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公开(公告)号:US07094221B2
公开(公告)日:2006-08-22
申请号:US10790026
申请日:2004-03-02
IPC分类号: A61M5/00
CPC分类号: A61M5/31585 , A61M5/31535 , A61M5/31541 , A61M5/31551 , A61M5/3156 , A61M5/3158 , A61M2205/581 , A61M2205/582
摘要: A drive mechanism suitable for use in drug delivery devices is disclosed. The drive mechanism may be used with injector-type drug delivery devices, such as those permitting a user to set the delivery dose. The drive mechanism may include a housing, a dose dial sleeve having a helical thread of a first lead, and a two-part piston rod. The two-part piston rod may include an outer part having a helical thread of a second lead and an inner part having a helical thread of a third lead. In such an embodiment, the first lead of the thread of the dose dial sleeve may be equal to the sum of the second lead of the thread of the outer part of the piston rod and the third lead of the thread of the inner part of the piston rod.
摘要翻译: 公开了一种适用于药物输送装置的驱动机构。 驱动机构可以与注射器型药物递送装置一起使用,例如允许用户设定递送剂量的那些。 驱动机构可以包括壳体,具有第一引线的螺旋螺纹的剂量拨号套筒和两部分活塞杆。 两部分活塞杆可以包括具有第二引线的螺旋螺纹的外部部分和具有第三引线的螺旋螺纹的内部部分。 在这种实施例中,剂量拨片套筒的螺纹的第一引线可以等于活塞杆的外部部分的螺纹的第二引线与第二引线的内部的线的第三引线的总和 活塞杆。
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公开(公告)号:US09205197B2
公开(公告)日:2015-12-08
申请号:US12357899
申请日:2009-01-22
申请人: Christoph Dette , Paul Jansen , Christian Pommereau , Robert Frederick Veasey , Robert Perkins , David Aubrey Plumptre
发明人: Christoph Dette , Paul Jansen , Christian Pommereau , Robert Frederick Veasey , Robert Perkins , David Aubrey Plumptre
CPC分类号: A61M5/31551 , A61M5/002 , A61M5/24 , A61M5/31533 , A61M5/31535 , A61M5/3156 , A61M5/31565 , A61M5/31575 , A61M5/31585 , A61M5/3202 , A61M2005/2407 , A61M2005/3125 , A61M2005/3126 , A61M2205/581 , A61M2205/582 , A61M2205/586
摘要: A method and system for proving a drug delivery device. The device comprises a drug delivery device housing and a medicament contained in the drug delivery device housing. A dose dial sleeve is positioned in the housing and is rotatable to set a non-inverted dose of the medicament contained in the medical delivery device. The non-inverted dose may be increased by turning the dose dial sleeve in a direction towards a user of the drug delivery device. The dose medicament may be decreased by rotating the dose dial sleeve in a direction away from the user.
摘要翻译: 用于证明药物递送装置的方法和系统。 该装置包括药物输送装置壳体和药物输送装置壳体中所含的药物。 剂量拨号套筒定位在壳体中并且可旋转以设置包含在医疗输送装置中的药物的非倒置剂量。 可以通过朝向药物递送装置的使用者的方向转动剂量拨盘套筒来增加非倒置剂量。 可以通过沿远离用户的方向旋转剂量拨盘套筒来减少剂量药物。
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公开(公告)号:US09028454B2
公开(公告)日:2015-05-12
申请号:US12941702
申请日:2010-11-08
CPC分类号: A61M5/24 , A61M5/31528 , A61M5/31533 , A61M5/31535 , A61M5/31536 , A61M5/31541 , A61M5/31546 , A61M5/31551 , A61M5/3156 , A61M5/31563 , A61M5/31565 , A61M5/31568 , A61M5/3157 , A61M5/31575 , A61M5/31578 , A61M5/31585 , A61M5/31593 , A61M5/32 , A61M2005/2407 , A61M2005/3126 , A61M2205/581 , A61M2205/582
摘要: A drive mechanism suitable for use in drug delivery devices is disclosed. The drive mechanism may be used with injector-type drug delivery devices, such as those permitting a user to set the delivery dose. The drive mechanism may include a housing, a dose dial sleeve, and a drive sleeve. A clutch is configured to permit rotation of the drive sleeve and the dose dial sleeve with respect to the housing when the dose dial sleeve and drive sleeve are coupled through the clutch. Conversely, when the dose dial sleeve and drive sleeve are in a de-coupled state, rotation of the dose dial sleeve with respect to the housing is permitted and rotation of the drive sleeve with respect to the housing is prevented. In the de-coupled state, axial movement of the drive sleeve transfers force in a longitudinal direction for actuation of a drug delivery device.
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公开(公告)号:US08992486B2
公开(公告)日:2015-03-31
申请号:US13909681
申请日:2013-06-04
CPC分类号: A61M5/24 , A61M5/31528 , A61M5/31533 , A61M5/31535 , A61M5/31536 , A61M5/31541 , A61M5/31546 , A61M5/31551 , A61M5/3156 , A61M5/31563 , A61M5/31565 , A61M5/31568 , A61M5/3157 , A61M5/31575 , A61M5/31578 , A61M5/31585 , A61M5/31593 , A61M5/32 , A61M2005/2407 , A61M2005/3126 , A61M2205/581 , A61M2205/582
摘要: A housing for a dispensing apparatus. The housing comprising a main housing and a dose dial sleeve. The dose dial sleeve comprising a helical groove configured to engage a threading provided by the housing. A dose knob is disposed near a proximal end of the dose dial sleeve and a piston rod is provided within the housing. The piston rod is non-rotatable during a dose setting step. A driver comprises an internal threading near a distal portion of the driver and is adapted to engage an external thread of the piston rod. A tubular clutch is located adjacent a distal end of the dose knob and operatively coupled to the dose knob. The dose dial sleeve may extend circumferentially around at least a portion of the tubular clutch.
摘要翻译: 用于分配装置的壳体。 壳体包括主壳体和剂量拨盘套筒。 剂量拨盘套筒包括构造成接合由壳体提供的螺纹的螺旋槽。 剂量旋钮设置在剂量拨盘套筒的近端附近,并且活塞杆设置在壳体内。 活塞杆在剂量设定步骤期间是不可旋转的。 驱动器包括靠近驾驶员远端部分的内螺纹,并适于接合活塞杆的外螺纹。 管状离合器定位在剂量旋钮的远端附近并且可操作地耦合到剂量旋钮。 剂量拨片套筒可围绕管状离合器的至少一部分周向延伸。
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公开(公告)号:US20120240656A1
公开(公告)日:2012-09-27
申请号:US13430066
申请日:2012-03-26
申请人: Barry Crane , Ian Francis , Robert Perkins , William Paterson
发明人: Barry Crane , Ian Francis , Robert Perkins , William Paterson
IPC分类号: G01N33/00
CPC分类号: G01N35/00693 , A61B5/14532 , A61B5/14546 , A61B5/1459 , A61B5/1495 , G01N27/3274
摘要: A sensor kit comprising a sensor for detecting an analyte, a sensor housing and a calibration chamber. The calibration chamber comprises a first compartment containing a first calibration solution and a second compartment containing a source of the analyte to be detected. A dividing material is located between the first and second compartments enabling them to be mixed on breakage or removal of the dividing material. Further compartment(s) containing further source(s) of the analyte may optionally be provided. Calibration can carried out by (a) taking a reading of the analyte concentration of the first calibration solution, (b) mixing the contents of the first and second compartments by breaking or removing the dividing material, and (c) taking a reading of the analyte concentration of the resulting mixture. Steps (b) and (c) can be repeated for further compartment(s) to provide further reading(s) if desired.
摘要翻译: 传感器套件,包括用于检测分析物的传感器,传感器外壳和校准室。 校准室包括含有第一校准溶液的第一隔室和含有待检测分析物源的第二隔室。 分隔材料位于第一和第二隔室之间,使得它们能够在破碎或除去分隔材料时混合。 还可以提供含有其他进一步来源的进一步的隔室。 校准可以通过(a)读取第一校准溶液的分析物浓度来进行,(b)通过破碎或除去分割材料混合第一和第二隔室的内容物,以及(c)读取 所得混合物的分析物浓度。 如果需要,步骤(b)和(c)可以重复进一步的隔室以提供进一步的读数。
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公开(公告)号:US20120102516A1
公开(公告)日:2012-04-26
申请号:US13379857
申请日:2010-07-09
申请人: Robert Perkins
发明人: Robert Perkins
CPC分类号: H04H60/64 , H04H20/14 , H04H60/37 , H04H60/43 , H04H60/76 , H04H2201/37 , H04H2201/40 , H04H2201/90
摘要: Supplementary data associated with a broadcast transmission (5, 26) is made available to the viewer by identifying the content currently being received at a user terminal (2). The user generates a request for data which includes the identity of the broadcast content. This request is transmitted from the user terminal (2) to a content provision platform (4). The content provision platform retrieves supplementary data associated with the identified broadcast content and delivers the supplementary data to a predetermined return address (9).
摘要翻译: 通过识别用户终端(2)当前正在接收的内容,向观众提供与广播传输相关联的补充数据(5,26)。 用户生成包括广播内容的身份的数据的请求。 该请求从用户终端(2)发送到内容提供平台(4)。 内容提供平台检索与所识别的广播内容相关联的补充数据,并将补充数据传送到预定的返回地址(9)。
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公开(公告)号:US07935088B2
公开(公告)日:2011-05-03
申请号:US11520598
申请日:2006-09-14
IPC分类号: A61M5/00
CPC分类号: A61M5/24 , A61M5/31528 , A61M5/31533 , A61M5/31535 , A61M5/31536 , A61M5/31541 , A61M5/31546 , A61M5/31551 , A61M5/3156 , A61M5/31563 , A61M5/31565 , A61M5/31568 , A61M5/3157 , A61M5/31575 , A61M5/31578 , A61M5/31585 , A61M5/31593 , A61M5/32 , A61M2005/2407 , A61M2005/3126 , A61M2205/581 , A61M2205/582
摘要: A drive mechanism suitable for use in drug delivery devices is disclosed. The drive mechanism may be used with injector-type drug delivery devices, such as those permitting a user to set the delivery dose. The drive mechanism may include a housing, a dose dial sleeve, and a drive sleeve. A clutch is configured to permit rotation of the drive sleeve and the dose dial sleeve with respect to the housing when the dose dial sleeve and drive sleeve are coupled through the clutch. Conversely, when the dose dial sleeve and drive sleeve are in a de-coupled state, rotation of the dose dial sleeve with respect to the housing is permitted and rotation of the drive sleeve with respect to the housing is prevented. In the de-coupled state, axial movement of the drive sleeve transfers force in a longitudinal direction for actuation of a drug delivery device.
摘要翻译: 公开了一种适用于药物输送装置的驱动机构。 驱动机构可以与注射器型药物递送装置一起使用,例如允许用户设定递送剂量的那些。 驱动机构可以包括壳体,剂量拨号套筒和驱动套筒。 离合器构造成当剂量拨盘套筒和驱动套筒通过离合器联接时允许驱动套筒和剂量拨盘套筒相对于壳体旋转。 相反,当剂量拨号套筒和驱动套筒处于脱耦合状态时,允许剂量拨盘套筒相对于壳体的旋转,并且防止驱动套筒相对于壳体的旋转。 在脱耦合状态下,驱动套筒的轴向运动在纵向方向上传递力,用于致动药物输送装置。
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公开(公告)号:US07918833B2
公开(公告)日:2011-04-05
申请号:US11483546
申请日:2006-07-11
IPC分类号: A61M5/00
CPC分类号: A61M5/24 , A61M5/31528 , A61M5/31533 , A61M5/31535 , A61M5/31536 , A61M5/31541 , A61M5/31546 , A61M5/31551 , A61M5/3156 , A61M5/31563 , A61M5/31565 , A61M5/31568 , A61M5/3157 , A61M5/31575 , A61M5/31578 , A61M5/31585 , A61M5/31593 , A61M5/32 , A61M2005/2407 , A61M2005/3126 , A61M2205/581 , A61M2205/582
摘要: The present invention relates to injectors, such as pen-type injectors, that provide for administration of medicinal products from a multidose-cartridge and permit a user to set the delivery dose. The injector may include a housing, a piston rod adapted to operate through the housing, a dose dial sleeve located between the housing and the piston rod, and a drive sleeve located between the dose dial sleeve and the piston rod. The dose dial sleeve may have a helical thread of first lead and the drive sleeve may have a helical groove of second lead. The first lead of the helical thread and the second lead of the helical groove may be the same.
摘要翻译: 本发明涉及一种注射器,例如笔式注射器,其提供从多剂量药筒施用药用产品并允许使用者设定递送剂量。 注射器可以包括壳体,适于通过壳体操作的活塞杆,位于壳体和活塞杆之间的剂量拨号套筒,以及位于剂量盘套和活塞杆之间的驱动套筒。 剂量拨号套筒可以具有第一引线的螺旋螺纹,并且驱动套筒可以具有第二引线的螺旋槽。 螺旋形螺纹的第一引线和螺旋槽的第二引线可以相同。
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公开(公告)号:US20100233761A1
公开(公告)日:2010-09-16
申请号:US12721077
申请日:2010-03-10
IPC分类号: C07K2/00 , C22C38/00 , C22C24/00 , C22C23/00 , C22C27/04 , C22C22/00 , C22C9/00 , C22C18/00 , C01B35/02 , C01B25/00 , C01B21/00 , C01B31/20 , C01B7/01 , C01B19/02 , C01B17/00 , C12P21/00 , C12P7/64 , C12P7/04 , C12N13/00 , C12N1/12 , C07K14/00 , C07H3/02 , C08B37/00 , C07H3/04 , C09B5/00 , C07J1/00 , C08G63/48 , C07C229/00 , C07F9/06 , C07C35/00 , C07C31/22 , C07C9/00 , C07C15/24 , C07H3/06 , C07C11/02
CPC分类号: C12N1/06 , C12N1/12 , C12N13/00 , Y02E50/343
摘要: A method of fractionating biomass, by permeability conditioning biomass suspended in a pH adjusted solution of at least one water-based polar solvent to form a conditioned biomass, intimately contacting the pH adjusted solution with at least one non-polar solvent, partitioning to obtain an non-polar solvent solution and a polar biomass solution, and recovering cell and cell derived products from the non-polar solvent solution and polar biomass solution. Products recovered from the above method. A method of operating a renewable and sustainable plant for growing and processing algae.
摘要翻译: 通过将悬浮在至少一种水基极性溶剂的pH调节溶液中的生物质的渗透调节生物质分解生物质的方法,以形成调节的生物质,将pH调节的溶液与至少一种非极性溶剂紧密接触, 非极性溶剂溶液和极性生物质溶液,并从非极性溶剂溶液和极性生物质溶液中回收细胞和细胞衍生产物。 从上述方法回收产品。 一种用于生长和加工藻类的可再生和可持续植物的方法。
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公开(公告)号:US09296985B2
公开(公告)日:2016-03-29
申请号:US12963501
申请日:2010-12-08
CPC分类号: C12N1/06 , C12N1/12 , C12N13/00 , Y02E50/17 , Y02E50/343
摘要: A method of fractionating biomass, by permeability conditioning biomass suspended in a pH adjusted solution of at least one water-based polar solvent to form a conditioned biomass, intimately contacting the pH adjusted solution with at least one non-polar solvent, partitioning to obtain an non-polar solvent solution and a polar biomass solution, and recovering cell and cell derived products from the non-polar solvent solution and polar biomass solution. Products recovered from the above method. A method of operating a renewable and sustainable plant for growing and processing algae.
摘要翻译: 通过将悬浮在至少一种水基极性溶剂的pH调节溶液中的生物质的渗透调节生物质分解生物质的方法,以形成调节的生物质,将pH调节的溶液与至少一种非极性溶剂紧密接触, 非极性溶剂溶液和极性生物质溶液,并从非极性溶剂溶液和极性生物质溶液中回收细胞和细胞衍生产物。 从上述方法回收产品。 一种用于生长和加工藻类的可再生和可持续植物的方法。
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