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71 条记录 (耗时 0.048 秒)

    Electromagnetic rotating armature relay
    21.
    发明授权
    Electromagnetic rotating armature relay 失效
    电磁旋转电枢继电器

    公开(公告)号：US4539540A

    公开(公告)日：1985-09-03

    申请号：US495648

    申请日：1983-05-18

    申请人： Rolf-Dieter Kimpel ,  Heinz Stadler ,  Alfred Heinzl

    发明人： Rolf-Dieter Kimpel ,  Heinz Stadler ,  Alfred Heinzl

    IPC分类号： H01H50/18 ,  H01H50/54 ,  H01H50/58

    CPC分类号： H01H50/548

    摘要： The rotating armature relay exhibits one or two ferromagnetic bars which are provided with an insulating covering in their central area. Contact springs are secured in the insulation covering, the contacting, free ends of said contact springs respectively interacting with cooperating contact elements anchored in a base body. As a result, a slide-free and, thus, low-friction actuation derives as, however, does relatively high friction at the contact locations, whereby contact impacts are suppressed and foreign layers are abraded from the contact surfaces.

    摘要翻译： 旋转电枢继电器显示一个或两个铁磁条，它们在其中心区域设有绝缘覆盖物。 接触弹簧固定在绝缘覆盖层中，所述接触弹簧的接触自由端分别与锚定在基体中的协作接触元件相互作用。 因此，无滑动且因此低摩擦力的致动来源于接触位置处的相对较高的摩擦力，从而抑制接触冲击并且从接触表面磨蚀外来层。

    Device for conveying and dispensing liquid media
    22.
    发明授权
    Device for conveying and dispensing liquid media 失效
    用于输送和分配液体介质的装置

    公开(公告)号：US4363426A

    公开(公告)日：1982-12-14

    申请号：US194335

    申请日：1980-10-06

    申请人： Alfred Heinzl ,  Heinz Stadler

    发明人： Alfred Heinzl ,  Heinz Stadler

    IPC分类号： F04B13/00 ,  B01F15/04 ,  B29B7/60 ,  B67D7/64 ,  F04B13/02 ,  F04B53/12 ,  G01F11/04 ,  B67D5/46 ,  B67D5/52

    CPC分类号： G01F11/04 ,  B01F15/0237 ,  B01F15/0462 ,  B29B7/603 ,  F04B13/02 ,  F04B53/129

    摘要： A device for conveying and dispensing liquid media such as casting resin has at least one piston pump having a cylinder chamber which forms a seal for a piston therein which is connected via an input opening to a feed container for receiving a supply of liquid therefrom. The cylinder chamber has an output opening and the piston is tubular in form having wall perforations in the region of the input opening for admitting the liquid to the interior of the piston and has a valve at a discharging end thereof for exit of the liquid from the piston. A seal is thus formed by which the piston operates entirely surrounded by the liquid medium to be dispensed and external seals between the piston and the atmosphere are eliminated.

    摘要翻译： 用于输送和分配诸如铸塑树脂的液体介质的装置具有至少一个活塞泵，其具有气缸室，该气缸室形成用于其中的活塞的密封件，其经由输入开口连接到用于从其接收液体供应的进料容器。 气缸室具有输出开口，并且活塞为管状形式，在输入开口的区域具有壁穿孔，用于将液体引入活塞的内部，并且在其排出端具有阀，用于将液体从 活塞。 因此形成密封件，通过该密封件，活塞完全由要分配的液体介质包围，并且消除了活塞和大气之间的外部密封。

    SUBSTITUTED IMIDAZO[1,5-A][1,2,4]TRIAZOLO[1,5-D][1,4]BENZODIAZEPINE DERIVATIVES
    25.
    发明申请
    SUBSTITUTED IMIDAZO[1,5-A][1,2,4]TRIAZOLO[1,5-D][1,4]BENZODIAZEPINE DERIVATIVES 失效
    取代的咪唑并[1,5-A] [1,2,4]三唑并[1,5-D] [1,4]苯并恶嗪衍生物

    公开(公告)号：US20100075954A1

    公开(公告)日：2010-03-25

    申请号：US12618802

    申请日：2009-11-16

    申请人： Henner Knust ,  Heinz Stadler ,  Andrew William Thomas

    发明人： Henner Knust ,  Heinz Stadler ,  Andrew William Thomas

    IPC分类号： A61K31/551 ,  C07D243/10 ,  A61P25/28

    CPC分类号： A61K31/5517 ,  C07D487/14

    摘要： The present invention is concerned with a method of treating Alzheimer's disease by administering a therapeutically effective amount of a substituted imidazo[1,5-a][1,2,4]triazolo[1,5-d][1,4]benzodiazepine of formula I wherein R1, R2, and R3 are as defined herein, and their pharmaceutically acceptable acid addition salts. The invention also provides novel compounds of formula I-A and pharmaceutical compositions containing them.

    摘要翻译： 本发明涉及通过施用治疗有效量的取代咪唑并[1,5-a] [1,2,4]三唑并[1,5-d] [1,4]苯并二氮杂治疗阿尔茨海默病的方法 其中R 1，R 2和R 3如本文所定义，并且其药学上可接受的酸加成盐。 本发明还提供新颖的式I-A化合物和含有它们的药物组合物。

    Transport system for small components
    27.
    发明授权
    Transport system for small components 有权
    小零件运输系统

    公开(公告)号：US07306092B1

    公开(公告)日：2007-12-11

    申请号：US09857353

    申请日：1999-12-01

    申请人： Alfred Heinzl ,  Heinz Stadler

    发明人： Alfred Heinzl ,  Heinz Stadler

    IPC分类号： B65G29/00

    CPC分类号： B65G47/44

    摘要： A system for transporting small components, generally electrical components, arranged in a row comprising an arbitrary number of chain links. The components are accommodated within a cavity present in the chain links. The cavity is defined by at least two walls, at least one of which must be rigid, while the wall located opposite thereof is a resilient wall.

    摘要翻译： 一种用于输送排列成包括任意数量的链节的行的小部件（通常为电气部件）的系统。 部件容纳在链节中存在的空腔内。 空腔由至少两个壁限定，其中至少一个必须是刚性的，而与其相对的壁是弹性壁。

    2,4,5,-trisubstituted pyrimidine derivatives
    28.
    发明授权
    2,4,5,-trisubstituted pyrimidine derivatives 失效
    2,4,5， - 三取代的嘧啶衍生物

    公开(公告)号：US06787539B2

    公开(公告)日：2004-09-07

    申请号：US09977586

    申请日：2001-10-15

    申请人： Heinz Stadler

    发明人： Heinz Stadler

    IPC分类号： C07D23924

    CPC分类号： C07D239/47 ,  C07D239/52 ,  C07D239/56 ,  C07D401/04

    摘要： The invention relates to compounds of the formula wherein R1 is lower alkyl, lower alkoxy, pyridinyl, pyrimidinyl, phenyl, —S-lower alkyl, —S(O)2-lower alkyl, —N(R)—(CH2)n—N(R)2, —O—(CH2)n—N(R)2, —N(R)2, or a cyclic tertiary amine of the group which may contain one additional heteroatom, selected from N, O or S, and wherein this group may be connected with the pyrimidine ring via the linker —O(CH2)n—; R2 is hydrogen, lower alkyl, lower alkoxy, halogen or trifluoromethyl; R3/R3′ is, independently from each other, hydrogen or lower alkyl; R4 is independently from each other halogen, trifluoromethyl or lower alkoxy; R5 is hydrogen or lower alkyl; R is, independently from each other, hydrogen or lower alkyl; X is —C(O)N(R)— or —N(R)C(O)—; Y is —O—, —S—, —SO2—, - or —N(R)—; n is 1,2,3 or 4; and m is 0,1 or 2; or a pharmaceutically acceptable acid addition salt thereof. The compound of the invention has affintity to the NK1 receptor and is therefore suitable in the treatment of diseases related to this recepor.

    摘要翻译： 本发明涉及式I的化合物，其中R 1为低级烷基，低级烷氧基，吡啶基，嘧啶基，苯基，-S-低级烷基，-S（O）2 - 低级烷基，-N（R） - （CH 2）n N （R）2，-O-（CH 2）n N（R）2，-N（R）2）或可以含有一个选自N，O或S的另外的杂原子的基团的环状叔胺， 可以通过连接基-O（CH 2）n - ; R 2是氢，低级烷基，低级烷氧基，卤素或三氟甲基与嘧啶环连接; R 3 / R 3'各自独立地为 R 4彼此独立地为卤素，三氟甲基或低级烷氧基; R 5为氢或低级烷基; R为彼此独立地为氢或低级烷基; X为-C （O）N（R） - 或-N（R）C（O） - ; Y是-O - ， - S-，-SO 2 - ， - 或-N（R） - ; n是1,2,3 或4; 和m为0,1或2;或其药学上可接受的酸加成盐。 本发明化合物对NK1受体具有亲和性，因此适用于治疗与该受体有关的疾病。

    3-phenyl-pyridine-derivatives
    30.
    发明授权
    3-phenyl-pyridine-derivatives 失效
    3-苯基 - 吡啶衍生物

    公开(公告)号：US06225316B1

    公开(公告)日：2001-05-01

    申请号：US09505359

    申请日：2000-02-16

    申请人： Michael Bös ,  Guido Galley ,  Thierry Godel ,  Torsten Hoffmann ,  Walter Hunkeler ,  Patrick Schnider ,  Heinz Stadler

    发明人： Michael Bös ,  Guido Galley ,  Thierry Godel ,  Torsten Hoffmann ,  Walter Hunkeler ,  Patrick Schnider ,  Heinz Stadler

    IPC分类号： A61K3150

    CPC分类号： C07D213/75 ,  C07D213/38 ,  C07D213/81

    摘要： The invention relates to compounds of the formula wherein R is hydrogen, lower alkyl, lower alkoxy, halogen or trifluoromethyl; R1 is hydrogen or halogen; or R and R1 may be together —CH═CH—CH═CH—; R2 is hydrogen, halogen, trifluoromethyl, lower alkoxy or cyano; R3 is hydrogen, lower alkyl or form a cycloalkyl group; R4 is hydrogen, —N(R5)2, —N(R5)S(O)2-lower alkyl, —N(R5)C(O)R5 or a cyclic tertiary amine of the group R5 is, independently from each other, hydrogen, C3-6-cycloalkyl, benzyl or lower alkyl; R6 is hydrogen, hydroxy, lower alkyl, —N(R5)CO-lower alkyl, hydroxy-lower alkyl, cyano, —CHO or a 5- or 6 membered heterocyclic group, optionally bonded via an alkylene group, X is —C(O)N(R5)—, —(CH2)mO—, —(CH2)mN(R5)—, —N(R5)C(O)—, or —N(R5)(CH2)m—; n is 0-4; and m is 1 or 2; and to pharmaceutically acceptable acid addition salts thereof. It has been shown that the above mentioned compounds have a good affinity to the NK-1 receptor.

    摘要翻译： 本发明涉及式Ⅳ的化合物，其中R是氢，低级烷基，低级烷氧基，卤素或三氟甲基; R 1是氢或卤素; 或R 1可以是-CH = CH-CH = CH-; R 2是氢，卤素，三氟甲基，低级烷氧基或氰基; R 3是氢，低级烷基或形成环烷基; R 4是氢，-N（R 5） 2，-N（R 5）S（O）2-低级烷基，-N（R 5）C（O）R 5或基团R 5的环状叔胺彼此独立地为氢，C 3-6 - 环烷基，苄基 或低级烷基; R6是氢，羟基，低级烷基，-N（R5）CO-低级烷基，羟基 - 低级烷基，氰基，-CHO或5-或6-元杂环基，任选地通过亚烷基键合，X 是（C） - （CH 2）m O - ， - （CH 2）m N（R 5） - ， - N（R 5）C（O） - 或-N（R 5） - ; n为0-4; 和m为1或2;以及其药学上可接受的酸加成盐。已经显示上述化合物对NK-1受体具有良好的亲和力。