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    Flexible circuit electrode array
    21.
    发明申请
    Flexible circuit electrode array 有权

    公开(公告)号：US20060247754A1

    公开(公告)日：2006-11-02

    申请号：US11207644

    申请日：2005-08-19

    Applicant: Robert Greenberg ,  Neil Talbot ,  Jordan Neysmith ,  Dilek Guven ,  James Little ,  Brian Mech ,  Mark Humayun

    Inventor： Robert Greenberg ,  Neil Talbot ,  Jordan Neysmith ,  Dilek Guven ,  James Little ,  Brian Mech ,  Mark Humayun

    IPC: A61N1/05

    CPC classification number: H05K3/0011 ,  A61N1/0541 ,  A61N1/0543 ,  A61N1/36036 ,  A61N1/36046 ,  Y10T29/49124

    Abstract: Polymer materials are useful as electrode array bodies for neural stimulation. They are particularly useful for retinal stimulation to create artificial vision, cochlear stimulation to create artificial hearing, or cortical stimulation many purposes. The pressure applied against the retina, or other neural tissue, by an electrode array is critical. Too little pressure causes increased electrical resistance, along with electric field dispersion. Too much pressure may block blood flow. Common flexible circuit fabrication techniques generally require that a flexible circuit electrode array be made flat. Since neural tissue is almost never flat, a flat array will necessarily apply uneven pressure. Further, the edges of a flexible circuit polymer array may be sharp and cut the delicate neural tissue. By applying the right amount of heat to a completed array, a curve can be induced. With a thermoplastic polymer it may be further advantageous to repeatedly heat the flexible circuit in multiple molds, each with a decreasing radius. Further, it is advantageous to add material along the edges. It is further advantageous to provide a fold or twist in the flexible circuit array. Additional material may be added inside and outside the fold to promote a good seal with tissue.

    Visual prosthesis including enhanced receiving and stimulating portion
    22.
    发明授权
    Visual prosthesis including enhanced receiving and stimulating portion 有权
    视觉假体包括增强的接收和刺激部分

    公开(公告)号：US07103416B2

    公开(公告)日：2006-09-05

    申请号：US09761270

    申请日：2001-01-16

    Applicant: Jerry Ok ,  Robert J. Greenberg ,  Mark Humayun

    Inventor： Jerry Ok ,  Robert J. Greenberg ,  Mark Humayun

    IPC: A61N1/08

    CPC classification number: A61F2/14 ,  A61N1/0543 ,  A61N1/36046

    Abstract: A visual prosthesis including an enhanced receiving and stimulating portion for electrically stimulating retinal tissue to present an apparent image to a user. The prosthesis includes an extracellular camera which responds to a real image to generate a real image signal. The real image signal is coupled, e.g., RF coupling, from an extracellular primary coil to a secondary coil. The secondary coil is preferably affixed within the vitreous body of the user's eye positioned for good signal coupling to the primary coil and arranged to be in good thermal contact with the vitreous body which acts as a heat sink. A hermetically sealed housing containing signal processing circuitry is also preferably placed in the vitreous body to assure efficient heat transfer away from the housing. The circuitry is electrically connected to the secondary coil and responds to an output signal therefrom to produce an apparent image signal for driving an electrode array. The electrode array is configured to electrically stimulate the eye's retinal tissue to enable a user to perceive an apparent image.

    Abstract translation: 一种视觉假体，包括用于电刺激视网膜组织以向用户呈现明显图像的增强的接收和刺激部分。 假体包括对真实图像进行响应以生成实像信号的细胞外相机。 真实图像信号从细胞外初级线圈耦合到例如RF耦合到次级线圈。 次级线圈优选地固定在用户眼睛的玻璃体内，用于良好的信号耦合到初级线圈并被布置成与用作散热器的玻璃体良好的热接触。 包含信号处理电路的气密密封的壳体也优选放置在玻璃体中，以确保远离壳体的有效热传递。 电路电连接到次级线圈并响应于其输出信号以产生用于驱动电极阵列的视在信号。 电极阵列被配置为电刺激眼睛的视网膜组织以使得使用者能够感知视觉图像。

    Digital object recognition audio-assistant for the visually impaired
    24.
    发明申请
    Digital object recognition audio-assistant for the visually impaired 审中-公开
    视觉障碍者的数字对象识别音频助理

    公开(公告)号：US20050208457A1

    公开(公告)日：2005-09-22

    申请号：US11030678

    申请日：2005-01-05

    Applicant: Wolfgang Fink ,  Mark Humayun

    Inventor： Wolfgang Fink ,  Mark Humayun

    IPC: G09B21/00

    CPC classification number: G09B21/00

    Abstract: A camera-based object detection system for a severely visually impaired or blind person consisting a digital camera mounted on the person's eyeglass or head that takes images on demand. Near-real time image processing algorithms decipher certain attributes of the captured image by processing it for edge pattern detection within a central region of the image. The results are classified by artificial neural networks trained on a list of known objects, in a look up table, or by a threshold. Once the pattern is classified a descriptive sentence is constructed of the object and its certain attributes and a computer-based voice synthesizer is used to verbally announce the descriptive sentence. The invention is used to determine the size of an object, or its distance from another object, and can be used in conjunction with an IR-sensitive camera to provide “sight” in poor visibility conditions, or at night.

    Abstract translation: 一种用于严重视觉障碍或盲人的摄像机物体检测系统，包括安装在人眼镜或头上的数字照相机，其根据需要拍摄图像。 近实时图像处理算法通过对图像的中心区域中的边缘图案检测进行处理来解码捕获图像的某些属性。 结果通过在已知对象的列表，查找表中或通过阈值训练的人造神经网络进行分类。 一旦模式被分类，描述性句子由对象及其某些属性构成，并且使用基于计算机的语音合成器来口头公布描述性句子。 本发明用于确定物体的尺寸或其与另一物体的距离，并且可以与IR敏感相机结合使用，以在较差的可视性条件或夜间提供“视线”。

    THROMBOLYSIS IN RETINAL VESSELS WITH ULTRASOUND
    29.
    发明申请
    THROMBOLYSIS IN RETINAL VESSELS WITH ULTRASOUND 审中-公开
    超声波血管内血栓形成

    公开(公告)号：US20140243712A1

    公开(公告)日：2014-08-28

    申请号：US13780535

    申请日：2013-02-28

    Applicant: Mark Humayun ,  Xiaochen Xu ,  Qifa Zhou ,  K. Kirk Shung ,  Hossein Ameri ,  Gerald Chader

    Inventor： Mark Humayun ,  Xiaochen Xu ,  Qifa Zhou ,  K. Kirk Shung ,  Hossein Ameri ,  Gerald Chader

    IPC: A61N7/00

    CPC classification number: A61N7/00 ,  A61B17/22012 ,  A61F9/00745 ,  A61N2007/0047

    Abstract: Systems and methods are described providing for the use of ultrasound energy to effect the dislodging of one or more blood clots inside blood vessels. Such clots can include those inside retinal vessels, especially in patients with central retinal vein occlusion. Embodiments of the present disclosure may be used for any retinal arterial or venous occlusion. In exemplary embodiments, a small probe can be inserted into the eye of a patient and placed over the retinal vessels. Acoustic streaming created by the probe can be directed to an area or region including targeted blood vessels, resulting in increased flow in one or more retinal veins and facilitating or effecting mechanical dislodging of one or more blood clots in the targets blood vessels. Exemplary embodiments can utilize ultrasonic energy produced at a frequency of approximately 44 MHz to 46 MHz with pulse repetition frequencies of approximately 100 Hz to 100 kHz.

    Abstract translation: 描述了使用超声能量来实现血管内的一个或多个血块的移动的系统和方法。 视网膜血管，包括视网膜中央静脉阻塞的患者尤其如此。 本公开的实施方案可用于任何视网膜动脉或静脉闭塞。 在示例性实施例中，可以将小探针插入患者的眼睛并放置在视网膜血管上。 由探针产生的声流可以被引导到包括目标血管的区域或区域，导致一个或多个视网膜静脉中的流量增加并且促进或实现靶血管中的一个或多个血块的机械移除。 示例性实施例可以利用大约44MHz至46MHz的频率产生的超声能量，脉冲重复频率约为100Hz至100kHz。

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