公开(公告)号：US09964664B2

公开(公告)日：2018-05-08

申请号：US14130932

申请日：2012-09-03

申请人： Peter Collins

发明人： Peter Collins

IPC分类号： G01V8/20 ,  B66B13/26

CPC分类号： G01V8/20 ,  B66B13/26

摘要： A method and sensing apparatus for elevators that detects an intrusion into a volume defined relative to a path across an opening. The sensing apparatus has a closure member for the opening that can be controllably displaced to define a gap in the opening. A first group of at least two emitters of electromagnetic signals located on either the closure member or a boundary member are directed into the volume and a second group of at least two receivers for electromagnetic signals located on the opposite side of the gap to the emitters. The method causes at least one of the emitters to emit a primary beam along a first axis into the volume, allows at least one of the receivers to receive a secondary beam of radiation, and enables one or more of the receivers to provide an output signal into the network.

公开(公告)号：US20140192692A1

公开(公告)日：2014-07-10

申请号：US13736924

申请日：2013-01-08

申请人： Jeremy Stark ,  Jonathan Tyson Williams ,  Peter Collins ,  Peter Andrew Rees Williams ,  Nick Jones

发明人： Jeremy Stark ,  Jonathan Tyson Williams ,  Peter Collins ,  Peter Andrew Rees Williams ,  Nick Jones

IPC分类号： H04W52/02

CPC分类号： H04W52/0209 ,  H04B1/406 ,  Y02D70/1262 ,  Y02D70/142 ,  Y02D70/144 ,  Y02D70/166 ,  Y02D70/40

摘要： A communication device comprising: a first radio capable of communicating according to a first protocol and having a set of operational modes; and a second radio capable of communicating according to a second protocol, the communication device being configured to, in dependence on one or more communications by the second radio in accordance with the second protocol, selecting one mode of operation for the first radio from the set of operational modes, wherein said one or more communications comprises: sending a first message; and a response or non-response to the first message.

摘要翻译： 一种通信设备，包括：能够根据第一协议进行通信并具有一组操作模式的第一无线电设备; 以及能够根据第二协议进行通信的第二无线电设备，所述通信设备被配置为根据所述第二无线电设备根据所述第二协议进行的一个或多个通信，从所述设备中选择所述第一无线电的一种操作模式 其中所述一个或多个通信包括：发送第一消息; 以及对第一条消息的响应或不响应。

公开(公告)号：US20070150356A1

公开(公告)日：2007-06-28

申请号：US11636481

申请日：2006-12-11

申请人： Christos Kapsambelis ,  Peter Collins ,  David Collins

发明人： Christos Kapsambelis ,  Peter Collins ,  David Collins

IPC分类号： G06Q20/00

CPC分类号： G06Q10/08 ,  G06Q20/208

摘要： A system and method for validating adherence of an UII identifier code to one of several prescribed DOD codes by means of a programmed series of tests. First the code is tested for a prescribed header and a last character message. If one or the other is not found, the process stops and an error message is displayed. Field separator characters are identified that divide the message into fields. If the header, end of message character, and field separator are found and tested successfully, the program proceeds, and searches for an identifier of one of the DOD prescribed semantic formats. The semantic format identifier is extracted and tested. If valid, the process proceeds. If not, an error message is displayed. In proceeding, each field is stored, and the data from each field is extracted in accordance with the format identifier that had been extracted.

摘要翻译： 一种系统和方法，用于通过程序化的一系列测试来验证UII标识符对几个规定的DOD代码之一的依从性。 首先，对代码进行规定的标题和最后一个字符消息的测试。 如果没有找到一个或另一个，则该过程停止，并显示错误消息。 识别字段分隔符，将消息划分为字段。 如果头文件，消息字符结尾和字段分隔符被成功发现和测试，则程序继续进行，并且搜索DOD规定的语义格式之一的标识符。 提取和测试语义格式标识符。 如果有效，则该过程继续进行。 如果没有，将显示错误消息。 在进行中，存储每个字段，并且根据提取的格式标识符提取来自每个字段的数据。

公开(公告)号：US20060057158A1

公开(公告)日：2006-03-16

申请号：US11097946

申请日：2005-03-31

申请人： Ursula Buchholz ,  Peter Collins ,  Brian Murphy ,  Stephen Whitehead ,  Christine Krempl

发明人： Ursula Buchholz ,  Peter Collins ,  Brian Murphy ,  Stephen Whitehead ,  Christine Krempl

IPC分类号： A61K39/12 ,  C07H21/04 ,  C12N7/00

CPC分类号： C12N7/00 ,  A61K39/00 ,  A61K39/12 ,  A61K39/155 ,  A61K2039/5254 ,  A61K2039/5256 ,  A61K2039/544 ,  C07K14/005 ,  C07K2319/00 ,  C12N15/86 ,  C12N2760/18522 ,  C12N2760/18534 ,  C12N2760/18543 ,  C12N2760/18561 ,  C12N2840/203

摘要： Chimeric human-bovine respiratory syncytial virus (RSV) are infectious and attenuated in humans and other mammals and useful in vaccine formulations for eliciting an anti-RSV immune response. Also provided are isolated polynucleotide molecules and vectors incorporating a chimeric RSV genome or antigenome which includes a partial or complete human or bovine RSV “background” genome or antigenome combined or integrated with one or more heterologous gene(s) or genome segment(s) of a different RSV strain. Chimeric human-bovine RSV of the invention include a partial or complete “background” RSV genome or antigenome derived from or patterned after a human or bovine RSV strain or subgroup virus combined with one or more heterologous gene(s) or genome segment(s) of a different RSV strain or subgroup virus to form the human-bovine chimeric RSV genome or antigenome. In preferred aspects of the invention, chimeric RSV incorporate a partial or complete bovine RSV background genome or antigenome combined with one or more heterologous gene(s) or genome segment(s) from a human RSV. Genes of interest include any of the NS1, NS2, N, P, M, SH, M2(ORF1), M2(ORF2), L, F or G genes or a genome segment including a protein or portion thereof. A variety of additional mutations and nucleotide modifications are provided within the human-bovine chimeric RSV of the invention to yield desired phenotypic and structural effects.

摘要翻译： 嵌合人 - 牛呼吸道合胞病毒（RSV）在人类和其他哺乳动物中具有感染性和减毒性，并且可用于引发抗RSV免疫应答的疫苗制剂中。 还提供了分离的多核苷酸分子和掺入嵌合RSV基因组或抗原组的载体，其包括部分或完整的人或牛RSV“背景”基因组或与一个或多个异源基因或基因组片段 不同的RSV菌株。 本发明的嵌合人类牛RSV包括部分或完整的“背景”RSV基因组或在与一个或多个异源基因或基因组片段组合的人或牛RSV病毒株或亚组病毒之后衍生或构图的部分或完整的“背景” 的不同RSV株或亚组病毒形成人 - 牛嵌合RSV基因组或抗原组。 在本发明的优选方面，嵌合RSV包含与来自人RSV的一个或多个异源基因或基因组片段组合的部分或完整的牛RSV背景基因组或反义基因组。 感兴趣的基因包括任何NS1，NS2，N，P，M，SH，M2（ORF1），M2（ORF2），L，F或G基因或包含蛋白质或其部分的基因组片段。 在本发明的人 - 牛嵌合RSV内提供了多种额外的突变和核苷酸修饰，以产生所需的表型和结构效果。

公开(公告)号：US20060018927A1

公开(公告)日：2006-01-26

申请号：US11054343

申请日：2005-02-08

申请人： Christine Krempl ,  Peter Collins ,  Brian Murphy ,  Ursula Buchholz ,  Stephen Whitehead

发明人： Christine Krempl ,  Peter Collins ,  Brian Murphy ,  Ursula Buchholz ,  Stephen Whitehead

IPC分类号： A61K39/155 ,  C12Q1/70 ,  C12N7/00

CPC分类号： C07K14/005 ,  A61K39/12 ,  A61K39/155 ,  A61K2039/5254 ,  A61K2039/5256 ,  A61K2039/543 ,  C12N7/00 ,  C12N15/86 ,  C12N2760/18522 ,  C12N2760/18534 ,  C12N2760/18543 ,  C12N2760/18561 ,  C12N2760/18622

摘要： Recombinant respiratory syncytial virus (RSV) having the position of genes shifted within the genome or antigenome of the recombinant virus are infectious and attenuated in humans and other mammals. Gene shifted RSV are constructed by insertion, deletion or rearrangement of genes or genome segments within the recombinant genome or antigenome and are useful in vaccine formulations for eliciting an anti-RSV immune response. Also provided are isolated polynucleotide molecules and vectors incorporating a recombinant RSV genome or antigenome wherein a gene or gene segment is shifted to a more promoter-proximal or promoter-distal position within the genome or antigenome compared to a wild type position of the gene in the RSV gene map. Shifting the position of genes in this manner provides for a selected increase or decrease in expression of the gene, depending on the nature and degree of the positional shift. In one embodiment, RSV glycoproteins are upregulated by shifting one or more glycoprotein-encoding genes to a more promoter-proximal position. Genes of interest for manipulation to create gene position-shifted RSV include any of the NS1, NS2, N, P, M, SH, M2(ORF1), M2(ORF2), L, F or G genes or a genome segment that may be part of a gene or extragenic. A variety of additional mutations and nucleotide modifications are provided within the gene position-shifted RSV of the invention to yield desired phenotypic and structural effects.

公开(公告)号：US20050220767A1

公开(公告)日：2005-10-06

申请号：US10917984

申请日：2004-08-11

申请人： Peter Collins ,  Alexander Bukreyev ,  Brian Murphy ,  Stephen Whitehead

发明人： Peter Collins ,  Alexander Bukreyev ,  Brian Murphy ,  Stephen Whitehead

IPC分类号： C12N15/09 ,  A61K9/12 ,  A61K35/76 ,  A61K39/00 ,  A61K39/155 ,  A61K48/00 ,  A61P11/00 ,  A61P11/06 ,  A61P31/14 ,  A61P37/04 ,  C07K14/54 ,  C12N7/00 ,  C12N7/04 ,  C12N15/86 ,  A61K39/12

CPC分类号： C07K14/54 ,  A61K39/00 ,  A61K48/00 ,  C07K2319/00 ,  C12N15/86 ,  C12N2760/18543 ,  C12N2840/20

摘要： Recombinant respiratory syncytial virus (RSV) are provided which express one or more immune modulatory molecules. The recombinant virus is modified by addition or substitution of a polynucleotide sequence encoding the immune modulatory molecule, which is preferably a cytokine. Introduction of the cytokine increase, decrease, or otherwise enhances aspects of viral biology and/or host immune responses to RSV to facilitate vaccine use of the virus. Cytokines for use within the invention include but are not limited to interleukin 2 (IL-2), interleukin 4 (IL-4), interleukin 5 (IL-5), interleukin 6 (IL-6), or interleukin 18 (IL-18), tumor necrosis factor (TNF) alpha, interferon gamma (IFN), and granulocyte-macrophage colony stimulating factor (GM-CSF). The polynucleotide or immune modulatory molecule is preferably added or substituted into the recombinant viral genome or antigenome, typically at an intergenic or other non-coding site, as a separate gene but may be otherwise expressed, for example as a fusion protein.

摘要翻译： 提供重组呼吸道合胞病毒（RSV），其表达一种或多种免疫调节分子。 通过添加或取代编码免疫调节分子的多核苷酸序列来修饰重组病毒，所述多核苷酸序列优选是细胞因子。 引入细胞因子增加，减少或以其他方式增强病毒生物学和/或宿主对RSV的免疫应答的方面以促进病毒的疫苗使用。 用于本发明的细胞因子包括但不限于白介素2（IL-2），白细胞介素4（IL-4），白细胞介素5（IL-5），白介素6（IL-6）或白细胞介素18（IL- 18），肿瘤坏死因子（TNF）α，干扰素γ（IFN）和粒细胞巨噬细胞集落刺激因子（GM-CSF）。 多核苷酸或免疫调节分子优选地作为单独的基因加入或取代到重组病毒基因组或反向原核基因组中，通常在基因间或其他非编码位点，但可另外表达为例如融合蛋白。

公开(公告)号：USRE36701E

公开(公告)日：2000-05-16

申请号：US69397

申请日：1998-04-29

申请人： Peter Collins

发明人： Peter Collins

IPC分类号： A61K31/56

摘要： Use of 17.beta.-oestradiol in the treatment of coronary heart disease.

摘要翻译： 使用17β-雌二醇治疗冠心病。

公开(公告)号：US4565999A

公开(公告)日：1986-01-21

申请号：US466074

申请日：1983-04-01

申请人： Allen King ,  Peter Collins ,  Jay Goldman

发明人： Allen King ,  Peter Collins ,  Jay Goldman

IPC分类号： G06F3/00 ,  G06F3/01 ,  G06F3/023 ,  G06F3/033 ,  G06F3/042 ,  G09G1/00

CPC分类号： G06F3/012 ,  G06F3/0308 ,  G06F3/033 ,  G06F3/03545 ,  G06F3/04892

摘要： A cursor control system for use with a data terminal having a display consists of a radiation source and associated radiation sensor. Either the source or sensor is fixed with respect to the display while the other is moveable and may be fixed to the user's head. The system translates the motion of the user's head into a directional signal for controlling cursor position on the screen.

摘要翻译： 与具有显示器的数据终端一起使用的光标控制系统由辐射源和相关联的辐射传感器组成。 源或传感器相对于显示器固定，而另一个可移动，并且可以固定到用户的头部。 该系统将用户头部的运动转换成用于控制屏幕上光标位置的方向信号。

公开(公告)号：US08136262B2

公开(公告)日：2012-03-20

申请号：US12147725

申请日：2008-06-27

申请人： Peter Collins

发明人： Peter Collins

IPC分类号： F26B19/00

CPC分类号： A47K10/48

摘要： A drier information system is provided including display means relating to a given region of the system which means serves, at least while a drying cycle is in operation, to provide a visual display indicating at least one of the following parameters: the extent of the region; a boundary of the region; direction or example of manipulation of a pair of hands or other article while in the region to provide for a preferred drying sequence. The visual display can represent the parameters as a two dimensional array within or adjacent the region. Alternatively the visual display can represent the parameters as a virtual or actual three dimensional array within or adjacent the region.

摘要翻译： 提供了一种干燥的信息系统，其包括与系统的给定区域有关的显示装置，该装置至少在干燥循环正在运行时提供指示下列参数中的至少一个的视觉显示：该区域的程度 ; 该地区的边界; 在该区域中操作一对手或其它制品的方向或示例，以提供优选的干燥顺序。 视觉显示可以将参数表示为区域内或附近的二维阵列。 或者，视觉显示可以将参数表示为区域内或邻近区域中的虚拟或实际三维阵列。

公开(公告)号：US20070184678A1

公开(公告)日：2007-08-09

申请号：US11649472

申请日：2007-01-04

申请人： Nik Codling ,  Peter Collins

发明人： Nik Codling ,  Peter Collins

IPC分类号： H01R12/00

CPC分类号： F16B21/10 ,  H01R13/5219

摘要： A Connector comprising a rigid base member covered by a resilient layer base member further comprising a contact member formed of a head portion and a stem portion, whereby the head portion is arranged to project from the outer surface of the resilient layer and the stem portion is located within the base member and the resilient layer, the stem portion being held in position by a retaining member. Preferably, the resilient layer is formed of an elsatomer material which extends around the periphery of the connector.

摘要翻译： 一种连接器，包括由弹性层基底构件覆盖的刚性基部构件，还包括由头部和杆部构成的接触构件，由此所述头部布置成从所述弹性层的外表面突出并且所述杆部分是 位于基部构件和弹性层内，杆部分通过保持构件保持就位。 优选地，弹性层由围绕连接器的周边延伸的消声器材料形成。