公开(公告)号：US20120233716A1

公开(公告)日：2012-09-13

申请号：US13511386

申请日：2010-11-23

申请人： Jörg Bauer ,  Xiao Qiu ,  Patricia Vrinten

发明人： Jörg Bauer ,  Xiao Qiu ,  Patricia Vrinten

IPC分类号： C12N9/02 ,  C12N1/13 ,  C12N1/15 ,  C12N1/21 ,  C12N1/19 ,  C07K16/40 ,  C12P7/64 ,  C12N15/53 ,  A01H5/00 ,  A01H5/10 ,  A01K67/027 ,  C07C57/03 ,  C12N15/63 ,  C12N5/10

CPC分类号： C12N9/1029 ,  C12N9/0083 ,  C12N15/8247 ,  C12P7/6427 ,  Y02P20/52

摘要： The present invention relates to nucleic acids derived from Sphaeroforma arctica. The invention also relates to the individual coding sequences and to proteins encoded by these sequences in combination with other sequences as well as to a process for converting oleic acid to linoleic acid to linoleic acid and the production of arachidonic acid, eicosapentaenoic acid and/or docosahexaenoic acid in a plant.

摘要翻译： 本发明涉及来源于Sphaeroforma arctica的核酸。 本发明还涉及个体编码序列和由这些序列与其它序列组合编码的蛋白质以及将油酸转化为亚油酸至亚油酸的方法，以及花生四烯酸，二十碳五烯酸和/或二十二碳六烯酸 酸在植物中。

公开(公告)号：US07977469B2

公开(公告)日：2011-07-12

申请号：US12538227

申请日：2009-08-10

申请人： Xiao Qiu ,  Haiping Hong

发明人： Xiao Qiu ,  Haiping Hong

IPC分类号： C07H21/04 ,  C12N1/20 ,  C12N5/10

CPC分类号： C12N15/8247 ,  A23K20/158 ,  A23L33/12 ,  A23V2002/00 ,  A61K31/202 ,  A61K38/00 ,  C12N9/0071 ,  C12N9/0083 ,  C12P7/6427 ,  C12P7/6472 ,  C12Y114/19003 ,  Y02P20/52

摘要： The invention provides isolated nucleic acid molecules which encode novel fatty acid desaturase family members. The invention also provides recombinant expression vectors containing desaturase nucleic acid molecules, host cells into which the expression vectors have been introduced, and methods for large-scale production of long chain polyunsaturated fatty acids (LCPUFAs), e.g., DHA.

摘要翻译： 本发明提供编码新型脂肪酸去饱和酶家族成员的分离的核酸分子。 本发明还提供了含有去饱和酶核酸分子的重组表达载体，已引入表达载体的宿主细胞，以及大规模生产长链多不饱和脂肪酸（LCPUFA）如DHA的方法。

公开(公告)号：US07923598B2

公开(公告)日：2011-04-12

申请号：US11767115

申请日：2007-06-22

申请人： Dauenpen Meesapyodsuk ,  Xiao Qiu

发明人： Dauenpen Meesapyodsuk ,  Xiao Qiu

IPC分类号： C12N15/80 ,  C12N15/81 ,  C12N15/82 ,  C07H21/04 ,  C12N5/14

CPC分类号： C12P7/6409 ,  C07C51/42 ,  C07C51/47 ,  C07C51/48 ,  C11B1/025 ,  C12N9/0071 ,  C12N15/8247 ,  C12P7/6463

摘要： The invention provides isolated nucleic acid molecules which encode novel fatty acid hydroxylases. The invention also provides recombinant expression vectors including hydroxylase nucleic acid molecules, host cells into which the expression vectors have been introduced, and methods for the production of hydroxyl fatty acids such as 12-hydroxyoctadec-9-enoic acid (ricinoleic acid).

摘要翻译： 本发明提供编码新型脂肪酸羟化酶的分离的核酸分子。 本发明还提供了重组表达载体，包括羟化酶核酸分子，已经引入表达载体的宿主细胞，以及生产羟基脂肪酸如12-羟基十八碳-9-烯酸（蓖麻醇酸）的方法。

公开(公告)号：US20090055973A1

公开(公告)日：2009-02-26

申请号：US11883134

申请日：2006-02-07

申请人： Patricia Vrinten ,  Xiao Qiu

发明人： Patricia Vrinten ,  Xiao Qiu

IPC分类号： C12N15/11 ,  C12N15/82 ,  C12N5/10 ,  C07K14/00 ,  A01H5/00 ,  C12Q1/68

CPC分类号： C12N15/8234 ,  C12N9/0083 ,  C12N15/8247

摘要： The present invention relates to the isolation of a second omega-3 fatty acid desaturase (FAD3) gene in flax (Linum usitatissimum) and its promoter region, as well as the identification of FAD3 mutant alleles, and the development of markers for wild type and mutated alleles. The FAD3 genes encode the enzymes which control omega-3 fatty acid desaturation and, thus, the levels of linolenic acid (18:3(n-3)). Accordingly, the molecules of the present invention can be utilized, for example, to develop markers for the mutations in flax FAD3 genes and for seed-specific modification of fatty acid and protein compositions in plant seeds.

摘要翻译： 本发明涉及在亚麻（Linum usitatissimum）及其启动子区域中分离第二个ω-3脂肪酸去饱和酶（FAD3）基因，以及FAD3突变体等位基因的鉴定，以及野生型和 突变等位基因 FAD3基因编码控制ω-3脂肪酸去饱和的酶，从而编码亚麻酸（18：3（n-3））的水平。 因此，本发明的分子可以用于例如开发亚麻FAD3基因突变的标记物，以及植物种子中脂肪酸和蛋白质组合物的种子特异性修饰。

公开(公告)号：US07473820B2

公开(公告)日：2009-01-06

申请号：US11655545

申请日：2007-01-19

申请人： Xiao Qiu ,  Martin Truksa ,  Zhiyuan Hu

发明人： Xiao Qiu ,  Martin Truksa ,  Zhiyuan Hu

IPC分类号： C12P7/62 ,  C12P11/00 ,  C07H21/04 ,  A01H1/00

CPC分类号： C12N15/8234 ,  C07K14/415 ,  C12N15/8247

摘要： The present invention is directed to promoters of flax conlinin and ω-3 desaturase genes. The promoters guide high levels of the expression exclusively in flax developing seeds. This specific expression pattern concomitant with the biosynthesis of storage lipids and proteins make these promoters particularly useful for seed-specific modification of fatty acid and protein compositions in plant seeds.

摘要翻译： 本发明涉及亚麻精蛋白和ω-3去饱和酶基因的启动子。 启动子引导高水平的表达专门在亚麻发育种子。 这种特异性表达模式伴随着储存脂质和蛋白质的生物合成，使得这些启动子特别适用于植物种子中脂肪酸和蛋白质组成的种子特异性修饰。

公开(公告)号：US07087432B2

公开(公告)日：2006-08-08

申请号：US09967477

申请日：2001-09-28

申请人： Xiao Qiu ,  Haiping Hong

发明人： Xiao Qiu ,  Haiping Hong

IPC分类号： C12N15/82 ,  C12N15/74 ,  C07H21/04

CPC分类号： C12N15/8247 ,  A23K20/158 ,  A23L33/12 ,  A23V2002/00 ,  A61K31/202 ,  A61K38/00 ,  C12N9/0071 ,  C12N9/0083 ,  C12P7/6427 ,  C12P7/6472 ,  C12Y114/19003 ,  Y02P20/52

摘要： The invention provides isolated nucleic acid molecules which encode novel fatty acid desaturase family members. The invention also provides recombinant expression vectors containing desaturase nucleic acid molecules, host cells into which the expression vectors have been introduced, and methods for large-scale production of long chain polyunsaturated fatty acids (LCPUFAs), e.g., DHA.

公开(公告)号：US08841512B2

公开(公告)日：2014-09-23

申请号：US12336184

申请日：2008-12-16

申请人： Xiao Qiu ,  Martin Truksa ,  Zhiyuan Hu

发明人： Xiao Qiu ,  Martin Truksa ,  Zhiyuan Hu

IPC分类号： C12N15/82 ,  A01H5/00 ,  C12N5/10 ,  C07H21/04 ,  C07K14/415

CPC分类号： C12N15/8234 ,  C07K14/415 ,  C12N15/8247

摘要： The present invention is directed to promoters of flax conlinin and ω-3 desaturase genes. The promoters guide high levels of the expression exclusively in flax developing seeds. This specific expression pattern concomitant with the biosynthesis of storage lipids and proteins make these promoters particularly useful for seed-specific modification of fatty acid and protein compositions in plant seeds.

摘要翻译： 本发明涉及亚麻精蛋白和ω-3去饱和酶基因的启动子。 启动子引导高水平的表达专门在亚麻发育种子。 这种特异性表达模式伴随着储存脂质和蛋白质的生物合成，使得这些启动子特别适用于植物种子中脂肪酸和蛋白质组成的种子特异性修饰。

公开(公告)号：US20110229944A1

公开(公告)日：2011-09-22

申请号：US13150656

申请日：2011-06-01

申请人： Xiao Qiu ,  Haiping Hong

发明人： Xiao Qiu ,  Haiping Hong

IPC分类号： C12P7/64 ,  C07H21/00 ,  C12N15/63 ,  C12N5/10 ,  C12N1/00 ,  C12N1/13

CPC分类号： C12N15/8247 ,  A23K20/158 ,  A23L33/12 ,  A23V2002/00 ,  A61K31/202 ,  A61K38/00 ,  C12N9/0071 ,  C12N9/0083 ,  C12P7/6427 ,  C12P7/6472 ,  C12Y114/19003 ,  Y02P20/52

摘要： The invention provides isolated nucleic acid molecules which encode novel fatty acid desaturase family members. The invention also provides recombinant expression vectors containing desaturase nucleic acid molecules, host cells into which the expression vectors have been introduced, and methods for large-scale production of long chain polyunsaturated fatty acids (LCPUFAs), e.g., DHA.

摘要翻译： 本发明提供编码新型脂肪酸去饱和酶家族成员的分离的核酸分子。 本发明还提供了含有去饱和酶核酸分子的重组表达载体，已引入表达载体的宿主细胞，以及大规模生产长链多不饱和脂肪酸（LCPUFA）如DHA的方法。

公开(公告)号：US20090031454A1

公开(公告)日：2009-01-29

申请号：US11767115

申请日：2007-06-22

申请人： Dauenpen Meesapyodsuk ,  Xiao Qiu

发明人： Dauenpen Meesapyodsuk ,  Xiao Qiu

IPC分类号： A01H5/00 ,  C07H21/04 ,  C12N15/63 ,  C12N5/04 ,  C12N1/16 ,  C12N1/14 ,  C12N1/12 ,  C11B1/00 ,  C12P21/06 ,  C07K14/37 ,  C12N9/02 ,  C12P7/64 ,  C12N15/74

CPC分类号： C12P7/6409 ,  C07C51/42 ,  C07C51/47 ,  C07C51/48 ,  C11B1/025 ,  C12N9/0071 ,  C12N15/8247 ,  C12P7/6463

摘要： The invention provides isolated nucleic acid molecules which encode novel fatty acid hydroxylases. The invention also provides recombinant expression vectors including hydroxylase nucleic acid molecules, host cells into which the expression vectors have been introduced, and methods for the production of hydroxyl fatty acids such as 12-hydroxyoctadec-9-enoic acid (ricinoleic acid).

摘要翻译： 本发明提供编码新型脂肪酸羟化酶的分离的核酸分子。 本发明还提供了重组表达载体，包括羟化酶核酸分子，已经引入表达载体的宿主细胞，以及生产羟基脂肪酸如12-羟基十八碳-9-烯酸（蓖麻醇酸）的方法。

公开(公告)号：US20060117414A1

公开(公告)日：2006-06-01

申请号：US11342731

申请日：2006-01-30

申请人： Xiao Qiu ,  Haiping Hong

发明人： Xiao Qiu ,  Haiping Hong

IPC分类号： A01H1/00 ,  C07H21/04 ,  C12N9/04 ,  C12N15/82 ,  C12N5/04

CPC分类号： C12N15/8247 ,  A23K20/158 ,  A23L33/12 ,  A23V2002/00 ,  A61K31/202 ,  A61K38/00 ,  C12N9/0071 ,  C12N9/0083 ,  C12P7/6427 ,  C12P7/6472 ,  C12Y114/19003 ,  Y02P20/52

摘要： The invention provides isolated nucleic acid molecules which encode novel fatty acid desaturase family members. The invention also provides recombinant expression vectors containing desaturase nucleic acid molecules, host cells into which the expression vectors have been introduced, and methods for large-scale production of long chain polyunsaturated fatty acids (LCPUFAs), e.g., DHA.

摘要翻译： 本发明提供编码新型脂肪酸去饱和酶家族成员的分离的核酸分子。 本发明还提供了含有去饱和酶核酸分子的重组表达载体，已引入表达载体的宿主细胞，以及大规模生产长链多不饱和脂肪酸（LCPUFA）如DHA的方法。