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公开(公告)号：US20180344833A1
公开(公告)日：2018-12-06
申请号：US16008852
申请日：2018-06-14
Applicant: GenVec, Inc.
Inventor： Ping Chen , Duncan McVey , Douglas E. Brough , Joseph Bruder
IPC: A61K39/015
CPC classification number: A61K39/015 , A61K2039/5256 , A61K2039/53 , Y02A50/412
Abstract: The invention is directed to a composition comprising one or more polypeptides or one or more nucleic acid sequences that can induce a protective immune response against Plasmodium species that infect humans. The invention also is directed to a method of using such compositions to induce a protective immune response against a Plasmodium parasite in a mammal.
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公开(公告)号：US10059962B2
公开(公告)日：2018-08-28
申请号：US15482991
申请日：2017-04-10
Applicant: GenVec, Inc.
Inventor： Douglas E. Brough , Jason G. D. Gall , Duncan McVey
IPC: C12N15/86 , C07K14/005 , A61K48/00
CPC classification number: C12N15/86 , A61K48/00 , C07K14/005 , C12N7/00 , C12N2710/10322 , C12N2710/10333 , C12N2710/10343 , C12N2760/18034 , C12N2760/18522 , C12N2840/60
Abstract: The invention provides an adenovirus or adenoviral vector characterized by comprising one or more particular nucleic acid sequences or one or more particular amino acid sequences, or portions thereof, pertaining to, for example, an adenoviral pIX protein, DNA polymerase protein, penton protein, hexon protein, and/or fiber protein.
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公开(公告)号：US09833502B2
公开(公告)日：2017-12-05
申请号：US14441988
申请日：2013-11-12
Applicant: GenVec, Inc.
Inventor： Ping Chen , Duncan McVey , Douglas Brough , Joseph Bruder
IPC: A61K39/015 , A61K39/00
CPC classification number: A61K39/015 , A61K2039/5256 , A61K2039/53 , Y02A50/412
Abstract: The invention is directed to a composition comprising one or more polypeptides or one or more nucleic acid sequences that can induce a protective immune response against Plasmodium species that infect humans. The invention also is directed to a method of using such compositions to induce a protective immune response against a Plasmodium parasite in a mammal.
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24.发明授权公开(公告)号：US09580476B2
公开(公告)日：2017-02-28
申请号：US14349735
申请日：2012-10-05
Applicant: GenVec, Inc.
Inventor： Douglas E. Brough , Jason G. D. Gall , Duncan McVey
IPC: C07K14/005 , C12N15/86
CPC classification number: C07K14/005 , C12N15/86 , C12N2710/10322 , C12N2710/10333 , C12N2710/10343 , C12N2760/18034 , C12N2799/022
Abstract: The invention provides an adenovirus or adenoviral vector characterized by comprising a nucleic acid sequence encoding one or more Respiratory Syncytial Virus (RSV) antigens and one or more particular nucleic acid sequences or one or more particular amino acid sequences, or portions thereof, pertaining to, for example, an adenoviral pIX protein, DNA polymerase protein, penton protein, hexon protein, and/or fiber protein, as well as a method of inducing an immune response against RSV in a mammal by administering the adenovirus or adenoviral vector to the mammal.
Abstract translation: 本发明提供了腺病毒或腺病毒载体，其特征在于包含编码一种或多种呼吸道合胞病毒（RSV）抗原和一种或多种特定核酸序列或一个或多个特定氨基酸序列或其部分的核酸序列， 例如腺病毒pIX蛋白，DNA聚合酶蛋白，penton蛋白，六邻体蛋白和/或纤维蛋白，以及通过向哺乳动物施用腺病毒或腺病毒载体而在哺乳动物中诱导针对RSV的免疫应答的方法。
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公开(公告)号：US20150329834A1
公开(公告)日：2015-11-19
申请号：US14817910
申请日：2015-08-04
Applicant: GenVec, Inc.
Inventor： Jason Gall , Douglas Brough , Christoph Kahl , Duncan McVey
IPC: C12N7/00
CPC classification number: C07K14/005 , C12N7/00 , C12N15/86 , C12N2710/10322 , C12N2710/10332 , C12N2710/10343 , C12N2710/10352
Abstract: The invention provides methods for propagating a monkey adenovirus in a cell, including a human cell, comprising one or more gene products isolated from a human adenovirus. Also provided are methods for propagating wherein the monkey adenovirus comprises a nucleic acid sequence encoding a human adenovirus gene product. The invention further provides a monkey adenovirus, including a replication-deficient monkey adenovirus, obtained by such propagation methods.
Abstract translation: 本发明提供了在细胞中繁殖猴腺病毒的方法，包括人细胞，其包含从人腺病毒分离的一种或多种基因产物。 还提供了用于繁殖的方法，其中猴腺病毒包含编码人腺病毒基因产物的核酸序列。 本发明还提供了通过这种繁殖方法获得的猴腺病毒，其包括复制缺陷型猴腺病毒。
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Patent Agency Ranking
公开(公告)号：US11359214B2
公开(公告)日：2022-06-14
申请号：US17002064
申请日：2020-08-25
Applicant: GenVec, Inc.
Inventor： Douglas E. Brough , Jason G. D. Gall , Duncan McVey
IPC: C12N15/86 , C07K14/005 , C12N7/00 , A61K48/00
Abstract: The invention provides an adenovirus or adenoviral vector characterized by comprising one or more particular nucleic acid sequences or one or more particular amino acid sequences, or portions thereof, pertaining to, for example, an adenoviral pIX protein, DNA polymerase protein, penton protein, hexon protein, and/or fiber protein.
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公开(公告)号：US20190134183A1
公开(公告)日：2019-05-09
申请号：US16250654
申请日：2019-01-17
Applicant: Boehringer Ingelheim Animal Health USA Inc. , GENVEC INC. , THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by the Secretary of Homela
Inventor： Justin WIDENER , Leszlie Woodyard , Leonardo Siger , Douglas Brough , Damodar Ettyreddy , Jason Gall , Duncan McVey , Tom Burrage , Lauri Motes-Kreimeyer , Marc Fiorucci
Abstract: The present invention encompasses FMDV vaccines or compositions. The invention encompasses recombinant vectors encoding and expressing FMDV antigens, epitopes or immunogens which can be used to protect animals, in particular ovines, bovines, caprines, or swines, against FMDV.
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公开(公告)号：US20190055579A1
公开(公告)日：2019-02-21
申请号：US16043501
申请日：2018-07-24
Applicant: GenVec, Inc.
Inventor： Douglas E. Brough , Jason G.D. Gall , Duncan McVey
IPC: C12N15/86 , C12N7/00 , C07K14/005
Abstract: The invention provides an adenovirus or adenoviral vector characterized by comprising one or more particular nucleic acid sequences or one or more particular amino acid sequences, or portions thereof, pertaining to, for example, an adenoviral pIX protein, DNA polymerase protein, penton protein, hexon protein, and/or fiber protein.
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公开(公告)号：US10188721B2
公开(公告)日：2019-01-29
申请号：US15419418
申请日：2017-01-30
Applicant: MERIAL INC. , GENVEC INC. , THE UNITED STATES OF AMERICA, as represented by the Secretary of Homeland Security
Inventor： Justin Widener , Leszlie Woodyard , Leonardo Siger , Douglas Brough , Damodar Ettyreddy , Jason Gall , Duncan McVey , Tom Burrage , Lauri Motes-Kreimeyer , Marc Fiorucci
IPC: A61K39/135 , C07K14/005 , C12N7/00 , A61K39/12 , C12N15/86 , A61K39/00
Abstract: The present invention encompasses FMDV vaccines or compositions. The invention encompasses recombinant vectors encoding and expressing FMDV antigens, epitopes or immunogens which can be used to protect animals, in particular ovines, bovines, caprines, or swines, against FMDV.
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公开(公告)号：US20180153979A1
公开(公告)日：2018-06-07
申请号：US15800975
申请日：2017-11-01
Applicant: GenVec, Inc.
Inventor： Ping Chen , Duncan McVey , Douglas E. Brough , Joseph Bruder
IPC: A61K39/015 , A61K39/00
CPC classification number: A61K39/015 , A61K2039/5256 , A61K2039/53 , Y02A50/412
Abstract: The invention is directed to a composition comprising one or more polypeptides or one or more nucleic acid sequences that can induce a protective immune response against Plasmodium species that infect humans. The invention also is directed to a method of using such compositions to induce a protective immune response against a Plasmodium parasite in a mammal.
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