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公开(公告)号：US20190290910A1
公开(公告)日：2019-09-26
申请号：US16361970
申请日：2019-03-22
Applicant: Medtronic, Inc.
Inventor： Zhongping Yang , Thomas A. Anderson , Brian P. Colin , William J. Clemens , Subham Ghosh , Jeffrey M. Gillberg , Maurice T. I. Verbeek , Toine Camps , Lilian Kornet , Berthold Stegemann , Jean Rutten
Abstract: VfA cardiac therapy uses an implantable medical device or system. The implantable medical device includes a tissue-piercing electrode implanted in the basal and/or septal region of the left ventricular myocardium of the patient's heart from the triangle of Koch region of the right atrium through the right atrial endocardium and central fibrous body. The device may include a right atrial electrode, a right atrial motion detector, or both. The device may be implanted completely within the patient's heart or may use one or more leads to implant electrodes in the patient's heart. The device may be used to provide cardiac therapy, including single or multiple chamber pacing, atrioventricular synchronous pacing, asynchronous pacing, triggered pacing, cardiac resynchronization pacing, or tachycardia-related therapy. A separate medical device may be used to provide some functionality for cardiac therapy, such as sensing, pacing, or shock therapy.
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公开(公告)号：US10080900B2
公开(公告)日：2018-09-25
申请号：US15140585
申请日：2016-04-28
Applicant: Medtronic, Inc.
Inventor： Subham Ghosh , Stefan Kracker , Todd J Sheldon
CPC classification number: A61N1/36585 , A61B5/026 , A61B5/1107 , A61B5/4836 , A61N1/0573 , A61N1/36571 , A61N1/36578 , A61N1/3684 , A61N1/37205 , A61N1/3756
Abstract: An intracardiac ventricular pacemaker is configured to detect an atrial mechanical event from a motion sensor signal received by an atrial event detector circuit of the pacemaker. The motion sensor signal is responsive the motion of blood flowing in the ventricle. A pacing pulse is scheduled at an expiration of a pacing interval set by a pace timing circuit in response to detecting the atrial mechanical event. An atrial-synchronized ventricular pacing pulse is delivered upon expiration of the pacing interval.
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公开(公告)号：US09962097B2
公开(公告)日：2018-05-08
申请号：US15345225
申请日：2016-11-07
Applicant: Medtronic, Inc.
Inventor： Subham Ghosh , Jeffrey M. Gillberg , Robert W. Stadler
IPC: A61B5/04 , A61B5/0452 , A61B5/05 , A61B5/02 , A61B5/0402 , A61B5/0408 , A61N1/04 , A61N1/362 , A61N1/368 , A61B5/00 , A61B5/044
CPC classification number: A61B5/04012 , A61B5/02 , A61B5/0402 , A61B5/04085 , A61B5/044 , A61B5/0452 , A61B5/05 , A61B5/742 , A61N1/0476 , A61N1/0484 , A61N1/3627 , A61N1/3682 , A61N1/3684
Abstract: Techniques for evaluating cardiac electrical dyssynchrony are described. In some examples, an activation time is determined for each of a plurality of torso-surface potential signals. The dispersion or sequence of these activation times may be analyzed or presented to provide variety of indications of the electrical dyssynchrony of the heart of the patient. In some examples, the locations of the electrodes of the set of electrodes, and thus the locations at which the torso-surface potential signals were sensed, may be projected on the surface of a model torso that includes a model heart. The inverse problem of electrocardiography may be solved to determine electrical activation times for regions of the model heart based on the torso-surface potential signals sensed from the patient.
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公开(公告)号：US09956416B2
公开(公告)日：2018-05-01
申请号：US13706472
申请日：2012-12-06
Applicant: Medtronic, Inc.
Inventor： Subham Ghosh , Robert W Stadler
CPC classification number: A61N1/3706 , A61N1/3622 , A61N1/3627 , A61N1/3682 , A61N1/3937
Abstract: Methods and/or devices may be configured to track effectiveness of pacing therapy by monitoring activation times over time, e.g., between pacing stimulus and electrical activity resulting from the pacing stimulus. Generally, the methods and/or devices may determine whether the delivered pacing therapy was effective based on the measured activation times.
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25.发明申请公开(公告)号：US20170274214A1
公开(公告)日：2017-09-28
申请号：US15618311
申请日：2017-06-09
Applicant: Medtronic, Inc.
Inventor： Richard M.T. Lu , Subham Ghosh , Robert W. Stadler
CPC classification number: A61N1/371 , A61B5/046 , A61N1/3622 , A61N1/3624 , A61N1/3684 , A61N1/3716
Abstract: The present disclosure pertains to cardiac pacing methods and systems, and, more particularly, to cardiac resynchronization therapy (CRT). In particular, the present disclosure pertains to determining whether a patient is experiencing atrial fibrillation (AF). If the patient is experiencing AF, the efficacy of CRT is determined. A signal is sensed in response to a ventricular pacing stimulus. Through signal processing, a number of features are parsed from the signal and a determination is made as to whether the ventricular pacing stimulus evoked a response from the ventricle.
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Patent Agency Ranking
公开(公告)号：US20170274213A1
公开(公告)日：2017-09-28
申请号：US15140585
申请日：2016-04-28
Applicant: Medtronic, Inc.
Inventor： Subham Ghosh , Stefan Kracker , Todd J Sheldon
CPC classification number: A61N1/36585 , A61B5/026 , A61B5/1107 , A61B5/4836 , A61N1/0573 , A61N1/36571 , A61N1/36578 , A61N1/3684 , A61N1/37205 , A61N1/3756
Abstract: An intracardiac ventricular pacemaker is configured to detect an atrial mechanical event from a motion sensor signal received by an atrial event detector circuit of the pacemaker. The motion sensor signal is responsive the motion of blood flowing in the ventricle. A pacing pulse is scheduled at an expiration of a pacing interval set by a pace timing circuit in response to detecting the atrial mechanical event. An atrial-synchronized ventricular pacing pulse is delivered upon expiration of the pacing interval.
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27.发明申请公开(公告)号：US20170246460A1
公开(公告)日：2017-08-31
申请号：US15142118
申请日：2016-04-29
Applicant: Medtronic, Inc.
Inventor： Subham Ghosh
Abstract: Methods and systems of evaluating cardiac pacing in candidate patients for cardiac resynchronization therapy and cardiac resynchronization therapy patients are disclosed. The methods and systems disclosed allow treatments to be personalized to patients by measuring the extent of tissue capture from cardiac pacing under various therapy parameter conditions. Systems and methods of optimizing right ventricle only cardiac pacing are also disclosed.
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公开(公告)号：US09700729B2
公开(公告)日：2017-07-11
申请号：US14880840
申请日：2015-10-12
Applicant: Medtronic, Inc.
Inventor： Subham Ghosh , Robert W Stadler
IPC: A61N1/368 , A61N1/37 , A61B5/0452
CPC classification number: A61N1/3686 , A61B5/0452 , A61N1/3684 , A61N1/3702 , A61N1/3706
Abstract: Generally, the disclosure is directed one or more methods or systems of cardiac pacing employing a right ventricular electrode and a plurality of left ventricular electrodes. Pacing using the right ventricular electrode and a first one of the left ventricular electrodes and measuring activation times at other ones of the left ventricular electrodes. Pacing using the right ventricular electrode and a second one of the ventricular electrodes and measuring activation times at other ones of the left ventricular electrodes. Computing a first degree of resynchronization based on a sum of differences of activation times and corresponding activation times. Pacing using the right ventricular electrode and a second one of the ventricular electrodes and measuring activation times at other ones of the left ventricular electrodes. Computing a second degree of resynchronization based on the sum of differences of activation times and corresponding activation times. Selecting one of the left ventricular electrodes for delivery of subsequent pacing pulses based on the computed degrees of resynchronization.
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29.发明授权公开(公告)号：US09700728B2
公开(公告)日：2017-07-11
申请号：US15056366
申请日：2016-02-29
Applicant: Medtronic, Inc.
Inventor： Subham Ghosh
IPC: A61N1/36 , A61N1/365 , A61N1/362 , A61N1/372 , A61B5/0408
CPC classification number: A61N1/36585 , A61B5/04085 , A61N1/36185 , A61N1/362 , A61N1/372
Abstract: A system and method select a pacing site for a cardiac pacing therapy. A change from a baseline mechanical activity is extracted from a signal of mechanical heart activity during pacing at each one of multiple pacing sites along a heart chamber. A change from a baseline electrical activity is extracted from a signal of electrical heart activity during pacing at each of the of pacing sites. The pacing sites are sorted in a first order based upon the changes in mechanical heart activity and in a second order based upon the changes in electrical heart activity. A pacing site is selected from the multiple pacing sites as a common pacing site between the first order and the second order.
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30.发明申请DELIVERY OF BI-VENTRICULAR PACING THERAPY IN A CARDIAC MEDICAL DEVICE AND MEDICAL DEVICE SYSTEM 有权在心脏医疗设备和医疗设备系统中提供双向腹膜治疗公开(公告)号：US20170028203A1
公开(公告)日：2017-02-02
申请号：US14919912
申请日：2015-10-22
Applicant: Medtronic, Inc.
Inventor： Subham Ghosh
CPC classification number: A61N1/3684 , A61B5/042 , A61B5/04525 , A61B5/0456 , A61B5/0468 , A61B5/4836 , A61N1/056 , A61N1/3627 , A61N1/36514 , A61N1/3682 , A61N1/3688 , A61N1/371 , A61N1/3712 , A61N1/37223 , A61N1/3756 , A61N1/3956
Abstract: An implantable medical device and medical device system for delivering a bi-ventricular pacing therapy that includes a plurality of electrodes to sense a cardiac signal, an emitting device to emit a trigger signal to control delivery of the bi-ventricular pacing, and a processor configured to compare the sensed cardiac signal associated with the delivered bi-ventricular pacing to at least one of an intrinsic beat template and an RV template associated with a morphology of RV-only pacing therapy, determine whether an offset interval associated with the bi-ventricular pacing therapy is set to a maximum offset interval level in response to the comparing, adjust the offset interval in response to the offset interval not being set to the maximum offset interval level, and generate the trigger signal to be emitted by the emitting device to subsequently deliver the bi-ventricular pacing therapy having the adjusted offset interval.
Abstract translation: 一种用于递送包括多个电极以感测心脏信号的双心室起搏疗法的可植入医疗装置和医疗装置系统，发射装置以发射触发信号以控制双心室起搏的传递，以及配置的处理器 将与传送的双心室起搏相关联的感测到的心脏信号与仅RV起搏治疗的形态相关联的内在搏动模板和RV模板中的至少一个来确定与双心室起搏相关联的偏移间隔 响应于比较将治疗设置为最大偏移间隔电平，响应于未被设置为最大偏移间隔电平的偏移间隔来调整偏移间隔，并且生成由发射装置发射以随后传送的触发信号 双心室起搏治疗具有调整的偏移间隔。
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