公开(公告)号：US08213566B2

公开(公告)日：2012-07-03

申请号：US13000371

申请日：2009-06-22

申请人： Ewald Roessl ,  Roland Proksa ,  Jens-Peter Schlomka

发明人： Ewald Roessl ,  Roland Proksa ,  Jens-Peter Schlomka

IPC分类号： A61B6/00 ,  G06K9/00

CPC分类号： G01N23/087 ,  A61B5/4869 ,  A61B6/032 ,  A61B6/4241 ,  A61B6/481 ,  A61B6/482

摘要： An imaging system including a radiation source (110) that emits poly-chromatic radiation that traverses an examination region and a detector (116) that detects radiation traversing the examination region and produces a signal indicative of the energy of a detected photon. The system further includes an energy discriminator (122) that energy resolves the signal based on a plurality of different energy thresholds, wherein at least two of the energy thresholds have values corresponding to at least two different K-edge energies of two different elements in a mixture disposed in the examination region. The system also includes a signal decomposer (132) that decomposes the energy-resolved signal into at least a multi K-edge component representing the at least two different K-edge energies. In one instance, a stoichiometric ratio of the two different elements in the contrast agent is known and substantially constant.

摘要翻译： 一种成像系统，包括发射穿过检查区域的多色辐射的辐射源（110）和检测穿过检查区域的辐射的检测器（116），并产生指示检测到的光子的能量的信号。 所述系统还包括能量鉴别器（122），所述能量鉴别器（122）能量基于多个不同的能量阈值来解析所述信号，其中所述能量阈值中的至少两个具有对应于两个不同元素的至少两个不同K边能量的值 混合物置于检查区域。 该系统还包括信号分解器（132），其将能量分辨信号分解成代表至少两个不同的K边缘能量的至少多个K边缘分量。 在一种情况下，造影剂中两种不同元素的化学计量比是已知的并且基本上是恒定的。

公开(公告)号：US20110096905A1

公开(公告)日：2011-04-28

申请号：US13000371

申请日：2009-06-22

申请人： Ewald Roessl ,  Roland Proksa ,  Jens-Peter Schlomka

发明人： Ewald Roessl ,  Roland Proksa ,  Jens-Peter Schlomka

IPC分类号： G01N23/04

CPC分类号： G01N23/087 ,  A61B5/4869 ,  A61B6/032 ,  A61B6/4241 ,  A61B6/481 ,  A61B6/482

摘要： An imaging system including a radiation source (110) that emits poly-chromatic radiation that traverses an examination region and a detector (116) that detects radiation traversing the examination region and produces a signal indicative of the energy of a detected photon. The system further includes an energy discriminator (122) that energy resolves the signal based on a plurality of different energy thresholds, wherein at least two of the energy thresholds have values corresponding to at least two different K-edge energies of two different elements in a mixture disposed in the examination region. The system also includes a signal decomposer (132) that decomposes the energy-resolved signal into at least a multi K-edge component representing the at least two different K-edge energies. In one instance, a stoichiometric ratio of the two different elements in the contrast agent is known and substantially constant.

摘要翻译： 一种成像系统，包括发射穿过检查区域的多色辐射的辐射源（110）和检测穿过检查区域的辐射的检测器（116），并产生指示检测到的光子的能量的信号。 所述系统还包括能量鉴别器（122），所述能量鉴别器（122）能量基于多个不同的能量阈值来解析所述信号，其中所述能量阈值中的至少两个具有对应于两个不同元素的至少两个不同K边能量的值 混合物置于检查区域。 该系统还包括信号分解器（132），其将能量分辨信号分解成代表至少两个不同的K边缘能量的至少多个K边缘分量。 在一种情况下，造影剂中两种不同元素的化学计量比是已知的并且基本上是恒定的。

公开(公告)号：US20110012014A1

公开(公告)日：2011-01-20

申请号：US12934661

申请日：2009-03-20

申请人： Amir Livne ,  Naor Wainer ,  Jens-Peter Schlomka ,  Ewald Roessl ,  Roland Proksa

发明人： Amir Livne ,  Naor Wainer ,  Jens-Peter Schlomka ,  Ewald Roessl ,  Roland Proksa

IPC分类号： G01D18/00

CPC分类号： G01T7/005 ,  A61B6/032 ,  A61B6/4035 ,  A61B6/4042 ,  A61B6/4441 ,  A61B6/482 ,  A61B6/585 ,  G01N2223/3037 ,  G01T1/1647

摘要： A method includes detecting radiation that traverses a material having a known spectral characteristic with a radiation sensitive detector pixel that outputs a signal indicative of the detected radiation and determining a mapping between the output signal and the spectral characteristic. The method further includes determining an energy of a photon detected by the radiation sensitive detector pixel based on a corresponding output of the radiation sensitive detector pixel and the mapping.

摘要翻译： 一种方法包括利用辐射敏感检测器像素检测穿过具有已知光谱特性的材料的辐射，所述辐射敏感检测器像素输出指示检测到的辐射的信号并确定输出信号和光谱特性之间的映射。 该方法还包括基于辐射敏感检测器像素的对应输出和映射来确定由辐射敏感检测器像素检测到的光子的能量。

公开(公告)号：US09269471B2

公开(公告)日：2016-02-23

申请号：US13260380

申请日：2010-03-15

申请人： Ewald Roessl ,  Thomas Koehler ,  Gerhard Martens

发明人： Ewald Roessl ,  Thomas Koehler ,  Gerhard Martens

IPC分类号： A61B6/03 ,  G21K7/00 ,  A61B6/00

CPC分类号： G21K7/00 ,  A61B6/4291 ,  A61B6/484 ,  A61B6/502

摘要： An X-ray differential phase-contrast imaging system has three circular gratings. The circular gratings are aligned with the optical axis of the radiation beam and a phase stepping is performed along the optical axis with the focal spot, the phase grating and/or the absorber grating. The signal measured is the phase-gradient in radial direction away from the optical axis.

摘要翻译： X射线差分相位成像系统具有三个圆形光栅。 圆形光栅与辐射束的光轴对准，并且沿着光轴与焦斑，相位光栅和/或吸收光栅一起执行相位步进。 测量的信号是远离光轴的径向相位梯度。

公开(公告)号：US20140169653A1

公开(公告)日：2014-06-19

申请号：US14236668

申请日：2012-07-27

申请人： Hanns-Ingo Maack ,  Ewald Roessl ,  Thomas Koehler ,  Roland Proska

发明人： Hanns-Ingo Maack ,  Ewald Roessl ,  Thomas Koehler ,  Roland Proska

IPC分类号： G06T11/60

CPC分类号： G06T11/60 ,  A61B6/484 ,  G06T5/50 ,  G06T2207/10116 ,  G06T2207/20056 ,  G06T2207/20221 ,  G06T2207/30004

摘要： The present invention relates to X-ray imaging technology. In phase-contrast imaging, different types of image information, e.g. absorption image information and differential phase-contrast image information, may be obtained by a single image acquisition process. Individual types of image information comprise different image properties. The present invention relates to a frequency dependent combination of different types of image information to obtain a combined image having improved properties over the individual image information and their respective image information type. Accordingly, an apparatus (56) as well as a method (100) for image processing in X-ray imaging of an object is provided comprising receiving (102) first image information of the object of a first image information type, receiving (104) second image information of the object of a second image information type,wherein the second image information type is different from the first image information type. Subsequently the first image information and the second image information is combined (106) to obtain combined image information of the object, wherein the combination of the first image information and the second image information is a frequency-dependent combination, depending on the spatial frequency of the first image information and the second image information.

摘要翻译： 本发明涉及X射线成像技术。 在相位对比成像中，不同类型的图像信息，例如， 吸收图像信息和差分相位差图像信息可以通过单个图像获取处理获得。 各种类型的图像信息包括不同的图像属性。 本发明涉及不同类型的图像信息的频率相关组合，以获得具有相对于各个图像信息及其各自的图像信息类型具有改进的特性的组合图像。 因此，提供了一种装置（56）以及用于对象的X射线成像中的图像处理的方法（100），包括接收（102）第一图像信息类型的对象的第一图像信息，接收（104） 第二图像信息类型的对象的第二图像信息，其中第二图像信息类型与第一图像信息类型不同。 随后，将第一图像信息和第二图像信息组合（106）以获得对象的组合图像信息，其中第一图像信息和第二图像信息的组合是频率相关组合，其取决于 第一图像信息和第二图像信息。

公开(公告)号：US08611489B2

公开(公告)日：2013-12-17

申请号：US13128889

申请日：2009-11-03

申请人： Ewald Roessl

发明人： Ewald Roessl

IPC分类号： A61B6/00

CPC分类号： G01T1/1647

摘要： A spectral processor (118) includes a first processing channel (120) that generates a first spectral signal derived from a detector signal, wherein the first spectral signal includes first spectral information about the detector signal, and a second processing channel (120) that generates a second spectral signal derived from the detector signal, wherein the second spectral signal includes second spectral information about the detector signal, wherein the first and second spectral signals are used to spectrally resolve the detector signal, and wherein the detector signal is indicative of detected polychromatic radiation.

摘要翻译： 光谱处理器（118）包括产生从检测器信号导出的第一光谱信号的第一处理信道（120），其中第一光谱信号包括关于检测器信号的第一光谱信息，以及产生第二光谱信号 从所述检测器信号导出的第二光谱信号，其中所述第二光谱信号包括关于所述检测器信号的第二光谱信息，其中所述第一和第二光谱信号用于对所述检测器信号进行光谱解析，并且其中所述检测器信号指示检测到的多色 辐射。

公开(公告)号：US20120243658A1

公开(公告)日：2012-09-27

申请号：US13514682

申请日：2010-12-03

申请人： Dieter Geller ,  Klaus Juergen Engel ,  Gereon Vogtmeier ,  Thomas Koehler ,  Ewald Roessl

发明人： Dieter Geller ,  Klaus Juergen Engel ,  Gereon Vogtmeier ,  Thomas Koehler ,  Ewald Roessl

IPC分类号： G01N23/04

CPC分类号： A61B6/00 ,  A61B6/4291 ,  A61B6/4441 ,  A61B6/484

摘要： X-ray devices for Phase Contrast Imaging (PCI) are often built up with the help of gratings. For large field-of-views (FOV), production cost and complexity of these gratings could increase significantly as they need to have a focused geometry. Instead of a pure PCI with a large FOV, this invention suggests to combine a traditional absorption X-ray-imaging system with large-FOV with an insertable low-cost PCI system with small-FOV, The invention supports the user to direct the PCI system with reduced FOV to a region that he regards as most interesting for performing a PCI scan thus eliminating X-ray dose exposure for scanning regions not interesting for a radiologist. The PCI scan may be generated on the basis of local tomography.

摘要翻译： 用于相位对比成像（PCI）的X射线装置通常在光栅的帮助下构建。 对于大视野（FOV）来说，这些光栅的生产成本和复杂性可能会因为需要聚焦几何而显着增加。 本发明不是采用具有大FOV的纯PCI，而是将传统的吸收X射线成像系统与大型FOV结合，并具有小FOV的可插入低成本PCI系统。本发明支持用户指导PCI 系统将FOV降低到他认为对于执行PCI扫描最有趣的区域，从而消除了用于放射科医生不感兴趣的扫描区域的X射线剂量曝光。 可以基于局部断层摄影产生PCI扫描。

公开(公告)号：US20120057676A1

公开(公告)日：2012-03-08

申请号：US13266692

申请日：2010-05-17

申请人： Thomas Koehler ,  Ewald Roessl

发明人： Thomas Koehler ,  Ewald Roessl

IPC分类号： G21K1/06

CPC分类号： G21K1/06 ,  G21K2207/005

摘要： The invention relates to gratings for X-ray differential phase-contrast imaging, a focus detector arrangement and X-ray system for generating phase-contrast images of an object and a method of phase-contrast imaging for examining an object of interest. In order to provide gratings with a high aspect ratio but low costs, a grating for X-ray differential phase-contrast imaging is proposed, comprising a first sub-grating (112), and at least a second sub- grating (114; 116; 118), wherein the sub-gratings each comprise a body structure (120) with bars (122) and gaps (124) being arranged periodically with a pitch (a), wherein the sub-gratings (112; 114; 116; 118) are arranged consecutively in the direction of the X-ray beam, and wherein the sub-gratings (112; 114; 116; 118) are positioned displaced to each other perpendicularly to the X-ray beam.

摘要翻译： 本发明涉及用于X射线差分相位对比成像的光栅，用于产生对象的相位对比图像的焦点检测器布置和X射线系统以及用于检查感兴趣对象的相位对比成像方法。 为了提供具有高纵横比但成本较低的光栅，提出了一种用于X射线差分相位对比成像的光栅，包括第一子光栅（112）和至少第二子光栅（114; 116 ; 118），其中所述子光栅各自包括具有杆（122）和间隙（124）的主体结构（120），所述杆具有间距（a）周期性地布置，其中所述子光栅（112; 114; 116; 118 ）沿X射线束的方向连续布置，并且其中子光栅（112; 114; 116; 118）被定位成垂直于X射线束彼此位移。

公开(公告)号：US09168013B2

公开(公告)日：2015-10-27

申请号：US13991923

申请日：2011-12-08

申请人： Ewald Roessl ,  Hanns-Ingo Maack ,  Klaus Erhard

发明人： Ewald Roessl ,  Hanns-Ingo Maack ,  Klaus Erhard

IPC分类号： A61B6/00

CPC分类号： A61B6/502 ,  A61B6/00 ,  A61B6/482 ,  A61B6/488 ,  A61B6/542

摘要： The present invention relates to mammography. To provide breast density assessment with improved accuracy in the results, a method (100) is proposed for providing mammography information about an object of interest, the region of interest comprising a tissue structure, with the following steps: a) acquiring (110) first image data (112) with first image acquisition parameters (114), wherein the first image parameters are adapted to a first radiation spectrum of a dual energy mode; and wherein the first image acquisition is performed with a low X-ray dosage of a pre-scan; b) acquiring (116) second image data (118) with second image acquisition parameters (120), wherein the second image parameters are adapted to a second radiation spectrum of the dual energy mode, and wherein the second image acquisition is performed with a higher X-ray dosage than the first image acquisition, and wherein the second image acquisition is a Mammography scan; c) performing (122) a dual energy basis material decomposition (124) based on the first and second image data to generate decomposed basis material image data (126); and d) deriving (128) a density information (130) of the tissue structure of the region of interest from the decomposed basis material image data; and providing (132) the density information to a user.

摘要翻译： 本发明涉及乳房X线照相术。 为了提供结果的准确性提高乳房密度评估，提出了一种方法（100），用于提供关于感兴趣对象的乳房X射线摄影信息，所述感兴趣区域包括组织结构，其具有以下步骤：a）首先获取（110） 具有第一图像采集参数（114）的图像数据（112），其中所述第一图像参数适于双能量模式的第一辐射光谱; 并且其中以预扫描的低X射线剂量执行所述第一图像采集; b）利用第二图像获取参数（120）获取（116）第二图像数据（118），其中所述第二图像参数适于所述双能量模式的第二辐射光谱，并且其中所述第二图像采集具有较高的 X射线剂量比第一图像采集，并且其中第二图像采集是乳房X线照相术扫描; c）基于第一和第二图像数据执行（122）双能量基础材料分解（124）以产生分解的基础材料图像数据（126）; 以及d）从所分解的基础材料图像数据中导出（128）所述感兴趣区域的组织结构的密度信息（130）; 以及向用户提供（132）密度信息。

公开(公告)号：US08155422B2

公开(公告)日：2012-04-10

申请号：US12293835

申请日：2007-03-15

申请人： Andy Ziegler ,  Ewald Roessl

发明人： Andy Ziegler ,  Ewald Roessl

IPC分类号： G06K9/00

CPC分类号： G01T1/2985

摘要： It is described a method for dynamically optimizing the signal-to-noise ratio of attenuation data related to two different X-ray energies for reconstructing an image of an object under examination. The method comprises (a) estimating the thickness and the material composition of the object at a plurality of different projection angles, (b) for each of the various projection angles calculating for a variety of combinations of different first and second X-ray energies a corresponding common signal-to-noise ratio, (c) for each of the various projection angles choosing the first and the second X-ray energy causing the maximum corresponding common signal-to-noise ratio, and (d) for each of the various projection angles acquiring X-ray attenuation data of the object whereby the two X-ray energies are the X-ray energies causing a maximum signal-to-noise ratio assigned to the respective projection angle.

摘要翻译： 描述了一种用于动态优化与两个不同X射线能量相关的衰减数据的信噪比的方法，用于重建被检查物体的图像。 该方法包括：（a）以多个不同的投影角度估计物体的厚度和材料成分，（b）对于针对不同的第一和第二X射线能量的各种组合计算的各种投影角度中的每一个 相应的公共信噪比，（c）对于选择第一和第二X射线能量的各种投影角度中的每一个引起最大相应的公共信噪比，（d）对于各种各样的 投影角度获取物体的X射线衰减数据，由此两个X射线能量是分配给各个投影角度的最大信噪比的X射线能量。