸的方法和本方法中使用的某些聚合物。 该方法包括向患者施用治疗有效量的聚合物组合物的步骤，该聚合物组合物包括被疏水基团取代的聚（二烯丙基胺）聚合物。 疏水基团可以是取代或未取代的直链或支链C 3 -C 24 - 烷基，芳烷基或芳基。

公开(公告)号：US5697527A

公开(公告)日：1997-12-16

申请号：US681320

申请日：1996-07-22

申请人： Anthony Altieri, Jr. ,  John Lewis Fortin ,  Richard David Bothmann ,  Sandra Jean Liakus ,  Philip DiGangi ,  Dietrich M.E. Heyde ,  John Petersen ,  James M. Mayer ,  Errol Olsen ,  Robert Stewart, deceased

发明人： Anthony Altieri, Jr. ,  John Lewis Fortin ,  Richard David Bothmann ,  Sandra Jean Liakus ,  Philip DiGangi ,  Dietrich M.E. Heyde ,  John Petersen ,  James M. Mayer ,  Errol Olsen ,  Robert Stewart, deceased

IPC分类号： B67D99/00 ,  B01F13/10 ,  B67D7/02 ,  B67D7/62 ,  B67D7/78 ,  F04C2/08 ,  B67D5/20

CPC分类号： B67D7/02 ,  B01F13/1055 ,  B67D7/62 ,  B67D7/78 ,  F04C2/082 ,  F05C2251/10

摘要： A machine for dispensing a plurality of ingredients includes stepped arrays of canisters providing a source of materials. The bottom ends of the canisters are generally coplanar, and are positioned immediately above a low profile drive train mounted on a tray. A drive train includes two spaced arrays of pumps with a motor providing a common drive for the pumps, mounted between the arrays. A valve tray is located above the canisters and includes a low profile dispense head, an array of tubing members arranged side-by-side in a common, generally horizontal plane, and an array of dispense valves attached at the back of the valve tray. The dispense valves are coupled to the pumps by pairs of fluid lines, so as to circulate materials between the pumps and dispense valves.

摘要翻译： 用于分配多种成分的机器包括提供材料来源的步骤排列的罐。 罐的底端通常是共面的，并且被定位在安装在托盘上的低轮廓传动系的正上方。 传动系列包括两个间隔开的泵阵列，电机为泵安装在阵列之间，为泵提供通用驱动。 阀盘位于罐的上方，并且包括一个低轮廓的分配头，一个并排设置在公用的大致水平的平面中的一组管件，以及一个安装在阀盘背面的分配阀阵列。 分配阀通过成对的流体管线耦合到泵，以便在泵和分配阀之间循环材料。

公开(公告)号：US5173213A

公开(公告)日：1992-12-22

申请号：US790196

申请日：1991-11-08

申请人： Richard F. Miller ,  John Petersen

发明人： Richard F. Miller ,  John Petersen

IPC分类号： C10G70/04 ,  C23F11/14

CPC分类号： C23F11/14 ,  C10G70/048

摘要： The corrosion and fouling of metal surfaces in contact with corrosive acid fluids or acid salts in the presence of an aqueous medium is reduced by contacting the surfaces with a composition which comprises (a) an anti-fouling amount of a hydroxyl amine compound of the formulaR.sub.1 R.sub.2 N--OHwherein R.sub.1 and R.sub.2 are independently hydrogen or a hydrocarbyl or inertly substituted hydrocarbyl or both R.sub.1 and R.sub.2 are collectively a divalent hydrocarbyl combined with said nitrogen to form a heterocyclic ring, and (b) a corrosion-inhibiting amount of a reaction product of or a mixture for the purpose of a reaction product of a polyalkylene polyamine and an alkynediol. The polyalkylene polyamine is one that contains from 2-10 amine groups, each separated from another by an alkylene group having from 2-6 carbon atoms. The alkynediol has from 2 to 6 carbon atoms.

摘要翻译： 在水性介质存在下，与腐蚀性酸性流体或酸式盐接触的金属表面的腐蚀和结垢通过使表面与包含（a）抗结垢量的式 R1R2N-OH其中R1和R2独立地是氢或烃基或惰性取代的烃基，或者R1和R2两者一起是与所述氮组合形成杂环的二价烃基，和（b）腐蚀抑制量的反应产物 的聚亚烷基多胺和炔二醇的反应产物的混合物。 聚亚烷基多胺是含有2-10个胺基的聚亚烷基多胺，各自由具有2-6个碳原子的亚烷基彼此分开。 炔二醇具有2至6个碳原子。

公开(公告)号：US20140201615A1

公开(公告)日：2014-07-17

申请号：US11444023

申请日：2006-05-31

申请人： N. Isaac Rajkumar ,  Mark McCalister ,  Expeditus Bolanos ,  Peter Hale ,  Mark Martin ,  Richard Nemec ,  Puhong You ,  Daun DeFrance ,  Ching-Fu Chang ,  Priya Reddy ,  Ladislav Kis ,  Robert L. Patterson ,  Tony Zgarba ,  Jeffrey M. Collins ,  Michael C. Tulkoff ,  Miles Chaston ,  John Petersen ,  Ian Stahl ,  Lara Long

发明人： N. Isaac Rajkumar ,  Mark McCalister ,  Expeditus Bolanos ,  Peter Hale ,  Mark Martin ,  Richard Nemec ,  Puhong You ,  Daun DeFrance ,  Ching-Fu Chang ,  Priya Reddy ,  Ladislav Kis ,  Robert L. Patterson ,  Tony Zgarba ,  Jeffrey M. Collins ,  Michael C. Tulkoff ,  Miles Chaston ,  Dean Moses ,  John Petersen ,  Ian Stahl ,  Lara Long

IPC分类号： G06F17/22

CPC分类号： G06F17/30893 ,  G06F17/30011 ,  G06F17/3089 ,  G06F17/30902 ,  H04L67/02

摘要： Disclosed herein are embodiments of a system and method for the dynamic provisioning of static content. In one embodiment, information presented on a content delivery system can be refreshed based on information published on a content management system. One embodiment can interface the content delivery system and the content management system at the page level. More specifically, content dependencies across pages employing the same content or portion(s) thereof can be tracked in a timely, accurate manner. Upon receiving a notification of a change to the content or a portion thereof from the content management system, a content generation system may operate to determine, based on the dependencies, what pages are affected by the change and, based on the determination, dynamically regenerate any and all affected pages. The regenerated pages may then be stored and/or pushed to the web tier for delivery to end users.

公开(公告)号：US20140172712A1

公开(公告)日：2014-06-19

申请号：US14124257

申请日：2012-06-07

申请人： John Petersen ,  Pat Carroll ,  Jon Alfrod

发明人： John Petersen ,  Pat Carroll ,  Jon Alfrod

IPC分类号： G06Q20/40

CPC分类号： G06Q20/4016 ,  G06Q10/00 ,  G06Q20/00

摘要： A method for authorising a remote transaction comprises receiving a request to complete a remote transaction from a remote user, for example over the Internet. A telephone number of a telephone, in particular a mobile telephone, associated with the remote user is identified in a database. A subscriber identity associated with the telephone number is requested from a telephone network operator associated with the identified telephone number. The subscriber identity received from the network operator is compared with a stored subscriber identity associated with the remote user. If the received subscriber identity matches the stored subscriber identity authentication information is communicated with the remote user via the telephone. If the received subscriber identity does not match the stored subscriber identity additional identifying information is requested from the remote user. The method has the advantage of preventing fraudulent authorisation of the transaction by a fraudster redirecting the telephone number to their own telephone.

摘要翻译： 用于授权远程事务的方法包括从远程用户（例如，通过因特网）接收完成远程事务的请求。 在数据库中识别与远程用户相关联的电话的电话号码，特别是移动电话。 从与所识别的电话号码相关联的电话网络运营商请求与电话号码相关联的订户身份。 将从网络运营商接收的订户身份与与远程用户相关联的存储的订户身份进行比较。 如果所接收的订户身份与存储的订户身份认证信息相匹配，则通过电话与远程用户通信。 如果接收到的用户标识与存储的订户身份不匹配，则从远程用户请求附加标识信息。 该方法具有防止欺诈者将电话号码重定向到他们自己的电话的交易授权欺诈的优点。

公开(公告)号：US20070144074A1

公开(公告)日：2007-06-28

申请号：US11275361

申请日：2005-12-28

申请人： John Petersen

发明人： John Petersen

IPC分类号： B24D11/00 ,  C09K3/14

CPC分类号： B24D15/04 ,  B24D11/02

摘要： A resilient hand-held abrasive article includes a flexible conformable backing layer having opposed first and second major surfaces, a flexible reinforcing layer affixed to at least one of the backing layer first and second major surfaces, and abrasive particles arranged on the reinforcing layer, thereby defining an abrasive surface. The backing layer comprises a multiplicity of separated resilient bodies connected to each other in a generally planar array in a pattern that provides open spaces between adjacent connected bodies.

摘要翻译： 弹性手持磨料制品包括具有相对的第一和第二主表面的柔性适形背衬层，固定到背衬层第一和第二主表面中的至少一个的柔性增强层，以及布置在增强层上的磨料颗粒，由此 限定研磨表面。 背衬层包括多个分离的弹性体，它们以大致平面的阵列彼此连接，其形式在相邻连接体之间提供开放空间。