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    APPARATUS AND METHOD FOR CHILLING CRYO-ABLATION COOLANT AND RESULTING CRYO-ABLATION SYSTEM
    1.
    发明申请
    APPARATUS AND METHOD FOR CHILLING CRYO-ABLATION COOLANT AND RESULTING CRYO-ABLATION SYSTEM 有权
    冷冻消融冷却剂和结晶洗涤系统的设备和方法

    公开(公告)号：US20090281533A1

    公开(公告)日：2009-11-12

    申请号：US12432465

    申请日：2009-04-29

    Applicant: Frank W. Ingle ,  Leonard George ,  Raphael Hon ,  Joann Heberer

    Inventor： Frank W. Ingle ,  Leonard George ,  Raphael Hon ,  Joann Heberer

    IPC: A61B18/02

    CPC classification number: A61B18/02 ,  A61B2017/22051 ,  A61B2018/00166 ,  A61B2018/00172 ,  A61B2018/0022 ,  A61B2018/00577 ,  A61B2018/0212 ,  A61B2018/0262

    Abstract: Apparatus and methods for cooling liquid coolant, such as nitrous oxide, to be delivered to a cryo-ablation device such as a balloon catheter. A hose or conduit in fluid communication with the ablation device includes an outer member and inner tubes. A first inner tube disposed within a lumen of the outer member carries liquid coolant to the ablation device. Another inner tube also disposed within the lumen carries liquid coolant and terminates within the lumen such that gaseous coolant derived from liquid coolant flowing through the second inner tube flows within the lumen to cool or chill the first inner tube and liquid coolant carried by the first inner tube to the ablation device.

    Abstract translation: 用于冷却诸如一氧化二氮的液体冷却剂的装置和方法将被输送到诸如球囊导管的低温消融装置。 与消融装置流体连通的软管或导管包括外部构件和内部管。 设置在外部构件的内腔内的第一内管将液体冷却剂携带到消融装置。 还设置在内腔内的另一内管承载液体冷却剂并且终止在内腔内，使得源自流过第二内管的液体冷却剂的气态冷却剂在管腔内流动以冷却或冷却第一内管和由第一内管 管到消融装置。

    Static devices and methods to shrink tissues for incontinence
    2.
    发明授权
    Static devices and methods to shrink tissues for incontinence 有权
    用于收缩尿失禁的组织的静态装置和方法

    公开(公告)号：US07470271B2

    公开(公告)日：2008-12-30

    申请号：US10887076

    申请日：2004-07-07

    Applicant: Loren L. Roy ,  Frank W. Ingle ,  George A. Morrison ,  Brian J. Mosel

    Inventor： Loren L. Roy ,  Frank W. Ingle ,  George A. Morrison ,  Brian J. Mosel

    IPC: A61B18/18

    CPC classification number: A61N1/403

    Abstract: The invention provides improved devices, methods, and systems for repeatably and reliably contracting fascia and other support tissues, particularly for the treatment of urinary incontinence. Rather than relying on a surgeon's ability to observe, direct, and control the selective shrinking of pelvic support tissues, a relatively large surface of a tissue contraction system is placed statically against the target tissue. Sufficient controlled energy is transmitted from the surface into the engaged tissue to contract the tissue and inhibit incontinence (or otherwise provide the desired therapeutic results).

    Abstract translation: 本发明提供改进的装置，方法和系统，用于可重复地和可靠地收缩筋膜和其他支撑组织，特别是用于治疗尿失禁。 不依赖于外科医生观察，指导和控制骨盆支持组织的选择性收缩的能力，组织收缩系统的相对较大的表面静止地放置在靶组织上。 足够的受控能量从表面传递到接合组织中以收缩组织并抑制失禁（或以其它方式提供期望的治疗结果）。

    Ultrasonic transducer method
    4.
    发明授权
    Ultrasonic transducer method 失效
    超声波换能器方法

    公开(公告)号：US4691418A

    公开(公告)日：1987-09-08

    申请号：US895273

    申请日：1986-08-11

    Applicant: Frank W. Ingle ,  John P. Claude

    Inventor： Frank W. Ingle ,  John P. Claude

    IPC: B06B1/06 ,  G10K11/02 ,  G11B5/42

    CPC classification number: G10K11/02 ,  B06B1/0651 ,  Y10T29/42 ,  Y10T29/49169 ,  Y10T29/49174

    Abstract: An ultrasonic transducer assembly comprising an injection-molded body member, a pair of piezoelectric ceramic members and a multi-pin connector is described. The piezoelectric ceramic members are electrically connected to the multi-pin connector by means of thin metallic ribbons. When assembled, the transducer assembly is detachably inserted in recesses provided therefor in the end of a hand-held probe.

    Abstract translation: 描述了包括注射成型体部件，一对压电陶瓷部件和多针连接器的超声换能器组件。 压电陶瓷构件通过薄金属带电连接到多针连接器。 组装时，换能器组件可拆卸地插入到手持式探头末端所设置的凹槽中。

    Apparatus and methods for cryogenically ablating tissue and adjusting cryogenic ablation regions
    5.
    发明授权
    Apparatus and methods for cryogenically ablating tissue and adjusting cryogenic ablation regions 有权
    用于低温消融组织和调节低温消融区域的装置和方法

    公开(公告)号：US08480663B2

    公开(公告)日：2013-07-09

    申请号：US12432538

    申请日：2009-04-29

    Applicant: Frank W. Ingle ,  Robert F. Bencini ,  Josef V. Koblish ,  Jonathan A. Wohlgemuth ,  Paul Roche

    Inventor： Frank W. Ingle ,  Robert F. Bencini ,  Josef V. Koblish ,  Jonathan A. Wohlgemuth ,  Paul Roche

    IPC: A61B18/18

    CPC classification number: A61B18/02 ,  A61B2017/22051 ,  A61B2017/22054 ,  A61B2018/00196 ,  A61B2018/0022 ,  A61B2018/0212 ,  A61B2018/0262 ,  A61M25/1011

    Abstract: Apparatus and methods for performing cryogenic ablation of tissue and adjusting the size and/or location of a cryogenic cooling region. A cooling assembly may include tubes for dispensing and exhausting a coolant or refrigerant. One or both of the tubes may be moved, e.g., slidably adjusted, in order to adjust the location or size of a cryogenic ablation region. The cooling assembly may be integrated into cryogenic ablation devices including a cryogenic balloon device that includes an inner inflatable balloon and another balloon that is at least partially wrapped around the inner balloon and carries refrigerant for performing cryo-ablation. Electrodes permit electrical mapping of tissue before or after cryo-ablation to verify success of the procedure.

    Abstract translation: 用于对组织进行低温消融并调节低温冷却区域的尺寸和/或位置的装置和方法。 冷却组件可以包括用于分配和排出冷却剂或制冷剂的管。 一个或两个管可以被移动，例如可滑动地调节，以便调节低温消融区域的位置或尺寸。 冷却组件可以集成到低温消融装置中，包括低温球囊装置，其包括内部可充气球囊和至少部分地缠绕在内球囊周围并承载用于进行低温消融的制冷剂的另一球囊。 电极允许在低温消融之前或之后对组织进行电气测绘，以验证该程序的成功。

    Devices, methods, and systems for shrinking tissues
    6.
    发明授权
    Devices, methods, and systems for shrinking tissues 有权
    用于收缩组织的装置，方法和系统

    公开(公告)号：US07689290B2

    公开(公告)日：2010-03-30

    申请号：US10866052

    申请日：2004-06-10

    Applicant: Frank W. Ingle ,  Garry L. Carter ,  Michael D. Laufer

    Inventor： Frank W. Ingle ,  Garry L. Carter ,  Michael D. Laufer

    IPC: A61F2/00

    CPC classification number: A61N1/403 ,  A61B18/14 ,  A61B18/1477 ,  A61B18/1482 ,  A61B18/1492 ,  A61B2018/00083 ,  A61B2018/00095 ,  A61B2018/00148 ,  A61B2018/00214 ,  A61B2018/00232 ,  A61B2018/00505 ,  A61B2018/00517 ,  A61B2018/00523 ,  A61B2018/00553 ,  A61B2018/00559 ,  A61B2018/00898 ,  A61B2018/126 ,  A61B2018/1425 ,  A61B2018/1467 ,  A61N1/06

    Abstract: Devices, systems, and method for treating urinary incontinence generally relying on energy delivered to a patient's pelvic support tissue to selectively contract or shrink at least a portion of that pelvic support tissue so as to reposition the bladder. The energy will preferably be applied to the endopelvic fascia and/or an arcus tendineus fascia pelvis. A variety of devices and methods are provided for applying gentle resistive heating of these and other tissues to cause them to contract without imposing significant injury on the surrounding tissue structures. By applying sufficient energy over a predetermined time, the tissue can be raised to a temperature which results in contraction without significant necrosis or other tissue damage. By selectively contracting the support tissues, the bladder neck, sphincter, and other components of the urinary tract responsible for the control of urinary flow can be reconfigured or supported in a manner which reduces urinary leakage.

    Abstract translation: 用于治疗尿失禁的装置，系统和方法通常依赖于递送至患者的骨盆支撑组织的能量以选择性地收缩或收缩该盆腔支撑组织的至少一部分，以便重新定位膀胱。 能量将优选地应用于内耳筋膜和/或腱骨筋膜骨盆。 提供了各种装置和方法来施加这些和其他组织的温和电阻加热，以使它们收缩而不对周围组织结构造成重大伤害。 通过在预定时间内施加足够的能量，组织可以升高到导致收缩而不显着坏死或其他组织损伤的温度。 通过选择性地收缩支撑组织，可以以减少尿液泄漏的方式重新配置或支撑膀胱颈，括约肌和负责控制尿流的尿道的其他成分。

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