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公开(公告)号:US20160361670A1
公开(公告)日:2016-12-15
申请号:US15249129
申请日:2016-08-26
发明人: Bart Lipkens , Walter M. Presz, JR. , Jeffrey King , Jason Barnes , Dane Mealey , Brian McCarthy , Ben Ross-Johnsrud , Kedar Chitale
CPC分类号: B01D21/283 , B01D21/0042 , B01D21/0045 , B01D21/0087 , B01D21/2422 , B06B1/06 , C02F1/36 , C12M47/02
摘要: Devices for separating a host fluid from a second fluid or particulate are disclosed. The devices include an acoustic chamber, a fluid outlet at a top end of the acoustic chamber, a concentrate outlet at a bottom end of the acoustic chamber, and an inlet on a first side end of the acoustic chamber. An ultrasonic transducer and reflector create a multi-dimensional acoustic standing wave in the acoustic chamber that traps and separates particulates (e.g. cells) from a host fluid. The host fluid is collected via the fluid outlet, and the particulates are collected via the concentrate outlet. The device is a large-scale device that is able to process liters/hour, and has a large interior volume.
摘要翻译: 公开了用于从第二流体或颗粒分离主体流体的装置。 这些装置包括声室,在声腔的顶端处的流体出口,在声腔的底端处的浓缩物出口,以及在声室的第一侧端上的入口。 超声波换能器和反射器在声室中产生多维声驻波,其将微粒(例如电池)与主流体捕获并分离。 主流体通过流体出口收集,微粒通过浓缩物出口收集。 该装置是能够处理升/小时,并具有大的内部容积的大型装置。
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公开(公告)号:US20160089620A1
公开(公告)日:2016-03-31
申请号:US14870952
申请日:2015-09-30
发明人: Bart Lipkens , Jeff King , David Sokolowski , Anthony B. Masi , Brian T. Kennedy , Brian McCarthy , Benjamin Ross-Johnsrud , Jason Dionne , Dane Mealey , Jason Barnes
CPC分类号: B01D21/283 , B01D17/044 , B01D17/06 , B01D19/0078 , B06B1/06 , B06B1/0622 , B06B1/0644 , B06B2201/71 , C12M47/04 , C12N13/00
摘要: Acoustophoretic devices for separating particles from a non-flowing host fluid are disclosed. The devices include a substantially acoustically transparent container and a separation unit, with the container being placed within the separation unit. An ultrasonic transducer in the separation unit creates a planar or multi-dimensional acoustic standing wave within the container, trapping particles disposed within the non-flowing fluid and causing them to coalesce or agglomerate, then separate due to buoyancy or gravity forces.
摘要翻译: 公开了用于从非流动主流体分离颗粒的声学装置。 这些装置包括基本上声透明的容器和分离单元,容器被放置在分离单元内。 分离单元中的超声波换能器在容器内产生平面或多维声驻波,捕获设置在非流动流体内的颗粒,并使其聚结或附聚,然后由于浮力或重力而分离。
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公开(公告)号:US10710006B2
公开(公告)日:2020-07-14
申请号:US15497078
申请日:2017-04-25
发明人: Bart Lipkens , Jeffrey King , Jack Saloio , Brian McCarthy
摘要: Transducer assemblies that can be used in acoustophoretic systems are disclosed. The acoustophoretic systems including the transducer assemblies and methods of operating the acoustophoretic systems are also disclosed. The transducer assemblies include a housing, a polymeric film attached to the housing, and a piezoelectric material attached to the polymeric film. The piezoelectric material is not attached to, and does not come in direct contact with, the housing. The piezoelectric material is configured to be driven by a drive signal to create a multi-dimensional acoustic standing wave. The piezoelectric material can be attached to the polymer film by an adhesive coating on the polymer film.
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公开(公告)号:US20170304746A1
公开(公告)日:2017-10-26
申请号:US15497078
申请日:2017-04-25
发明人: Bart Lipkens , Jeffrey King , Jack Saloio , Brian McCarthy
摘要: Transducer assemblies that can be used in acoustophoretic systems are disclosed. The acoustophoretic systems including the transducer assemblies and methods of operating the acoustophoretic systems are also disclosed. The transducer assemblies include a housing, a polymeric film attached to the housing, and a piezoelectric material attached to the polymeric film. The piezoelectric material is not attached to, and does not come in direct contact with, the housing. The piezoelectric material is configured to be driven by a drive signal to create a multi-dimensional acoustic standing wave. The piezoelectric material can be attached to the polymer film by an adhesive coating on the polymer film.
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公开(公告)号:US09796956B2
公开(公告)日:2017-10-24
申请号:US15284529
申请日:2016-10-03
发明人: Bart Lipkens , Thomas J. Kennedy, III , Jeffrey King , Jason Barnes , Brian McCarthy , Dane Mealey , Erik Miller , Walter M. Presz, Jr. , Benjamin Ross-Johnsrud , John Rozembersky
CPC分类号: C12M33/08 , A61M1/3678 , B01D21/0045 , B01D21/283 , B06B1/0223 , B06B1/0276 , B06B1/06 , C12M47/02 , C12N13/00
摘要: An acoustophoresis device made up of modular components is disclosed. Several modules are disclosed herein, including ultrasonic transducer modules, input/output modules, collection well modules, and various connector modules. These permit different systems to be constructed that have appropriate fluid dynamics for separation of particles, such as biological cells, from a fluid.
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公开(公告)号:USD787630S1
公开(公告)日:2017-05-23
申请号:US29541602
申请日:2015-10-06
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