-
公开(公告)号：US11708572B2
公开(公告)日：2023-07-25
申请号：US16421459
申请日：2019-05-23
发明人： Bart Lipkens , Kedar C. Chitale , Krishna N. Kumar , Walter M. Presz, Jr. , Ruan Zhang , Benjamin Ross-Johnsrud , Rudolf Gilmanshin , Natalia Rodionova , Rui Tostoes
CPC分类号： C12N13/00 , A61M1/3678 , B01D21/283 , B01L3/502761 , C12M47/04 , G01N15/1484 , B01L2300/0864 , B01L2300/0867 , B01L2400/0436 , B01L2400/0439 , G01N2015/0053 , G01N2015/1006 , G01N2015/149
摘要： Beads with functionalized material applied to them are exposed to an acoustic field to trap, retain or pass the beads. The beads may include or be free of ferro magnetic material. The beads may be biocompatible or biodegradable for a host. The size of the beads may vary over a range, and/or be heterogenous or homogenous. The composition of the beads may include high, neutral or low acoustic contrast material. The chemistry of the functionalized material may be compatible with existing processes. The acoustic field may be generated, for example, in an acoustic angled wave device or in an acoustic fluidized bed.
-
公开(公告)号：US11459540B2
公开(公告)日：2022-10-04
申请号：US15983823
申请日：2018-05-18
发明人： Rui Tostoes , Bart Lipkens , Kedar Chitale , Benjamin Ross-Johnsrud , Walter M. Presz, Jr. , Jack Saloio
摘要： Separation of materials is achieved using affinity binding and acoustophoretic techniques. A column provided with a fluid mixture of materials for separation and support structures may be used with acoustic waves to block flow of the support structures. The support structures can have an affinity for one or more materials in the fluid mixture. By blocking flow of the support structures, materials bound or adhered to the support structure are also blocked.
-
公开(公告)号：US09783775B2
公开(公告)日：2017-10-10
申请号：US15432737
申请日：2017-02-14
发明人： Bart Lipkens , Louis Masi , Stanley Kowalski, III , Walter M. Presz, Jr. , Jason Dionne , Brian Dutra , Ari Mercado , Thomas J. Kennedy, III , Arthur Martin
CPC分类号： C12M47/02 , B01D17/04 , B01D17/06 , B01D21/283 , B01J19/10 , B01J19/18 , B06B1/0644 , C02F1/36 , C02F3/00 , C12M23/14 , C12M23/22 , C12M27/02 , C12M29/10 , C12M29/18 , C12M33/08 , C12M33/14 , C12M35/04 , C12M47/10
摘要： A perfusion bioreactor includes at least one ultrasonic transducer that can acoustically generate a multi-dimensional standing wave. The standing wave can be used to retain cells in the bioreactor, and can also be utilized to dewater or further harvest product from the waste materials produced in a bioreactor.
-
公开(公告)号：USD797887S1
公开(公告)日：2017-09-19
申请号：US29562478
申请日：2016-04-26
-
公开(公告)号：US09701955B2
公开(公告)日：2017-07-11
申请号：US15285434
申请日：2016-10-04
IPC分类号： B01D43/00 , C12N13/00 , B01D21/28 , H01L41/053 , B01D17/04 , B06B1/06 , C12M1/00 , H01L41/09 , H01L41/187
CPC分类号： C12N13/00 , B01D17/044 , B01D21/28 , B01D21/283 , B06B1/0644 , C12M47/02 , H01L41/053 , H01L41/0913 , H01L41/1876
摘要： A system having improved trapping force for acoustophoresis is described where the trapping force is improved by manipulation of the frequency of the ultrasonic transducer. The transducer includes a ceramic crystal. The crystal may be directly exposed to fluid flow. The crystal may be air backed, resulting in a higher Q factor.
-
公开(公告)号：US09512395B2
公开(公告)日：2016-12-06
申请号：US14533753
申请日：2014-11-05
发明人： Bart Lipkens , Jason Barnes , Dane Mealey , Walter M. Presz, Jr. , Stanley Kowalski, III , Louis Masi , Thomas J. Kennedy, III , Brian McCarthy , Ben Ross-Johnsrud
CPC分类号： C12M47/02 , A61M1/3678 , B01D21/0045 , B01D21/283 , B06B1/06 , C12M33/08 , C12M47/10
摘要： An acoustophoresis device made up of modular components is disclosed. Several modules are disclosed herein, including ultrasonic transducer modules, input/output modules, collection well modules, and various connector modules. These permit different systems to be constructed that have appropriate fluid dynamics for separation of particles, such as biological cells, from a fluid.
摘要翻译： 公开了一种由模块化部件组成的消声器。 本文公开了多个模块，包括超声换能器模块，输入/输出模块，收集井模块和各种连接器模块。 这些允许构建具有用于从流体分离颗粒（例如生物细胞）的适当流体动力学的不同系统。
-
公开(公告)号：US09272234B2
公开(公告)日：2016-03-01
申请号：US13943529
申请日：2013-07-16
发明人： Bart Lipkens , Jason Dionne , Ari Mercado , Brian Dutra , Walter M. Presz, Jr. , Thomas J. Kennedy, III , Louis Masi
CPC分类号： B01D17/04 , B01D43/00 , B06B1/0644 , C12M47/02
摘要： An acoustic standing wave is utilized to separate components from a multi-component fluid, such as oil from an oil-water mixture, in a fluid flow scheme with an acoustophoresis device. For example, the flow scheme and device allows for trapping of the oil as the oil coalesces, agglomerates, and becomes more buoyant than the water.
-
8.发明申请公开(公告)号：US20150176001A1
公开(公告)日：2015-06-25
申请号：US14557040
申请日：2014-12-01
IPC分类号： C12N13/00
CPC分类号： C12N13/00 , B01D17/044 , B01D21/28 , B01D21/283 , B06B1/0644 , C12M47/02 , H01L41/053 , H01L41/0913 , H01L41/1876
摘要： A system having improved trapping force for acoustophoresis is described where the trapping force is improved by manipulation of the frequency of the ultrasonic transducer. The transducer includes a ceramic crystal. The crystal may be directly exposed to fluid flow. The crystal may be air backed, resulting in a higher Q factor.
摘要翻译： 描述了通过操纵超声换能器的频率来改善捕获力的方法，其具有改善的吸引力的捕集力。 换能器包括陶瓷晶体。 晶体可能直接暴露于流体流动。 晶体可能是空气支撑的，导致更高的Q因子。
-
公开(公告)号：USD722674S1
公开(公告)日：2015-02-17
申请号：US29459244
申请日：2013-06-27
设计人： Bart Lipkens , Walter M. Presz, Jr.
-
公开(公告)号：US11474085B2
公开(公告)日：2022-10-18
申请号：US15963809
申请日：2018-04-26
发明人： Bart Lipkens , Rui Tostoes , Kedar C. Chitale , Benjamin Ross-Johnsrud , Walter M. Presz, Jr. , Jack Saloio
IPC分类号： G01N30/76 , G01N30/46 , G01N30/72 , G01N33/543 , B01D15/38 , B01D15/18 , C07K1/22 , G01N30/02 , C12M1/42 , C12N13/00
摘要： Separation of materials is achieved using affinity binding and acoustophoretic techniques. A column provided with a fluid mixture of materials for separation and support structures may be used with acoustic waves to block flow of the support structures. The support structures can have an affinity for one or more materials in the fluid mixture. By blocking flow of the support structures, materials bound or adhered to the support structure are also blocked.
-
-
-
-
-
-
-
-
-
搜索结果
43 条记录 (耗时 0.029 秒)
