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公开(公告)号：US20240053364A1
公开(公告)日：2024-02-15
申请号：US18126546
申请日：2023-03-27
Applicant: Meso Scale Technologies, LLC.
Inventor： Eli N. Glezer , John Kenten , Sudeep Kumar , Galina Nikolenko
IPC: G01N33/68
CPC classification number: G01N33/6893 , G01N2800/347 , G01N2800/52 , G01N2333/70578 , G01N2333/4706 , G01N2333/4727 , G01N2333/70596 , G01N2333/8146
Abstract: The present invention relates to methods of diagnosing a kidney disorder in a patient, as well as methods of monitoring the progression of a kidney disorder and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.
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公开(公告)号：US20230038393A1
公开(公告)日：2023-02-09
申请号：US17720956
申请日：2022-04-14
Applicant: Meso Scale Technologies, LLC.
Inventor： Jeff D. Debad , Eli N. Glezer , Sudeep M. Kumar
IPC: G01N33/68
Abstract: Disclosed are methods for conducting diagnostic tests for the detection of the inflammatory bowel diseases, such as Crohn’s disease and ulcerative colitis. Also described are methods for monitoring a patient by administering tests of the present invention. Also described are methods for monitoring patient’s treatment by administering tests of the present invention. Also described are methods for evaluating the effectiveness of a drug or a drug candidate by administering tests of the present invention to samples from patients, animal models, and cell cultures treated with a drug or a drug candidate. Also disclosed are methods for determining the usefulness of analytes, e.g. cytokines, for acting as diagnostic and monitoring markers for inflammatory bowel disease in the various methods of the invention.
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公开(公告)号：US11467161B2
公开(公告)日：2022-10-11
申请号：US15386346
申请日：2016-12-21
Applicant: Meso Scale Technologies, LLC.
Inventor： Simone Barbero , Eli N. Glezer , Anu Mathew , Mingyue Wang
IPC: G01N33/574 , A61K31/44 , A61K31/404 , C12Q1/48
Abstract: The present invention relates to methods of diagnosing a kidney disorder in a patient, as well as methods of monitoring the progression of a kidney disorder and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.
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公开(公告)号：US20220215905A1
公开(公告)日：2022-07-07
申请号：US17701879
申请日：2022-03-23
Applicant: Meso Scale Technologies, LLC.
Inventor： Charles M. Clinton , Xinri Cong , Eli N. Glezer , Sudeep Kumar , Carl Stevens , Michael Vock , Jon S. Willoughby
IPC: G16C20/20 , G01N35/00 , G01N33/543 , B01L3/00 , G16H10/40
Abstract: The present invention relates to methods, devices and systems for associating assay information with an assay consumable used in a biological assay. Provided are assay systems and associated consumables, wherein the assay system includes a reader adapted to read/erase/write information from/to an assay consumable identifier associated with the assay consumable. Various types of assay information are described, as well as methods of using such information in the conduct of an assay by an assay system.
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公开(公告)号：US11242570B2
公开(公告)日：2022-02-08
申请号：US15696953
申请日：2017-09-06
Applicant: Meso Scale Technologies, LLC.
Inventor： Eli N. Glezer , George Sigal
IPC: C12Q1/70 , C12Q1/6813 , G01N33/542 , G01N33/543 , C12Q1/6834
Abstract: The present invention is directed to methods for reducing cross-reactivity between species employed in multiplexed immunoassays.
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Patent Agency Ranking
公开(公告)号：US20220033918A1
公开(公告)日：2022-02-03
申请号：US17504937
申请日：2021-10-19
Applicant: Meso Scale Technologies, LLC.
Inventor： Eli N. Glezer , George Sigal
IPC: C12Q1/70 , C12Q1/6813 , G01N33/542 , G01N33/543 , C12Q1/6834
Abstract: The present invention is directed to methods for reducing cross-reactivity between species employed in multiplexed immunoassays.
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公开(公告)号：US20210025896A1
公开(公告)日：2021-01-28
申请号：US17061095
申请日：2020-10-01
Applicant: Meso Scale Technologies, LLC
Inventor： Charles M. CLINTON , Eli N. Glezer , Bandele JEFFREY-COKER , Sandor L. KOVACS , Sudeep M. KUMAR , George SIGAL , Carl STEVENS , Michael Vock
Abstract: We describe apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation. They are particularly well suited for conducting automated sampling, sample preparation, and analysis in a multi-well plate assay format. For example, they may be used for automated analysis of particulates in air and/or liquid samples derived therefrom in environmental monitoring.
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公开(公告)号：US10814327B2
公开(公告)日：2020-10-27
申请号：US15646578
申请日：2017-07-11
Applicant: Meso Scale Technologies, LLC.
Inventor： Eli N. Glezer , Stephen Higgins , Sandor Kovacs , Sudeep Kumar , Kenneth Page , Kristian Roth , George Sigal
Abstract: Assay cartridges are described that have purification, reaction, and detection zones and other fluidic components which can include sample chambers, waste chambers, conduits, vents, reagent chambers, reconstitution chambers and the like. The assay cartridges are used to conduct multiplexed nucleic acid measurements. Also described are kits including such cartridges, methods of using the same, and a reader configured to analyze an assay conducted using an assay cartridge.
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公开(公告)号：US20200057070A1
公开(公告)日：2020-02-20
申请号：US16653268
申请日：2019-10-15
Applicant: Meso Scale Technologies, LLC.
Inventor： Eli N. Glezer , Anu Mathew , Martin Stengelin , Mingyue Wang
IPC: G01N33/574
Abstract: The present invention relates to methods of diagnosing a liver disorder in a patient, as well as methods of monitoring the progression of a liver disorder and/or methods of monitoring a treatment protocol of a therapeutic agent or a chemotherapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.
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公开(公告)号：US20190291103A1
公开(公告)日：2019-09-26
申请号：US16227081
申请日：2018-12-20
Applicant: Meso Scale Technologies, LLC.
Inventor： Eli N. Glezer , Sudeep Kumar , Pankaj Oberoi , George Sigal , Michael Tsionsky
IPC: B01L3/00 , C12Q1/6804 , G01N33/68 , G01N33/543 , C12Q1/6816 , C12Q1/6876
Abstract: The invention relates to methods for conducting solid-phase binding assays. One example is an assay method having improved analyte specificity where specificity is limited by the presence of non-specific binding interactions.
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