公开(公告)号：US20210164926A1

公开(公告)日：2021-06-03

申请号：US17157292

申请日：2021-01-25

Applicant: Kaleido Biosciences, Inc.

Inventor： Christopher Matthew Liu ,  Anastasia Lioubomirov ,  John M. Geremia ,  Mitchell Antalek ,  Jonathan Lawrence ,  Tatyana Yatsunenko ,  Brian Meehan

IPC: G01N24/08 ,  C07H3/06 ,  C07H1/00

Abstract: Aspects of the disclosure relate to oligosaccharide compositions and methods of making the same. Also provided are methods of using oligosaccharide compositions as microbiome metabolic therapies for reducing ammonia levels and for the treatment of related diseases.

公开(公告)号：US20200093851A1

公开(公告)日：2020-03-26

申请号：US16395929

申请日：2019-04-26

Applicant: KALEIDO BIOSCIENCES, INC.

Inventor： Geoffrey A. von Maltzahn ,  Jared Silverman ,  Yvonne J. Yamanaka ,  John Miles Milwid ,  John M. Geremia

IPC: A61K31/716 ,  A61K31/165 ,  A61K31/706 ,  A61K31/366 ,  A61K31/11 ,  A61K31/365 ,  A61K31/34 ,  A61K31/09 ,  A61K31/353 ,  A61K31/7034 ,  A61K31/12 ,  A61K31/7048 ,  A61K31/715

Abstract: Preparations of glycan therapeutics, pharmaceutical compositions and medical foods thereof, optionally comprising micronutrients, polyphenols, prebiotics, probiotics, or other agents are provided and methods of making same. Also provided are methods of using said glycan therapeutics, e.g. for the modulation of human gastrointestinal microbiota and to treat dysbioses.

公开(公告)号：US09901595B2

公开(公告)日：2018-02-27

申请号：US15286382

申请日：2016-10-05

Applicant: KALEIDO BIOSCIENCES, INC.

Inventor： Geoffrey A. von Maltzahn ,  Jared Silverman ,  Yvonne J. Yamanaka ,  John Miles Milwid ,  John M. Geremia

IPC: A61K31/716

CPC classification number: A61K31/716 ,  A61K31/09 ,  A61K31/11 ,  A61K31/12 ,  A61K31/165 ,  A61K31/34 ,  A61K31/353 ,  A61K31/365 ,  A61K31/366 ,  A61K31/7034 ,  A61K31/7048 ,  A61K31/706 ,  A61K31/715 ,  A61K2035/115

Abstract: Preparations of glycan therapeutics, pharmaceutical compositions and medical foods thereof, optionally comprising micronutrients, polyphenols, prebiotics, probiotics, or other agents are provided and methods of making same. Also provided are methods of using said glycan therapeutics, e.g. for the modulation of human gastrointestinal microbiota and to treat dysbioses.

公开(公告)号：US20170151269A1

公开(公告)日：2017-06-01

申请号：US15385331

申请日：2016-12-20

Applicant: KALEIDO BIOSCIENCES, INC.

Inventor： Geoffrey A. von Maltzahn ,  Jared Silverman ,  Yvonne J. Yamanaka ,  John Miles Milwid ,  John M. Geremia

IPC: A61K31/702 ,  A61K35/741 ,  A61K45/06 ,  A61K31/7004 ,  A61K31/7016

CPC classification number: A61K31/702 ,  A23L33/10 ,  A23P10/00 ,  A23V2002/00 ,  A61K31/7004 ,  A61K31/7016 ,  A61K31/716 ,  A61K31/733 ,  A61K35/741 ,  A61K45/06 ,  A61K2035/115 ,  A61P1/00 ,  Y02A50/475 ,  Y02A50/481

Abstract: Preparations of glycan therapeutics, pharmaceutical compositions and medical foods thereof, optionally comprising micronutrients, polyphenols, prebiotics, probiotics, or other agents are provided and methods of making same. Also provided are methods of using said glycan therapeutics, e.g. for the modulation of human gastrointestinal microbiota and to treat dysbioses.

公开(公告)号：US20160213702A1

公开(公告)日：2016-07-28

申请号：US15017396

申请日：2016-02-05

Applicant: KALEIDO BIOSCIENCES, INC.

Inventor： Geoffrey A. von Maltzahn ,  Jared Silverman ,  Yvonne J. Yamanaka ,  John Miles Milwid ,  John M. Geremia

IPC: A61K31/715 ,  A61K31/12 ,  A61K31/7034 ,  A61K31/353 ,  A61K31/165 ,  A61K31/34 ,  A61K31/365 ,  A61K31/11 ,  A61K31/366 ,  A61K31/706 ,  A61K31/7048 ,  A61K31/09

CPC classification number: A61K31/716 ,  A61K31/09 ,  A61K31/11 ,  A61K31/12 ,  A61K31/165 ,  A61K31/34 ,  A61K31/353 ,  A61K31/365 ,  A61K31/366 ,  A61K31/7034 ,  A61K31/7048 ,  A61K31/706 ,  A61K31/715 ,  A61K2035/115

Abstract: Preparations of glycan therapeutics, pharmaceutical compositions and medical foods thereof, optionally comprising micronutrients, polyphenols, prebiotics, probiotics, or other agents are provided and methods of making same. Also provided are methods of using said glycan therapeutics, e.g. for the modulation of human gastrointestinal microbiota and to treat dysbioses.

Abstract translation: 提供了聚糖治疗剂，其药物组合物和医药食品，任选地包含微量营养素，多酚，益生元，益生菌或其它药剂的制备方法及其制备方法。 还提供了使用所述聚糖治疗剂的方法，例如， 用于调节人类胃肠道微生物群并治疗生殖器发育不良。