公开(公告)号：US09269471B2

公开(公告)日：2016-02-23

申请号：US13260380

申请日：2010-03-15

申请人： Ewald Roessl ,  Thomas Koehler ,  Gerhard Martens

发明人： Ewald Roessl ,  Thomas Koehler ,  Gerhard Martens

IPC分类号： A61B6/03 ,  G21K7/00 ,  A61B6/00

CPC分类号： G21K7/00 ,  A61B6/4291 ,  A61B6/484 ,  A61B6/502

摘要： An X-ray differential phase-contrast imaging system has three circular gratings. The circular gratings are aligned with the optical axis of the radiation beam and a phase stepping is performed along the optical axis with the focal spot, the phase grating and/or the absorber grating. The signal measured is the phase-gradient in radial direction away from the optical axis.

摘要翻译： X射线差分相位成像系统具有三个圆形光栅。 圆形光栅与辐射束的光轴对准，并且沿着光轴与焦斑，相位光栅和/或吸收光栅一起执行相位步进。 测量的信号是远离光轴的径向相位梯度。

公开(公告)号：US20140169653A1

公开(公告)日：2014-06-19

申请号：US14236668

申请日：2012-07-27

申请人： Hanns-Ingo Maack ,  Ewald Roessl ,  Thomas Koehler ,  Roland Proska

发明人： Hanns-Ingo Maack ,  Ewald Roessl ,  Thomas Koehler ,  Roland Proska

IPC分类号： G06T11/60

CPC分类号： G06T11/60 ,  A61B6/484 ,  G06T5/50 ,  G06T2207/10116 ,  G06T2207/20056 ,  G06T2207/20221 ,  G06T2207/30004

摘要： The present invention relates to X-ray imaging technology. In phase-contrast imaging, different types of image information, e.g. absorption image information and differential phase-contrast image information, may be obtained by a single image acquisition process. Individual types of image information comprise different image properties. The present invention relates to a frequency dependent combination of different types of image information to obtain a combined image having improved properties over the individual image information and their respective image information type. Accordingly, an apparatus (56) as well as a method (100) for image processing in X-ray imaging of an object is provided comprising receiving (102) first image information of the object of a first image information type, receiving (104) second image information of the object of a second image information type,wherein the second image information type is different from the first image information type. Subsequently the first image information and the second image information is combined (106) to obtain combined image information of the object, wherein the combination of the first image information and the second image information is a frequency-dependent combination, depending on the spatial frequency of the first image information and the second image information.

摘要翻译： 本发明涉及X射线成像技术。 在相位对比成像中，不同类型的图像信息，例如， 吸收图像信息和差分相位差图像信息可以通过单个图像获取处理获得。 各种类型的图像信息包括不同的图像属性。 本发明涉及不同类型的图像信息的频率相关组合，以获得具有相对于各个图像信息及其各自的图像信息类型具有改进的特性的组合图像。 因此，提供了一种装置（56）以及用于对象的X射线成像中的图像处理的方法（100），包括接收（102）第一图像信息类型的对象的第一图像信息，接收（104） 第二图像信息类型的对象的第二图像信息，其中第二图像信息类型与第一图像信息类型不同。 随后，将第一图像信息和第二图像信息组合（106）以获得对象的组合图像信息，其中第一图像信息和第二图像信息的组合是频率相关组合，其取决于 第一图像信息和第二图像信息。

公开(公告)号：US20120243658A1

公开(公告)日：2012-09-27

申请号：US13514682

申请日：2010-12-03

申请人： Dieter Geller ,  Klaus Juergen Engel ,  Gereon Vogtmeier ,  Thomas Koehler ,  Ewald Roessl

发明人： Dieter Geller ,  Klaus Juergen Engel ,  Gereon Vogtmeier ,  Thomas Koehler ,  Ewald Roessl

IPC分类号： G01N23/04

CPC分类号： A61B6/00 ,  A61B6/4291 ,  A61B6/4441 ,  A61B6/484

摘要： X-ray devices for Phase Contrast Imaging (PCI) are often built up with the help of gratings. For large field-of-views (FOV), production cost and complexity of these gratings could increase significantly as they need to have a focused geometry. Instead of a pure PCI with a large FOV, this invention suggests to combine a traditional absorption X-ray-imaging system with large-FOV with an insertable low-cost PCI system with small-FOV, The invention supports the user to direct the PCI system with reduced FOV to a region that he regards as most interesting for performing a PCI scan thus eliminating X-ray dose exposure for scanning regions not interesting for a radiologist. The PCI scan may be generated on the basis of local tomography.

摘要翻译： 用于相位对比成像（PCI）的X射线装置通常在光栅的帮助下构建。 对于大视野（FOV）来说，这些光栅的生产成本和复杂性可能会因为需要聚焦几何而显着增加。 本发明不是采用具有大FOV的纯PCI，而是将传统的吸收X射线成像系统与大型FOV结合，并具有小FOV的可插入低成本PCI系统。本发明支持用户指导PCI 系统将FOV降低到他认为对于执行PCI扫描最有趣的区域，从而消除了用于放射科医生不感兴趣的扫描区域的X射线剂量曝光。 可以基于局部断层摄影产生PCI扫描。

公开(公告)号：US20120057676A1

公开(公告)日：2012-03-08

申请号：US13266692

申请日：2010-05-17

申请人： Thomas Koehler ,  Ewald Roessl

发明人： Thomas Koehler ,  Ewald Roessl

IPC分类号： G21K1/06

CPC分类号： G21K1/06 ,  G21K2207/005

摘要： The invention relates to gratings for X-ray differential phase-contrast imaging, a focus detector arrangement and X-ray system for generating phase-contrast images of an object and a method of phase-contrast imaging for examining an object of interest. In order to provide gratings with a high aspect ratio but low costs, a grating for X-ray differential phase-contrast imaging is proposed, comprising a first sub-grating (112), and at least a second sub- grating (114; 116; 118), wherein the sub-gratings each comprise a body structure (120) with bars (122) and gaps (124) being arranged periodically with a pitch (a), wherein the sub-gratings (112; 114; 116; 118) are arranged consecutively in the direction of the X-ray beam, and wherein the sub-gratings (112; 114; 116; 118) are positioned displaced to each other perpendicularly to the X-ray beam.

摘要翻译： 本发明涉及用于X射线差分相位对比成像的光栅，用于产生对象的相位对比图像的焦点检测器布置和X射线系统以及用于检查感兴趣对象的相位对比成像方法。 为了提供具有高纵横比但成本较低的光栅，提出了一种用于X射线差分相位对比成像的光栅，包括第一子光栅（112）和至少第二子光栅（114; 116 ; 118），其中所述子光栅各自包括具有杆（122）和间隙（124）的主体结构（120），所述杆具有间距（a）周期性地布置，其中所述子光栅（112; 114; 116; 118 ）沿X射线束的方向连续布置，并且其中子光栅（112; 114; 116; 118）被定位成垂直于X射线束彼此位移。

公开(公告)号：US09084528B2

公开(公告)日：2015-07-21

申请号：US13514682

申请日：2010-12-03

申请人： Dieter Geller ,  Klaus Juergen Engel ,  Gereon Vogtmeier ,  Thomas Koehler ,  Ewald Roessl

发明人： Dieter Geller ,  Klaus Juergen Engel ,  Gereon Vogtmeier ,  Thomas Koehler ,  Ewald Roessl

IPC分类号： G01N23/04 ,  A61B6/00

CPC分类号： A61B6/00 ,  A61B6/4291 ,  A61B6/4441 ,  A61B6/484

摘要： X-ray devices for Phase Contrast Imaging (PCI) are often built up with the help of gratings. For large field-of-views (FOV), production cost and complexity of these gratings could increase significantly as they need to have a focused geometry. Instead of a pure PCI with a large FOV, this invention suggests to combine a traditional absorption X-ray-imaging system with large-FOV with an insertable low-cost PCI system with small-FOV, The invention supports the user to direct the PCI system with reduced FOV to a region that he regards as most interesting for performing a PCI scan thus eliminating X-ray dose exposure for scanning regions not interesting for a radiologist. The PCI scan may be generated on the basis of local tomography.

摘要翻译： 用于相位对比成像（PCI）的X射线装置通常在光栅的帮助下构建。 对于大视野（FOV）来说，这些光栅的生产成本和复杂性可能会因为需要聚焦几何而显着增加。 本发明不是采用具有大FOV的纯PCI，而是将传统的吸收X射线成像系统与大型FOV结合，并具有小FOV的可插入低成本PCI系统。本发明支持用户指导PCI 系统将FOV降低到他认为对于执行PCI扫描最有趣的区域，从而消除了用于放射科医生不感兴趣的扫描区域的X射线剂量曝光。 可以基于局部断层摄影产生PCI扫描。

公开(公告)号：US09066649B2

公开(公告)日：2015-06-30

申请号：US13514383

申请日：2010-12-03

申请人： Ewald Roessl ,  Klaus Juergen Engel ,  Gereon Vogtmeier ,  Dieter Geller ,  Gerhard Martens ,  Sebastian Siegmund Schusser ,  Thomas Koehler

发明人： Ewald Roessl ,  Klaus Juergen Engel ,  Gereon Vogtmeier ,  Dieter Geller ,  Gerhard Martens ,  Sebastian Siegmund Schusser ,  Thomas Koehler

IPC分类号： A61B6/00 ,  A61B6/03

CPC分类号： A61B6/00 ,  A61B6/032 ,  A61B6/4021 ,  A61B6/4092 ,  A61B6/4291 ,  A61B6/484

摘要： An X-ray image acquisition apparatus employing phase-contrast imaging with enlarged field of view includes an X-ray source, an X-ray detector element having a detector size, a beam splitter grating and an analyzer grating. An object is arrangeable between the X-ray source and detector. The beam splitter grating and the analyzer grating are arrangeable between the X-ray source and detector. The X-ray source, the beam splitter grating, the analyzer grating and the X-ray detector are operatively coupled such that a phase-contrast image of the object is obtainable. The apparatus is configure to acquire a phase-contrast image having a field of view larger than the detector size. The X-ray detector element is displaceable where, by the displacement of the X-ray detector, a phase-contrast image of the enlarged field of view is obtainable.

摘要翻译： 采用具有放大视场的相位对比成像的X射线图像获取装置包括X射线源，具有检测器尺寸的X射线检测器元件，分束器光栅和分析器光栅。 X射线源和检测器之间可以配置一个物体。 分束器光栅和分析器光栅可以在X射线源和检测器之间布置。 X射线源，分束器光栅，分析器光栅和X射线检测器可操作地耦合，使得可以获得物体的相差图像。 该装置被配置为获取具有大于检测器尺寸的视场的相位对比度图像。 X射线检测器元件可移动，其中通过X射线检测器的位移可以获得放大视场的相位对比图像。

公开(公告)号：US08861674B2

公开(公告)日：2014-10-14

申请号：US13509840

申请日：2010-12-10

申请人： Thomas Koehler ,  Roland Proksa ,  Ewald Roessl

发明人： Thomas Koehler ,  Roland Proksa ,  Ewald Roessl

IPC分类号： A61B6/00 ,  A61B6/03 ,  G01N23/04 ,  G06T11/00

CPC分类号： A61B6/032 ,  A61B6/469 ,  A61B6/542 ,  G01N23/046 ,  G01N2223/419 ,  G06T11/005 ,  Y10S378/901

摘要： The invention relates to a computed tomography apparatus for imaging an object. The computed tomography apparatus comprises a radiation source (2) for generating modulated radiation (4) traversing the object and a detector (6) for generating detection values depending on the radiation (4) after having traversed the object, while the radiation source (2) and the object are moved relative to each other. A weight providing unit (14) provides modulation weights for weighting the detection values depending on the modulation of the radiation (4) and a reconstruction unit (15) reconstructs an image of the object, wherein the detection values are weighted based on the provided modulation weights and an image of the object is reconstructed from the weighted detection values. This can allow to optimize the dose application to the object by modulating the radiation accordingly, wherein the reconstructed images still have a high quality.

摘要翻译： 本发明涉及一种用于对物体成像的计算机断层摄影装置。 计算机断层摄影装置包括用于产生经过物体的调制辐射（4）的辐射源（2）和用于在穿过物体之后产生取决于辐射（4）的检测值的检测器（6），而辐射源 ）并且对象相对于彼此移动。 权重提供单元（14）根据辐射（4）的调制提供用于对检测值进行加权的调制权重，并且重建单元（15）重建对象的图像，其中基于所提供的调制对所述检测值进行加权 从加权检测值重建对象的权重和图像。 这可以通过相应地调节辐射来优化对物体的剂量应用，其中重建的图像仍然具有高质量。

公开(公告)号：US20130156284A1

公开(公告)日：2013-06-20

申请号：US13820179

申请日：2011-09-01

申请人： Thomas Koehler ,  Ewald Roessl

发明人： Thomas Koehler ,  Ewald Roessl

IPC分类号： G06T11/00

CPC分类号： G06T11/003 ,  A61B6/484 ,  G06T11/005 ,  G06T11/006

摘要： The present invention relates to differential phase-contrast imaging of an object (108). When reconstructing image information from differential phase-contrast image data, streak- like artefacts (502) may occur. The artefacts (502) may substantially reduce legibility of reconstructed image data. Accordingly, it may be beneficial for removing or at least suppressing said artefacts (502). Thus, a method (400) for regularized phase retrieval in phase-contrast imaging is provided comprising receiving (402) differential phase-contrast image data of an object (108); generating (404) reconstructed image data of an object (108) and presenting (406) reconstructed image data of the object (108). The differential phase-contrast image and the reconstructed image data comprise a two-dimensional data structure having a first dimension and a second dimension. Generating reconstructed image data comprises integration of image data in one of the first dimension and the second dimension of the data structure. A gradient operator is determined in the other one of the first dimension and second dimension of the data structure and the data structure is employed for reconstructing image data resulting in a reduction of artefacts (500) within the reconstructed image data.

摘要翻译： 本发明涉及物体（108）的差分相位对比成像。 当从差分相位差图像数据重建图像信息时，可能会出现条纹状伪像（502）。 人造物（502）可以大大降低重构图像数据的可读性。 因此，去除或至少抑制所述伪影（502）可能是有益的。 因此，提供了一种用于相位对比成像中的正则化相位检索的方法（400），包括：接收（402）对象（108）的差分相位对比图像数据; 生成（404）对象（108）的重建图像数据并呈现（406）对象（108）的重建图像数据。 差分相位对比图像和重构图像数据包括具有第一维度和第二维度的二维数据结构。 生成重构图像数据包括将图像数据集成在数据结构的第一维度和第二维度之一中。 在数据结构的第一维度和第二维度中的另一个维度中确定梯度算子，并且采用数据结构来重建图像数据，导致重构图像数据内的伪像（500）的减少。

公开(公告)号：US20120250821A1

公开(公告)日：2012-10-04

申请号：US13509840

申请日：2010-12-10

申请人： Thomas Koehler ,  Roland Proksa ,  Ewald Roessl

发明人： Thomas Koehler ,  Roland Proksa ,  Ewald Roessl

IPC分类号： G01N23/04

CPC分类号： A61B6/032 ,  A61B6/469 ,  A61B6/542 ,  G01N23/046 ,  G01N2223/419 ,  G06T11/005 ,  Y10S378/901

摘要： The invention relates to a computed tomography apparatus for imaging an object. The computed tomography apparatus comprises a radiation source (2) for generating modulated radiation (4) traversing the object and a detector (6) for generating detection values depending on the radiation (4) after having traversed the object, while the radiation source (2) and the object are moved relative to each other. A weight providing unit (14) provides modulation weights for weighting the detection values depending on the modulation of the radiation (4) and a reconstruction unit (15) reconstructs an image of the object, wherein the detection values are weighted based on the provided modulation weights and an image of the object is reconstructed from the weighted detection values. This can allow to optimize the dose application to the object by modulating the radiation accordingly, wherein the reconstructed images still have a high quality.

摘要翻译： 本发明涉及一种用于对物体成像的计算机断层摄影装置。 计算机断层摄影装置包括用于产生经过物体的调制辐射（4）的辐射源（2）和用于在穿过物体之后产生取决于辐射（4）的检测值的检测器（6），而辐射源 ）并且对象相对于彼此移动。 权重提供单元（14）根据辐射（4）的调制提供用于对检测值进行加权的调制权重，并且重建单元（15）重建对象的图像，其中基于所提供的调制对所述检测值进行加权 从加权检测值重建对象的权重和图像。 这可以通过相应地调节辐射来优化对物体的剂量应用，其中重建的图像仍然具有高质量。

公开(公告)号：US20120020461A1

公开(公告)日：2012-01-26

申请号：US13260424

申请日：2010-03-19

申请人： Ewald Roessl ,  Thomas Koehler

发明人： Ewald Roessl ,  Thomas Koehler

IPC分类号： G01N23/20

CPC分类号： G21K1/06 ,  G02B27/52 ,  G21K2207/005

摘要： An achromatic phase-contrast imaging apparatus for examining an object of interest is provided which comprises two different phase gratings which have different pitches. Thus, the imaging apparatus yields phase-contrast information for two different energies. Thus, phase-information over a wider energy band can be used.

摘要翻译： 提供一种用于检查感兴趣对象的消色差相位对比成像装置，其包括具有不同间距的两个不同的相位光栅。 因此，成像装置产生两个不同能量的相位对比度信息。 因此，可以使用较宽能带上的相位信息。