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29 条记录 (耗时 0.021 秒)

    LOCALLY TARGETED ANTI-FIBROTIC AGENTS AND METHODS OF USE
    21.
    发明申请
    LOCALLY TARGETED ANTI-FIBROTIC AGENTS AND METHODS OF USE 有权
    局部定向的抗纤维化剂和使用方法

    公开(公告)号：US20120101325A1

    公开(公告)日：2012-04-26

    申请号：US12911967

    申请日：2010-10-26

    申请人： Elaine Lee ,  John Scott Surfus

    发明人： Elaine Lee ,  John Scott Surfus

    IPC分类号： A61K38/47 ,  A61K38/18 ,  A61N2/00 ,  A61P29/00 ,  A61N1/30 ,  A61N7/00 ,  A61K38/22 ,  A61P35/00

    CPC分类号： A61K9/0009 ,  A61K9/0024 ,  A61K47/34 ,  A61M37/0092

    摘要： Effective devices and methods using an antifibrotic agent are provided for treating fibrosis or treating normal fibrous tissue. The devices and methods comprise an antifibrotic agent to degrade shrink, relax or stretch at least a portion of the fibrotic tissue. In some embodiments, the methods and devices are configured to immediately release an effective amount of the antifibrotic agent within 24 hours. In some embodiments, when the device comes in contact directly or indirectly with an activator, the antifibrotic agent will be immediately released from the depot. In some embodiments, the depot provides sustained release of the antifibrotic agent over a period of up to one year to treat fibrous tissue.

    摘要翻译： 提供使用抗纤维化剂的有效装置和方法用于治疗纤维化或治疗正常的纤维组织。 所述装置和方法包括抗纤维化剂以降解收缩，松弛或拉伸纤维组织的至少一部分。 在一些实施方案中，方法和装置被配置为在24小时内立即释放有效量的抗纤维化剂。 在一些实施方案中，当装置直接或间接与活化剂接触时，抗纤维化剂将立即从贮库释放。 在一些实施方案中，贮存库在长达一年的时间内提供抗纤维化剂的持续释放以治疗纤维组织。

    Internal restraint for delivery of self-expanding stents
    25.
    发明授权
    Internal restraint for delivery of self-expanding stents 有权
    自我扩张支架的内部限制

    公开(公告)号：US08303616B2

    公开(公告)日：2012-11-06

    申请号：US11028808

    申请日：2005-01-03

    申请人： Robert M. Abrams ,  Elaine Lee

    发明人： Robert M. Abrams ,  Elaine Lee

    IPC分类号： A61M29/00

    CPC分类号： G06Q10/00 ,  A61F2/95 ,  A61F2002/9511 ,  G06F19/00 ,  G06Q50/22 ,  G06Q50/24

    摘要： A medical device delivery system comprises a catheter having a catheter shaft with a proximal region and a distal region. The catheter shaft has a pull wire lumen therein. An expandable medical device is disposed about medical device receiving region of the catheter shaft. The expandable medical device has a reduced configuration and an expanded configuration. The system further comprises a retractable retaining wire, at least a portion of which is coiled about the expandable medical device and retains the expandable medical device in the reduced configuration. One end of the retractable retaining wire terminates in a pull-wire. The pull-wire extends into the pull-wire lumen to the proximal region of the catheter shaft.

    摘要翻译： 医疗装置输送系统包括具有导管轴的导管，其具有近端区域和远端区域。 导管轴在其中具有拉丝腔。 可扩张医疗装置设置在导管轴的医疗装置接收区域周围。 可扩展医疗设备具有减小的配置和扩展配置。 该系统进一步包括可缩回保持线，其至少一部分围绕可扩张医疗装置卷绕并将可扩张医疗装置保持在减小的构型。 可伸缩保持线的一端终止于拉线。 拉线延伸到拉线管腔到导管轴的近端区域。

    Tissue structure perforation system and method
    26.
    发明授权
    Tissue structure perforation system and method 有权
    组织结构穿孔系统及方法

    公开(公告)号：US08257379B2

    公开(公告)日：2012-09-04

    申请号：US12846117

    申请日：2010-07-29

    申请人： Elaine Lee

    发明人： Elaine Lee

    IPC分类号： A61B17/32

    CPC分类号： A61B17/320036 ,  A61B2017/32113

    摘要： A surgical treatment can involve creating a pattern of perforations in a tissue structure to allow lengthening of that tissue structure. For example, a pattern of perforations can be created in the transverse carpal ligament of a patient suffering from carpal tunnel syndrome (CTS) that allows the carpal ligament to lengthen slightly. This lengthening can relieve pressure on the median nerve, thereby reducing the symptoms of CTS while maintaining the structural integrity of the wrist. A surgical instrument for use in perforating a tissue structure (such as the transverse ligament) can be an elongate structure with one or more retractable blades. Such a tool can be used in either an open or minimally invasive procedure to create a desired pattern of perforations in the tissue structure.

    摘要翻译： 外科治疗可以涉及在组织结构中产生穿孔图案以允许延长该组织结构。 例如，可以在患有腕管综合征（CTS）的患者的横腕腕韧带中产生穿孔图案，其允许腕韧带稍微延长。 这种延长可以减轻正中神经的压力，从而减少CTS的症状，同时保持手腕的结构完整性。 用于穿孔组织结构（例如横向韧带）的手术器械可以是具有一个或多个可缩回刀片的细长结构。 这种工具可用于开放或微创手术中以在组织结构中产生期望的穿孔图案。

    ACTIVATABLE DEVICES CONTAINING A CHEMONUCLEOLYSIS AGENT
    27.
    发明申请
    ACTIVATABLE DEVICES CONTAINING A CHEMONUCLEOLYSIS AGENT 有权
    含有化学药剂的活性成分

    公开(公告)号：US20120101577A1

    公开(公告)日：2012-04-26

    申请号：US12911988

    申请日：2010-10-26

    申请人： Elaine Lee

    发明人： Elaine Lee

    IPC分类号： A61F2/44

    CPC分类号： A61F2/441 ,  A61B17/3415 ,  A61F2/4455 ,  A61F2002/30062 ,  A61F2002/30677 ,  A61F2002/444 ,  A61F2002/4445 ,  A61K38/00

    摘要： Effective devices and methods using a chemonucleolysis agent are provided for treating an intervertebral disc or treating spinal arachnoiditis. The devices and methods comprise a chemonucleolysis agent to degrade or to shrink at least a portion of the intervertebral disc. In some embodiments, the methods and devices are configured to immediately release an effective amount of the chemonucleolysis agent within 24 hours when the device comes in contact directly or indirectly with an activator and provide sustained release of the chemonucleolysis agent over a period of up to one year to treat the intervertebral disc. In some embodiments, the chemonucleolysis agent in the device is administered in or near the intrathecal space and/or thecal sac to treat spinal arachnoiditis.

    摘要翻译： 提供使用化学解毒剂的有效装置和方法用于治疗椎间盘或治疗脊髓蛛网膜炎。 所述装置和方法包括降解或收缩至少一部分椎间盘的化学核解分解剂。 在一些实施方案中，所述方法和装置被配置为当所述装置直接或间接与活化剂接触时在24小时内立即释放有效量的化学解毒剂，并在多至一个时间段内提供化学解毒剂的持续释放 一年治疗椎间盘。 在一些实施方案中，装置中的化学解毒剂在鞘内空间和/或囊囊内或附近施用以治疗脊髓蛛网膜炎。

    Calibrated rolling pin apparatus
    29.
    发明申请
    Calibrated rolling pin apparatus 审中-公开
    校准滚针装置

    公开(公告)号：US20070254791A1

    公开(公告)日：2007-11-01

    申请号：US11413472

    申请日：2006-05-01

    申请人： Elaine Lee

    发明人： Elaine Lee

    IPC分类号： B25F5/02

    CPC分类号： A21C3/021

    摘要： A calibrated rolling pin apparatus includes an axle, a rolling pin drum supported on the axle, handles attached to opposite ends of the rolling pin drum, and measurement indicia applied to portions of the rolling pin drum. The measurement indicia is visible from outside the rolling pin drum. By rolling dough with the measurement indicia in view, the user can readily measure the dimensions of the rolled dough. Preferably, the measurement indicia are formed on an outside surface of the rolling pin drum. The measurement indicia can be in a form of apothecary indicia and/or metric indicia. In addition, a level indicating device is contained within the rolling pin drum and is visible from outside the rolling pin drum through a transparent window in the drum. Also, one of the handles can be in a form of a dough embosser which is used to emboss a portion of the dough when rolled over that portion of the dough.

    摘要翻译： 校准滚针装置包括轴，支撑在轴上的滚针滚筒，附接到滚针滚筒的相对端的手柄，以及施加到滚针滚筒的部分的测量标记。 测量标记从滚针滚筒的外侧可见。 通过使用测量标记滚动面团，用户可以容易地测量轧制面团的尺寸。 优选地，测量标记形成在滚针滚筒的外表面上。 测量标记可以是药剂师标记和/或度量标记的形式。 此外，水平指示装置容纳在滚针滚筒内，并且通过滚筒中的透明窗可从滚筒滚筒外部看到。 另外，其中一个手柄可以是一种面团式压花机的形式，当在面团的该部分上滚动时，其用于压制一部分面团。