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公开(公告)号：US06584335B1
公开(公告)日：2003-06-24
申请号：US09485004
申请日：2000-05-08
IPC分类号： A61B500
CPC分类号： G01N21/8507 , A61B5/14532 , A61B5/1459 , A61B5/6848 , A61B5/6849 , G02B6/241
摘要： Analysis device for determining an analyte in vivo in the body of a patient, having a measuring probe with a hollow needle (18) which can pierce through the skin. Light is passed through the hollow needle (18) and into the body via an optical fiber (22) travelling in the hollow needle (18). The light transported in the optical fiber (22) is modified in the measuring probe (3), the modification being characteristic of the presence of the analyte. A measurement and evaluation unit (4) measures the change to extract information concerning the presence of the analyte in the body. The hollow needle (18) is permeable, at least in a partial section of its length, serving as a measuring section (30) which can be inserted into the skin so that interstitial liquid may penetrate through the hollow needle wall to a measuring section of the optical fiber extending in the hollow needle (18) and the modification of the light characteristic of the presence of the analyte is effected through interaction with the interstitial liquid in the measuring section.
摘要翻译： 用于确定患者体内的分析物的分析装置，其具有带有可刺穿皮肤的空心针（18）的测量探针。 光通过中空针（18）通过在中空针（18）中行进的光纤（22）进入体内。 在光纤（22）中传输的光在测量探针（3）中被修改，该修改是分析物存在的特征。 测量和评估单元（4）测量改变以提取关于分析物在体内的存在的信息。 中空针（18）至少在其长度的局部剖面中是可渗透的，用作可插入皮肤的测量部分（30），使得间隙液可以穿过中空针壁穿过测量部分 在中空针（18）中延伸的光纤和通过与测量部中的间隙液的相互作用来实现分析物的存在的光特性的修改。
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公开(公告)号：US09883828B2
公开(公告)日：2018-02-06
申请号：US12101971
申请日：2008-04-12
申请人： Hans-Peter Haar , Hans List
发明人： Hans-Peter Haar , Hans List
CPC分类号： A61B5/157 , A61B5/14532 , A61B5/1459 , A61B5/150022 , A61B5/150419 , A61B5/150435 , A61B5/150511 , A61B5/150519 , A61B5/15107 , A61B5/15115 , A61B5/15151 , A61B5/15163 , A61B5/15174 , A61B5/6848 , G01N21/7703 , G01N2021/7773
摘要： The invention relates to a test element as a single-use article for examining a body fluid, comprising a lancing member that can be inserted into a body part, a collecting area configured thereon for body fluid obtained by the lancing and at least one light guide for an optical measurement in the collecting area. The collecting area is formed by a collection recess of the lancing member which extends in the lancing direction and the light guide is integrated into the lancing member such that it is secure against displacement and the distal end thereof is arranged in a proximal measurement zone of the collection recess.
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公开(公告)号：US09289162B2
公开(公告)日：2016-03-22
申请号：US13365404
申请日：2012-02-03
申请人： Hans-Juergen Kuhr , Herbert Harttig , Hans-Peter Haar , Hans List
发明人： Hans-Juergen Kuhr , Herbert Harttig , Hans-Peter Haar , Hans List
CPC分类号： A61B5/1411 , A61B5/14532 , A61B5/1459 , A61B5/150022 , A61B5/150175 , A61B5/150419 , A61B5/150435 , A61B5/150503 , A61B5/150946 , A61B5/15117 , A61B5/15123 , A61B5/15128 , A61B5/1513 , A61B5/15132 , A61B5/15186 , A61B5/1519 , A61B5/15194 , A61B5/157
摘要： The invention concerns a control device for a medical test system which has a lancing element that can be inserted into body tissue to collect body fluid and a lancing drive for the lancing element. A sensor element for body fluid is arranged on the lancing element and a control unit is coupled to the sensor element for detecting a fault when collecting body fluid. In order to improve the success rate, the control unit actuates the lancing drive for an automatic puncture repetition in less than 1 second when a fault, e.g., inadequate wetting of a detection field, occurs.
摘要翻译： 本发明涉及用于医疗测试系统的控制装置，其具有可以插入身体组织以收集体液的穿刺元件和用于穿刺元件的穿刺驱动器。 用于体液的传感器元件布置在穿刺元件上，并且控制单元联接到传感器元件，用于在收集体液时检测故障。 为了提高成功率，当出现故障（例如，检测场的不充分）时，控制单元在小于1秒钟内启动穿刺驱动以进行自动穿刺重复。
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24.发明申请DETECTING THE DECOMPOSITION OF ENZYMES IN A TEST ELEMENT BY MEANS OF CONTROLLED RELEASE OF A PROTECTED ANALYTE 审中-公开通过受保护分析仪的控制释放检测测试单元中酶的分解公开(公告)号：US20130052674A1
公开(公告)日：2013-02-28
申请号：US13524199
申请日：2012-06-15
申请人： Carina Horn , Dieter Heindl , Hans-Peter Haar , Nelli Steinke
发明人： Carina Horn , Dieter Heindl , Hans-Peter Haar , Nelli Steinke
CPC分类号： C12Q1/54
摘要： In one form, a diagnostic element for determining at least one analyte is provided. In a further form, an analytical measuring device includes the diagnostic element. Still, other forms are related to methods for the determination of an analyte, correcting a signal generated by an analyte, and/or checking the detection optics of an analytical measuring device using the diagnostic element. Another form is related to a system for the controlled release of a reagent and the use of such a system as a circuit element. Other aspects include, but are not limited to, unique methods, techniques, products, systems and devices involving diagnostic elements.
摘要翻译： 在一种形式中，提供了用于确定至少一种分析物的诊断元件。 在另一种形式中，分析测量装置包括诊断元件。 仍然，其它形式涉及用于确定分析物的方法，校正由分析物产生的信号和/或使用诊断元件检查分析测量装置的检测光学元件。 另一种形式涉及用于控制释放试剂的系统以及使用诸如电路元件的系统。 其他方面包括但不限于涉及诊断元件的独特方法，技术，产品，系统和设备。
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公开(公告)号：US20120281219A1
公开(公告)日：2012-11-08
申请号：US13466834
申请日：2012-05-08
申请人： Herbert Harttig , Hans-Peter Haar , Gerhard Werner
发明人： Herbert Harttig , Hans-Peter Haar , Gerhard Werner
IPC分类号： G01N21/84
CPC分类号： G01N21/314 , G01N21/8483
摘要： Methods and devices for analyzing body fluids, in particular for determining blood glucose. Body fluid is applied to a test element for single-use in a test device and the test element is optically coupled to a photometric measuring unit by means of an optical transmission system, wherein a time course of measuring values is recorded after the body fluid has been applied in order to detect a component of the body fluid on the test element. The transmission behavior of the optical transmission system may be controlled by recording measuring values at two different measurement wavelengths.
摘要翻译： 用于分析体液的方法和装置，特别是用于测定血糖。 体液被施加到用于测试装置中的单次使用的测试元件，并且测试元件通过光学传输系统光学耦合到光度测量单元，其中在体液具有后记录测量值的时间过程 被应用以检测测试元件上的体液的一部分。 可以通过在两个不同的测量波长处记录测量值来控制光传输系统的传输行为。
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26.发明申请公开(公告)号：US20120043377A1
公开(公告)日：2012-02-23
申请号：US13021382
申请日：2011-02-04
CPC分类号： A61B5/14546 , A61B5/14532 , A61B5/1455 , A61B90/90 , A61B90/94 , A61B90/96 , A61B90/98 , A61B2562/0295 , A61B2562/08
摘要： A medical system is proposed comprising at least one medical device for carrying out at least one medical function, and at least one medical consumable item interacting with the medical device in order to carry out the medical function. The medical device has at least one code reader for reading out at least one information component of an optical code on the medical consumable item. The code reader has at least one image sensor having a plurality of sensors. Furthermore, the code reader comprises at least one light-optical fiber plate, which is arranged in order to guide an image of the optical code to the image sensor.
摘要翻译： 提出了一种医疗系统，其包括用于执行至少一个医疗功能的至少一个医疗装置，以及与医疗装置相互作用以执行医疗功能的至少一个医疗消耗品。 该医疗设备具有至少一个代码读取器，用于读取医疗用消耗品上的光学代码的至少一个信息分量。 代码阅读器具有至少一个具有多个传感器的图像传感器。 此外，代码阅读器包括至少一个光 - 光纤板，其布置成将光学代码的图像引导到图像传感器。
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公开(公告)号：US07889329B2
公开(公告)日：2011-02-15
申请号：US12247393
申请日：2008-10-08
CPC分类号： G06T7/0012 , G01N21/8483 , G06T7/41 , G06T2207/10056 , G06T2207/30024
摘要： A system for determining the concentration of an analyte in a liquid sample comprising a detection unit for detecting light intensities which are radiated from subareas of a detection area of a test element as well as an evaluation unit which determines a frequency distribution for the detected light intensities wherein the frequency distribution has at least one first maximum caused by unwetted subareas or at least one reference area and a second maximum caused by wetted subareas and selects at least one light intensity on the basis of the frequency distribution and determines the concentration of the analyte from the at least one selected light intensity.
摘要翻译： 一种用于确定液体样品中分析物的浓度的系统，包括用于检测从测试元件的检测区域的分区辐射的光强度的检测单元以及确定检测光强度的频率分布的评估单元 其中所述频率分布具有至少一个第一最大值，所述第一最大值是由未分区的子区域或由至少一个参考区域引起的第二最大值，以及由受潮子区域引起的第二最大值，并且基于频率分布选择至少一个光强度，并且确定分析物的浓度 所述至少一个选择的光强度。
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公开(公告)号：US07771367B2
公开(公告)日：2010-08-10
申请号：US11779070
申请日：2007-07-17
申请人： Hans-Peter Haar , Hans-Juergen Kuhr , Ortrud Quarder , Joachim Hoenes , Dirk Voelkel , Volker Zimmer
发明人： Hans-Peter Haar , Hans-Juergen Kuhr , Ortrud Quarder , Joachim Hoenes , Dirk Voelkel , Volker Zimmer
IPC分类号： A61B5/157
CPC分类号： A61B5/15163 , A61B5/14532 , A61B5/150022 , A61B5/150358 , A61B5/150412 , A61B5/150503 , A61B5/150526 , A61B5/15113 , A61B5/15117 , A61B5/15153 , A61B2562/0295
摘要： A system for analyzing a bodily fluid is described, which contains at least one lancing element, such as a lancet, stored in a first magazine, and at least one test element with a detection area, stored in a second magazine, the detection area containing reagents if necessary for use in detecting the analyte. The system also includes a housing, which encloses at least part of the first magazine and the second magazine and includes an opening for placement of a body part. At least one of the lancing elements and at least one of the test elements are located below the opening, and one of the magazines is located at least partly between the opening and the other magazine. The two magazines may at least partially overlap. The lancing element and the test element may be moved toward the opening so the body part resting on the opening can be lanced with the lancing element and the emerging bodily fluid can be collected using the test element at the same opening.
摘要翻译： 描述了一种用于分析体液的系统，其包含存储在第一仓中的至少一个穿刺元件，例如刺血针，以及存储在第二仓中的至少一个具有检测区域的测试元件，所述检测区域包含 必要时用于检测分析物的试剂。 该系统还包括壳体，该壳体包围第一仓库和第二仓库的至少一部分，并且包括用于放置身体部分的开口。 至少一个穿刺元件和至少一个测试元件位于开口下方，并且一个杂志至少部分地位于开口和另一个盒之间。 两本杂志可能至少部分重叠。 穿刺元件和测试元件可以朝着开口移动，使得搁置在开口上的身体部分可以与穿刺元件一起使用，并且可以使用同一开口处的测试元件来收集出现的体液。
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公开(公告)号：US20100168617A1
公开(公告)日：2010-07-01
申请号：US12705680
申请日：2010-02-15
申请人： Otto Fuerst , Hans-Peter Haar
发明人： Otto Fuerst , Hans-Peter Haar
IPC分类号： A61B5/151
CPC分类号： A61B5/1411 , A61B5/14532 , A61B5/1455 , A61B5/1468 , A61B5/150022 , A61B5/150282 , A61B5/150419 , A61B5/150427 , A61B5/150435 , A61B5/150519 , A61B5/150755 , A61B5/15115 , A61B5/15142 , A61B5/15153 , A61B5/157 , A61B5/411
摘要： The invention concerns a disposable diagnostic part comprising a lancing element (14) which is designed for puncturing the skin (26) and has a collecting channel (16) for taking up body fluid, and comprising a detection element (18) which has a test layer (42) provided with reagents for the detection of an analyte in the body fluid and is disposed in the collecting channel (16). In order to ensure an improved stability and biocompatibility it is proposed that the detection element (18) is provided with a sealing layer (20) that is applied to the test layer (42) and covers the reagents.
摘要翻译： 本发明涉及一次性诊断部件，其包括设计成用于穿刺皮肤（26）并具有用于吸收体液的收集通道（16）的穿刺元件（14），并且包括检测元件（18），其具有测试 层（42）设置有用于检测体液中的分析物的试剂，并且设置在收集通道（16）中。 为了确保改进的稳定性和生物相容性，建议检测元件（18）设置有施加到测试层（42）并覆盖试剂的密封层（20）。
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公开(公告)号：US20100092338A1
公开(公告)日：2010-04-15
申请号：US12622595
申请日：2009-11-20
CPC分类号： A61B5/15176 , A61B5/14532 , A61B5/1455 , A61B5/150022 , A61B5/150358 , A61B5/150419 , A61B5/150503 , A61B5/15113 , A61B5/15146 , A61B5/15151 , A61B5/15161 , A61B2562/242
摘要： A test element magazine for a system for measuring the concentration of at least one constituent in a fluid sample is provided. The test element magazine comprises at least one test element in at least one chamber. The chamber is individually sealed by a sealing element. The test element comprises at least one active portion for contacting a skin portion of a patient and/or for contacting a fluid sample, wherein the test element further comprises at least one support body, wherein the support body is adapted for being engaged by an actuator. By a forward movement of the test element the support body of the test element applies a force to the sealing element, thereby forcing open the sealing of the chamber.
摘要翻译： 提供了一种用于测量流体样品中至少一种成分的浓度的系统的测试元件盒。 测试元件盒包括至少一个室中的至少一个测试元件。 室由密封元件单独密封。 测试元件包括用于接触患者的皮肤部分和/或用于接触流体样本的至少一个活动部分，其中所述测试元件还包括至少一个支撑体，其中所述支撑体适于由致动器 。 通过测试元件的向前运动，测试元件的支撑体向密封元件施加力，从而强制打开腔室的密封。
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