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    HIGH RESOLUTION ELECTROPHYSIOLOGY CATHETER
    21.
    发明申请
    HIGH RESOLUTION ELECTROPHYSIOLOGY CATHETER 审中-公开
    高分辨率电生理导管

    公开(公告)号：US20080243214A1

    公开(公告)日：2008-10-02

    申请号：US12056210

    申请日：2008-03-26

    申请人： Josef V. Koblish

    发明人： Josef V. Koblish

    IPC分类号： A61N1/05

    CPC分类号： A61B18/1492 ,  A61B5/0422 ,  A61B5/6855 ,  A61B2018/00577 ,  A61B2018/00642 ,  A61B2018/00791 ,  A61B2018/00797 ,  A61B2018/00839 ,  A61B2018/1467 ,  A61N1/05 ,  A61N1/056

    摘要： An electrophysiology medical probes, which may be incorporated into a system and used to perform an electrophysiology procedure, is provided. The medical probe comprises an elongated member (e.g., a flexible elongated member), and a metallic electrode mounted to the distal end of the elongated member. In one embodiment, the metallic electrode is cylindrically shaped and comprises a rigid body. The medical probe further comprises a plurality of microelectrodes (e.g., at least four microelectrodes) embedded within, and electrically insulated from, the metallic electrode, and at least one wire connected to the metallic electrode and the microelectrodes.

    摘要翻译： 提供可并入系统并用于执行电生理过程的电生理学医学探针。 医疗探针包括细长构件（例如，柔性细长构件）和安装到细长构件的远端的金属电极。 在一个实施例中，金属电极是圆柱形的并且包括刚体。 医疗探针还包括嵌入在金属电极内并与之绝缘的多个微电极（例如，至少四个微电极）和连接到金属电极和微电极的至少一根电线。

    MULTI-BEND STEERABLE MAPPING CATHETER
    22.
    发明申请
    MULTI-BEND STEERABLE MAPPING CATHETER 有权
    多功能可弯曲导管

    公开(公告)号：US20080076999A1

    公开(公告)日：2008-03-27

    申请号：US11470132

    申请日：2006-09-05

    申请人： Josef V. Koblish

    发明人： Josef V. Koblish

    IPC分类号： A61B5/04

    CPC分类号： A61M25/0147 ,  A61B5/042 ,  A61B5/0422 ,  A61B5/6852

    摘要： An electrophysiology catheter introduced through the groin and inferior vena cava into the right side of the heart comprises an elongate flexible shaft having a steerable distal section and a prolapsing section located proximally of the distal section. The distal section is inserted into the coronary sinus and a back-steering force is applied to the catheter to anchor the distal section therein, after which the catheter is further advanced to prolapse the prolapsing section against the high right atrium. Electrical pathways in both the coronary sinus and the high right atrium are mapped using respective electrode pairs carried on the distal and prolapsing sections of the catheter.

    摘要翻译： 通过腹股沟和下腔静脉导入心脏的右侧的电生理学导管包括细长的柔性轴，其具有可操纵的远侧部分和位于远端部分的近侧的脱垂部分。 将远端部分插入冠状窦中，并将后向转向力施加到导管上以将远端部分固定在其中，之后导管进一步前进以使脱垂部分抵靠高右心房脱垂。 使用在导管的远端和脱垂部分上承载的各自的电极对来映射冠状窦和高右心房两者中的电通路。

    Devices and methods for creating lesions in endocardial and surrounding tissue to isolate focal arrhythmia substrates
    24.
    发明授权
    Devices and methods for creating lesions in endocardial and surrounding tissue to isolate focal arrhythmia substrates 有权
    用于在心内膜和周围组织中产生损伤以分离局部心律失常底物的装置和方法

    公开(公告)号：US06917834B2

    公开(公告)日：2005-07-12

    申请号：US09975393

    申请日：2001-10-10

    申请人： Josef V. Koblish ,  Russell B. Thompson ,  James G. Whayne ,  Yi Yang ,  David K. Swanson ,  Sidney D. Fleischman

    发明人： Josef V. Koblish ,  Russell B. Thompson ,  James G. Whayne ,  Yi Yang ,  David K. Swanson ,  Sidney D. Fleischman

    IPC分类号： A61B18/00 ,  A61B18/14 ,  A61N1/00

    CPC分类号： A61B18/1492 ,  A61B2018/00023 ,  A61B2018/00065 ,  A61B2018/00214 ,  A61B2018/0022 ,  A61B2018/00238 ,  A61B2018/00267 ,  A61B2018/00273 ,  A61B2018/00285 ,  A61B2018/00357 ,  A61B2018/00702 ,  A61B2018/00791 ,  A61B2018/00797 ,  A61B2018/1435

    摘要： Devices and methods are provided for creating lesions in endocardial tissues surrounding a vessel opening to thereby isolate focal arrhythmia substrates, including an invasive catheter assembly comprising an elongate body having a longitudinal axis and first and second lumens, a first catheter having a distally mounted expandable anchor body disposed in the first lumen, and a second catheter having a distally mounted electrode disposed in the second lumen, the elongate body having a first distal opening accessing the first lumen through which the first catheter may be extended axially relative to the longitudinal axis of the elongate body and a second distal opening accessing the second lumen through which the second catheter may be extended at an angle relative to the longitudinal axis of the elongate body. The disclosed invention also includes an elongate catheter having an expandable electrode body mounted on one end, wherein the electrode body is configured to form an enlarged circumferential region when expanded, the enlarged circumferential region defining a distal facing surface of the electrode body, the distal facing surface including an area configured to emit radio frequency (RF) energy.

    摘要翻译： 提供了用于在围绕血管开口的心内膜组织中产生损伤的装置和方法，从而分离局部心律失常基底，包括侵入性导管组件，其包括具有纵轴和第一和第二腔的细长体，具有远端安装的可扩张锚的第一导管 主体设置在第一内腔中，第二导管具有设置在第二内腔中的远侧安装的电极，细长主体具有进入第一内腔的第一远端开口，第一导管可相对于第一内腔的纵向轴线轴向延伸穿过第一内腔， 细长体和进入第二内腔的第二远端开口，第二导管可以通过第二内腔相对于细长体的纵向轴线以一定角度延伸。 所公开的发明还包括具有安装在一端上的可膨胀电极体的细长导管，其中电极体被构造成在膨胀时形成扩大的周向区域，扩大的圆周区域限定电极体的远侧面， 表面，其包括被配置为发射射频（RF）能量的区域。

    Apparatus and methods for cryogenically ablating tissue and adjusting cryogenic ablation regions
    29.
    发明授权
    Apparatus and methods for cryogenically ablating tissue and adjusting cryogenic ablation regions 有权
    用于低温消融组织和调节低温消融区域的装置和方法

    公开(公告)号：US08480663B2

    公开(公告)日：2013-07-09

    申请号：US12432538

    申请日：2009-04-29

    申请人： Frank W. Ingle ,  Robert F. Bencini ,  Josef V. Koblish ,  Jonathan A. Wohlgemuth ,  Paul Roche

    发明人： Frank W. Ingle ,  Robert F. Bencini ,  Josef V. Koblish ,  Jonathan A. Wohlgemuth ,  Paul Roche

    IPC分类号： A61B18/18

    CPC分类号： A61B18/02 ,  A61B2017/22051 ,  A61B2017/22054 ,  A61B2018/00196 ,  A61B2018/0022 ,  A61B2018/0212 ,  A61B2018/0262 ,  A61M25/1011

    摘要： Apparatus and methods for performing cryogenic ablation of tissue and adjusting the size and/or location of a cryogenic cooling region. A cooling assembly may include tubes for dispensing and exhausting a coolant or refrigerant. One or both of the tubes may be moved, e.g., slidably adjusted, in order to adjust the location or size of a cryogenic ablation region. The cooling assembly may be integrated into cryogenic ablation devices including a cryogenic balloon device that includes an inner inflatable balloon and another balloon that is at least partially wrapped around the inner balloon and carries refrigerant for performing cryo-ablation. Electrodes permit electrical mapping of tissue before or after cryo-ablation to verify success of the procedure.

    摘要翻译： 用于对组织进行低温消融并调节低温冷却区域的尺寸和/或位置的装置和方法。 冷却组件可以包括用于分配和排出冷却剂或制冷剂的管。 一个或两个管可以被移动，例如可滑动地调节，以便调节低温消融区域的位置或尺寸。 冷却组件可以集成到低温消融装置中，包括低温球囊装置，其包括内部可充气球囊和至少部分地缠绕在内球囊周围并承载用于进行低温消融的制冷剂的另一球囊。 电极允许在低温消融之前或之后对组织进行电气测绘，以验证该程序的成功。